Jidong Liu

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. ncbi request reprint Argonaute2 is the catalytic engine of mammalian RNAi
    Jidong Liu
    Cold Spring Harbor Laboratory, Watson School of Biological Sciences, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
    Science 305:1437-41. 2004
  2. doi request reprint Control of protein synthesis and mRNA degradation by microRNAs
    Jidong Liu
    Cell Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Curr Opin Cell Biol 20:214-21. 2008
  3. pmc Mammalian GW220/TNGW1 is essential for the formation of GW/P bodies containing miRISC
    Virginia Castilla-Llorente
    Cell Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Cell Biol 198:529-44. 2012
  4. pmc MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
    Jidong Liu
    Cold Spring Harbor Laboratory, Watson School of Biological Sciences, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
    Nat Cell Biol 7:719-23. 2005
  5. pmc A role for the P-body component GW182 in microRNA function
    Jidong Liu
    Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
    Nat Cell Biol 7:1261-6. 2005
  6. ncbi request reprint Control of translation and mRNA degradation by miRNAs and siRNAs
    Marco Antonio Valencia-Sanchez
    Department of Molecular and Cellular Biology, Howard Hughes Medical Institute, University of Arizona, Tucson, Arizona 85721, USA
    Genes Dev 20:515-24. 2006
  7. pmc Jidong Liu: probing P-bodies for the secrets of silencing. Interview by Ruth Williams
    Jidong Liu
    J Cell Biol 178:894-5. 2007

Collaborators

  • ROY R PARKER
  • Scott Hammond
  • Virginia Castilla-Llorente
  • Marco Antonio Valencia-Sanchez
  • Sarah Qamar
  • Miwako Okamura
  • Saif Naseeruddin
  • Matthew Adamow
  • Lee Spraggon
  • Gregory J Hannon

Detail Information

Publications7

  1. ncbi request reprint Argonaute2 is the catalytic engine of mammalian RNAi
    Jidong Liu
    Cold Spring Harbor Laboratory, Watson School of Biological Sciences, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
    Science 305:1437-41. 2004
    ..Thus, our evidence supports a model in which Argonaute contributes "Slicer" activity to RISC, providing the catalytic engine for RNAi...
  2. doi request reprint Control of protein synthesis and mRNA degradation by microRNAs
    Jidong Liu
    Cell Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Curr Opin Cell Biol 20:214-21. 2008
    ..Although controversy remains, recent advances have shined new light on how microRNAs regulate their targets. A better understanding of the mechanism should facilitate studies of their function...
  3. pmc Mammalian GW220/TNGW1 is essential for the formation of GW/P bodies containing miRISC
    Virginia Castilla-Llorente
    Cell Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Cell Biol 198:529-44. 2012
    ..Depletion of GW220 led to the loss of GW/P bodies and destabilization of miRNA-targeted mRNA. These findings support a model in which the cellular localization of the miRISC regulates the fate of the target mRNA...
  4. pmc MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
    Jidong Liu
    Cold Spring Harbor Laboratory, Watson School of Biological Sciences, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
    Nat Cell Biol 7:719-23. 2005
    ..These results provide a link between miRNA function and mammalian P-bodies and suggest that translation repression by RISC delivers mRNAs to P-bodies, either as a cause or as a consequence of inhibiting protein synthesis...
  5. pmc A role for the P-body component GW182 in microRNA function
    Jidong Liu
    Cold Spring Harbor Laboratory, Watson School of Biological Sciences, Howard Hughes Medical Institute, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
    Nat Cell Biol 7:1261-6. 2005
    ..Thus, our results support a functional link between cytoplasmic P-bodies and the ability of a microRNA to repress expression of a target mRNA...
  6. ncbi request reprint Control of translation and mRNA degradation by miRNAs and siRNAs
    Marco Antonio Valencia-Sanchez
    Department of Molecular and Cellular Biology, Howard Hughes Medical Institute, University of Arizona, Tucson, Arizona 85721, USA
    Genes Dev 20:515-24. 2006
    ..An emerging theme is that miRNAs, and siRNAs to some extent, target mRNAs to the general eukaryotic machinery for mRNA degradation and translation control...
  7. pmc Jidong Liu: probing P-bodies for the secrets of silencing. Interview by Ruth Williams
    Jidong Liu
    J Cell Biol 178:894-5. 2007
    b>Jidong Liu tackles the many unanswered questions of RNAi.