Garrett M Nash

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. ncbi A predictive model for lymph node yield in colon cancer resection specimens
    Garrett M Nash
    Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Ann Surg 253:318-22. 2011
  2. ncbi Close distal margin and rectal cancer recurrence after sphincter-preserving rectal resection
    Garrett M Nash
    Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Dis Colon Rectum 53:1365-73. 2010
  3. ncbi KRAS mutation and microsatellite instability: two genetic markers of early tumor development that influence the prognosis of colorectal cancer
    Garrett M Nash
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, USA
    Ann Surg Oncol 17:416-24. 2010
  4. ncbi Effects of obesity in rectal cancer surgery
    Hueylan Chern
    Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Am Coll Surg 211:55-60. 2010
  5. ncbi Challenging the feasibility and clinical significance of current guidelines on lymph node examination in rectal cancer in the era of neoadjuvant therapy
    Anand Govindarajan
    Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Clin Oncol 29:4568-73. 2011
  6. ncbi Recurrence rates and prognostic factors in ypN0 rectal cancer after neoadjuvant chemoradiation and total mesorectal excision
    Anand Govindarajan
    Department of Colorectal Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Surg Oncol 18:3666-72. 2011
  7. ncbi Long-term survival after transanal excision of T1 rectal cancer
    Garrett M Nash
    Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Dis Colon Rectum 52:577-82. 2009
  8. ncbi Immunohistochemistry as first-line screening for detecting colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome: a 2-antibody panel may be as predictive as a 4-antibody panel
    Jinru Shia
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Am J Surg Pathol 33:1639-45. 2009
  9. ncbi Pulmonary recurrence predominates after combined modality therapy for rectal cancer: an original retrospective study
    Peirong Ding
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Ann Surg 256:111-6. 2012
  10. ncbi Whole-mount pathologic analysis of rectal cancer following neoadjuvant therapy: implications of margin status on long-term oncologic outcome
    James J Mezhir
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Ann Surg 256:274-9. 2012

Collaborators

Detail Information

Publications29

  1. ncbi A predictive model for lymph node yield in colon cancer resection specimens
    Garrett M Nash
    Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Ann Surg 253:318-22. 2011
    ..To develop a predictive model of lymph node yield in a series of colon cancer resection specimens with detailed anatomic and surgical technique data...
  2. ncbi Close distal margin and rectal cancer recurrence after sphincter-preserving rectal resection
    Garrett M Nash
    Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Dis Colon Rectum 53:1365-73. 2010
    ..Negative surgical margins are important for local control of rectal cancer treated with sphincter-preserving surgery. However, the association of rectal cancer recurrence with close distal margin is not well established...
  3. ncbi KRAS mutation and microsatellite instability: two genetic markers of early tumor development that influence the prognosis of colorectal cancer
    Garrett M Nash
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, USA
    Ann Surg Oncol 17:416-24. 2010
    ....
  4. ncbi Effects of obesity in rectal cancer surgery
    Hueylan Chern
    Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Am Coll Surg 211:55-60. 2010
    ..In this study, we evaluate whether higher body mass index (BMI) compromises surgical resection in patients with locally advanced, mid-to-low rectal cancer after neoadjuvant therapy, adversely affecting long-term oncologic outcomes...
  5. ncbi Challenging the feasibility and clinical significance of current guidelines on lymph node examination in rectal cancer in the era of neoadjuvant therapy
    Anand Govindarajan
    Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Clin Oncol 29:4568-73. 2011
    ..We sought to examine the feasibility and clinical significance of current guidelines on nodal assessment in patients with rectal cancer (RC) treated with neoadjuvant radiation...
  6. ncbi Recurrence rates and prognostic factors in ypN0 rectal cancer after neoadjuvant chemoradiation and total mesorectal excision
    Anand Govindarajan
    Department of Colorectal Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Surg Oncol 18:3666-72. 2011
    ..Patients with pathologically node-negative tumors have an improved prognosis, but recurrence patterns and independent prognostic factors in these patients have been incompletely characterized...
  7. ncbi Long-term survival after transanal excision of T1 rectal cancer
    Garrett M Nash
    Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Dis Colon Rectum 52:577-82. 2009
    ..However, the impact of transanal excision on cancer mortality has not been adequately studied. The purpose of this study was to compare oncologic outcomes of transanal excision with those of radical resection...
  8. ncbi Immunohistochemistry as first-line screening for detecting colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome: a 2-antibody panel may be as predictive as a 4-antibody panel
    Jinru Shia
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Am J Surg Pathol 33:1639-45. 2009
    ..Such a cost-effective approach carries significant implication, as immunohistochemistry is being widely used as first-line screening for HNPCC...
  9. ncbi Pulmonary recurrence predominates after combined modality therapy for rectal cancer: an original retrospective study
    Peirong Ding
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Ann Surg 256:111-6. 2012
    ..To characterize patterns of recurrence in locally advanced rectal cancer treated with combined modality therapy (CMT): neoadjuvant chemoradiation + total mesorectal excision + adjuvant chemotherapy...
  10. ncbi Whole-mount pathologic analysis of rectal cancer following neoadjuvant therapy: implications of margin status on long-term oncologic outcome
    James J Mezhir
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Ann Surg 256:274-9. 2012
    ..We set out to determine the long-term oncologic impact of resection margins in patients with locally advanced rectal cancer using a comprehensive pathologic whole-mount section analysis...
  11. ncbi Improved testing for microsatellite instability in colorectal cancer using a simplified 3-marker assay
    Iyare Esemuede
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Surg Oncol 17:3370-8. 2010
    ..However, the optimal assay for MSI status is unknown. We have evaluated a simplified 3-marker assay for MSI and compared it with the 5-marker (NCI) assay to see if technical variations in MSI testing are important...
  12. ncbi Rate of residual disease after complete endoscopic resection of malignant colonic polyp
    Jean M Butte
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Dis Colon Rectum 55:122-7. 2012
    ..Following polypectomy, colectomy is performed selectively to ensure complete clearance of neoplasia...
  13. ncbi KRAS mutation correlates with accelerated metastatic progression in patients with colorectal liver metastases
    Garrett M Nash
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Surg Oncol 17:572-8. 2010
    ..To examine more directly whether KRAS mutations are associated with accelerated metastatic progression, we evaluated KRAS mutation as well as Ki-67 expression in patients with colorectal liver metastases not treated with cetuximab...
  14. ncbi Radical resection of rectal cancer primary tumor provides effective local therapy in patients with stage IV disease
    Garrett M Nash
    Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
    Ann Surg Oncol 9:954-60. 2002
    ..The extent of metastatic disease and the response to chemotherapy are the major determinants of survival. Effective systemic chemotherapy should be given high priority in the treatment of stage IV rectal cancer...
  15. ncbi Nonoperative management of rectal cancer with complete clinical response after neoadjuvant therapy
    James D Smith
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Ann Surg 256:965-72. 2012
    ....
  16. ncbi Patterns of failure in patients with early onset (synchronous) resectable liver metastases from rectal cancer
    Jean M Butte
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Cancer 118:5414-23. 2012
    ..In this study, the authors examined recurrence patterns and survival after resection of SLMRC...
  17. ncbi Early postoperative intraperitoneal chemotherapy following cytoreductive surgery for appendiceal mucinous neoplasms with isolated peritoneal metastasis
    Patrick L Wagner
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Dis Colon Rectum 55:407-15. 2012
    ..At our institution, patients undergoing complete cytoreduction in this setting typically receive multiple cycles of early postoperative intraperitoneal chemotherapy...
  18. ncbi Detection of HER-2/neu gene amplification in breast cancer using a novel polymerase chain reaction/ligase detection reaction technique
    Daniel R Nathanson
    Department of Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
    J Am Coll Surg 197:419-25. 2003
    ..This technique is an accurate and rapid alternative to FISH with the potential for automation and high throughput analysis of HER-2/neu status in breast cancer...
  19. ncbi c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases
    Zhao Shi Zeng
    Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Cancer Lett 265:258-69. 2008
    ..c-Met gene amplification is linked to metastatic progression, and is a viable target for a significant subset of advanced CRC...
  20. ncbi Response to neoadjuvant therapy in patients with early age-of-onset rectal cancer
    Emily Steinhagen
    Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Dis Colon Rectum 56:58-63. 2013
    ..The response to neoadjuvant treatment in patients ≤ 50 years of age is not known. Factors affecting the response to neoadjuvant therapy in this age group have not been evaluated...
  21. ncbi Systematic immunohistochemistry screening for Lynch syndrome in early age-of-onset colorectal cancer patients undergoing surgical resection
    Emily Steinhagen
    Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Am Coll Surg 214:61-7. 2012
    ..Our study describes the impact of routine immunohistochemistry (IHC) analysis of tumor tissue for loss of MMR protein expression in early age-of-onset CRC patients undergoing resection...
  22. ncbi Single-incision versus multiport laparoscopic right and hand-assisted left colectomy: a case-matched comparison
    Sang W Lee
    New York Presbyterian Hospital, Weill Cornell Medical College, New York, New York, USA
    Dis Colon Rectum 54:1355-61. 2011
    ..New technology for single-incision laparoscopic colectomy is now commercially available, yet advantages of this approach over multiport laparoscopic colectomy have not been demonstrated...
  23. ncbi HER 2/neu expression and gene amplification in colon cancer
    Daniel R Nathanson
    Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
    Int J Cancer 105:796-802. 2003
    ..These data indicate that the primary mechanism of dysregulated HER 2/neu expression in colon cancer, as in breast cancer, is gene amplification...
  24. ncbi Evaluation of preoperative and postoperative radiotherapy on long-term functional results of straight coloanal anastomosis
    Daniel R Nathanson
    Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
    Dis Colon Rectum 46:888-94. 2003
    ..The deleterious effects of adjuvant radiation on long-term anorectal function can be reduced by preoperative treatment...
  25. ncbi Anastomotic leak is not associated with oncologic outcome in patients undergoing low anterior resection for rectal cancer
    James D Smith
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Ann Surg 256:1034-8. 2012
    ..To examine the association between anastomotic leak and oncologic outcome after anterior resection, stratifying for defunctioning stoma...
  26. ncbi Value of histopathology in predicting microsatellite instability in hereditary nonpolyposis colorectal cancer and sporadic colorectal cancer
    Jinru Shia
    Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10002, USA
    Am J Surg Pathol 27:1407-17. 2003
    ..Using a stepwise logistic regression model, a formula was generated that could be used to calculate the probability of a colorectal carcinoma being MSI-H based on morphologic features...
  27. ncbi Accuracy of endorectal ultrasound for measurement of the closest predicted radial mesorectal margin for rectal cancer
    P Terry Phang
    St Paul s Hospital, University of British Columbia, Vancouver, British Columbia, Canada
    Dis Colon Rectum 55:59-64. 2012
    ..Endorectal ultrasound is also used to assess the clinical stage of the cancer that will determine the recommendation for neoadjuvant chemoradiation, but it has not been used to assess the closest predicted radial margin...
  28. ncbi Long-term results of local excision for rectal cancer
    Philip B Paty
    Department of Surgery, Pathology, and Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Surg 236:522-29; discussion 529-30. 2002
    ..To review the authors' experience with local excision of early rectal cancers to assess the effectiveness of initial treatment and of salvage surgery...
  29. ncbi Insurance but not race is associated with diverticulitis mortality in a statewide database
    Vanessa P Ho
    Department of Surgery, Weill Cornell Medical College, New York, New York, USA
    Dis Colon Rectum 54:559-65. 2011
    ..We examined the association of racial identity and insurance with admission, treatment, and mortality for patients admitted to inpatient care for acute diverticulitis...