Iain J Nixon

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. doi Thyroid cancer: surgery for the primary tumor
    I J Nixon
    Head and Neck Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Oral Oncol 49:654-8. 2013
  2. doi Nomogram for predicting malignancy in thyroid nodules using clinical, biochemical, ultrasonographic, and cytologic features
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Centre, New York, NY 10065, USA
    Surgery 148:1120-7; discussion 1127-8. 2010
  3. doi The impact of nodal status on outcome in older patients with papillary thyroid cancer
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, NY
    Surgery 156:137-46. 2014
  4. doi The results of selective use of radioactive iodine on survival and on recurrence in the management of papillary thyroid cancer, based on Memorial Sloan-Kettering Cancer Center risk group stratification
    Iain J Nixon
    Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Thyroid 23:683-94. 2013
  5. doi Observation of clinically negative central compartment lymph nodes in papillary thyroid carcinoma
    Iain J Nixon
    Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, NY
    Surgery 154:1166-72; discussion 1172-3. 2013
  6. doi Undetectable thyroglobulin after total thyroidectomy in patients with low- and intermediate-risk papillary thyroid cancer--is there a need for radioactive iodine therapy?
    Tihana Ibrahimpasić
    Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Surgery 152:1096-105. 2012
  7. pmc The impact of distant metastases at presentation on prognosis in patients with differentiated carcinoma of the thyroid gland
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer, 1275 York Ave, New York, NY 10065, USA
    Thyroid 22:884-9. 2012
  8. doi Nomogram for selecting thyroid nodules for ultrasound-guided fine-needle aspiration biopsy based on a quantification of risk of malignancy
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Head Neck 35:1022-5. 2013
  9. doi Disease-related death in patients who were considered free of macroscopic disease after initial treatment of well-differentiated thyroid carcinoma
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Thyroid 21:501-4. 2011
  10. pmc The impact of microscopic extrathyroid extension on outcome in patients with clinical T1 and T2 well-differentiated thyroid cancer
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Surgery 150:1242-9. 2011

Collaborators

Detail Information

Publications34

  1. doi Thyroid cancer: surgery for the primary tumor
    I J Nixon
    Head and Neck Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Oral Oncol 49:654-8. 2013
    ..The focus of this article is WDTC, however the principles of management of the primary in medullary and anaplastic carcinoma are also discussed...
  2. doi Nomogram for predicting malignancy in thyroid nodules using clinical, biochemical, ultrasonographic, and cytologic features
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Centre, New York, NY 10065, USA
    Surgery 148:1120-7; discussion 1127-8. 2010
    ..Our aim was to create a nomogram to predict accurately the chance of malignancy within a thyroid nodule...
  3. doi The impact of nodal status on outcome in older patients with papillary thyroid cancer
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, NY
    Surgery 156:137-46. 2014
    ..The objective of this study was to determine the impact of clinically or radiologically detected nodal metastases on outcome in patients 45 years of age or older...
  4. doi The results of selective use of radioactive iodine on survival and on recurrence in the management of papillary thyroid cancer, based on Memorial Sloan-Kettering Cancer Center risk group stratification
    Iain J Nixon
    Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Thyroid 23:683-94. 2013
    ..The aim of this study was to analyze our institutional experience of the use of RRA in the management of papillary thyroid cancer, with a particular focus on outcomes for those patients selected not to receive RRA...
  5. doi Observation of clinically negative central compartment lymph nodes in papillary thyroid carcinoma
    Iain J Nixon
    Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, NY
    Surgery 154:1166-72; discussion 1172-3. 2013
    ..The role of prophylactic central neck dissection in the management of papillary thyroid cancer (PTC) is controversial. We report our experience of an observational approach to the cN0 neck in PTC...
  6. doi Undetectable thyroglobulin after total thyroidectomy in patients with low- and intermediate-risk papillary thyroid cancer--is there a need for radioactive iodine therapy?
    Tihana Ibrahimpasić
    Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Surgery 152:1096-105. 2012
    ..The objectives of this study were to report the risk of recurrence in patients with PTC who had an undetectable Tg level after total thyroidectomy managed with postoperative RAI and without RAI...
  7. pmc The impact of distant metastases at presentation on prognosis in patients with differentiated carcinoma of the thyroid gland
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer, 1275 York Ave, New York, NY 10065, USA
    Thyroid 22:884-9. 2012
    ..The objective of this study was to report outcomes for patients presenting with distant metastases managed by thyroidectomy and radioactive iodine (RAI) therapy...
  8. doi Nomogram for selecting thyroid nodules for ultrasound-guided fine-needle aspiration biopsy based on a quantification of risk of malignancy
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Head Neck 35:1022-5. 2013
    ....
  9. doi Disease-related death in patients who were considered free of macroscopic disease after initial treatment of well-differentiated thyroid carcinoma
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Thyroid 21:501-4. 2011
    ..The objective of our study was to report the cause of death from thyroid cancer in patients with WDTC treated with curative intent with surgery ± adjuvant radioactive iodine...
  10. pmc The impact of microscopic extrathyroid extension on outcome in patients with clinical T1 and T2 well-differentiated thyroid cancer
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Surgery 150:1242-9. 2011
    ....
  11. doi Changing trends in well differentiated thyroid carcinoma over eight decades
    Iain J Nixon
    Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Int J Surg 10:618-23. 2012
    ..The objective of this study is to present the changes in incidence, presentation, management and outcomes of WDTC within our institution over the past 8 decades...
  12. doi Thyroid lobectomy for treatment of well differentiated intrathyroid malignancy
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Surgery 151:571-9. 2012
    ..The objective of this study was to report our experience of T1T2N0 WDTC managed by either thyroid lobectomy or total thyroidectomy...
  13. doi Level 7 disease does not confer worse outcome than level 6 disease in differentiated thyroid cancer
    Laura Y Wang
    Division of Head and Neck Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Surg Oncol 22:441-5. 2015
    ..This results in upstaging of patients older than 45 years of age from stage III to IV. Our objective was to determine if patients with level 7 disease had poorer outcome in comparison to patients with isolated level 6 disease...
  14. doi Comparable outcomes for patients with pT1a and pT1b differentiated thyroid cancer: Is there a need for change in the AJCC classification system?
    Laura Y Wang
    Department of Surgery, Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, NY
    Surgery 156:1484-9; discussion 1489-90. 2014
    ..In 2009, the American Thyroid Association recommended total thyroidectomy for tumors >1 cm in contrast to the possibility of lobectomy for tumors ≤ 1 cm. Our aim was to investigate the prognostic significance of a 1-cm tumor cutoff...
  15. doi Central lymph node characteristics predictive of outcome in patients with differentiated thyroid cancer
    Laura Y Wang
    1 Department of Surgery, Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, New York
    Thyroid 24:1790-5. 2014
    ....
  16. doi Multi-organ distant metastases confer worse disease-specific survival in differentiated thyroid cancer
    Laura Y Wang
    1 Department of Surgery, Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, New York
    Thyroid 24:1594-9. 2014
    ..The aims of this study were to determine the impact of single and multi-organ distant metastases (SODM and MODM) on survival, and identify factors that predict SODM progressing to MODM...
  17. doi Outcome of patients with early T1 and T2 squamous cell carcinoma of the base of tongue managed by conventional surgery with adjuvant postoperative radiation
    N Gopalakrishna Iyer
    Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Head Neck 35:999-1006. 2013
    ..The aim was to report our experience in conventional surgical management with particular focus on T1/T2 tumors, which may be candidates for minimally invasive techniques...
  18. doi Thyroid isthmusectomy for well-differentiated thyroid cancer
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Surg Oncol 18:767-70. 2011
    ..This study was designed to analyze outcomes in patients treated with isthmusectomy for small well-differentiated thyroid cancer (WDTC) at our institution...
  19. doi Incidence and significance of Delphian node metastasis in papillary thyroid cancer
    N Gopalakrishna Iyer
    Department of Surgery, Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York 10065, USA
    Ann Surg 253:988-91. 2011
    ..The objective of this study was to determine the incidence and significance of Delphian node (DN) metastasis in papillary thyroid cancer...
  20. doi Surgical management of metastases to the thyroid gland
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Surg Oncol 18:800-4. 2011
    ..Metastases to the thyroid gland are uncommon, with rates reported between 0.02% and 1.4% of surgically resected thyroid specimens. Our goal was to present our experience with surgical management of metastases to the thyroid gland...
  21. doi Prognostic value of vascular invasion in well-differentiated papillary thyroid carcinoma
    Volkert B Wreesmann
    1 Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York
    Thyroid 25:503-8. 2015
    ....
  22. doi Surgical management of squamous cell carcinoma of the soft palate: factors predictive of outcome
    N Gopalakrishna Iyer
    Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Head Neck 34:1071-80. 2012
    ..Squamous cell carcinoma of the soft palate (SCCSP) is uncommon. The aim of this study was to report our experience and identify factors predictive of outcome...
  23. doi Electronic synoptic operative reporting for thyroid surgery using an electronic data management system: potential for prospective multicenter data collection
    N Gopalakrishna Iyer
    Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Surg Oncol 18:762-6. 2011
    ..Thyroid surgery lends itself to synoptic reporting, because there are a predefined number of essential intraoperative events and findings that every endocrine surgeon invariably records...
  24. doi Increasing diagnosis of subclinical thyroid cancers leads to spurious improvements in survival rates
    Allen S Ho
    Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York
    Cancer 121:1793-9. 2015
    ..Increasingly, more subclinical thyroid cancers are being diagnosed. The objective of the current study was to determine whether thyroid cancer survival rates have been affected by this phenomenon...
  25. doi Thyrotropin suppression increases the risk of osteoporosis without decreasing recurrence in ATA low- and intermediate-risk patients with differentiated thyroid carcinoma
    Laura Y Wang
    1 Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York
    Thyroid 25:300-7. 2015
    ..The objectives of this study were to examine the beneficial effects and the cardiac and skeletal toxicity of TSH suppression in well-differentiated thyroid carcinoma (DTC)...
  26. doi Pathologically determined tumor volume vs pathologic T stage in the prediction of outcome after surgical treatment of oropharyngeal squamous cell carcinoma
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York
    JAMA Otolaryngol Head Neck Surg 139:1151-5. 2013
    ..Traditional prognostic models for squamous cell carcinoma of the head and neck are based on the TNM staging system. However, there is growing evidence that tumor volume (TV) may be a more accurate predictor of outcome...
  27. pmc An integrated simulator for endolaryngeal surgery
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Laryngoscope 122:140-3. 2012
    ..Further applications could include development of surgical techniques and instruments, and use in accreditation of training and revalidation of trained surgeons...
  28. doi Thyroid metastasectomy
    Pablo H Montero
    Head and Neck Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer, New York, New York
    J Surg Oncol 109:36-41. 2014
    ..Selected patients could benefit from surgical treatment. Although most patients selected for surgery will not be cured, the aim of surgery is to avoid the complications of uncontrolled central neck disease...
  29. doi Malignancy rate in thyroid nodules classified as Bethesda category III (AUS/FLUS)
    Allen S Ho
    1 Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York
    Thyroid 24:832-9. 2014
    ..Our objective was to determine the risk of malignancy in thyroid FNAs categorized as AUS/FLUS at a comprehensive cancer center...
  30. doi The neoplastic goitre
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Ketttering Cancer Center, New York, NY, USA
    Curr Opin Otolaryngol Head Neck Surg 21:143-9. 2013
    ....
  31. doi Management of regional nodes in thyroid cancer
    Iain J Nixon
    Head and Neck Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Oral Oncol 49:671-5. 2013
    ..The focus of this article is WDTC, however the principles of management of the neck in medullary and anaplastic carcinoma are also discussed...
  32. doi Surgical diagnosis: frozen section and the extent of surgery
    Iain J Nixon
    Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Otolaryngol Clin North Am 47:519-28. 2014
    ..In addition, key findings in the operating room are discussed in relation to their impact on decision making. Long-term outcomes are presented for patients following surgery. ..
  33. doi Targeted therapy in thyroid cancer
    Iain J Nixon
    Department of Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Curr Opin Otolaryngol Head Neck Surg 21:130-4. 2013
    ..These changes form the basis for targeted therapies, which have been investigated with some success in patients with advanced, inoperable thyroid cancers and are the subject of this review...
  34. doi Factors predicting outcome in malignant minor salivary gland tumors of the oropharynx
    N Gopalakrishna Iyer
    Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Arch Otolaryngol Head Neck Surg 136:1240-7. 2010
    ..to report our experience in the care of patients with minor salivary gland cancers occurring only in the oropharynx and to determine factors predictive of outcome...