Jaya M Satagopan

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. ncbi request reprint Ovarian cancer risk in Ashkenazi Jewish carriers of BRCA1 and BRCA2 mutations
    Jaya M Satagopan
    Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Clin Cancer Res 8:3776-81. 2002
  2. ncbi request reprint Frequency of BRCA1 and BRCA2 mutations in unselected Ashkenazi Jewish patients with colorectal cancer
    Tomas Kirchhoff
    Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Natl Cancer Inst 96:68-70. 2004
  3. ncbi request reprint BRCA1 and BRCA2 germline mutations in lymphoma patients
    Orit Yossepowitch
    Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Leuk Lymphoma 44:127-31. 2003
  4. ncbi request reprint Risk-reducing salpingo-oophorectomy in women with a BRCA1 or BRCA2 mutation
    Noah D Kauff
    Clinical Genetics Service, Memorial Sloan Kettering Cancer Center, New York 10021, USA
    N Engl J Med 346:1609-15. 2002
  5. pmc Prospective study of sunburn and sun behavior patterns during adolescence
    Stephen W Dusza
    Department of Medicine, Memorial Sloan Kettering Cancer Center, Dermatology Service, New York, NY 10022, USA
    Pediatrics 129:309-17. 2012
  6. pmc TMPRSS2-ERG gene fusion is associated with low Gleason scores and not with high-grade morphological features
    Samson W Fine
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Mod Pathol 23:1325-33. 2010
  7. pmc Clinical and dermoscopic stability and volatility of melanocytic nevi in a population-based cohort of children in Framingham school system
    Alon Scope
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, New York 10022, USA
    J Invest Dermatol 131:1615-21. 2011
  8. pmc Variants in activators and downstream targets of ATM, radiation exposure, and contralateral breast cancer risk in the WECARE study
    Jennifer D Brooks
    Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Hum Mutat 33:158-64. 2012
  9. ncbi request reprint Two-stage designs for gene-disease association studies with sample size constraints
    Jaya M Satagopan
    Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Biometrics 60:589-97. 2004
  10. pmc Evaluation of removable statistical interaction for binary traits
    Jaya M Satagopan
    Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Stat Med 32:1164-90. 2013

Detail Information

Publications25

  1. ncbi request reprint Ovarian cancer risk in Ashkenazi Jewish carriers of BRCA1 and BRCA2 mutations
    Jaya M Satagopan
    Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Clin Cancer Res 8:3776-81. 2002
    ..To address this, we have used a case-control design that does not involve familial aggregation to estimate the lifetime penetrance of ovarian cancer due to BRCA1 and BRCA2 mutations...
  2. ncbi request reprint Frequency of BRCA1 and BRCA2 mutations in unselected Ashkenazi Jewish patients with colorectal cancer
    Tomas Kirchhoff
    Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Natl Cancer Inst 96:68-70. 2004
    ..22 to 1.14). We thus recommend that counseling for colorectal cancer screening and prevention in individuals with BRCA mutations be based on the personal and family history of colorectal cancer or associated syndromic malignancies...
  3. ncbi request reprint BRCA1 and BRCA2 germline mutations in lymphoma patients
    Orit Yossepowitch
    Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Leuk Lymphoma 44:127-31. 2003
    ..This data indicate that germline BRCA mutations are not associated with an increased risk for lymphoid malignancies...
  4. ncbi request reprint Risk-reducing salpingo-oophorectomy in women with a BRCA1 or BRCA2 mutation
    Noah D Kauff
    Clinical Genetics Service, Memorial Sloan Kettering Cancer Center, New York 10021, USA
    N Engl J Med 346:1609-15. 2002
    ..We prospectively compared the effect of risk-reducing salpingo-oophorectomy with that of surveillance for ovarian cancer on the incidence of subsequent breast cancer and BRCA-related gynecologic cancers in women with BRCA mutations...
  5. pmc Prospective study of sunburn and sun behavior patterns during adolescence
    Stephen W Dusza
    Department of Medicine, Memorial Sloan Kettering Cancer Center, Dermatology Service, New York, NY 10022, USA
    Pediatrics 129:309-17. 2012
    ..Early childhood UV light radiation (UVR) exposures have been shown to be associated with melanoma development later in life. The objective of this study was to assess sunburn and changes in sunburn and sun behaviors during periadolescence...
  6. pmc TMPRSS2-ERG gene fusion is associated with low Gleason scores and not with high-grade morphological features
    Samson W Fine
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Mod Pathol 23:1325-33. 2010
    ..These findings indicate that translocation/deletion of TMPRSS2-ERG is not associated with histological features of aggressive prostate cancer...
  7. pmc Clinical and dermoscopic stability and volatility of melanocytic nevi in a population-based cohort of children in Framingham school system
    Alon Scope
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, New York 10022, USA
    J Invest Dermatol 131:1615-21. 2011
    ..In conclusion, the relative stability of dermoscopic pattern of individual nevi in the face of the overall volatility of nevi during adolescence suggests that specific dermoscopic patterns may represent distinct biological nevus subsets...
  8. pmc Variants in activators and downstream targets of ATM, radiation exposure, and contralateral breast cancer risk in the WECARE study
    Jennifer D Brooks
    Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Hum Mutat 33:158-64. 2012
    ..This suggests that carriers of this haplotype may be susceptible to the DNA-damaging effects of radiation therapy associated with radiation-induced breast cancer...
  9. ncbi request reprint Two-stage designs for gene-disease association studies with sample size constraints
    Jaya M Satagopan
    Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Biometrics 60:589-97. 2004
    ....
  10. pmc Evaluation of removable statistical interaction for binary traits
    Jaya M Satagopan
    Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Stat Med 32:1164-90. 2013
    ..We illustrate the proposed test and use of the transformation by using case-control data from three published studies. Finally, we indicate how one can check that, after transformation, no further interaction is significant...
  11. pmc Study of Nevi in Children (SONIC): baseline findings and predictors of nevus count
    Susan A Oliveria
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10022, USA
    Am J Epidemiol 169:41-53. 2009
    ..041), and often and always (RR = 1.32, 95% CI: 1.13, 1.54; P = 0.001) were associated with increased number of nevi. Identifying factors that predict the development of nevi will improve primary prevention efforts during early life...
  12. pmc Copy number and gene expression differences between African American and Caucasian American prostate cancer
    Amy E Rose
    Department of Urology, New York University School of Medicine, New York, New York 10016, USA
    J Transl Med 8:70. 2010
    ....
  13. pmc Normalization method for transcriptional studies of heterogeneous samples--simultaneous array normalization and identification of equivalent expression
    Li Xuan Qin
    Memorial Sloan Kettering Cancer Center
    Stat Appl Genet Mol Biol 8:Article 10. 2009
    ..Empirical illustration of the proposed method is provided using a liposarcoma study from MSKCC to identify genes differentially expressed between normal fat tissue versus liposarcoma tissue samples...
  14. ncbi request reprint A statistical perspective on gene expression data analysis
    Jaya M Satagopan
    Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Stat Med 22:481-99. 2003
    ..S-plus and SAS codes to perform the statistical methods are provided. Gene expression data from an unpublished oncologic study is used to illustrate these methods...
  15. ncbi request reprint Sequential quantitative trait locus mapping in experimental crosses
    Jaya M Satagopan
    Memorial Sloan Kettering Cancer Center, USA
    Stat Appl Genet Mol Biol 6:Article12. 2007
    ..We examine settings under which the two-stage analytic approach provides sufficient power to detect the putative QTLs...
  16. ncbi request reprint Rare variants of ATM and risk for Hodgkin's disease and radiation-associated breast cancers
    Kenneth Offit
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Clin Cancer Res 8:3813-9. 2002
    ..We next sought to determine the frequency of ATM variants in patients with Hodgkin's lymphoma, regardless of coexisting BC, compared with healthy volunteers...
  17. pmc Allergies and risk of pancreatic cancer: a pooled analysis from the Pancreatic Cancer Case-Control Consortium
    Sara H Olson
    Department of Epidemiology and Biostatistics, 307 East 63rd Street, New York, NY 10065, USA
    Am J Epidemiol 178:691-700. 2013
    ..There were no major differences among subgroups defined by age, gender, smoking status, or body mass index. Older age at onset of allergies was slightly more protective than earlier age. ..
  18. pmc TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy
    Anuradha Gopalan
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Cancer Res 69:1400-6. 2009
    ....
  19. ncbi request reprint Two-stage designs for gene-disease association studies
    Jaya M Satagopan
    Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Biometrics 58:163-70. 2002
    ..This translates to screening all the markers on approximately one quarter of the required sample size in stage 1...
  20. ncbi request reprint Novel mutations of epidermal growth factor receptor in localized prostate cancer
    Diah A Douglas
    Department of Urology, New York University School of Medicine, New York, NY 10016, USA
    Front Biosci 11:2518-25. 2006
    ..Larger population-based studies are required to define the association between EGFR mutations and the ethnic background of patients...
  21. ncbi request reprint Optimal two-stage genotyping in population-based association studies
    Jaya M Satagopan
    Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Genet Epidemiol 25:149-57. 2003
    ..The results show that, compared to a one-stage approach, a two-stage procedure typically halves the cost of the study...
  22. ncbi request reprint Age-adjusted International Prognostic Index predicts autologous stem cell transplantation outcome for patients with relapsed or primary refractory diffuse large B-cell lymphoma
    Paul A Hamlin
    Lymphoma and Hematology Services, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Box 350, 1275 York Ave, New York, NY, 10021
    Blood 102:1989-96. 2003
    ..This powerful prognostic instrument should be used to evaluate new treatment approaches and to compare results of different regimens...
  23. pmc Genetic heterogeneity among Fanconi anemia heterozygotes and risk of cancer
    Marianne Berwick
    Cancer Research and Treatment Center Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA
    Cancer Res 67:9591-6. 2007
    ..4; 95% CI, 1.1-5.2). Overall, there was no increased risk for cancer among FA heterozygotes in this study of Fanconi relatives, although there is some evidence that FANCC mutations are possibly breast cancer susceptibility alleles...
  24. pmc Quantitative trait locus study design from an information perspective
    Saunak Sen
    Department of Epidemiology and Biostatistics, University of California, San Francisco, 94143, USA
    Genetics 170:447-64. 2005
    ..Software for performing power calculations for backcross and F(2) intercross incorporating selective genotyping and marker spacing is available from http://www.biostat.ucsf.edu/sen...
  25. pmc R/qtlDesign: inbred line cross experimental design
    Saunak Sen
    Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California 94143, USA
    Mamm Genome 18:87-93. 2007
    ..We give examples of software usage in real-life settings. The software is available at http://www.biostat.ucsf.edu/sen/software.html ...