Babak J Mehrara

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. ncbi request reprint Immediate postoperative complications in DIEP versus free/muscle-sparing TRAM flaps
    Constance M Chen
    Plastic and Reconstructive Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 120:1477-82. 2007
  2. doi request reprint Surgical management of lymphedema: past, present, and future
    Babak J Mehrara
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Lymphat Res Biol 9:159-67. 2011
  3. pmc Mechanisms of lymphatic regeneration after tissue transfer
    Alan Yan
    the Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
    PLoS ONE 6:e17201. 2011
  4. pmc CD4(+) cells regulate fibrosis and lymphangiogenesis in response to lymphatic fluid stasis
    Jamie C Zampell
    the Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
    PLoS ONE 7:e49940. 2012
  5. doi request reprint p21cip/WAF is a key regulator of long-term radiation damage in mesenchyme-derived tissues
    Babak J Mehrara
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    FASEB J 24:4877-88. 2010
  6. doi request reprint Thumb reconstruction following resection for malignant tumors
    Babak J Mehrara
    Department of Surgery, Division of Orthopedic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 121:1279-87. 2008
  7. ncbi request reprint Anatomical and Surgical Concepts in Lymphatic Regeneration
    Tomer Avraham
    the Division of Plastic and Reconstructive Surgery, The Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, New York 10065, USA
    Breast J 16:639-43. 2010
  8. ncbi request reprint Complications after microvascular breast reconstruction: experience with 1195 flaps
    Babak J Mehrara
    Division of Plastic and Reconstructive Surgery and Department of Surgery, University of California, Los Angeles, Medical Center, USA
    Plast Reconstr Surg 118:1100-9; discussion 1110-1. 2006
  9. ncbi request reprint Alternative venous outflow vessels in microvascular breast reconstruction
    Babak J Mehrara
    Department of Surgery, UCLA Medical Center, Los Angeles, CA, USA
    Plast Reconstr Surg 112:448-55. 2003
  10. doi request reprint The use of a pectoralis major flap to improve internal mammary vessels exposure and reduce contour deformity in microvascular free flap breast reconstruction
    Afshin Mosahebi
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Plast Surg 61:30-4. 2008

Detail Information

Publications86

  1. ncbi request reprint Immediate postoperative complications in DIEP versus free/muscle-sparing TRAM flaps
    Constance M Chen
    Plastic and Reconstructive Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 120:1477-82. 2007
    ..This study evaluates the authors' institutional experience with immediate postoperative complications following DIEP and free/muscle-sparing TRAM flaps...
  2. doi request reprint Surgical management of lymphedema: past, present, and future
    Babak J Mehrara
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Lymphat Res Biol 9:159-67. 2011
    ..In addition, we aim to delineate the various types of surgical approaches available, indications for surgery, and reported outcomes. Our goal is to increase awareness of these options and foster research to improve their outcomes...
  3. pmc Mechanisms of lymphatic regeneration after tissue transfer
    Alan Yan
    the Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
    PLoS ONE 6:e17201. 2011
    ..The purpose of these studies was to investigate the mechanisms that regulate lymphatic regeneration after tissue transfer...
  4. pmc CD4(+) cells regulate fibrosis and lymphangiogenesis in response to lymphatic fluid stasis
    Jamie C Zampell
    the Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
    PLoS ONE 7:e49940. 2012
    ..The purpose of this study was therefore to characterize the inflammatory response to lymphatic stasis and determine if these responses are necessary for the pathological changes that occur in lymphedema...
  5. doi request reprint p21cip/WAF is a key regulator of long-term radiation damage in mesenchyme-derived tissues
    Babak J Mehrara
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    FASEB J 24:4877-88. 2010
    ..In addition, p21 is a critical regulator of MSC proliferation, differentiation, and senescence both at baseline and in response to radiation...
  6. doi request reprint Thumb reconstruction following resection for malignant tumors
    Babak J Mehrara
    Department of Surgery, Division of Orthopedic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 121:1279-87. 2008
    ..The authors report their experience with thumb reconstruction following wide excision of bone and soft-tissue tumors of the thumb...
  7. ncbi request reprint Anatomical and Surgical Concepts in Lymphatic Regeneration
    Tomer Avraham
    the Division of Plastic and Reconstructive Surgery, The Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, New York 10065, USA
    Breast J 16:639-43. 2010
    ..Operations proposed to re-establish lymphatic continuity include lymphatico-venous anastomoses, lymphatico-lymphatico anastomoses, and tissue transfer...
  8. ncbi request reprint Complications after microvascular breast reconstruction: experience with 1195 flaps
    Babak J Mehrara
    Division of Plastic and Reconstructive Surgery and Department of Surgery, University of California, Los Angeles, Medical Center, USA
    Plast Reconstr Surg 118:1100-9; discussion 1110-1. 2006
    ..This study evaluated the frequency of major and minor complications in the largest reported series of consecutive mastectomy patients treated with free tissue transfer for breast reconstruction...
  9. ncbi request reprint Alternative venous outflow vessels in microvascular breast reconstruction
    Babak J Mehrara
    Department of Surgery, UCLA Medical Center, Los Angeles, CA, USA
    Plast Reconstr Surg 112:448-55. 2003
    ..The external jugular and cephalic veins are important ancillary veins available for microvascular breast reconstruction. The dissection of these vessels is straightforward, and their use is well tolerated and highly successful...
  10. doi request reprint The use of a pectoralis major flap to improve internal mammary vessels exposure and reduce contour deformity in microvascular free flap breast reconstruction
    Afshin Mosahebi
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Plast Surg 61:30-4. 2008
    ..Resection of multiple rib segments, though unavoidable at times because of anatomic considerations, may be associated with an increased rate of postoperative contour deformities...
  11. ncbi request reprint Improving recipient vessel exposure during microvascular breast reconstruction
    Babak J Mehrara
    Division of Plastic and Reconstructive Surgery and the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Plast Surg 51:361-5. 2003
    ....
  12. ncbi request reprint Scalp reconstruction
    Babak J Mehrara
    Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Surg Oncol 94:504-8. 2006
    ..Current techniques used for scalp reconstruction after surgical ablation are the subject of this review...
  13. pmc Toll-like receptor deficiency worsens inflammation and lymphedema after lymphatic injury
    Jamie C Zampell
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Am J Physiol Cell Physiol 302:C709-19. 2012
    ..These findings suggest a role for innate immune responses, including TLR signaling, in lymphatic repair and lymphedema pathogenesis...
  14. doi request reprint Nipple-sparing mastectomy and immediate tissue expander/implant breast reconstruction
    Constance M Chen
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 124:1772-80. 2009
    ..The authors evaluated the risks and benefits of nipple- or areola-sparing mastectomy with breast reconstruction...
  15. doi request reprint TGF-beta1 is a negative regulator of lymphatic regeneration during wound repair
    Nicholas W Clavin
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Am J Physiol Heart Circ Physiol 295:H2113-27. 2008
    ..These findings imply that the clinical interventions that diminish TGF-beta1 expression may be useful in promoting more rapid lymphatic regeneration...
  16. ncbi request reprint Acellular human dermis implantation in 153 immediate two-stage tissue expander breast reconstructions: determining the incidence and significant predictors of complications
    Anuja K Antony
    Plastic and Reconstructive Surgery Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Plast Reconstr Surg 125:1606-14. 2010
    ..The purpose of this study was to evaluate the incidence of postoperative adverse events and identify significant predictors of complications in acellular human dermis tissue expander breast reconstruction...
  17. doi request reprint The use of acellular dermal matrices in two-stage expander/implant reconstruction: a multicenter, blinded, randomized controlled trial
    Colleen M McCarthy
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Plast Reconstr Surg 130:57S-66S. 2012
    ..The secondary objective was to determine whether its use would accelerate the rate of postoperative expansion...
  18. pmc HIF-1α coordinates lymphangiogenesis during wound healing and in response to inflammation
    Jamie C Zampell
    Division of Plastic and Reconstructive Surgery and Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    FASEB J 26:1027-39. 2012
    ..In summary, we show that HIF-1α is a critical coordinator of lymphangiogenesis by regulating the expression of lymphangiogenic cytokines as part of an early response mechanism to hypoxia, inflammation, and lymphatic fluid stasis...
  19. pmc Radiation therapy causes loss of dermal lymphatic vessels and interferes with lymphatic function by TGF-beta1-mediated tissue fibrosis
    Tomer Avraham
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Am J Physiol Cell Physiol 299:C589-605. 2010
    ..ASM deficiency confers LEC protection from radiation-induced apoptosis but does not prevent lymphatic dysfunction...
  20. ncbi request reprint Fibrosis is a key inhibitor of lymphatic regeneration
    Tomer Avraham
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Plast Reconstr Surg 124:438-50. 2009
    ..The purpose of these experiments was therefore to evaluate lymphatic regeneration in the setting of variable soft-tissue fibrosis...
  21. doi request reprint A nationwide analysis of the relationship between hospital volume and outcome for autologous breast reconstruction
    Claudia R Albornoz
    Plastic and Reconstructive Surgical Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Plast Reconstr Surg 132:192e-200e. 2013
    ..The volume-outcome relationship has not been specifically measured for U.S. autologous breast reconstruction. The authors studied whether there is a relationship between hospital procedural volume and perioperative complication rates...
  22. pmc Regulation of adipogenesis by lymphatic fluid stasis: part II. Expression of adipose differentiation genes
    Seth Aschen
    Divisions of Plastic and Reconstructive Surgery and Breast Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Plast Reconstr Surg 129:838-47. 2012
    ..The goal of this study was to determine how lymphatic fluid stasis regulates adipogenic gene activation and fat deposition...
  23. doi request reprint Soft-tissue coverage of the hand following sarcoma resection
    Simon G Talbot
    Plastic and Reconstructive Surgical Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 121:534-43. 2008
    ..The authors review the experience at a single institution of hand reconstruction following sarcoma resection based on prospectively collected data...
  24. doi request reprint Influence of the recipient vessel on fat necrosis after breast reconstruction with a free transverse rectus abdominis myocutaneous flap
    Nina Kropf
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Scand J Plast Reconstr Surg Hand Surg 44:96-101. 2010
    ..The exact mechanisms of this association are unknown and warrant additional investigation...
  25. doi request reprint Predicting complications following expander/implant breast reconstruction: an outcomes analysis based on preoperative clinical risk
    Colleen M McCarthy
    Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 121:1886-92. 2008
    ..This study evaluated the impact of clinical risk factors to predict complications following postmastectomy expander/implant reconstruction...
  26. doi request reprint The use of the extended anterolateral thigh flap for reconstruction of massive oncologic defects
    Afshin Mosahebi
    Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Plast Reconstr Surg 122:492-6. 2008
    ..The purpose of this report was therefore to evaluate the authors' clinical experience with the extended anterolateral thigh flap for reconstruction of oncologic defects...
  27. pmc Lymphatic function is regulated by a coordinated expression of lymphangiogenic and anti-lymphangiogenic cytokines
    Jamie C Zampell
    the Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Am J Physiol Cell Physiol 302:C392-404. 2012
    ....
  28. ncbi request reprint Free flap reexploration: indications, treatment, and outcomes in 1193 free flaps
    Duc T Bui
    Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 119:2092-100. 2007
    ..The purpose of this study was to review the authors' experience with a large number of microvascular complications over an 11-year period...
  29. doi request reprint A paradigm shift in U.S. Breast reconstruction: increasing implant rates
    Claudia R Albornoz
    From the Plastic and Reconstructive Surgical Service and the Center for Health Policy and Outcomes, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Plast Reconstr Surg 131:15-23. 2013
    ..A recent single-year report suggests significant shifts in U.S. breast reconstruction patterns. The authors' goal was to assess long-term trends in rates and types of immediate reconstruction...
  30. pmc Regulation of adipogenesis by lymphatic fluid stasis: part I. Adipogenesis, fibrosis, and inflammation
    Jamie C Zampell
    Divisions of Plastic and Reconstructive Surgery and Breast Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center
    Plast Reconstr Surg 129:825-34. 2012
    ..The goals of this two-part study were to determine the effect of lymphatic fluid stasis on adipogenesis and inflammation (part I) and how these changes regulate the temporal and spatial expression of fat differentiation genes (part II)...
  31. doi request reprint Synthesis of a tissue-engineered periosteum with acellular dermal matrix and cultured mesenchymal stem cells
    Bjorn Schonmeyr
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Tissue Eng Part A 15:1833-41. 2009
    ..In conclusion, we show that an acellular human dermis can be used to synthesize a tissue-engineered periosteum capable of delivering cells and osteoinductive proteins...
  32. ncbi request reprint Complications in smokers after postmastectomy tissue expander/implant breast reconstruction
    Susie J Goodwin
    Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Plast Surg 55:16-19; discussion 19-20. 2005
    ..Thus, smokers who undergo postmastectomy expander/implant reconstruction should be informed of the increased risk of surgical complications and should be counseled on smoking cessation...
  33. doi request reprint Economic implications of recent trends in U.S. immediate autologous breast reconstruction
    Claudia R Albornoz
    New York, N Y From the Plastic and Reconstructive Surgical Service, Memorial Sloan Kettering Cancer Center
    Plast Reconstr Surg 133:463-70. 2014
    ..This study aimed to (1) measure cost of autologous reconstruction in the setting of microsurgical technique, contralateral prophylactic mastectomies, and high-volume centers; and (2) analyze trends in market share of these procedures...
  34. ncbi request reprint Reconstruction of extremity long bone defects after sarcoma resection with vascularized fibula flaps: a 10-year review
    Constance M Chen
    Plastic and Reconstructive and Orthopedic Services, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 119:915-24; discussion 925-6. 2007
    ..Limb reconstruction has traditionally involved allografting. The authors evaluated reconstruction of extremity long bone defects after tumor resection using fibula free flaps...
  35. pmc Th2 differentiation is necessary for soft tissue fibrosis and lymphatic dysfunction resulting from lymphedema
    Tomer Avraham
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    FASEB J 27:1114-26. 2013
    ..Notably, preventing and/or reversing the development of pathological tissue changes that occur in lymphedema may be a viable treatment strategy for this disorder...
  36. doi request reprint Is the use of intraoperative heparin safe?
    Constance M Chen
    Plastic and Reconstructive Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 121:49e-53e. 2008
    ..The authors review their experience with intraoperative heparin therapy, specifically addressing the risks of hematoma, pedicle thrombosis, and flap loss rate...
  37. doi request reprint Breast cancer recurrence following prosthetic, postmastectomy reconstruction: incidence, detection, and treatment
    Colleen M McCarthy
    Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 121:381-8. 2008
    ..The purpose of this study was to evaluate the influence of prosthetic reconstruction on the incidence, detection, and management of locoregional recurrence following mastectomy for invasive breast cancer...
  38. pmc Vascular endothelial growth factor inhibits bone morphogenetic protein 2 expression in rat mesenchymal stem cells
    Björn H Schönmeyr
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Tissue Eng Part A 16:653-62. 2010
    ..The purpose of these experiments was therefore to evaluate the effect of dual transfection of these growth factors and potential mechanisms of interaction on gene expression and osteogenesis in vitro and in vivo...
  39. doi request reprint Unilateral preoperative chest wall irradiation in bilateral tissue expander breast reconstruction with acellular dermal matrix: a prospective outcomes analysis
    Katie E Weichman
    Department of Plastic Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Plast Reconstr Surg 131:921-7. 2013
    ..The authors evaluated outcomes in patients undergoing bilateral tissue expander/implant reconstruction with acellular dermal matrix in the setting of prior unilateral irradiation...
  40. doi request reprint The influence of sociodemographic factors and hospital characteristics on the method of breast reconstruction, including microsurgery: a U.S. population-based study
    Claudia R Albornoz
    Plastic and Reconstructive Surgical Service and the Center for Health Policy and Outcomes, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Plast Reconstr Surg 129:1071-9. 2012
    ..The authors studied the importance of microsurgical flaps among the techniques available for breast reconstruction and evaluated the effect of sociodemographic and hospital characteristics on the technique chosen...
  41. doi request reprint Immediate latissimus dorsi/prosthetic breast reconstruction following salvage mastectomy after failed lumpectomy/irradiation
    Joseph J Disa
    Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 121:159e-64e. 2008
    ....
  42. pmc Obesity impairs lymphatic fluid transport and dendritic cell migration to lymph nodes
    Evan S Weitman
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    PLoS ONE 8:e70703. 2013
    ..The purpose of this study was to identify the pathologic consequences of diet induced obesity (DIO) on the lymphatic system...
  43. pmc Temporal and spatial patterns of endogenous danger signal expression after wound healing and in response to lymphedema
    Jamie C Zampell
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Am J Physiol Cell Physiol 300:C1107-21. 2011
    ..01). In conclusion, HMGB1 and HSP70 are expressed along spatial gradients and upregulated in chronic lymphatic fluid stasis. Furthermore, acute expression of endogenous danger signals may play a role in inflammatory lymphangiogenesis...
  44. pmc Blockade of transforming growth factor-beta1 accelerates lymphatic regeneration during wound repair
    Tomer Avraham
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Am J Pathol 177:3202-14. 2010
    ..The use of these strategies may represent a novel means of preventing lymphedema after lymph node resection...
  45. doi request reprint Hyperbaric oxygen inhibits growth but not differentiation of normal and irradiated osteoblasts
    Alex K Wong
    Division of Plastic and Reconstructive Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pensylvania, USA
    J Craniofac Surg 19:757-65. 2008
    ..These data suggest that HBO does not have any positive effects on either normal or radiation-damaged osteoblasts in vitro...
  46. doi request reprint Reconstruction of oncologic tibial defects in children using vascularized fibula flaps
    Graham S Schwarz
    Plastic and Reconstructive Surgery Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Plast Reconstr Surg 129:195-206. 2012
    ..The authors' aim was to evaluate surgical and functional outcomes in this selected group of pediatric patients...
  47. doi request reprint Vascular complications and microvascular free flap salvage: the role of thrombolytic agents
    Eric I Chang
    UCLA Division of Plastic and Reconstructive Surgery, UCLA Medical Center, Los Angeles, CA 90095, USA
    Microsurgery 31:505-9. 2011
    ..Thrombolytic agents such as tissue plasminogen activator have been used clinically for free flap salvage in cases of pedicle thrombosis. Yet, there is a paucity of data in the literature validating the benefit of their use...
  48. doi request reprint The incidence of venous thromboembolism after oncologic head and neck reconstruction
    Constance M Chen
    Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Plast Surg 60:476-9. 2008
    ..When possible, appropriate prophylaxis against VTE in cancer patients under going head and neck reconstruction is recommended...
  49. pmc Adipose-derived stem cells promote lymphangiogenesis in response to VEGF-C stimulation or TGF-β1 inhibition
    Alan Yan
    the Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Future Oncol 7:1457-73. 2011
    ..The purpose of this study was to determine whether adipose-derived stem cells (ASCs) can be used in lymphatic tissue-engineering by altering the balance between pro- and anti-lymphangiogenic cytokines...
  50. ncbi request reprint A paradigm shift in U.S. breast reconstruction: Part 2. The influence of changing mastectomy patterns on reconstructive rate and method
    Yeliz Cemal
    Plastic and Reconstructive Surgical Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Plast Reconstr Surg 131:320e-6e. 2013
    ....
  51. doi request reprint Histologic analysis of angiogenesis and lymphangiogenesis in acellular human dermis
    Alex K Wong
    Plastic and Reconstructive Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Plast Reconstr Surg 121:1144-52. 2008
    ..The purpose of this experiment was to delineate the time course and composition of host cell infiltrate into the matrix of an AlloDerm composite flap...
  52. ncbi request reprint The pedicled latissimus dorsi flap for shoulder reconstruction after sarcoma resection
    Amir Babak Behnam
    Plastic and Reconstructive Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Ann Surg Oncol 14:1591-5. 2007
    ..This study examined a single institution's experience with the pedicled latissimus dorsi flap in reconstructing large shoulder defects after oncologic resection...
  53. ncbi request reprint Nipple-areola reconstruction following chest-wall irradiation for breast cancer: is it safe?
    Lawrence B Draper
    University of Rochester School of Medicine and Dentistry, Rochester, New York, NY 10021, USA
    Ann Plast Surg 55:12-5; discussion 15. 2005
    ..Acceptable surgical candidates demonstrate resolution of acute radiation changes, no evidence of late radiation changes, and appropriate thickness of the mastectomy skin flaps...
  54. doi request reprint Patient satisfaction with postmastectomy breast reconstruction: a comparison of saline and silicone implants
    Colleen M McCarthy
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Cancer 116:5584-91. 2010
    ..The objective of the current study was to identify predictors of patient satisfaction with breast appearance, including implant type, in a large sample of women who underwent breast reconstruction surgery using implants...
  55. ncbi request reprint Reconstruction of extensive partial or total sacrectomy defects with a transabdominal vertical rectus abdominis myocutaneous flap
    Brian S Glatt
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Plast Surg 56:526-30; discussion 530-1. 2006
    ..It has a low incidence of complications, low morbidity, and is easy to perform with a high success rate...
  56. doi request reprint Indications and outcomes for mandibular reconstruction using sequential bilateral fibula flaps
    Evan Matros
    Division of Plastic and Reconstructive Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Plast Reconstr Surg 126:1539-47. 2010
    ..The objective of this report is to describe indications and outcomes for these patients...
  57. doi request reprint Ionizing radiation of mesenchymal stem cells results in diminution of the precursor pool and limits potential for multilineage differentiation
    Björn H Schönmeyr
    Division of Plastic and Reconstructive Surgery and the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Plast Reconstr Surg 122:64-76. 2008
    ..Mesenchymal stem cells give rise to a number of tissues including bone, fat, and cartilage and provide an excellent cellular model with which to evaluate the effects of ionizing radiation on cellular survival and function...
  58. doi request reprint Tissue expander breast reconstruction is not associated with an increased risk of lymphedema
    Tomer Avraham
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Surg Oncol 17:2926-32. 2010
    ..Therefore, the purpose of this study was to determine the impact of immediate tissue expander breast reconstruction on the risk of developing lymphedema...
  59. doi request reprint Radioprotection of osteoblasts by a fractionated dose regimen and amifostine
    Alex K Wong
    Plastic and Reconstructive Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Plast Reconstr Surg 123:104S-13S. 2009
    ..To better understand the cellular mechanism of radioprotection of osseous tissue, the authors sought to determine the effect of dose fractionation and amifostine on isolated osteoblasts...
  60. ncbi request reprint Postmastectomy reconstruction: an approach to patient selection
    Joseph J Disa
    Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 124:43-52. 2009
    ....
  61. doi request reprint Microsurgical breast reconstruction
    Tomer Avraham
    Department of Surgery, The Plastic and Reconstructive Surgery Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Cancer J 14:241-7. 2008
    ..Additionally, several large series have established that microsurgical breast reconstruction has no impact on survival, or locoregional/distant recurrence rates...
  62. ncbi request reprint Outcome of split-thickness skin grafts after external beam radiotherapy
    Duc T Bui
    Plastic and Reconstructive Surgery Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Plast Surg 52:551-6; discussion 557. 2004
    ..Minor skin graft loss resulting from postoperative radiotherapy can usually be treated conservatively without the need for additional surgery...
  63. ncbi request reprint The effect of postoperative anticoagulation on microvascular thrombosis
    Peter Ashjian
    Plastic and Reconstructive Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Ann Plast Surg 59:36-9; discussion 39-40. 2007
    ..This study evaluates the rate of microvascular thrombosis in patients undergoing free-tissue transfer treated with or without antiplatelet agents...
  64. ncbi request reprint Scalp reconstruction: a 15-year experience
    Martin I Newman
    The Plastic and Reconstructive Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Plast Surg 52:501-6; discussion 506. 2004
    ..Local scalp flaps with skin grafts, and free tissue transfer remain the mainstay of reconstruction in most instances...
  65. ncbi request reprint Reconstruction of the hypopharynx with the free jejunum transfer
    Joseph J Disa
    Department of Plastic and Reconstructive Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Surg Oncol 94:466-70. 2006
    ..The most common local complications are stricture and fistula formation. A history of preoperative radiation therapy increases the risk of local complications...
  66. doi request reprint The influence of AlloDerm on expander dynamics and complications in the setting of immediate tissue expander/implant reconstruction: a matched-cohort study
    Beth Aviva Preminger
    Division of Plastic and Reconstructive Surgery, New York Presbyterian Hospital Weill Cornell Medical Center, New York, NY 10065, USA
    Ann Plast Surg 60:510-3. 2008
    ..It does not, however, appear to increase the risk of postoperative complications...
  67. ncbi request reprint Vaginal reconstruction: an algorithm approach to defect classification and flap reconstruction
    Andrea L Pusic
    Department of Plastic and Reconstructive Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Surg Oncol 94:515-21. 2006
    ..With appropriate flap choice and a multidisciplinary approach to patient care, rapid wound healing, restoration of the pelvic floor, and re-establishment of sexual function may be most reliably achieved...
  68. ncbi request reprint Use of the anterolateral thigh flap as an alternative to the rectus flap in obese and overweight patients
    Kristin Davidge
    Division of Plastic and Reconstructive Surgery and the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Plast Surg 56:536-9. 2006
    ..The purpose of this study was to evaluate our experience with the ALT flap in overweight or obese patients...
  69. ncbi request reprint Soft tissue reconstruction following tumor resection in the hand
    Simon G Talbot
    Plastic and Reconstructive Surgical Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Hand Clin 20:vi, 181-202. 2004
    ..Form, function, and cosmetic outcome influence surgical decision making, as do characteristics of the patient, tumor, and involved site...
  70. ncbi request reprint The effect of closed-suction drains on the incidence of local wound complications following tissue expander/implant reconstruction: a cohort study
    Colleen M McCarthy
    Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 119:2018-22. 2007
    ..The purpose of this investigation was to evaluate the effect of drains on complications, including infection, seroma, and hematoma formation, in patients undergoing exchange of a temporary expander for a permanent breast implant...
  71. doi request reprint Fractionated doses of ionizing radiation confer protection to mesenchymal stem cell pluripotency
    Nicholas W Clavin
    Plastic and Reconstructive Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Plast Reconstr Surg 122:739-48. 2008
    ..Thus, the purpose of this study was to assess the effects of various fractionation schedules on the growth and differentiation potential of isolated mesenchymal stem cells in vitro...
  72. doi request reprint Accelerating stem cell proliferation by down-regulation of cell cycle regulator p21
    Magdalena Plasilova
    Plastic and Reconstructive Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Plast Reconstr Surg 123:149S-57S. 2009
    ..The authors hypothesized that transient alteration in cell cycle regulators can be utilized as a means to accelerate stem cell proliferation...
  73. doi request reprint Full-thickness skin graft after nail complex resection for malignant tumors
    Mark Edward Puhaindran
    Department of Surgery, Orthopaedic Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Tech Hand Up Extrem Surg 15:84-6. 2011
    ..This technique is effective for managing melanoma in situ and early squamous cell carcinoma that affect the nail complex...
  74. doi request reprint Immediate free flap reconstruction for advanced-stage breast cancer: is it safe?
    Christopher A Crisera
    Division of Plastic and Reconstructive Surgery, University of California, Los Angeles Medical Center, Los Angeles, Calif 90095, USA
    Plast Reconstr Surg 128:32-41. 2011
    ..However, immediate breast reconstruction for advanced-stage breast cancer remains controversial. This study evaluates its safety in patients with advanced-stage breast cancer...
  75. ncbi request reprint Outcome following removal of infected tissue expanders in breast reconstruction: a 10-year experience
    Eric G Halvorson
    Plastic and Reconstructive Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Plast Surg 59:131-6. 2007
    ..Reexpansion was successful in patients without prior radiotherapy. Secondary reconstruction with autologous tissue is appropriate when there is a history of radiotherapy...
  76. ncbi request reprint Management of salivary fistulas after microvascular head and neck reconstruction
    Joshua Hyman
    Division of Plastic and Reconstructive Surgery and the Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Plast Surg 57:270-3; discussion 274. 2006
    ..The purpose of this study was, therefore, to review our experience with the management of postoperative salivary fistulas...
  77. doi request reprint Treatment of hydroxyapatite scaffolds with fibronectin and fetal calf serum increases osteoblast adhesion and proliferation in vitro
    Björn H Schönmeyr
    Division of Plastic and Reconstructive Surgery and Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Plast Reconstr Surg 121:751-62. 2008
    ..Implant compatibility may be augmented by providing cellular binding sites and by seeding cells before implantation...
  78. ncbi request reprint Reconstruction after soft tissue sarcoma resection in the setting of brachytherapy: a 10-year experience
    Hung Yi Lee
    Plastic and Reconstructive Surgery Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Plast Surg 52:486-91; discussion 492. 2004
    ..Finally, removal of closed suction drainage tubes should be deferred until after the brachytherapy catheters are removed to minimize complications resulting from catheter dislodgement...
  79. ncbi request reprint Reconstruction of complex oncologic chest wall defects: a 10-year experience
    Raymond R Chang
    Plastic and Reconstructive Surgery Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Plast Surg 52:471-9; discussion 479. 2004
    ..Based on this single institutional experience over a decade, an algorithm to chest wall reconstruction is provided...
  80. ncbi request reprint Timing of percutaneous endoscopic gastrostomy tube placement after cervical esophageal reconstruction with free jejunal transfer
    Babak J Mehrara
    Division of Plastic and Reconstructive Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Plast Surg 52:578-80. 2004
    ..Preoperative gastrostomy tube placement is not necessary in most patients unless severe preoperative nutritional compromise is present...
  81. doi request reprint Predictors of recovery of erectile function after unilateral cavernous nerve graft reconstruction at radical retropubic prostatectomy
    Farhang Rabbani
    Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Sex Med 7:166-81. 2010
    ....
  82. ncbi request reprint Use of liposuction for secondary revision of irradiated and nonirradiated free flaps
    Duc T Bui
    Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Plast Surg 52:541-5. 2004
    ..Postoperative radiation therapy is therefore not a contraindication to secondary revision. However, these procedures should be delayed for several months after the acute effects of radiation have resolved...
  83. ncbi request reprint Comparing surgical outcomes in obese women undergoing laparotomy, laparoscopy, or laparotomy with panniculectomy for the staging of uterine malignancy
    Eric L Eisenhauer
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, MRI 1026, New York, NY 10021, USA
    Ann Surg Oncol 14:2384-91. 2007
    ..The goal of this study was to compare the surgical adequacy and postoperative morbidity of three surgical approaches to staging the disease of obese women with uterine cancer...
  84. doi request reprint The effect of hyperbaric oxygen treatment on squamous cell cancer growth and tumor hypoxia
    Björn H Schönmeyr
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ann Plast Surg 60:81-8. 2008
    ..Thus, even though HBO may reduce the levels of hypoxia within squamous cell tumors, it does not appear to enhance short-term growth or promote cellular proliferation or angiogenesis...
  85. doi request reprint Anterior and middle cranial fossa skull base reconstruction using microvascular free tissue techniques: surgical complications and functional outcomes
    Ernest S Chiu
    Tulane Health Sciences Center, New Orleans, LA, USA
    Ann Plast Surg 60:514-20. 2008
    ..Early/late complications and functional problems after anterior cranial base resections are uncommon when free tissue transfer is used concomitantly...
  86. ncbi request reprint Gene therapy in plastic surgery
    Oren M Tepper
    Institute of Reconstructive Plastic Surgery and the Department of Surgery, New York University Medical Center, NY 10016, USA
    Plast Reconstr Surg 109:716-34. 2002
    ..In addition, an overview of new developments in gene therapy as they relate to plastic surgery is provided...