Research Topics
| C S PortlockSummaryAffiliation: Memorial Sloan-Kettering Cancer Center Country: USA Publications
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Detail Information
Publications
Infectious disease associations in advanced stage, indolent lymphoma (follicular and nonfollicular): developing a lymphoma prevention strategyC S Portlock
Department of Medicine, Memorial Sloan Kettering Cancer Center, NY 10021, USA
Ann Oncol 19:254-8. 2008..pylori, hepatitis C and Borrelia serologies, Borrelia and Chlamydia fixed tissue PCR, Chlamydia peripheral blood mononuclear cell PCR and hydrogen breath test for small bowel bacterial overgrowth (SBBO) were obtained...
Anti-angiogenesis and diffuse large B-cell lymphoma: a new treatment opportunity?C Portlock
Department of Medicine, Memorial Sloan Kettering, Cancer Center, New York, NY 10021, USA
Leuk Lymphoma 47:961-2. 2006
ReviewCarol S Portlock
Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
Clin Adv Hematol Oncol 2:820. 2004
The NHL-15 protocol for aggressive non-Hodgkin's lymphomas: a sequential dose-dense, dose-intense regimen of doxorubicin, vincristine and high-dose cyclophosphamideC S Portlock
Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Ann Oncol 15:1495-503. 2004..The NHL-15 protocol is a novel, dose-intense, dose-dense, sequential chemotherapy program developed to improve outcome in advanced, aggressive non-Hodgkin's lymphomas...
Adverse prognostic significance of CD20 positive Reed-Sternberg cells in classical Hodgkin's diseaseCarol S Portlock
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, USA
Br J Haematol 125:701-8. 2004..CD20(+) cHD is a poor prognostic factor for TTF and OS. All cHD cases should be immunophenotyped for CD20. A large prospective trial is needed to confirm these findings...
Stanford V program for locally extensive and advanced Hodgkin lymphoma: the Memorial Sloan-Kettering Cancer Center experienceS M Edwards-Bennett
Lymphoma Disease Management Team and Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Ann Oncol 21:574-81. 2010..We retrospectively examined whether treatment at our institution carefully following Stanford V guidelines would confirm the original Stanford outcome data...
Ifosfamide, carboplatin, and etoposide: a highly effective cytoreduction and peripheral-blood progenitor-cell mobilization regimen for transplant-eligible patients with non-Hodgkin's lymphomaC H Moskowitz
Lymphoma and Hematology Services, Department of Medicine, and Departments of Radiotherapy, Pathology, and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Clin Oncol 17:3776-85. 1999....
Maintaining the dose intensity of ICE chemotherapy with a thrombopoietic agent, PEG-rHuMGDF, may confer a survival advantage in relapsed and refractory aggressive non-Hodgkin lymphomaC H Moskowitz
Hematology Service, New York, NY, USA
Ann Oncol 18:1842-50. 2007..We incorporated a thrombopoietic agent into the ICE chemotherapy program to potentially: decrease platelet associated toxicities, augment stem cell collection and maintain dose intensity...
Prognostic impact of proliferative index determined by quantitative image analysis and the International Prognostic Index in patients with mantle cell lymphomaR Schaffel
Lymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Ann Oncol 21:133-9. 2010..The mantle cell international prognostic index (MIPI) has been reported to have prognostic importance. In this study, we determined the prognostic value of the PI as determined by quantitative image analysis in MCL...
Establishment of a human cell line (SKI-DLCL-1) with a t(1;14)(q21;q32) translocation from the ascites of a patient with diffuse large cell lymphomaA Goy
Department of Medicine, Memorial Hospital, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
Leuk Lymphoma 40:419-23. 2001..In addition, the BCL9 gene was not over-expressed in SKI-DLCL-1 cell line. The identification of a new locus at 1q21 will help clarify the pathogenesis of B-cell malignancies with a translocation involving this locus...
CHOP with high dose cyclophosphamide consolidation versus CHOP alone as initial therapy for advanced stage, indolent non-Hodgkin's lymphomasDorothy Pan
Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
Leuk Lymphoma 44:967-71. 2003..No myelodysplasia or acute leukemia has been seen to date. With no obvious improvement in CR and with greater hematologic toxicity than CHOP, CHOP-HC is not recommended for treatment of indolent non-Hodgkin's lymphomas...
Long-term cardiac and pulmonary complications of cancer therapyJoachim Yahalom
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Hematol Oncol Clin North Am 22:305-18, vii. 2008..Potential preventive measures for high-risk patients are of increasing interest but remain experimental...
Primary follicular lymphoma of the gastrointestinal tract: a clinical and pathologic study of 26 casesJinru Shia
Department of Pathology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, U.S.A
Am J Surg Pathol 26:216-24. 2002..The estimated 5-year disease-free survival was 62%, and median disease-free survival was 69 months. The estimated 5-year relapse-free survival was 54%, and the median relapse-free survival was 63 months...
The clinical course of nonsmall cell lung carcinoma in survivors of Hodgkin diseaseScott A Laurie
Thoracic Oncology Service, Division of Solid Tumor Oncology, Memorial Sloan-Kettering Cancer Center, Weill Medical College of Cornell University, New York, New York 10021, USA
Cancer 95:119-26. 2002..Patients who are diagnosed with HD should abstain from smoking. Physicians should assess specifically the smoking status of all HD patients and prescribe a smoking cessation program...
Stanford V and radiotherapy for Hodgkin's diseaseCarol S Portlock
Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Curr Oncol Rep 4:413. 2002
CHOP and rituximab in elderly patientsCarol S Portlock
Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Curr Oncol Rep 4:414. 2002
Primary mediastinal large B-cell lymphoma: optimal therapy and prognostic factor analysis in 141 consecutive patients treated at Memorial Sloan Kettering from 1980 to 1999Paul A Hamlin
Medicine Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Br J Haematol 130:691-9. 2005....
Results of a prospective randomized clinical trial of doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) followed by radiation therapy (RT) versus ABVD alone for stages I, II, and IIIA nonbulky Hodgkin diseaseDavid J Straus
Memorial Sloan Kettering Cancer Center, SR 441B Box 406, 1275 York Ave, New York, NY 10021, USA
Blood 104:3483-9. 2004..Although significant differences were not seen, it is possible that a benefit in outcome of less than 20% for CMT might be seen in a larger trial...
Rituximab for aggressive non-Hodgkin's lymphomas relapsing after or refractory to autologous stem cell transplantationDorothy Pan
Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
Cancer J 8:371-6. 2002..DISCUSSION: Rituximab is effective and well-tolerated palliative treatment for aggressive non-Hodgkin's lymphomas that relapse after or is refractory to autologous stem cell transplantation...
Age-adjusted International Prognostic Index predicts autologous stem cell transplantation outcome for patients with relapsed or primary refractory diffuse large B-cell lymphomaPaul A Hamlin
Lymphoma and Hematology Services, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan-Kettering Cancer Center, Box 350, 1275 York Ave, New York, NY, 10021
Blood 102:1989-96. 2003..This powerful prognostic instrument should be used to evaluate new treatment approaches and to compare results of different regimens...
Nemaline myopathy: a possible late complication of Hodgkin's disease therapyCarol S Portlock
Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
Hum Pathol 34:816-8. 2003..We are unaware of previous reports documenting such a phenomenon, which suggests that nemaline myopathy may evolve as a radiation-related disorder...
The diminishing role of surgery in the treatment of gastric lymphomaSam S Yoon
Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA
Ann Surg 240:28-37. 2004..CONCLUSION: The treatment of gastric lymphoma continues to evolve, and surgical resection is now uncommonly a part of the initial management strategy...
T-cell rich B-cell lymphoma: clinical distinctiveness and response to treatment in 45 patientsJonathan A Ripp
Yale University School of Medicine, New Haven, CT USA
Leuk Lymphoma 43:1573-80. 2002..Initial Hodgkin's disease-directed (HD-directed) chemotherapy should be avoided, although salvage transplantation may result in prolonged survival...
Nodular lymphocyte predominant Hodgkin's diseaseCarol S Portlock
Memorial Sloan-Kettering Cancer Center New York, New York 10021, USA
Cancer Treat Res 131:353-62. 2006
Pegylated interferon plus rituximab in advanced stage, indolent lymphoma: is there CD20 antigen upregulation?Carol S Portlock
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Leuk Lymphoma 47:1260-4. 2006..9%). PegIFN plus rituximab as delivered in this study is not recommended. PegIFN does not appear to upregulate CD20 expression in peripheral lymph node tumor cells...
Unusual abdominal tumors, case 2. Localized amyloid associated with gastric adenocarcinomaDavid Z Chang
Memorial Sloan-Kettering Cancer Center, New York, NY, USA
J Clin Oncol 22:1520-2. 2004
