Peter G Steinherz

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. pmc Autonomous growth potential of leukemia blast cells is associated with poor prognosis in human acute leukemias
    Ying Yan
    The Saint Luke s Cancer Institute, 4321 Washington, Suite 4000 Kansas City, Missouri 64111, USA
    J Hematol Oncol 2:51. 2009
  2. ncbi request reprint Phase I study of gemcitabine (difluorodeoxycytidine) in children with relapsed or refractory leukemia (CCG-0955): a report from the Children's Cancer Group
    P G Steinherz
    Leuk Lymphoma 43:1945-50. 2002
  3. ncbi request reprint Clofarabine induced durable complete remission in heavily pretreated adolescents with relapsed and refractory leukemia
    Peter G Steinherz
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Pediatr Hematol Oncol 29:656-8. 2007
  4. ncbi request reprint Human granulocyte colony-stimulating factor in children with high-risk acute lymphoblastic leukemia: a Children's Cancer Group Study
    John A Heath
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    J Clin Oncol 21:1612-7. 2003
  5. doi request reprint Effect of hemodialysis on the plasma levels of clofarabine
    Peter G Steinherz
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Pediatr Blood Cancer 55:196-8. 2010
  6. doi request reprint Remission re-induction chemotherapy with clofarabine, topotecan, thiotepa, and vinorelbine for patients with relapsed or refractory leukemia
    Peter G Steinherz
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Pediatr Blood Cancer 54:687-93. 2010
  7. ncbi request reprint Imatinib mesylate in Philadelphia chromosome-positive leukemia of childhood
    E Anders Kolb
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer 98:2643-50. 2003
  8. ncbi request reprint Improved long-term survival with combined modality therapy for pediatric nasopharynx cancer
    S L Wolden
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Int J Radiat Oncol Biol Phys 46:859-64. 2000
  9. doi request reprint Allogeneic hematopoietic stem cell transplantation for pediatric patients with treatment-related myelodysplastic syndrome or acute myelogenous leukemia
    Rachel Kobos
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Biol Blood Marrow Transplant 18:473-80. 2012
  10. doi request reprint Factors associated with relapse and survival in Wilms tumor: a multivariate analysis
    Joshua N Honeyman
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Pediatr Surg 47:1228-33. 2012

Research Grants

  1. CHILDRENS CANCER GROUP
    Peter Steinherz; Fiscal Year: 2002

Collaborators

Detail Information

Publications20

  1. pmc Autonomous growth potential of leukemia blast cells is associated with poor prognosis in human acute leukemias
    Ying Yan
    The Saint Luke s Cancer Institute, 4321 Washington, Suite 4000 Kansas City, Missouri 64111, USA
    J Hematol Oncol 2:51. 2009
    ..Patients whose leukemic blasts grew indolently or whose leukemia cells failed to induce growth had a significantly longer DFS and more favorable clinical course...
  2. ncbi request reprint Phase I study of gemcitabine (difluorodeoxycytidine) in children with relapsed or refractory leukemia (CCG-0955): a report from the Children's Cancer Group
    P G Steinherz
    Leuk Lymphoma 43:1945-50. 2002
    ..This is the recommended phase II dose schedule for children with leukemia. The activity of the drug at this schedule in heavily pretreated, refractory patients warrants a phase II trial in hematologic malignancies...
  3. ncbi request reprint Clofarabine induced durable complete remission in heavily pretreated adolescents with relapsed and refractory leukemia
    Peter G Steinherz
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Pediatr Hematol Oncol 29:656-8. 2007
    ..The remissions were sustained with repeated cycles of monotherapy for 47, 59, and 64 weeks, respectively...
  4. ncbi request reprint Human granulocyte colony-stimulating factor in children with high-risk acute lymphoblastic leukemia: a Children's Cancer Group Study
    John A Heath
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    J Clin Oncol 21:1612-7. 2003
    ....
  5. doi request reprint Effect of hemodialysis on the plasma levels of clofarabine
    Peter G Steinherz
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Pediatr Blood Cancer 55:196-8. 2010
    ..Post-dialysis, while the clofarabine was still infusing, the level was 95.8 ng/ml. Hemodialysis does decrease clofarabine levels, but given its large volume distribution, hemodialysis may not be effective for clofarabine overdose...
  6. doi request reprint Remission re-induction chemotherapy with clofarabine, topotecan, thiotepa, and vinorelbine for patients with relapsed or refractory leukemia
    Peter G Steinherz
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Pediatr Blood Cancer 54:687-93. 2010
    ....
  7. ncbi request reprint Imatinib mesylate in Philadelphia chromosome-positive leukemia of childhood
    E Anders Kolb
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer 98:2643-50. 2003
    ..However, to our knowledge, there are few data regarding imatinib safety, efficacy, and response monitoring in patients age < 18 years...
  8. ncbi request reprint Improved long-term survival with combined modality therapy for pediatric nasopharynx cancer
    S L Wolden
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Int J Radiat Oncol Biol Phys 46:859-64. 2000
    ..Nasopharynx cancer is a rare malignancy in childhood. This study aims to determine the role of chemotherapy, the optimal dose of radiation, and the long-term outcome for children with locoregional disease...
  9. doi request reprint Allogeneic hematopoietic stem cell transplantation for pediatric patients with treatment-related myelodysplastic syndrome or acute myelogenous leukemia
    Rachel Kobos
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Biol Blood Marrow Transplant 18:473-80. 2012
    ..In addition, the use of a TCD transplantation with BU-MEL-FLU as cytoreduction may decrease the toxicity of transplantation in heavily pretreated patients without an increase in relapse rate...
  10. doi request reprint Factors associated with relapse and survival in Wilms tumor: a multivariate analysis
    Joshua N Honeyman
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Pediatr Surg 47:1228-33. 2012
    ..Lymph node metastasis and anaplasia predict relapse-free survival in Wilms tumor. We performed a multivariate analysis of our institutional database to identify factors independently associated with relapse-free and overall survival...
  11. doi request reprint Eradication of cryptosporidium from a defunctionalized colon limb by refeeding stoma effluent
    Emma L Sidebotham
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Pediatr Surg 45:E33-6. 2010
    ..Refeeding of the ileostomy output into the colon effectively eradicated cryptosporidium from the colon and permitted closure of the ileostomy...
  12. ncbi request reprint Reduced folate carrier and dihydrofolate reductase expression in acute lymphocytic leukemia may predict outcome: a Children's Cancer Group Study
    Adam S Levy
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Pediatr Hematol Oncol 25:688-95. 2003
    ..The purpose of this study was to assess whether reduced folate carrier (RFC) and DHFR expression in untreated leukemic blasts correlated with outcome...
  13. ncbi request reprint Pythium insidiosum pleuropericarditis complicating pneumonia in a child with leukemia
    John A Heath
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, 10021, USA
    Clin Infect Dis 35:E60-4. 2002
    ..After completing a 12-month course of intravenously administered liposomal amphotericin B (AmBisome; Fujisawa Healthcare) and itraconazole, the patient remained alive, in clinical remission, and symptom free...
  14. ncbi request reprint Late cardiotoxicity after bolus versus infusion anthracycline therapy for childhood cancers
    Monesha Gupta
    Department of Pediatrics, Division of Cardiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Med Pediatr Oncol 40:343-7. 2003
    ..To compare the long-term myocardial function of patients who had been treated with infusion anthracycline therapy (administered continuously over >24 hr, IG) versus bolus therapy (administered over <30 min, BG)...
  15. ncbi request reprint A new multidrug reinduction protocol with topotecan, vinorelbine, thiotepa, dexamethasone, and gemcitabine for relapsed or refractory acute leukemia
    E A Kolb
    Department of Pediatrics at Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Leukemia 17:1967-72. 2003
    ..Further studies are warranted to evaluate the role of the TVTG combination in the treatment of leukemia...
  16. ncbi request reprint Diaziquone and 2,2'-anhydro-arabinosyl-5-fluorocytosine for the treatment of children with relapsed or refractory acute nonlymphoblastic leukemia
    P A Meyers
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021
    Cancer 64:2416-9. 1989
    ..Although AZQ and AAFC are active in childhood ANLL with acceptable toxicity, the combination does not appear more active than AZQ used alone. Future studies should define the role of AZQ in combination with other agents...
  17. doi request reprint Ten-year survival of children with acute lymphoblastic leukemia: a report from the Children's Oncology Group
    Michael E Trigg
    Jefferson Medical College, Thomas Jefferson University, USA
    Leuk Lymphoma 49:1142-54. 2008
    ..This is the largest series of children on concurrent studies who were observed more than 10 years...
  18. ncbi request reprint Pediatric AML: past, present, and future
    Kenan Onel
    Cancer Invest 20:1117. 2002
  19. pmc Early postinduction intensification therapy improves survival for children and adolescents with high-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group
    Nita L Seibel
    Hematology Oncology, Children s National Medical Center and George Washington University School of Medicine and Public Health, 111 Michigan Avenue NW, Washington, DC 20010, USA
    Blood 111:2548-55. 2008
    ..Longer duration PII provided no benefit. Stronger intensity but not prolonged duration PII improved outcome for patients with higher-risk ALL. This study is registered at http://clinicaltrials.gov as NCT00002812...
  20. ncbi request reprint Methotrexate leukoencephalopathy presenting as Klüver-Bucy syndrome and uncinate seizures
    Nuno Lobo Antunes
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Pediatr Neurol 26:305-8. 2002
    ..It may be prudent to verify normal cerebrospinal fluid dynamics before the administration of intraventricular methotrexate in children with a history of central nervous system leukemia...

Research Grants1

  1. CHILDRENS CANCER GROUP
    Peter Steinherz; Fiscal Year: 2002
    ..Members of the affiliate hospitals have been participating in CCG studies and have proven their ability to conduct the clinical studies and provide material for laboratory evaluation. ..