Roy V Sillitoe

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. ncbi request reprint Morphology, molecular codes, and circuitry produce the three-dimensional complexity of the cerebellum
    Roy V Sillitoe
    Developmental Biology Program, Sloan Kettering Institute, New York, NY 10021, USA
    Annu Rev Cell Dev Biol 23:549-77. 2007
  2. pmc Engrailed homeobox genes regulate establishment of the cerebellar afferent circuit map
    Roy V Sillitoe
    Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10021, USA
    J Neurosci 30:10015-24. 2010
  3. pmc Axon sorting within the spinal cord marginal zone via Robo-mediated inhibition of N-cadherin controls spinocerebellar tract formation
    Nozomi Sakai
    Dominick P Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, 10461, USA
    J Neurosci 32:15377-87. 2012
  4. pmc Engrailed homeobox genes determine the organization of Purkinje cell sagittal stripe gene expression in the adult cerebellum
    Roy V Sillitoe
    Developmental Biology Program, Sloan Kettering Institute, New York, New York 10021, USA
    J Neurosci 28:12150-62. 2008
  5. doi request reprint Golgi cell dendrites are restricted by Purkinje cell stripe boundaries in the adult mouse cerebellar cortex
    Roy V Sillitoe
    Department of Cell Biology and Anatomy, Genes and Development Research Group, and Hotchkiss Brain Institute, Faculty of Medicine, The University of Calgary, Calgary, Alberta, Canada
    J Neurosci 28:2820-6. 2008
  6. ncbi request reprint Conservation of the architecture of the anterior lobe vermis of the cerebellum across mammalian species
    Roy V Sillitoe
    Department of Cell Biology and Anatomy, and Genes and Development Research Group, Faculty of Medicine, The University of Calgary, 3330 Hospital Drive N W, Calgary, AB T2N 4N1, Canada
    Prog Brain Res 148:283-97. 2005
  7. ncbi request reprint Abnormal HNK-1 expression in the cerebellum of an N-CAM null mouse
    Hassan Marzban
    Department of Cell Biology and Anatomy, and Genes and Development Research Group, Faculty of Medicine, The University of Calgary, Calgary, Alberta T2N 4N1, Canada
    J Neurocytol 33:117-30. 2004
  8. pmc Antigenic compartmentation of the primate and tree shrew cerebellum: a common topography of zebrin II in Macaca mulatta and Tupaia belangeri
    Roy V Sillitoe
    Department of Cell Biology and Anatomy, and Genes and Development Research Group, Faculty of Medicine, The University of Calgary, Alberta, Canada
    J Anat 204:257-69. 2004
  9. pmc Zebrin II compartmentation of the cerebellum in a basal insectivore, the Madagascan hedgehog tenrec Echinops telfairi
    Roy V Sillitoe
    Department of Cell Biology and Anatomy, and Genes and Development Research Group, Faculty of Medicine, The University of Calgary, Alberta, Canada
    J Anat 203:283-96. 2003
  10. ncbi request reprint Abnormal dysbindin expression in cerebellar mossy fiber synapses in the mdx mouse model of Duchenne muscular dystrophy
    Roy V Sillitoe
    Department of Cell Biology and Anatomy, and Genes and Development Research Group, Faculty of Medicine, The University of Calgary, Calgary, Alberta T2N 4N1, Canada
    J Neurosci 23:6576-85. 2003

Collaborators

  • A L Joyner
  • Michael W Vogel
  • J M Fritschy
  • Richard Hawkes
  • Nozomi Sakai
  • Hassan Marzban
  • Matt Larouche
  • Justyna R Sarna
  • Miguel Sanchez
  • Zaven Kaprielian
  • Ryan Insolera
  • Song Hai Shi
  • Seung Hyuk Chung
  • Monica Hoy
  • Victor F Rafuse
  • Derrick E Rancourt
  • Chi Diep
  • Magnus Ivarsson
  • Christopher H Yeo
  • Philip J E Attwell
  • Shbana Rahman

Detail Information

Publications15

  1. ncbi request reprint Morphology, molecular codes, and circuitry produce the three-dimensional complexity of the cerebellum
    Roy V Sillitoe
    Developmental Biology Program, Sloan Kettering Institute, New York, NY 10021, USA
    Annu Rev Cell Dev Biol 23:549-77. 2007
    ..Finally, we discuss how abnormal cerebellar organization may result in neurological disorders like autism...
  2. pmc Engrailed homeobox genes regulate establishment of the cerebellar afferent circuit map
    Roy V Sillitoe
    Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10021, USA
    J Neurosci 30:10015-24. 2010
    ..In summary, our data suggest that En1/2 are master regulators of three-dimensional organization of the cerebellum and coordinately regulate morphology, patterned gene expression, and afferent topography...
  3. pmc Axon sorting within the spinal cord marginal zone via Robo-mediated inhibition of N-cadherin controls spinocerebellar tract formation
    Nozomi Sakai
    Dominick P Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, 10461, USA
    J Neurosci 32:15377-87. 2012
    ..Together, these findings suggest that spinal projection axons must be sorted into distinct longitudinal tracts within the spinal cord proper to project to their brain targets...
  4. pmc Engrailed homeobox genes determine the organization of Purkinje cell sagittal stripe gene expression in the adult cerebellum
    Roy V Sillitoe
    Developmental Biology Program, Sloan Kettering Institute, New York, New York 10021, USA
    J Neurosci 28:12150-62. 2008
    ..Our studies reveal that En1/2 are fundamental components of the genetic pathways that pattern the two intersecting coordinate systems of the Cb, morphological divisions and the molecular code...
  5. doi request reprint Golgi cell dendrites are restricted by Purkinje cell stripe boundaries in the adult mouse cerebellar cortex
    Roy V Sillitoe
    Department of Cell Biology and Anatomy, Genes and Development Research Group, and Hotchkiss Brain Institute, Faculty of Medicine, The University of Calgary, Calgary, Alberta, Canada
    J Neurosci 28:2820-6. 2008
    ..The data presented here show that the dendrites of a cerebellar interneuron, the Golgi cell, respect the fundamental cerebellar stripe cytoarchitecture...
  6. ncbi request reprint Conservation of the architecture of the anterior lobe vermis of the cerebellum across mammalian species
    Roy V Sillitoe
    Department of Cell Biology and Anatomy, and Genes and Development Research Group, Faculty of Medicine, The University of Calgary, 3330 Hospital Drive N W, Calgary, AB T2N 4N1, Canada
    Prog Brain Res 148:283-97. 2005
  7. ncbi request reprint Abnormal HNK-1 expression in the cerebellum of an N-CAM null mouse
    Hassan Marzban
    Department of Cell Biology and Anatomy, and Genes and Development Research Group, Faculty of Medicine, The University of Calgary, Calgary, Alberta T2N 4N1, Canada
    J Neurocytol 33:117-30. 2004
    ..Despite the absence of N-CAM/HNK-1, parasagittal stripes and transverse zones in the cerebellum as revealed by using zebrin II immunocytochemistry appear normal...
  8. pmc Antigenic compartmentation of the primate and tree shrew cerebellum: a common topography of zebrin II in Macaca mulatta and Tupaia belangeri
    Roy V Sillitoe
    Department of Cell Biology and Anatomy, and Genes and Development Research Group, Faculty of Medicine, The University of Calgary, Alberta, Canada
    J Anat 204:257-69. 2004
    ..The data suggest that cerebellar compartmentation in Tupaia belangeri more closely resembles that of primates than it does rodents or lagomorphs...
  9. pmc Zebrin II compartmentation of the cerebellum in a basal insectivore, the Madagascan hedgehog tenrec Echinops telfairi
    Roy V Sillitoe
    Department of Cell Biology and Anatomy, and Genes and Development Research Group, Faculty of Medicine, The University of Calgary, Alberta, Canada
    J Anat 203:283-96. 2003
    ..We conclude that a zone-and-stripe organization may be a common feature of the mammalian cerebellar vermis and hemispheres, and that zonal boundaries and cerebellar lobules and fissures form independently...
  10. ncbi request reprint Abnormal dysbindin expression in cerebellar mossy fiber synapses in the mdx mouse model of Duchenne muscular dystrophy
    Roy V Sillitoe
    Department of Cell Biology and Anatomy, and Genes and Development Research Group, Faculty of Medicine, The University of Calgary, Calgary, Alberta T2N 4N1, Canada
    J Neurosci 23:6576-85. 2003
    ..Abnormal synaptic organization in the cerebellum may contribute to the neurological problems associated with muscular dystrophy and schizophrenia...
  11. ncbi request reprint Antigenic compartmentation of the cat cerebellar cortex
    Roy V Sillitoe
    Department of Cell Biology and Anatomy, Genes and Development Research Group, Faculty of Medicine, The University of Calgary, 3330 Hospital Drive N W, Calgary, Alberta T2N 4N1, Canada
    Brain Res 977:1-15. 2003
    ....
  12. ncbi request reprint Topographical anatomy of the cerebellum in the guinea pig, Cavia porcellus
    Matt Larouche
    Department of Cell Biology and Anatomy, Faculty of Medicine, University of Calgary, 3330 Hospital Drive N W, Alberta, Calgary, Canada T2N 4N1
    Brain Res 965:159-69. 2003
    ....
  13. ncbi request reprint Patterned Purkinje cell degeneration in mouse models of Niemann-Pick type C disease
    Justyna R Sarna
    Department of Cell Biology and Anatomy, and Genes and Development Research Group, Faculty of Medicine, The University of Calgary, Alberta T2N 4N1, Canada
    J Comp Neurol 456:279-91. 2003
    ..The pattern of cell death thus reflects the fundamental compartmentation of the cerebellum into zones and stripes...
  14. ncbi request reprint Compartmentation of the rabbit cerebellar cortex
    Miguel Sanchez
    Department of Cell Biology and Anatomy, and Genes and Development Research Group, Faculty of Medicine, The University of Calgary, Calgary, Alberta T2N 4N1, Canada
    J Comp Neurol 444:159-73. 2002
    ..Thus, the organization of the rabbit cerebellum is consistent with the patterns described previously for rat, mouse, and opossum and suggests that there may be a common ground plan for the mammalian cerebellum...
  15. ncbi request reprint Whole-mount immunohistochemistry: a high-throughput screen for patterning defects in the mouse cerebellum
    Roy V Sillitoe
    Department of Cell Biology and Anatomy, and Genes and Development Research Group, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Histochem Cytochem 50:235-44. 2002
    ..By use of this approach, normal adult murine cerebellar topography and patterning defects caused by mutation can be studied without the need for three-dimensional reconstruction...