Andre L Moreira

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. pmc Advances in fine needle aspiration cytology for the diagnosis of pulmonary carcinoma
    Adnan Hasanovic
    Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Patholog Res Int 2011:897292. 2011
  2. doi request reprint Cribriform and fused glands are patterns of high-grade pulmonary adenocarcinoma
    Andre L Moreira
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA Electronic address
    Hum Pathol 45:213-20. 2014
  3. doi request reprint Molecular characterization by immunocytochemistry of lung adenocarcinoma on cytology specimens
    Andre L Moreira
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Acta Cytol 56:603-10. 2012
  4. ncbi request reprint Personalized medicine for non-small-cell lung cancer: implications of recent advances in tissue acquisition for molecular and histologic testing
    Andre L Moreira
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Clin Lung Cancer 13:334-9. 2012
  5. ncbi request reprint Progenitor stem cell marker expression by pulmonary carcinomas
    Andre L Moreira
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Mod Pathol 23:889-95. 2010
  6. doi request reprint Subtyping of non-small cell lung carcinoma: a comparison of small biopsy and cytology specimens
    Carlie S Sigel
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York City, New York 10065, USA
    J Thorac Oncol 6:1849-56. 2011
  7. pmc Distinct profile of driver mutations and clinical features in immunomarker-defined subsets of pulmonary large-cell carcinoma
    Natasha Rekhtman
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Mod Pathol 26:511-22. 2013
  8. ncbi request reprint Predicting pulmonary adenocarcinoma outcome based on a cytology grading system
    Carlie S Sigel
    1Memorial Sloan Kettering Cancer Center, Department of Pathology, New York, New York, USA
    Cancer Cytopathol 120:35-43. 2012
  9. pmc KRAS mutations are associated with solid growth pattern and tumor-infiltrating leukocytes in lung adenocarcinoma
    Natasha Rekhtman
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Mod Pathol 26:1307-19. 2013
  10. doi request reprint Suitability of thoracic cytology for new therapeutic paradigms in non-small cell lung carcinoma: high accuracy of tumor subtyping and feasibility of EGFR and KRAS molecular testing
    Natasha Rekhtman
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York City, New York 10065, USA
    J Thorac Oncol 6:451-8. 2011

Detail Information

Publications31

  1. pmc Advances in fine needle aspiration cytology for the diagnosis of pulmonary carcinoma
    Adnan Hasanovic
    Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Patholog Res Int 2011:897292. 2011
    ..In this paper we will review the current concepts in the suitability and accuracy of fine needle aspiration biopsy, including diagnosis, classification, prognostic markers, and use of ancillary techniques...
  2. doi request reprint Cribriform and fused glands are patterns of high-grade pulmonary adenocarcinoma
    Andre L Moreira
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA Electronic address
    Hum Pathol 45:213-20. 2014
    ..932) and was significantly worse than that for low- and intermediate-grade tumors (P = .0025). Complex glandular patterns have a significant prognostic value and should be considered patterns of high-grade adenocarcinoma. ..
  3. doi request reprint Molecular characterization by immunocytochemistry of lung adenocarcinoma on cytology specimens
    Andre L Moreira
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Acta Cytol 56:603-10. 2012
    ....
  4. ncbi request reprint Personalized medicine for non-small-cell lung cancer: implications of recent advances in tissue acquisition for molecular and histologic testing
    Andre L Moreira
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Clin Lung Cancer 13:334-9. 2012
    ..Recent advances in tissue acquisition techniques and specimen preservation may help to address this challenge and lead to enhanced personalized treatment in NSCLC...
  5. ncbi request reprint Progenitor stem cell marker expression by pulmonary carcinomas
    Andre L Moreira
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Mod Pathol 23:889-95. 2010
    ..Therefore, stem cell markers are expressed in lung cancers with different patterns seen for different histological types and degrees of differentiation...
  6. doi request reprint Subtyping of non-small cell lung carcinoma: a comparison of small biopsy and cytology specimens
    Carlie S Sigel
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York City, New York 10065, USA
    J Thorac Oncol 6:1849-56. 2011
    ..The relative feasibility and accuracy of NSCLC subtyping by small biopsy versus cytology is not well established, particularly in current practice where immunohistochemistry (IHC) is becoming routinely used to aid in this distinction...
  7. pmc Distinct profile of driver mutations and clinical features in immunomarker-defined subsets of pulmonary large-cell carcinoma
    Natasha Rekhtman
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Mod Pathol 26:511-22. 2013
    ..These findings have practical implications for diagnosis, predictive molecular testing and therapy selection...
  8. ncbi request reprint Predicting pulmonary adenocarcinoma outcome based on a cytology grading system
    Carlie S Sigel
    1Memorial Sloan Kettering Cancer Center, Department of Pathology, New York, New York, USA
    Cancer Cytopathol 120:35-43. 2012
    ..Therefore, we evaluated cytomorphologic features of previously histologically graded AD to identify features of potential prognostic significance...
  9. pmc KRAS mutations are associated with solid growth pattern and tumor-infiltrating leukocytes in lung adenocarcinoma
    Natasha Rekhtman
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Mod Pathol 26:1307-19. 2013
    ..Solid growth pattern was recently shown to be a strong predictor of aggressive behavior in lung adenocarcinomas, which may underlie the unfavorable prognosis associated with KRAS mutations in these tumors. ..
  10. doi request reprint Suitability of thoracic cytology for new therapeutic paradigms in non-small cell lung carcinoma: high accuracy of tumor subtyping and feasibility of EGFR and KRAS molecular testing
    Natasha Rekhtman
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York City, New York 10065, USA
    J Thorac Oncol 6:451-8. 2011
    ..The aim of this study was to comprehensively review the performance of cytologic specimens for the above two goals in a high-volume clinical practice...
  11. ncbi request reprint Immunohistochemical staining with EGFR mutation-specific antibodies: high specificity as a diagnostic marker for lung adenocarcinoma
    Yong Hannah Wen
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Mod Pathol 26:1197-203. 2013
    ..Our results show that EGFR mutation-specific antibodies could be an additional tool distinguishing primary versus metastatic carcinomas in the lung. False-positivity can be seen in breast carcinoma but is extremely rare (1%)...
  12. ncbi request reprint Histologic features are important prognostic indicators in early stages lung adenocarcinomas
    Joon Yim
    Department of Pathology, New York University School of Medicine, New York, NY, USA
    Mod Pathol 20:233-41. 2007
    ..These results are helpful in defining a subcategory of 'minimally invasive adenocarcinoma', which has features similar to bronchioloalveolar carcinoma...
  13. doi request reprint A grading system combining architectural features and mitotic count predicts recurrence in stage I lung adenocarcinoma
    Kyuichi Kadota
    Division of Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Mod Pathol 25:1117-27. 2012
    ..005) after adjusting for clinical factors. We proposed this combined architectural/mitotic grade for lung adenocarcinoma as a practical method that can be applied in routine practice...
  14. doi request reprint Immunohistochemical algorithm for differentiation of lung adenocarcinoma and squamous cell carcinoma based on large series of whole-tissue sections with validation in small specimens
    Natasha Rekhtman
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Mod Pathol 24:1348-59. 2011
    ..This simple algorithm achieves excellent accuracy in small specimens while conserving the tissue for potential predictive marker testing, which is now an essential consideration in advanced lung cancer specimens...
  15. ncbi request reprint Associations Between Mutations and Histologic Patterns of Mucin in Lung Adenocarcinoma: Invasive Mucinous Pattern and Extracellular Mucin Are Associated With KRAS Mutation
    Kyuichi Kadota
    Department of Surgery, Division of Thoracic Service Department of Medicine, Thoracic Oncology Service, Division of Solid Tumor Oncology Departments of Pathology Epidemiology and Biostatistics Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY Faculty of Medicine, Department of Diagnostic Pathology, Kagawa University, Kagawa, Japan
    Am J Surg Pathol 38:1118-27. 2014
    ..001) but not with extracellular mucin (P=0.089). Our study shows that histologic patterns of mucin in lung adenocarcinoma-including invasive mucinous adenocarcinoma and extracellular mucin-are associated with KRAS mutation. ..
  16. pmc Correlation of a priori DCE-MRI and (1)H-MRS data with molecular markers in neck nodal metastases: Initial analysis
    Jacobus F A Jansen
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Oral Oncol 48:717-22. 2012
    ..Future studies with larger patient populations need to be carried out to validate and clarify our preliminary findings...
  17. doi request reprint Primary lung adenocarcinomas in children and adolescents treated for pediatric malignancies
    Mark L Kayton
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    J Thorac Oncol 5:1764-71. 2010
    ..Herein, we present clinical, histopathologic, and molecular data on eight such cases...
  18. pmc Response to erlotinib in patients with EGFR mutant advanced non-small cell lung cancers with a squamous or squamous-like component
    Paul K Paik
    Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, 300 East 66 Street, New York, NY 10065, USA
    Mol Cancer Ther 11:2535-40. 2012
    ..These tumors can mimic SCC in small samples. We propose an approach to increase the capture of these rare histology patients for EGFR mutation testing...
  19. pmc Clarifying the spectrum of driver oncogene mutations in biomarker-verified squamous carcinoma of lung: lack of EGFR/KRAS and presence of PIK3CA/AKT1 mutations
    Natasha Rekhtman
    Department of Pathology, Thoracic Oncology Service, Department of Medicine, and Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, NY 10065, USA
    Clin Cancer Res 18:1167-76. 2012
    ....
  20. ncbi request reprint The cribriform pattern identifies a subset of acinar predominant tumors with poor prognosis in patients with stage I lung adenocarcinoma: a conceptual proposal to classify cribriform predominant tumors as a distinct histologic subtype
    Kyuichi Kadota
    1 Division of Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA 2 Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA 3 Department of Diagnostic Pathology, Faculty of Medicine, Kagawa University, Kagawa, Japan
    Mod Pathol 27:690-700. 2014
    ....
  21. doi request reprint Use of mutation specific antibodies to detect EGFR status in small biopsy and cytology specimens of lung adenocarcinoma
    Adnan Hasanovic
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Lung Cancer 77:299-305. 2012
    ..Specific antibodies that can detect mutant EGFR protein were evaluated for the detection of EGFR mutation by immunohistochemistry (IHC) in cytology and small biopsy specimens...
  22. ncbi request reprint DC-LAMP stains pulmonary adenocarcinoma with bronchiolar Clara cell differentiation
    Lee Ching Zhu
    Department of Pathology, New York University School of Medicine, NY 10016, USA
    Hum Pathol 38:260-8. 2007
    ..There was no prognostic difference in tumors that reacted with DC-LAMP. DC-LAMP and CC-10 reactivity was also observed in endometrial adenocarcinomas but not in other tumor types...
  23. ncbi request reprint A grading system of lung adenocarcinomas based on histologic pattern is predictive of disease recurrence in stage I tumors
    Gabriel Sica
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Surg Pathol 34:1155-62. 2010
    ..65 (95% confidence interval 0.57-0.73). Therefore, this scoring system provides valuable information in discriminating patients with different risk of disease-recurrence in a highly homogeneous population of patients with stage I cancer...
  24. pmc Tunneling nanotubes provide a unique conduit for intercellular transfer of cellular contents in human malignant pleural mesothelioma
    Emil Lou
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
    PLoS ONE 7:e33093. 2012
    ..We provide the first evidence of tunneling nanotubes in human primary tumors and cancer cells and propose that these structures play an important role in cancer cell pathogenesis and invasion...
  25. doi request reprint Extrauterine epithelioid trophoblastic tumors presenting as primary lung carcinomas: morphologic and immunohistochemical features to resolve a diagnostic dilemma
    Sharyn N Lewin
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Surg Pathol 33:1809-14. 2009
    ..Correlating clinical indices with specific morphologic and immunohistochemical features can ensure diagnostic accuracy and appropriate treatment for favorable outcomes...
  26. ncbi request reprint Classification of thymic epithelial neoplasms is still a challenge to thoracic pathologists: a reproducibility study using digital microscopy
    Hangjun Wang
    From the Departments of Pathology Drs Wang and Moreira, Epidemiology and Biostatistics Dr Sima, and Surgery Dr Huang, Memorial Sloan Kettering Cancer Center, New York, New York the Department of Pathology, Mount Sinai School of Medicine, New York, New York Dr Beasley the Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland Dr Illei the Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York Dr Saqi The Christie Hospital, and School of Cancer and Enabling Sciences, Department of Histopathology, University of Manchester School of Medicine, Manchester, United Kingdom Dr Nonaka and the Department of Pathology and Laboratory Medicine, University of North Carolina Chapel Hill, Chapel Hill Dr Geisinger
    Arch Pathol Lab Med 138:658-63. 2014
    ..This technology could be used to train pathologists with low-level experience in thymic epithelial tumors and to foster collaborative work in the field. ..
  27. ncbi request reprint Metastatic "borderline" papillary ovarian tumor in an intramammary lymph node
    Andre L Moreira
    Department of Pathology, New York University Medical Center, New York, New York 10016, USA
    Breast J 8:309-10. 2002
  28. pmc Dynamic contrast-enhanced magnetic resonance imaging as a predictor of outcome in head-and-neck squamous cell carcinoma patients with nodal metastases
    Amita Shukla-Dave
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Int J Radiat Oncol Biol Phys 82:1837-44. 2012
    ..The goal of this study was to assess the prognostic value of pretreatment DCE-MRI in head and neck squamous cell carcinoma (HNSCC) patients with nodal disease undergoing chemoradiation therapy or surgery...
  29. doi request reprint Cytologic diagnosis of pulmonary adenocarcinoma with micropapillary pattern: does it correlate with the histologic findings?
    Dorota E Rudomina
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Diagn Cytopathol 37:333-9. 2009
    ..Similar findings were observed for other invasive patterns. Therefore, the detection of micropapillary tufts in cytology is not specific for the diagnosis of a pulmonary micropapillary adenocarcinoma in the lung...
  30. pmc Benign mesenchymal stromal cells in human sarcomas
    Alexei Morozov
    Departments of Cell Biology, Memorial Sloan Kettering Cancer Center, New York 10065, USA
    Clin Cancer Res 16:5630-40. 2010
    ..Recent evidence suggests that at least some sarcomas arise through aberrant differentiation of mesenchymal stromal cells (MSCs), but MSCs have never been isolated directly from human sarcoma specimens...
  31. doi request reprint Failure patterns relative to radiation treatment fields for stage II-IV thymoma
    Andreas Rimner
    Departments of Radiation Oncology, Thoracic Surgery, Thoracic Oncology, Pathology, Epidemiology and Biostatistics, and Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York Departments of Radiation Oncology and Thoracic Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas and Department of Radiation Oncology, Mt Sinai Medical Center, New York, New York
    J Thorac Oncol 9:403-9. 2014
    ..Here we report the failure patterns in stage II-IV thymoma after RT at two tertiary referral centers, classified according to the new International Thymic Malignancy Interest Group definitions...