V W Rusch

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. doi request reprint Initial analysis of the international association for the study of lung cancer mesothelioma database
    Valerie W Rusch
    Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Thorac Oncol 7:1631-9. 2012
  2. ncbi request reprint Management of Pancoast tumours
    Valerie W Rusch
    Thoracic Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Lancet Oncol 7:997-1005. 2006
  3. ncbi request reprint Surgery for bronchioloalveolar carcinoma and "very early" adenocarcinoma: an evolving standard of care?
    Valerie W Rusch
    Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Oncol 1:S27-31. 2006
  4. ncbi request reprint The IASLC Lung Cancer Staging Project: proposals for the revision of the N descriptors in the forthcoming seventh edition of the TNM classification for lung cancer
    Valerie W Rusch
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Oncol 2:603-12. 2007
  5. doi request reprint The IASLC lung cancer staging project: a proposal for a new international lymph node map in the forthcoming seventh edition of the TNM classification for lung cancer
    Valerie W Rusch
    Thoracic Surgery Service, Memorial Sloan Kettering Cancer Center, New York City, New York 10065, USA
    J Thorac Oncol 4:568-77. 2009
  6. doi request reprint Nael Martini: a leader in thoracic surgical oncology
    Valerie W Rusch
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Ann Thorac Surg 89:1006-9. 2010
  7. ncbi request reprint A phase II trial of surgical resection and adjuvant high-dose hemithoracic radiation for malignant pleural mesothelioma
    V W Rusch
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 122:788-95. 2001
  8. pmc Occult metastases in lymph nodes predict survival in resectable non-small-cell lung cancer: report of the ACOSOG Z0040 trial
    Valerie W Rusch
    Thoracic Surgery Service, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA
    J Clin Oncol 29:4313-9. 2011
  9. ncbi request reprint The epidermal growth factor receptor and its ligands as therapeutic targets in human tumors
    V Rusch
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Cytokine Growth Factor Rev 7:133-41. 1996
  10. ncbi request reprint Indications for pneumonectomy. Extrapleural pneumonectomy
    V W Rusch
    Thoracic Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Chest Surg Clin N Am 9:327-38, x. 1999

Detail Information

Publications100

  1. doi request reprint Initial analysis of the international association for the study of lung cancer mesothelioma database
    Valerie W Rusch
    Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Thorac Oncol 7:1631-9. 2012
    ..To plan revisions of this system, the International Association for the Study of Lung Cancer Staging Committee developed an international database. Initial analyses focus on patients managed surgically...
  2. ncbi request reprint Management of Pancoast tumours
    Valerie W Rusch
    Thoracic Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Lancet Oncol 7:997-1005. 2006
    ..This review includes discussion of anatomical considerations, initial assessment, multimodality treatment, and surgical approaches for these cancers...
  3. ncbi request reprint Surgery for bronchioloalveolar carcinoma and "very early" adenocarcinoma: an evolving standard of care?
    Valerie W Rusch
    Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Oncol 1:S27-31. 2006
    ..To improve our management of very early AC, much more information is needed about the molecular abnormalities of AC and their relationship to clinical outcomes...
  4. ncbi request reprint The IASLC Lung Cancer Staging Project: proposals for the revision of the N descriptors in the forthcoming seventh edition of the TNM classification for lung cancer
    Valerie W Rusch
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Oncol 2:603-12. 2007
    ..We sought to determine whether the current N descriptors should be maintained or revised for the next edition of the international lung cancer staging system...
  5. doi request reprint The IASLC lung cancer staging project: a proposal for a new international lymph node map in the forthcoming seventh edition of the TNM classification for lung cancer
    Valerie W Rusch
    Thoracic Surgery Service, Memorial Sloan Kettering Cancer Center, New York City, New York 10065, USA
    J Thorac Oncol 4:568-77. 2009
    ..A method of grouping lymph node stations together into "zones" is also proposed for the purposes of future survival analyses...
  6. doi request reprint Nael Martini: a leader in thoracic surgical oncology
    Valerie W Rusch
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Ann Thorac Surg 89:1006-9. 2010
    ..Nael Martini was one of the leading academic general thoracic surgeons of the late 20th century. His most notable contributions related to the surgical and multimodality treatment of lung cancer...
  7. ncbi request reprint A phase II trial of surgical resection and adjuvant high-dose hemithoracic radiation for malignant pleural mesothelioma
    V W Rusch
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 122:788-95. 2001
    ..We performed a phase II trial of high-dose hemithoracic radiation after complete resection to determine feasibility and to estimate rates of local recurrence and survival...
  8. pmc Occult metastases in lymph nodes predict survival in resectable non-small-cell lung cancer: report of the ACOSOG Z0040 trial
    Valerie W Rusch
    Thoracic Surgery Service, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA
    J Clin Oncol 29:4313-9. 2011
    ..We investigated the prevalence of OMs in resectable NSCLC and their relationship with survival...
  9. ncbi request reprint The epidermal growth factor receptor and its ligands as therapeutic targets in human tumors
    V Rusch
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Cytokine Growth Factor Rev 7:133-41. 1996
    ....
  10. ncbi request reprint Indications for pneumonectomy. Extrapleural pneumonectomy
    V W Rusch
    Thoracic Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Chest Surg Clin N Am 9:327-38, x. 1999
    ..The potential role of extrapleural pneumonectomy in MPM is best considered in this context...
  11. ncbi request reprint Factors determining outcome after surgical resection of T3 and T4 lung cancers of the superior sulcus
    V W Rusch
    Thoracic Surgery, Orthopedic Surgery, and Neurosurgery Services, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Thorac Cardiovasc Surg 119:1147-53. 2000
    ..To establish a historical benchmark against which new therapies can be assessed, we reviewed our 24-year experience with patients undergoing thoracotomy for lung cancers of the superior sulcus...
  12. ncbi request reprint Important prognostic factors in patients with malignant pleural mesothelioma, managed surgically
    V W Rusch
    Department of Surgery, and Biostatistics Service, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 68:1799-804. 1999
    ..The factors influencing outcome after resection of malignant pleural mesothelioma (MPM) are controversial. This analysis of a prospective surgical database identifies important prognostic factors...
  13. ncbi request reprint Morbidity and mortality after neoadjuvant therapy for lung cancer: the risks of right pneumonectomy
    J Martin
    Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 72:1149-54. 2001
    ..However, right pneumonectomy is associated with a significantly increased risk and should be performed only in selected patients...
  14. ncbi request reprint Feasibility of multimodality therapy including extended resections in stage IVA thymoma
    James Huang
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Thorac Cardiovasc Surg 134:1477-83; discussion 1483-4. 2007
    ..We reviewed our experience with multimodality treatment for Masaoka stage IVA thymomas for feasibility and outcomes...
  15. ncbi request reprint Incidence and risk factors for lung injury after lung cancer resection
    Naveed Alam
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 84:1085-91; discussion 1091. 2007
    ..Our objective was to identify the incidence and risk factors for the development of postoperative lung injury...
  16. doi request reprint The IASLC Lung Cancer Staging Project: proposals for the inclusion of broncho-pulmonary carcinoid tumors in the forthcoming (seventh) edition of the TNM Classification for Lung Cancer
    William D Travis
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Oncol 3:1213-23. 2008
    ....
  17. ncbi request reprint Extent of chest wall invasion and survival in patients with lung cancer
    R J Downey
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 68:188-93. 1999
    ....
  18. ncbi request reprint Epidermal growth factor receptor signaling in adenocarcinomas with bronchioloalveolar components
    Inderpal S Sarkaria
    Laboratory of Epithelial Cancer Biology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 85:216-23. 2008
    ..This study assesses EGFR signaling in these tumors...
  19. ncbi request reprint Use of video-assisted thoracic surgery for lobectomy in the elderly results in fewer complications
    Stephen M Cattaneo
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 85:231-5; discussion 235-6. 2008
    ....
  20. ncbi request reprint Successful treatment of esophageal cancer with airway invasion with induction chemotherapy and concurrent chemoradiotherapy
    Geoffrey Y Ku
    Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Thorac Oncol 4:432-4. 2009
    ..Such a staged approach may reduce the morbidity of upfront radiation. The use of an interim positron emission tomography scan may also identify early treatment failure...
  21. doi request reprint Post-treatment endoscopic biopsy is a poor-predictor of pathologic response in patients undergoing chemoradiation therapy for esophageal cancer
    Inderpal S Sarkaria
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Ann Surg 249:764-7. 2009
    ..We wanted to determine if endoscopic biopsy can accurately establish evidence of local pathologic complete response (pCR) in patients undergoing CRT...
  22. ncbi request reprint Resection of superior sulcus tumors (posterior approach)
    Michael S Kent
    Thoracic Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center 1275 York Avenue, New York, USA
    Thorac Surg Clin 14:217-28. 2004
    ..Involvement of the vertebral body or brachial plexus, areas once considered unresectable, is amenable to advanced techniques of spinal reconstruction and may lead to long-term survival in selected patients...
  23. ncbi request reprint Long-term results of combined-modality therapy in resectable non-small-cell lung cancer
    Jocelyne Martin
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Clin Oncol 20:1989-95. 2002
    ..Assessment of long-term results of combined-modality therapy for resectable non-small-cell lung cancer is hampered by insufficient follow-up and small patient numbers. To evaluate this, we reviewed our collective experience...
  24. ncbi request reprint Lymphadenectomy for adenocarcinoma of the gastroesophageal junction (GEJ): impact of adequate staging on outcome
    Andrew P Barbour
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Ann Surg Oncol 14:306-16. 2007
    ..The aim of this study was to determine whether adequate staging revealed different prognostic factors or improved survival compared with patients with <15 nodes examined after R0 resection for GEJ cancer...
  25. ncbi request reprint Tension pneumocephalus resulting from iatrogenic subarachnoid-pleural fistulae: report of three cases
    M H Bilsky
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 71:455-7. 2001
    ..Symptomatic pneumocephalus may result from a cerebrospinal fluid leak communicating with extradural air. However, it is a rare event after thoracic surgical procedures, and its management and physiology are not widely recognized...
  26. ncbi request reprint Hemithoracic radiation therapy after pleurectomy/decortication for malignant pleural mesothelioma
    Vishal Gupta
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Int J Radiat Oncol Biol Phys 63:1045-52. 2005
    ..To evaluate pleurectomy/decortication (P/D) and adjuvant radiotherapy (RT) in the treatment of malignant pleural mesothelioma (MPM)...
  27. ncbi request reprint Clinical pattern and pathologic stage but not histologic features predict outcome for bronchioloalveolar carcinoma
    Michael I Ebright
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 74:1640-6; discussion 1646-7. 2002
    ..This study determined the outcome of resected BAC in relationship to clinical and radiologic disease pattern, and pathologic features...
  28. doi request reprint Prognostic and therapeutic implications of EGFR and KRAS mutations in resected lung adenocarcinoma
    Jenifer L Marks
    Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Oncol 3:111-6. 2008
    ..Whether EGFR and KRAS mutations also have an impact on survival in patients who undergo lung resection for curative intent in the absence of targeted therapy has not been established...
  29. doi request reprint Optimum lymphadenectomy for esophageal cancer
    Nabil P Rizk
    Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Surg 251:46-50. 2010
    ..Using Worldwide Esophageal Cancer Collaboration data, we sought to (1) characterize the relationship between survival and extent of lymphadenectomy, and (2) from this, define optimum lymphadenectomy...
  30. ncbi request reprint Surgical techniques for nonseminomatous germ cell tumors metastatic to the lung
    Daniel J Boffa
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Chest Surg Clin N Am 12:739-48. 2002
    ....
  31. ncbi request reprint The impact of complications on outcomes after resection for esophageal and gastroesophageal junction carcinoma
    Nabil P Rizk
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Am Coll Surg 198:42-50. 2004
    ..Strategies to optimize surgical technique have been less well studied. We sought to assess the relation between complications related to surgical technique and outcomes after esophagogastrectomy for cancer...
  32. doi request reprint Predictors of outcomes after surgical treatment of synchronous primary lung cancers
    David J Finley
    Department of Surgery, Thoracic Service, Memorial Sloan Kettering Cancer Center, New York City, New York 10021, USA
    J Thorac Oncol 5:197-205. 2010
    ..Determining this distinction with certainty, however, is challenging. We reviewed our experience with surgical resection of presumed SPLC to analyze outcomes and identify factors associated with prolonged survival...
  33. ncbi request reprint A grading system of lung adenocarcinomas based on histologic pattern is predictive of disease recurrence in stage I tumors
    Gabriel Sica
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Surg Pathol 34:1155-62. 2010
    ..65 (95% confidence interval 0.57-0.73). Therefore, this scoring system provides valuable information in discriminating patients with different risk of disease-recurrence in a highly homogeneous population of patients with stage I cancer...
  34. ncbi request reprint Effects of diltiazem prophylaxis on the incidence and clinical outcome of atrial arrhythmias after thoracic surgery
    D Amar
    Departments of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 120:790-8. 2000
    ..We sought to determine whether early prophylaxis with an L -type calcium channel blocker reduces the incidence and morbidity associated with atrial fibrillation/flutter and supraventricular tachyarrhythmia after major thoracic operations...
  35. ncbi request reprint Induction chemoradiation and surgical resection for non-small cell lung carcinomas of the superior sulcus: Initial results of Southwest Oncology Group Trial 9416 (Intergroup Trial 0160)
    V W Rusch
    Thoracic Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
    J Thorac Cardiovasc Surg 121:472-83. 2001
    ....
  36. ncbi request reprint Postoperative fluorescence bronchoscopic surveillance in non-small cell lung cancer patients
    T L Weigel
    Thoracic Surgery Service, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 71:967-70. 2001
    ..Fluorescence bronchoscopy appears to be a sensitive tool for surveillance of the tracheobronchial tree for early neoplasias...
  37. ncbi request reprint Small-cell carcinoma of the esophagus and gastroesophageal junction: review of the Memorial Sloan-Kettering experience
    G Y Ku
    Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Ann Oncol 19:533-7. 2008
    ..Esophageal small-cell carcinoma (SCC) is rare, highly malignant and the optimal treatment approach has not been defined...
  38. doi request reprint Insulin-like growth factor-1 receptor expression in thymic malignancies
    Nicolas Girard
    Human Oncology and Pathogenesis Program, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York City, NY 10065, USA
    J Thorac Oncol 5:1439-46. 2010
    ..As higher levels of IGF-1R protein expression may be associated with relative sensitivity to anti-IGF-1R antibody treatment, we investigated IGF-1R expression in thymic malignancies...
  39. ncbi request reprint Use of cigarette-smoking history to estimate the likelihood of mutations in epidermal growth factor receptor gene exons 19 and 21 in lung adenocarcinomas
    DuyKhanh Pham
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Clin Oncol 24:1700-4. 2006
    ..Investigators have reported an association between EGFR mutations and the amount and duration of cigarette smoking, with the highest incidence of mutations seen in never smokers...
  40. pmc Adenocarcinoma of the gastroesophageal junction: influence of esophageal resection margin and operative approach on outcome
    Andrew P Barbour
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Surg 246:1-8. 2007
    ..To determine whether the length of esophageal resection or the operative approach influences outcome for patients with adenocarcinoma of the gastroesophageal junction (GEJ)...
  41. ncbi request reprint Assessment of therapy responses and prediction of survival in malignant pleural mesothelioma through computer-aided volumetric measurement on computed tomography scans
    Fan Liu
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Columbia University, New York, New York
    J Thorac Oncol 5:879-84. 2010
    ....
  42. doi request reprint Patterns of local and nodal failure in malignant pleural mesothelioma after extrapleural pneumonectomy and photon-electron radiotherapy
    Vishal Gupta
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York City, NY 10065, USA
    J Thorac Oncol 4:746-50. 2009
    ....
  43. ncbi request reprint SCCRO expression correlates with invasive progression in bronchioloalveolar carcinoma
    Inderpal S Sarkaria
    Laboratory of Epithelial Cancer Biology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 78:1734-41. 2004
    ..We hypothesized that SCCRO expression would correlate with invasive tumor phenotypes and worse survival in BAC...
  44. pmc Core needle lung biopsy specimens: adequacy for EGFR and KRAS mutational analysis
    Stephen B Solomon
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Howard 118, New York, NY 10021, USA
    AJR Am J Roentgenol 194:266-9. 2010
    ....
  45. doi request reprint Use of epidermal growth factor receptor/Kirsten rat sarcoma 2 viral oncogene homolog mutation testing to define clonal relationships among multiple lung adenocarcinomas: comparison with clinical guidelines
    Nicolas Girard
    Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Chest 137:46-52. 2010
    ..Here, we report on seven patients in whom epidermal growth factor receptor (EGFR) and Kirsten-rat sarcoma 2 viral oncogene homolog (KRAS) tumor mutation status was used to determine clonal relationships among multiple lung lesions...
  46. ncbi request reprint Endoscopic ultrasound predicts outcomes for patients with adenocarcinoma of the gastroesophageal junction
    Andrew P Barbour
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Am Coll Surg 205:593-601. 2007
    ..The purpose of this study was to compare preoperative EUS staging with postoperative pathologic staging and to assess the ability of EUS to predict survival after resection for GEJ adenocarcinoma...
  47. doi request reprint Therapeutic sentinel lymph node imaging
    Stefan S Kachala
    Division of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Semin Thorac Cardiovasc Surg 21:327-38. 2009
    ..In this review, we summarize the novel preclinical agents for identification and treatment of tumor bearing LNs and discuss their potential for clinical translation...
  48. ncbi request reprint Induction chemoradiation and surgical resection for superior sulcus non-small-cell lung carcinomas: long-term results of Southwest Oncology Group Trial 9416 (Intergroup Trial 0160)
    Valerie W Rusch
    Thoracic Surgery Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Clin Oncol 25:313-8. 2007
    ..On the basis of improved outcomes in other subsets of stage III NSCLC, this trial tested the feasibility of induction chemoradiotherapy for SS NSCLC...
  49. doi request reprint Lung adenocarcinoma: modification of the 2004 WHO mixed subtype to include the major histologic subtype suggests correlations between papillary and micropapillary adenocarcinoma subtypes, EGFR mutations and gene expression analysis
    Noriko Motoi
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 32:810-27. 2008
    ..Such an approach should be considered in future studies for validation in other datasets...
  50. doi request reprint Extrapleural pneumonectomy versus pleurectomy/decortication in the surgical management of malignant pleural mesothelioma: results in 663 patients
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 135:620-6, 626.e1-3. 2008
    ..We performed a multi-institutional study to increase statistical power to detect significant differences in outcome between extrapleural pneumonectomy and pleurectomy/decortication...
  51. ncbi request reprint Prognostic factors after combined modality treatment of squamous cell carcinoma of the esophagus
    Nabil P Rizk
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Room C 883, New York, NY 10021, USA
    J Thorac Oncol 2:1117-23. 2007
    ..In this study, we evaluated prognostic factors among patients with squamous cell carcinoma (SCC) of the esophagus who have undergone a similar treatment regimen...
  52. doi request reprint DNA damage and repair capacity in patients with lung cancer: prediction of multiple primary tumors
    Irene Orlow
    Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Clin Oncol 26:3560-6. 2008
    ..Therefore, we evaluated constitutive and induced DNA damage, and repair capacity, in patients with multiple NSCLCs (cases) and compared the results to those obtained in patients with a single NSCLC (controls)...
  53. doi request reprint The impact of lymph node station on survival in 348 patients with surgically resected malignant pleural mesothelioma: implications for revision of the American Joint Committee on Cancer staging system
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Cardiovasc Surg 136:605-10. 2008
    ..The American Joint Committee on Cancer staging system groups N1 and N2 disease together as stage III. The goal of this study was to define the prognostic value of specific nodal stations...
  54. pmc Morphologic features of adenocarcinoma of the lung predictive of response to the epidermal growth factor receptor kinase inhibitors erlotinib and gefitinib
    Maureen F Zakowski
    Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Arch Pathol Lab Med 133:470-7. 2009
    ..A subset of lung adenocarcinomas appears preferentially sensitive to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). EGFR-activating mutations and never smoking are associated with response to TKIs...
  55. ncbi request reprint Predictive value of initial PET-SUVmax in patients with locally advanced esophageal and gastroesophageal junction adenocarcinoma
    Nabil P Rizk
    Memorial Sloan Kettering Cancer Center, New York City, New York 10021, USA
    J Thorac Oncol 4:875-9. 2009
    ..In this study, we analyze the impact of the pretreatment PET SUVmax in patients with locally advanced esophageal adenocarcinoma who undergo preoperative chemoradiotherapy...
  56. pmc Multicenter phase II trial of neoadjuvant pemetrexed plus cisplatin followed by extrapleural pneumonectomy and radiation for malignant pleural mesothelioma
    Lee M Krug
    Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Clin Oncol 27:3007-13. 2009
    ....
  57. ncbi request reprint Comparison of patterns of relapse in thymic carcinoma and thymoma
    James Huang
    Department of Surgery, Thoracic Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 138:26-31. 2009
    ..We reviewed our recent experience with the surgical management of thymic tumors and compared the outcomes and patterns of relapse between patients with thymic carcinoma and those with thymoma...
  58. ncbi request reprint Lobectomy by video-assisted thoracic surgery (VATS) versus thoracotomy for lung cancer
    Raja M Flores
    Department of Surgery, Thoracic Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 138:11-8. 2009
    ..However, a well-balanced comparison of the two procedures is lacking in the literature...
  59. doi request reprint International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma
    William D Travis
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Thorac Oncol 6:244-85. 2011
    ....
  60. ncbi request reprint Induction chemotherapy, extrapleural pneumonectomy, and postoperative high-dose radiotherapy for locally advanced malignant pleural mesothelioma: a phase II trial
    Raja M Flores
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Oncol 1:289-95. 2006
    ..We designed this clinical trial to test the feasibility of induction chemotherapy followed by EPP and RT in locally advanced MPM with the ultimate aim of improving survival...
  61. ncbi request reprint Positron emission tomography predicts survival in malignant pleural mesothelioma
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Cardiovasc Surg 132:763-8. 2006
    ..Because mediastinal nodal metastasis is known to be associated with poor prognosis, we hypothesized that standard uptake value on fluorodeoxyglucose positron emission tomography might independently predict survival...
  62. ncbi request reprint Robotic assistance for video-assisted thoracic surgical lobectomy: technique and initial results
    Bernard J Park
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 131:54-9. 2006
    ..There is little experience with telerobotic assistance for video-assisted thoracic surgical lobectomy. We developed a technique for robotic assistance during video-assisted thoracic surgical lobectomy and report our initial results...
  63. ncbi request reprint Extrapleural pneumonectomy in children
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Pediatr Surg 41:1738-42. 2006
    ..EPP in the pediatric population has not been reported in the literature. We report our experience of using EPP in children to treat a variety of malignancies that involve the pleural surface...
  64. ncbi request reprint Positron emission tomography defines metastatic disease but not locoregional disease in patients with malignant pleural mesothelioma
    Raja M Flores
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 126:11-6. 2003
    ..Small studies suggest that fluorodeoxyglucose-positron emission tomography may improve staging. We analyzed our experience to determine more definitively the potential utility of fluorodeoxyglucose-positron emission tomography...
  65. ncbi request reprint Management of major hemorrhage during mediastinoscopy
    Bernard J Park
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Room C 867, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 126:726-31. 2003
    ..The management of major hemorrhage complicating mediastinoscopy is not well described. We reviewed our experience to determine the frequency, optimal management strategy, and outcome of these injuries...
  66. ncbi request reprint Radiation-induced cellular DNA damage repair response enhances viral gene therapy efficacy in the treatment of malignant pleural mesothelioma
    Prasad S Adusumilli
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Surg Oncol 14:258-69. 2007
    ..Such stress response is beneficial for oncolytic viral therapy. We hypothesized that a combination of RT and NV1066, an oncolytic herpes virus, might exert an additive or synergistic effect in the treatment of MPM...
  67. ncbi request reprint An initial experience with FDG-PET in the imaging of residual disease after induction therapy for lung cancer
    Tim Akhurst
    Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 73:259-64; discussion 264-6. 2002
    ..Aside from one 9-patient study, there are no data comparing FDG-PET imaging with surgical staging of NSCLC after induction therapy...
  68. ncbi request reprint Surgical treatment of superior sulcus tumors with spinal and brachial plexus involvement
    Mark H Bilsky
    Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Neurosurg 97:301-9. 2002
    ..Advances in spinal surgery, the application of magnetic resonance (MR) imaging, and improvements in neoadjuvant therapy require a reassessment of the potential for complete resection...
  69. ncbi request reprint A phase II trial of chemotherapy and surgery for non-small cell lung cancer patients with a synchronous solitary metastasis
    Robert J Downey
    Thoracic Services, Memorial Sloan Kettering Cancer Center, Division of Thoracic Surgery, 1275 York Avenue, New York, NY 10021, USA
    Lung Cancer 38:193-7. 2002
    ..The feasibility and potential benefit of combining surgery and chemotherapy in this setting are unclear. Therefore, we performed a prospective trial to test this therapeutic approach...
  70. ncbi request reprint Squamous cell carcinoma related oncogene regulates angiogenesis through vascular endothelial growth factor-A
    Simon G Talbot
    Laboratory of Epithelial Cancer, Biology, and Head and Neck Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Ann Surg Oncol 11:530-4. 2004
    ..The present study aims to confirm and validate this link between SCCRO and VEGF-A expression in an ex vivo human tumor cohort...
  71. ncbi request reprint American Joint Committee on Cancer staging system does not accurately predict survival in patients receiving multimodality therapy for esophageal adenocarcinoma
    Nabil P Rizk
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Clin Oncol 25:507-12. 2007
    ..However, none of these methods has been formally evaluated. The purpose of this study was to establish prognostic pathologic variables after CRT...
  72. ncbi request reprint A pilot trial of high-dose-rate intraoperative radiation therapy for malignant pleural mesothelioma
    Kenneth E Rosenzweig
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Brachytherapy 4:30-3. 2005
    ..To report results of a phase II trial of high-dose-rate intra-operative radiation therapy (HDR-IORT) for malignant pleural mesothelioma (MPM)...
  73. ncbi request reprint Surgical management of thoracic malignancies invading the heart or great vessels
    Bernard J Park
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 78:1024-30. 2004
    ..We reviewed our experience of 10 patients treated surgically, either primarily or as a component of multimodality therapy, to assess feasibility and results...
  74. ncbi request reprint Video-assisted thoracic surgery does not reduce the incidence of postoperative atrial fibrillation after pulmonary lobectomy
    Bernard J Park
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 133:775-9. 2007
    ..The objective was to define the incidence of atrial fibrillation after video-assisted thoracic surgery lobectomy and determine whether video-assisted thoracic surgery reduces atrial fibrillation rate compared with thoracotomy...
  75. ncbi request reprint Hemithoracic radiation after extrapleural pneumonectomy for malignant pleural mesothelioma
    Santosh Yajnik
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Int J Radiat Oncol Biol Phys 56:1319-26. 2003
    ..Our institution recently published results showing that extrapleural pneumonectomy (EPP) followed by hemithoracic radiation yielded excellent local control. This paper reports our technique for high-dose hemithoracic radiation after EPP...
  76. ncbi request reprint Outcomes of induction chemotherapy followed by chemoradiation using intensity-modulated radiation therapy for esophageal adenocarcinoma
    N Gerber
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Dis Esophagus 27:235-41. 2014
    ..The use of IMRT may allow for integration of more intensified systemic therapy or radiation dose escalation for esophageal adenocarcinoma, ultimately improving outcomes for patients with this aggressive disease. ..
  77. pmc Virally-directed fluorescent imaging (VFI) can facilitate endoscopic staging
    P S Adusumilli
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Surg Endosc 20:628-35. 2006
    ..We sought to determine the feasibility of GFP-guided imaging technology in the intraoperative detection of small tumor nodules...
  78. ncbi request reprint Are cancers of the esophagus, gastroesophageal junction, and cardia one disease, two, or several?
    Valerie W Rusch
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Semin Oncol 31:444-9. 2004
    ..Much more investigation is required to confirm or refute these apparent differences, which can affect clinical treatment...
  79. ncbi request reprint Experimental therapeutics with a new 10-deazaaminopterin in human mesothelioma: further improving efficacy through structural design, pharmacologic modulation at the level of MRP ATPases, and combined therapy with platinums
    N Z Khokhar
    Program in Molecular Pharmacology and Experimental Therapeutics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
    Clin Cancer Res 7:3199-205. 2001
    ..These results strongly suggest that PDX has significant potential in the treatment of human pleural mesothelioma, particularly when coadministered with probenecid or combined with platinum compounds...
  80. pmc Minimally invasive localization of oncolytic herpes simplex viral therapy of metastatic pleural cancer
    B M Stiles
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Cancer Gene Ther 13:53-64. 2006
    ....
  81. ncbi request reprint Should the esophageal cancer staging system be revised?
    Valerie W Rusch
    J Thorac Cardiovasc Surg 125:992-3. 2003
  82. ncbi request reprint Results of the American College of Surgeons Oncology Group Z0050 trial: the utility of positron emission tomography in staging potentially operable non-small cell lung cancer
    Carolyn E Reed
    Hollings Cancer Center, Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston 29425, USA
    J Thorac Cardiovasc Surg 126:1943-51. 2003
    ....
  83. ncbi request reprint Pemetrexed and cisplatin for malignant pleural mesothelioma: a new standard of care?
    Valerie W Rusch
    J Clin Oncol 21:2629-30. 2003
  84. ncbi request reprint High-resolution computed tomography in clinical T1 N0 M0 adenocarcinoma of the lung
    Valerie W Rusch
    J Thorac Cardiovasc Surg 124:221-2. 2002
  85. ncbi request reprint Surgical techniques for pulmonary metastasectomy
    Valerie W Rusch
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Semin Thorac Cardiovasc Surg 14:4-9. 2002
    ..Stapled and precision electrocautery wedge resections remain the most common techniques for parenchymal resection...
  86. ncbi request reprint Cost-effectiveness of pulmonary resection and systemic chemotherapy in the management of metastatic soft tissue sarcoma: a combined analysis from the University of Texas M. D. Anderson and Memorial Sloan-Kettering Cancer Centers
    Geoffrey A Porter
    Dalhousie University, Halifax, Nova Scotia, Canada
    J Thorac Cardiovasc Surg 127:1366-72. 2004
    ..We sought to determine the cost-effectiveness of different treatment strategies for patients with pulmonary metastases from soft tissue sarcoma...
  87. ncbi request reprint Prediction rule for atrial fibrillation after major noncardiac thoracic surgery
    Rod S Passman
    Northwestern University Feinberg School of Medicine and the Feinberg Cardiovascular Institute, Chicago, Illinois 60611, USA
    Ann Thorac Surg 79:1698-703. 2005
    ..We sought to derive and validate a clinical prediction rule to risk-stratify patients for postoperative AF...
  88. ncbi request reprint Mediastinoscopy: an endangered species?
    Valerie W Rusch
    J Clin Oncol 23:8283-5. 2005
  89. ncbi request reprint The utility of positron emission tomography in staging of potentially operable carcinoma of the thoracic esophagus: results of the American College of Surgeons Oncology Group Z0060 trial
    Bryan F Meyers
    Department of Surgery, Washington University School of Medicine, St Louis, MO
    J Thorac Cardiovasc Surg 133:738-45. 2007
    ....
  90. ncbi request reprint A phase II study of intrapleural immunochemotherapy, pleurectomy/decortication, radiotherapy, systemic chemotherapy, and long-term subcutaneous IL-2 in stage II-III malignant pleural mesothelioma
    Valerie W Rusch
    Eur J Cardiothorac Surg 31:534-5. 2007
  91. ncbi request reprint Adjuvant therapy in non-small cell lung cancer
    Valerie W Rusch
    Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Ann Thorac Surg 84:1793-4. 2007
  92. ncbi request reprint Mortality increases for octogenarians undergoing esophagogastrectomy for esophageal cancer
    Alexander H Moskovitz
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 82:2031-6; discussion 2036. 2006
    ..Because this risk is poorly defined, we sought to determine whether extreme age (>80 years) is an independent risk factor after esophagectomy...
  93. ncbi request reprint Yield of brain 18F-FDG PET in evaluating patients with potentially operable non-small cell lung cancer
    Katherine E Posther
    Department of Surgery, Duke Comprehensive Cancer Center, Duke University Medical Center, Durham, North Carolina, USA
    J Nucl Med 47:1607-11. 2006
    ..Here, we report the yield of brain PET in evaluating, for potential intracranial metastases, patients who have undergone previous brain CT or MRI with negative findings...
  94. ncbi request reprint Multimodality therapy for locally advanced thymomas: state of the art or investigational therapy?
    James Huang
    Ann Thorac Surg 85:365-7. 2008
  95. ncbi request reprint Morbidity and mortality of major pulmonary resections in patients with early-stage lung cancer: initial results of the randomized, prospective ACOSOG Z0030 trial
    Mark S Allen
    Ann Thorac Surg 81:1013-9; discussion 1019-20. 2006
    ..Little prospective, multiinstitutional data exist regarding the morbidity and mortality after major pulmonary resections for lung cancer or whether a mediastinal lymph node dissection increases morbidity and mortality...
  96. ncbi request reprint Results of chest wall resection and reconstruction with and without rigid prosthesis
    Michael J Weyant
    Department of Surgery, Thoracic Service, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 81:279-85. 2006
    ..Chest wall resections are associated with significant morbidity, with respiratory failure in as many as 27% of patients. We hypothesized that our selective use of a rigid prosthesis for reconstruction reduces respiratory complications...
  97. ncbi request reprint Patterns of surgical care of lung cancer patients
    Alex G Little
    Department of Surgery, Wright State University School of Medicine, Dayton, Ohio, USA
    Ann Thorac Surg 80:2051-6; discussion 2056. 2005
    ..This survey was performed to determine the patterns of surgical care provided patients with non-small cell lung carcinoma (NSCLC)...
  98. pmc Cisplatin-induced GADD34 upregulation potentiates oncolytic viral therapy in the treatment of malignant pleural mesothelioma
    Prasad S Adusumilli
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer Biol Ther 5:48-53. 2006
    ..We hypothesized that cisplatin upregulates GADD34 expression, which enhances NV1066 replication and oncolysis...
  99. pmc Radiation therapy potentiates effective oncolytic viral therapy in the treatment of lung cancer
    Prasad S Adusumilli
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 80:409-16; discussion 416-7. 2005
    ..We hypothesized that radiation therapy may potentiate efficacy of oncolytic viral therapy by upregulating GADD34 and promoting viral replication...
  100. ncbi request reprint Scalpels, beams, drugs, and dreams: challenges of stage IIIA-N2 non-small-cell lung cancer
    David H Johnson
    J Natl Cancer Inst 99:415-8. 2007