R A Soslow

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. doi request reprint Clinicopathologic analysis of matched primary and recurrent endometrial carcinoma
    Robert A Soslow
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Surg Pathol 36:1771-81. 2012
  2. ncbi request reprint COX-2 is expressed in human pulmonary, colonic, and mammary tumors
    R A Soslow
    Department of Pathology, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, New York 10021, USA
    Cancer 89:2637-45. 2000
  3. ncbi request reprint Clinicopathologic analysis of 187 high-grade endometrial carcinomas of different histologic subtypes: similar outcomes belie distinctive biologic differences
    Robert A Soslow
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 31:979-87. 2007
  4. doi request reprint Histologic subtypes of ovarian carcinoma: an overview
    Robert A Soslow
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Int J Gynecol Pathol 27:161-74. 2008
  5. doi request reprint Mullerian adenosarcomas: an immunophenotypic analysis of 35 cases
    Robert A Soslow
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 32:1013-21. 2008
  6. ncbi request reprint Endometrial carcinomas with ambiguous features
    Robert A Soslow
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Semin Diagn Pathol 27:261-73. 2010
  7. ncbi request reprint Suppression of apoptosis does not foster neoplastic growth in Barrett's esophagus
    R A Soslow
    Department of Pathology, New York Presbyterian Hospital Weill Medical College of Cornell University, New York City 10021, USA
    Mod Pathol 12:239-50. 1999
  8. ncbi request reprint mdm-2 expression correlates with wild-type p53 status in esophageal adenocarcinoma
    R A Soslow
    Department of Pathology, New York Presbyterian Hospital Weill Medical College, Cornell University, New York City 10021, USA
    Mod Pathol 12:580-6. 1999
  9. doi request reprint Clinicopathologic significance of DNA mismatch repair protein defects and endometrial cancer in women 40years of age and younger
    K K Shih
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, United States
    Gynecol Oncol 123:88-94. 2011
  10. ncbi request reprint Endometrial and ovarian carcinomas with undifferentiated components: clinically aggressive and frequently underrecognized neoplasms
    Laura J Tafe
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Mod Pathol 23:781-9. 2010

Detail Information

Publications92

  1. doi request reprint Clinicopathologic analysis of matched primary and recurrent endometrial carcinoma
    Robert A Soslow
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Surg Pathol 36:1771-81. 2012
    ..However, in light of the PR results, sampling a recurrent endometrioid carcinoma may be worthwhile if hormonal therapy is planned. Recurrent endometrioid carcinoma may be enriched for tumors with DNA MMR abnormalities...
  2. ncbi request reprint COX-2 is expressed in human pulmonary, colonic, and mammary tumors
    R A Soslow
    Department of Pathology, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, New York 10021, USA
    Cancer 89:2637-45. 2000
    ..The inducible form of COX, COX-2, has been shown to be important in carcinogenesis...
  3. ncbi request reprint Clinicopathologic analysis of 187 high-grade endometrial carcinomas of different histologic subtypes: similar outcomes belie distinctive biologic differences
    Robert A Soslow
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 31:979-87. 2007
    ....
  4. doi request reprint Histologic subtypes of ovarian carcinoma: an overview
    Robert A Soslow
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Int J Gynecol Pathol 27:161-74. 2008
    ..Clinical biology, immunohistochemistry, and genotype can be used to enhance diagnostic objectivity...
  5. doi request reprint Mullerian adenosarcomas: an immunophenotypic analysis of 35 cases
    Robert A Soslow
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 32:1013-21. 2008
    ..ER, PR, and CD10 expression was lost in MA-SOs relative to conventional low-grade stromal areas of mullerian/mesodermal adenosarcomas, reflecting the "dedifferentiation" of this component...
  6. ncbi request reprint Endometrial carcinomas with ambiguous features
    Robert A Soslow
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Semin Diagn Pathol 27:261-73. 2010
    ....
  7. ncbi request reprint Suppression of apoptosis does not foster neoplastic growth in Barrett's esophagus
    R A Soslow
    Department of Pathology, New York Presbyterian Hospital Weill Medical College of Cornell University, New York City 10021, USA
    Mod Pathol 12:239-50. 1999
    ..These observations will lead to a better understanding of the pathogenesis of esophageal adenocarcinoma and might contribute to enhancing the diagnostic accuracy when presented with dysplastic lesions...
  8. ncbi request reprint mdm-2 expression correlates with wild-type p53 status in esophageal adenocarcinoma
    R A Soslow
    Department of Pathology, New York Presbyterian Hospital Weill Medical College, Cornell University, New York City 10021, USA
    Mod Pathol 12:580-6. 1999
    ..In cases without p53 mutation, overexpression of mdm-2 occurred in 50% of cases and might be responsible for stabilization of p53 protein and possible loss of tumor suppressor function...
  9. doi request reprint Clinicopathologic significance of DNA mismatch repair protein defects and endometrial cancer in women 40years of age and younger
    K K Shih
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, United States
    Gynecol Oncol 123:88-94. 2011
    ..The hereditary basis of endometrial cancer is apparent in young women with endometrial cancer. The objective of this study was to examine risk factors and outcomes in patients 40 years of age and younger with endometrial cancer...
  10. ncbi request reprint Endometrial and ovarian carcinomas with undifferentiated components: clinically aggressive and frequently underrecognized neoplasms
    Laura J Tafe
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Mod Pathol 23:781-9. 2010
    ..These tumors can occur in young women, may be associated with microsatellite instability and behave in a clinically aggressive manner...
  11. doi request reprint Accuracy of frozen section diagnosis of ovarian borderline tumor
    K K Shih
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Gynecol Oncol 123:517-21. 2011
    ..The objective of this study was to determine the incidence of invasive cancer in ovarian masses diagnosed as borderline tumor (BT) at the time of frozen section...
  12. doi request reprint Impact of incorporating an algorithm that utilizes sentinel lymph node mapping during minimally invasive procedures on the detection of stage IIIC endometrial cancer
    M M Leitao
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Gynecol Oncol 129:38-41. 2013
    ..To determine whether the frequency of cases diagnosed with stage IIIC endometrial cancer is affected by the incorporation of a modified surgical lymph node assessment...
  13. ncbi request reprint Inducible microsomal prostaglandin E synthase is overexpressed in colorectal adenomas and cancer
    K Yoshimatsu
    Department of Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA
    Clin Cancer Res 7:3971-6. 2001
    ..The mechanisms controlling the expression of these two enzymes are not identical...
  14. doi request reprint Complex atypical hyperplasia of the uterus: characteristics and prediction of underlying carcinoma risk
    Mario M Leitao
    Division of Gynecology, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Obstet Gynecol 203:349.e1-6. 2010
    ..The objective of the study was to identify additional factors that may improve the ability to predict underlying carcinoma risk in patients with complex atypical hyperplasia (CAH) of the uterus...
  15. ncbi request reprint The CD44v6-negative phenotype in high-grade uterine carcinomas correlates with serous histologic subtype
    R A Soslow
    Department of Pathology, New York Hospital Cornell Medical Center, New York 10021, USA
    Mod Pathol 11:194-9. 1998
    ..In summary, the USCs were significantly more likely to demonstrate a CD44- and CD44v6-negative phenotype than were the poorly differentiated ECs...
  16. ncbi request reprint Radiation-associated endometrial cancers are prognostically unfavorable tumors: a clinicopathologic comparison with 527 sporadic endometrial cancers
    Bhavana Pothuri
    Department of Obstetrics and Gynecology, Columbia University, New York, NY, USA
    Gynecol Oncol 103:948-51. 2006
    ..Previous reports have suggested that patients who have undergone pelvic radiation for cervical cancer are at risk for developing poorly differentiated endometrial cancers with poor prognoses...
  17. ncbi request reprint Prognostic features of surgical stage I uterine carcinosarcoma
    Sarah E Ferguson
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 31:1653-61. 2007
    ..More importantly, the presence of heterologous sarcomatous elements is a powerful negative prognostic factor in surgical stage I uterine CS...
  18. doi request reprint Accuracy of preoperative endometrial sampling diagnosis of FIGO grade 1 endometrial adenocarcinoma
    Mario M Leitao
    Department of Surgery, Division of Gynecology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Gynecol Oncol 111:244-8. 2008
    ..To evaluate the ability of a preoperative diagnosis of FIGO grade 1 endometrial adenocarcinoma and intraoperative depth of myoinvasion (DOI) to predict low-risk (LR) and high-risk (HR) final uterine pathology...
  19. ncbi request reprint Duodenal reflux induces cyclooxygenase-2 in the esophageal mucosa of rats: evidence for involvement of bile acids
    F Zhang
    Department of Cardiothoracic Surgery, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA
    Gastroenterology 121:1391-9. 2001
    ..CONCLUSIONS: Reflux of duodenal contents into the esophagus led to increased COX-2 expression and mucosal thickening. Bile acids are likely to contribute to these effects...
  20. doi request reprint Ovarian clear cell carcinoma with papillary features: a potential mimic of serous tumor of low malignant potential
    Ankur R Sangoi
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    Am J Surg Pathol 32:269-74. 2008
    ..As CCC and S-LMP exhibit significantly different immunoreactivity for Wilms' Tumor 1 and estrogen receptor, these markers may also be useful adjunctive tests in problematic cases...
  21. ncbi request reprint Immunophenotypic diversity of endometrial adenocarcinomas: implications for differential diagnosis
    Michelle Reid-Nicholson
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Mod Pathol 19:1091-100. 2006
    ..In contrast, the vimentin-positive/CEA-negative phenotype remained the most constant among all endometrial cancers...
  22. doi request reprint Endometrial carcinomas in women aged 40 years and younger: tumors associated with loss of DNA mismatch repair proteins comprise a distinct clinicopathologic subset
    Karuna Garg
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Surg Pathol 33:1869-77. 2009
    ..Although young EC patients are at increased risk for synchronous endometrioid ovarian carcinomas, this does not seem to be associated with MMR loss...
  23. doi request reprint Extrauterine epithelioid trophoblastic tumors presenting as primary lung carcinomas: morphologic and immunohistochemical features to resolve a diagnostic dilemma
    Sharyn N Lewin
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Surg Pathol 33:1809-14. 2009
    ..Correlating clinical indices with specific morphologic and immunohistochemical features can ensure diagnostic accuracy and appropriate treatment for favorable outcomes...
  24. pmc Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas
    Xingxing Zang
    Howard Hughes Medical Institute, Immunology Program, Ludwig Center for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Mod Pathol 23:1104-12. 2010
    ..B7-H3 expression in tumor vasculature may be a reflection of tumor aggressiveness and has diagnostic and immunotherapeutic implications in ovarian carcinomas...
  25. doi request reprint Ependymomas of the central nervous system and adult extra-axial ependymomas are morphologically and immunohistochemically distinct--a comparative study with assessment of ovarian carcinomas for expression of glial fibrillary acidic protein
    Michael O Idowu
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 32:710-8. 2008
    ..ER and PR expression in extra-axial ependymomas may provide targets for hormonal therapy...
  26. ncbi request reprint Utility of immunohistochemistry in predicting microsatellite instability in endometrial carcinoma
    Ippolito Modica
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 31:744-51. 2007
    ..In the future, as prognostic and therapeutic implications of MSI phenotype become better defined, it may be reasonable to perform IHC for mismatch repair proteins in large numbers of endometrial carcinomas...
  27. doi request reprint Endometrial sampling diagnosis of FIGO grade 1 endometrial adenocarcinoma with a background of complex atypical hyperplasia and final hysterectomy pathology
    Mario M Leitao
    Division of Gynecology, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Obstet Gynecol 202:278.e1-6. 2010
    ....
  28. doi request reprint Comparison of D&C and office endometrial biopsy accuracy in patients with FIGO grade 1 endometrial adenocarcinoma
    Mario M Leitao
    Department of Surgery, Division of Gynecology, Memorial Sloan Kettering Cancer Center 1275 York Avenue New York, NY 10065, USA
    Gynecol Oncol 113:105-8. 2009
    ..To compare the accuracy of D&C vs office endometrial biopsy in predicting final post-hysterectomy FIGO grade in patients diagnosed with a preoperative FIGO grade 1 endometrial adenocarcinoma...
  29. doi request reprint Is there a therapeutic impact to regional lymphadenectomy in the surgical treatment of endometrial carcinoma?
    Nadeem R Abu-Rustum
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Obstet Gynecol 198:457.e1-5; discussion 457.e5-6. 2008
    ..The objective of the study was to evaluate whether surgical removal of regional lymph nodes influences the overall survival of women with endometrial carcinoma...
  30. ncbi request reprint The incidence of isolated paraaortic nodal metastasis in surgically staged endometrial cancer patients with negative pelvic lymph nodes
    Nadeem R Abu-Rustum
    Memorial Sloan Kettering Cancer Centerm, 1275 York Ave, NY, NY 10065, USA
    Gynecol Oncol 115:236-8. 2009
    ..To describe the incidence of isolated paraaortic nodal metastasis in surgically staged endometrial cancer patients with negative pelvic lymph nodes...
  31. doi request reprint Perihepatic metastases from ovarian cancer: sensitivity and specificity of CT for the detection of metastases with and those without liver parenchymal invasion
    Oguz Akin
    Departments of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Radiology 248:511-7. 2008
    ....
  32. doi request reprint Frozen-section evaluation of cervical adenocarcinoma at time of radical trachelectomy: pathologic pitfalls and the application of an objective scoring system
    Kay J Park
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Gynecol Oncol 110:316-23. 2008
    ....
  33. doi request reprint Characterization of adnexal masses using feature analysis at contrast-enhanced helical computed tomography
    Jingbo Zhang
    Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Comput Assist Tomogr 32:533-40. 2008
    ..To determine the computed tomographic imaging features predictive of adnexal malignancy and evaluate the accuracy of contrast-enhanced helical computed tomography (CT) in the characterization of adnexal masses...
  34. doi request reprint Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendix
    Laura H Tang
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Surg Pathol 32:1429-43. 2008
    ..Surgical management with right hemicolectomy is recommended after appendectomy for most cases, particularly those with an adenocarcinoma component (groups B and C)...
  35. doi request reprint Expression of pax8 as a useful marker in distinguishing ovarian carcinomas from mammary carcinomas
    Daisuke Nonaka
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Am J Surg Pathol 32:1566-71. 2008
    ....
  36. doi request reprint Current concepts in cervical pathology
    Kay J Park
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Arch Pathol Lab Med 133:729-38. 2009
    ..The correct diagnosis and reporting of cervical in situ and invasive carcinoma are essential for the appropriate clinical management of patients with human papillomavirus-associated disease...
  37. pmc Concurrent carboplatin/paclitaxel and intravaginal radiation in surgical stage I-II serous endometrial cancer
    Kaled M Alektiar
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Gynecol Oncol 112:142-5. 2009
    ..To report a single institution experience in surgical stage I-II serous endometrial cancer using combined carboplatin/paclitaxel and intravaginal radiation (IVRT)...
  38. pmc Sentinel lymph node mapping for grade 1 endometrial cancer: is it the answer to the surgical staging dilemma?
    Nadeem R Abu-Rustum
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Gynecol Oncol 113:163-9. 2009
    ..To describe the accuracy of SLN mapping in patients with a preoperative diagnosis of grade 1 endometrial cancer...
  39. ncbi request reprint Clinicopathologic analysis of early-stage sporadic ovarian carcinoma
    Mario M Leitao
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center New York, NY 10021, USA
    Am J Surg Pathol 28:147-59. 2004
    ..Clear cell histology does not confer a worse prognosis compared with other histologies. The presence of a TP53 mutation was an adverse prognostic indicator...
  40. pmc Induction of ovarian cancer by defined multiple genetic changes in a mouse model system
    Sandra Orsulic
    Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Cancer Cell 1:53-62. 2002
    ..The induced ovarian tumors in mice resembled human ovarian carcinomas in their rapid progression and intraperitoneal metastatic spread...
  41. ncbi request reprint Problems with the current diagnostic approach to complex atypical endometrial hyperplasia
    Robert A Soslow
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10011, USA
    Cancer 106:729-31. 2006
  42. ncbi request reprint Serous endometrial cancers that mimic endometrioid adenocarcinomas: a clinicopathologic and immunohistochemical study of a group of problematic cases
    Farbod Darvishian
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 28:1568-78. 2004
    ..We sought an immunohistochemical panel to minimize subjectivity in the distinction of USC from EEC...
  43. ncbi request reprint Endometrial stromal sarcomas with unusual histologic features: a report of 24 primary and metastatic tumors emphasizing fibroblastic and smooth muscle differentiation
    Asli Yilmaz
    Department of Pathology, Memorial Sloan Kettering Cancer Center and Weill Medical College of Cornell University, New York, NY 10021, USA
    Am J Surg Pathol 26:1142-50. 2002
    ....
  44. ncbi request reprint Expression of cancer-testis antigens in endometrial carcinomas using a tissue microarray
    Dhananjay A Chitale
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Mod Pathol 18:119-26. 2005
    ..CT antigens CT7, MAGE-A3 and MAGE-A4, but not NY-ESO-1, are expressed in high-grade endometrial carcinomas, and expression of MAGE-A4 is correlated with the presence of overexpressed p53...
  45. ncbi request reprint Distinction of endometrial stromal sarcomas from 'hemangiopericytomatous' tumors using a panel of immunohistochemical stains
    Rohit Bhargava
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Mod Pathol 18:40-7. 2005
    ..We therefore recommend the use of a small antibody panel comprising anti-CD10, anti-estrogen receptor, and anti-CD34 to distinguish endometrial stromal sarcomas from tumors with a predominant hemangiopericytomatous growth pattern...
  46. ncbi request reprint A comparative analysis of 57 serous borderline tumors with and without a noninvasive micropapillary component
    Brian M Slomovitz
    Department of Obstetrics and Gynecology, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, New York, USA
    Am J Surg Pathol 26:592-600. 2002
    ..Stage I MSBTs demonstrate clinical features that are similar to low-stage SBTs. Focal micropapillary architecture (<5 mm) has no bearing on outcome. MSBTs in the general population are not strongly associated with invasive implants...
  47. ncbi request reprint Her-2/neu expression and amplification in early stage ovarian surface epithelial neoplasms
    Yun Wu
    Department of Pathology, Division of Gynecology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Gynecol Oncol 95:570-5. 2004
    ..This study is focused on early stage tumors including both carcinomas and borderline tumors...
  48. ncbi request reprint Invasion patterns in stage I endometrioid and mucinous ovarian carcinomas: a clinicopathologic analysis emphasizing favorable outcomes in carcinomas without destructive stromal invasion and the occasional malignant course of carcinomas with limited destru
    Shirley Chen
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Mod Pathol 18:903-11. 2005
    ..In contrast, carcinomas harboring even limited foci of destructive stromal invasion, although frequently cured surgically, can pursue a malignant clinical course...
  49. doi request reprint Immunohistochemistry as first-line screening for detecting colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome: a 2-antibody panel may be as predictive as a 4-antibody panel
    Jinru Shia
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Am J Surg Pathol 33:1639-45. 2009
    ..Such a cost-effective approach carries significant implication, as immunohistochemistry is being widely used as first-line screening for HNPCC...
  50. doi request reprint Patterns of recurrence and role of adjuvant chemotherapy in stage II-IV serous ovarian borderline tumors
    Karin K Shih
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Gynecol Oncol 119:270-3. 2010
    ..The objective of this study was to evaluate patterns of recurrence and prognostic factors as well as the role of adjuvant chemotherapy in stage II-IV ovarian SBT...
  51. ncbi request reprint Squamous cell carcinoma arising in mature cystic teratoma of the ovary: a case series and review of the literature
    Lisa Dos Santos
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Gynecol Oncol 105:321-4. 2007
    ..The prognosis is generally poor when disease has spread beyond the ovary. We conducted this study to review our experience with this disease and describe our current treatment modality...
  52. ncbi request reprint A comparison of cell cycle markers in well-differentiated lobular and ductal carcinomas
    R A Soslow
    Department of Pathology, New York Presbyterian Hospital Weill Medical College of Cornell University NYPH WMC, New York 10021, USA
    Breast Cancer Res Treat 61:161-70. 2000
    ..We conclude that ILCs and well-differentiated IDCs show similar proliferation and cell cycle control antigen profiles. Despite their unusual histologic features, most ILC variants appear to maintain a characteristic ILC immunophenotype...
  53. ncbi request reprint Acidic fibroblast growth factor is expressed sequentially in the progression from Barrett's esophagus to esophageal adenocarcinoma
    R A Soslow
    Department of Pathology, New York Presbyterian Hospital Weill Medical College of Cornell University NYPH WMC, New York, NY 10021, USA
    Dis Esophagus 14:23-7. 2001
    ..The data also underscore the important role of fibroblast growth factors in tumorigenesis...
  54. ncbi request reprint h-Caldesmon, a novel smooth muscle-specific antibody, distinguishes between cellular leiomyoma and endometrial stromal sarcoma
    D S Rush
    Department of Pathology, Weill Medical College of Cornell University, New York, New York, USA
    Am J Surg Pathol 25:253-8. 2001
    ..We also report here that h-cal is useful more specifically in the differentiation of CL from ESS...
  55. ncbi request reprint Gastrointestinal adenocarcinoma arising in a mature cystic teratoma of the ovary
    Douglas A Levine
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Gynecol Oncol 94:597-9. 2004
    ..Though malignant transformation can occur from any of the embryonic germ layers, the most common malignancy arising in these otherwise benign tumors is squamous cell carcinoma...
  56. doi request reprint p53 overexpression in morphologically ambiguous endometrial carcinomas correlates with adverse clinical outcomes
    Karuna Garg
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Mod Pathol 23:80-92. 2010
    ....
  57. ncbi request reprint Lysophosphatidic acid acyltransferase-beta (LPAAT-beta) is highly expressed in advanced ovarian cancer and is associated with aggressive histology and poor survival
    Catherine S M Diefenbach
    Gynecologic Medical Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Cancer 107:1511-9. 2006
    ..The significance of tumor overexpression of LPAAT-beta was investigated in a large number of advanced- and early-stage EOC patients...
  58. ncbi request reprint Serous adenocarcinoma of the inguinal region arising from endometriosis followed by a successful pregnancy
    Brian M Slomovitz
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, NY 10021, USA
    Gynecol Oncol 87:152-4. 2002
    ..Inguinal serous carcinoma arising from endometriosis is an unusual cancer. It is uncertain how patients with these tumors should be managed, especially those patients who desire future fertility...
  59. ncbi request reprint Beta-catenin and E-cadherin expression patterns in high-grade endometrial carcinoma are associated with histological subtype
    Peter W Schlosshauer
    Department of Pathology, Weill Medical College of Cornell University, New York, New York, USA
    Mod Pathol 15:1032-7. 2002
    ..Notably, differences in cell adhesion molecule expression could account for variations in patterns of tumor dissemination. The immunohistochemical staining pattern may also be useful for diagnostic purposes...
  60. ncbi request reprint Apoptotic and cell cycle regulatory markers in uterine leiomyosarcoma
    Aliza L Leiser
    Developmental Chemotherapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Gynecol Oncol 101:86-91. 2006
    ..A secondary aim was to examine if the apoptotic and cell cycle regulatory protein expression profile of uterine leiomyosarcoma is potentially useful for clinical prognostic purposes...
  61. ncbi request reprint Difficulties in assessing the depth of myometrial invasion in endometrial carcinoma
    Asya Ali
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Int J Gynecol Pathol 26:115-23. 2007
    ..Measuring the DMI is usually uncomplicated, but additional scrutiny should be paid to cases involving exophytic tumors, irregular endomyometrial junctions, adenomyosis, and extensive stromal smooth muscle metaplasia...
  62. ncbi request reprint High frequency of JAZF1-JJAZ1 gene fusion in endometrial stromal tumors with smooth muscle differentiation by interphase FISH detection
    Esther Oliva
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Surg Pathol 31:1277-84. 2007
    ..Our results indicate that the detection of this chromosomal abnormality can be used to diagnose ESTs with smooth muscle differentiation when the smooth muscle component is predominant...
  63. ncbi request reprint Tumor promoting properties of the ETS protein MEF in ovarian cancer
    J J Yao
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Oncogene 26:4032-7. 2007
    ..MEF is an important regulator of the tumorigenic properties of ovarian cancer cells and could be used a therapeutic target in ovarian cancer...
  64. pmc A nomogram for predicting overall survival of women with endometrial cancer following primary therapy: toward improving individualized cancer care
    N R Abu-Rustum
    Department of Surgery, Gynecology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Gynecol Oncol 116:399-403. 2010
    ..Our objective was to develop a clinically useful nomogram in the hope of providing a more individualized and accurate estimation of overall survival (OS) following primary therapy...
  65. ncbi request reprint Lynch syndrome (hereditary non-polyposis colorectal cancer) and endometrial carcinoma
    K Garg
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York 10065, USA
    J Clin Pathol 62:679-84. 2009
    ..Consideration should be given to incorporating these screening criteria into a revision of the Bethesda guidelines for detecting EC patients at highest risk for HNPCC...
  66. doi request reprint Treatment of advanced uterine leiomyosarcoma with aromatase inhibitors
    Roisin O'Cearbhaill
    Department of Medicine, Gynecology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Gynecol Oncol 116:424-9. 2010
    ..Aromatase inhibitors are sometimes used in the treatment of selected patients with uterine leiomyosarcoma (LMS), but there are few data assessing the efficacy of aromatase inhibitors in this setting...
  67. ncbi request reprint Microsomal prostaglandin E synthase-1 is overexpressed in head and neck squamous cell carcinoma
    Erik G Cohen
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Clin Cancer Res 9:3425-30. 2003
    ..Additional studies will be needed to determine whether this enzyme is a bona fide target for anticancer therapy...
  68. ncbi request reprint Diagnostic Accuracy of Cervical Low-Grade Squamous Intraepithelial Lesions Is Improved With MIB-1 Immunostaining
    Edyta C Pirog
    Department of Pathology, Weill Medical College of Cornell University, New York, NY 10021, USA
    Am J Surg Pathol 26:70-5. 2002
    ..9) and the specificity (0.8) of HPV testing. In conclusion, MIB-1 is a highly sensitive and specific marker for identifying low-grade squamous intraepithelial lesion and is helpful in verifying the diagnosis of equivocal cases...
  69. ncbi request reprint Development of endometrial cancer after radiation treatment for cervical carcinoma
    Bhavana Pothuri
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Obstet Gynecol 101:941-5. 2003
    ..To detail the Memorial Sloan-Kettering Cancer Center and MD Anderson Cancer Center experience with 23 patients treated with radiation therapy for invasive cervical carcinoma who subsequently developed endometrial carcinoma...
  70. doi request reprint Clinicopathologic features of bone metastases and outcomes in patients with primary endometrial cancer
    Siobhan M Kehoe
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, United States
    Gynecol Oncol 117:229-33. 2010
    ..However, there have been reported cases of primary endometrial cancer with metastasis to the bone. The objective of this study was to describe the clinical and pathologic features of endometrial cancer metastatic to bone...
  71. ncbi request reprint Tissue microarray immunohistochemical expression of estrogen, progesterone, and androgen receptors in uterine leiomyomata and leiomyosarcoma
    Mario M Leitao
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Cancer 101:1455-62. 2004
    ..The authors also sought to assess the prognostic value of ER, PR, and AR expression in LMS...
  72. ncbi request reprint Comparison of uterine malignancies that develop during and following tamoxifen therapy
    Sarah E Ferguson
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Gynecol Oncol 101:322-6. 2006
    ....
  73. doi request reprint Ovarian mature teratomas with mucinous epithelial neoplasms: morphologic heterogeneity and association with pseudomyxoma peritonei
    Jesse K McKenney
    Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Am J Surg Pathol 32:645-55. 2008
    ..In contrast, teratomas with an invasive carcinomatous component and microscopic peritoneal carcinomatosis follow an aggressive clinical course...
  74. ncbi request reprint Molecular detection of JAZF1-JJAZ1 gene fusion in endometrial stromal neoplasms with classic and variant histology: evidence for genetic heterogeneity
    Hsuan Ying Huang
    Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Am J Surg Pathol 28:224-32. 2004
    ..Hence, the diagnostic utility of a JAZF1-JJAZ1 fusion transcript assay in ESTs may be limited to the classic histologic subset...
  75. ncbi request reprint Clinicopathologic features of rhabdomyosarcoma of gynecologic origin in adults
    Sarah E Ferguson
    Gynecology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 31:382-9. 2007
    ..It is unclear whether these divergent outcomes are the result of differences in clinical management or because these tumors are biologically distinct...
  76. ncbi request reprint Wilms Tumor Gene (WT1) and p53 expression in endometrial carcinomas: a study of 130 cases using a tissue microarray
    Jakob Dupont
    Developmental Chemotherapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Gynecol Oncol 94:449-55. 2004
    ..We studied a large number of endometrial carcinomas to determine the range of tumors that express WT1; this could have prognostic and therapeutic significance...
  77. pmc Stage-specific outcomes of patients with uterine leiomyosarcoma: a comparison of the international Federation of gynecology and obstetrics and american joint committee on cancer staging systems
    Oliver Zivanovic
    Department of Medicine, Gynecologic Medical Oncology Service, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA
    J Clin Oncol 27:2066-72. 2009
    ..We aimed to determine whether the American Joint Committee on Cancer (AJCC) soft tissue sarcoma (STS) staging system is more accurate in predicting progression-free survival (PFS) and overall survival (OS)...
  78. ncbi request reprint Serous borderline (low malignant potential, atypical proliferative) ovarian tumors: workshop perspectives
    Debra A Bell
    Department of Pathology, Massachusetts General Hospital, Boston 02114 2696, USA
    Hum Pathol 35:934-48. 2004
    ....
  79. ncbi request reprint p53, epidermal growth factor, and platelet-derived growth factor in uterine leiomyosarcoma and leiomyomas
    S E Anderson
    Department of Developmental Chemotherapy, Gynecology Disease Management Team, Memorial Sloan Kettering Cancer Center, New York, USA
    Int J Gynecol Cancer 16:849-53. 2006
    ..EGFR was not commonly expressed in ULMS. These uniquely expressed markers may assist in stratifying patients by survival and identify novel therapeutic markers. Clearly, further investigation is needed...
  80. doi request reprint Chromosomal instability in fallopian tube precursor lesions of serous carcinoma and frequent monoclonality of synchronous ovarian and fallopian tube mucosal serous carcinoma
    Shannon Salvador
    Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada
    Gynecol Oncol 110:408-17. 2008
    ..Recent studies suggest these cancers may arise in the fallopian tube. This study explores the relationship between ovarian cancers and fallopian tube mucosal involvement...
  81. doi request reprint Mixed ovarian epithelial carcinomas with clear cell and serous components are variants of high-grade serous carcinoma: an interobserver correlative and immunohistochemical study of 32 cases
    Guangming Han
    Department of Pathology and Laboratory Medicine, University of British Columbia and Vancouver General Hospital, Vancouver, BC, Canada
    Am J Surg Pathol 32:955-64. 2008
    ..3) Mixed SEC with clear cell and serous components show similar stage, mitotic activities, and immunoreactivities to those of pure SC, and likely represent SC with clear cell changes...
  82. ncbi request reprint Expression of epithelial membrane protein-2 is associated with endometrial adenocarcinoma of unfavorable outcome
    Madhuri Wadehra
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, California, USA
    Cancer 107:90-8. 2006
    ..These features suggest that EMP2 may contribute to neoplastic traits of endometrial cancer. The objective of this study was to determine the prevalence of EMP2 expression in endometrial neoplasms and its clinical significance...
  83. ncbi request reprint Immunoreactivity of p16 in anal cytology specimens: histologic correlation
    Farbod Darvishian
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer 108:66-71. 2006
    ..Due to potential diagnostic pitfalls in anal cytology, p16 overexpression in these specimens was studied...
  84. ncbi request reprint Recommendations for the reporting of fallopian tube neoplasms
    Teri A Longacre
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    Hum Pathol 38:1160-3. 2007
    ....
  85. ncbi request reprint Absence of Y chromosome in human placental site trophoblastic tumor
    Pei Hui
    Department of Pathology, Yale University, New Haven, CT 06520 8023, USA
    Mod Pathol 20:1055-60. 2007
    ....
  86. ncbi request reprint Clinicopathologic significance of defective DNA mismatch repair in endometrial carcinoma
    Destin Black
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Clin Oncol 24:1745-53. 2006
    ..The pathognomonic molecular manifestation of this repair defect is microsatellite instability (MSI). Here, we test the hypothesis that MSI predicts the clinicopathologic features of endometrial carcinoma...
  87. ncbi request reprint Routinely assessed morphological features correlate with microsatellite instability status in endometrial cancer
    Jinru Shia
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Hum Pathol 39:116-25. 2008
    ..Therefore, morphological patterns encountered in endometrial carcinoma may prove useful in screening tumors under consideration for MSI testing and identifying appropriate patients for referral to a genetic counseling service...
  88. ncbi request reprint Fallopian tube and primary peritoneal carcinomas associated with BRCA mutations
    Douglas A Levine
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Clin Oncol 21:4222-7. 2003
    ....
  89. ncbi request reprint Melan-A (A103) and inhibin expression in ovarian neoplasms
    Davis X Yao
    Department of Pathology, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, New York, U S A
    Appl Immunohistochem Mol Morphol 11:244-9. 2003
    ..Thus, adding A103 to a panel of markers including inhibin may be a valuable adjunct in the differential diagnoses of SCSTs and their distinction from other ovarian neoplasms...
  90. ncbi request reprint Mutation and expression of the TP53 gene in early stage epithelial ovarian carcinoma
    Mario M Leitao
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Gynecol Oncol 93:301-6. 2004
    ..The purpose of this study was to perform a comprehensive analysis of TP53 mutation and p53 expression status in early stage ovarian carcinomas...
  91. ncbi request reprint Borderline ovarian tumors: diverse contemporary viewpoints on terminology and diagnostic criteria with illustrative images
    Jeffrey D Seidman
    Department of Pathology, Washington Hospital Center, Washington DC 20010, USA
    Hum Pathol 35:918-33. 2004
    ..For those issues where there is disagreement, the terminology and diagnostic approaches reflecting the differing views are presented...
  92. ncbi request reprint Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease. Evidence for involvement of the transcription factor Egr-1
    Kotha Subbaramaiah
    Department of Medicine, New York Presbyterian Hospital, Weill Medical College of Cornell University and Strang Cancer Prevention Center, 1300 York Avenue, Room F 203A, New York, NY 10021, USA
    J Biol Chem 279:12647-58. 2004
    ..Moreover, TNF-alpha induced mPGES-1 by stimulating PC-PLC --> PKC --> NO --> cGMP --> PKG signal transduction pathway...