Research Topics
| J J LewisSummaryAffiliation: Memorial Sloan-Kettering Cancer Center Country: USA Publications
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Detail Information
Publications
Multifactorial analysis of long-term follow-up (more than 5 years) of primary extremity sarcomaJ J Lewis
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Arch Surg 134:190-4. 1999..The majority of survival studies in patients with extremity soft tissue sarcoma have focused on early recurrence and mortality. There are few data addressing long-term follow-up and survival...
Effect of reresection in extremity soft tissue sarcomaJ J Lewis
Departments of Surgery, Biostatistics, and Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Surg 231:655-63. 2000..This study correlates reresection with local recurrence-free survival, metastasis-free survival, and disease-free survival...
Evaluation of CD8(+) T-cell frequencies by the Elispot assay in healthy individuals and in patients with metastatic melanoma immunized with tyrosinase peptideJ J Lewis
Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Int J Cancer 87:391-8. 2000..1/2,000 in the second patient. These results demonstrate that modest expansion of peptide-specific CD8(+) T cells can be generated in vivo by immunization with peptide plus QS-21 in at least a subset of patients with melanoma...
Soft tissue tumors of the abdominal wall: analysis of disease patterns and treatmentA Stojadinovic
Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
Arch Surg 136:70-9. 2001..Complete surgical resection is the recommended treatment approach to achieve local control. Stratification by prognostic factors will facilitate selection of patients with STS for adjuvant systemic therapies...
Characterization of molecular abnormalities in human fibroblastic neoplasms: a model for genotype-phenotype association in soft tissue tumorsA Hoos
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
Cancer Res 61:3171-5. 2001..pRB and Ki-67 status may be useful to predict recurrence in certain subsets of patients...
Synovial sarcoma: a multivariate analysis of prognostic factors in 112 patients with primary localized tumors of the extremityJ J Lewis
Departments of Surgery, Biostatistics, and Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Clin Oncol 18:2087-94. 2000..The objective of this study was to determine independent prognostic factors of primary synovial sarcoma localized to the extremity...
Clinicopathologic analysis of patients with adult rhabdomyosarcomaW G Hawkins
Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Cancer 91:794-803. 2001..All histologic subtypes of RMS are aggressive malignancies with poor disease specific survival despite aggressive multimodality management...
Sentinel lymph node biopsy in the management of patients with primary cutaneous melanoma: review of a large single-institutional experience with an emphasis on recurrenceB M Clary
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Ann Surg 233:250-8. 2001..To analyze the authors' experience with sentinel lymph node biopsy (SLNB) and the subsequent incidence and pattern of recurrence in patients with positive and negative nodes...
Soft tissue sarcomas of the groin: diagnosis, management, and prognosisA D Brooks
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
J Am Coll Surg 193:130-6. 2001..The biology of these tumors is similar to other extremity STS, and similar principles of management apply. Even with neurovascular involvement, most patients with primary groin STS do not require amputation...
Adult perineal sarcomasS R Grobmyer
Department of Surgery, Memorial-Sloan Kettering Cancer Center, New York, New York, USA
J Surg Oncol 77:101-4. 2001..CONCLUSIONS: Aggressive therapy and follow-up beginning with wide excision can be associated with long-term survival in adults with primary perineal sarcoma...
Adjuvant radiotherapy for margin-positive high-grade soft tissue sarcoma of the extremityK M Alektiar
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Int J Radiat Oncol Biol Phys 48:1051-8. 2000..The purpose of this study was to determine if adjuvant RT improves local control in patients with high-grade STS who had positive margins of resection...
Early recurrence after lymphatic mapping and sentinel node biopsy in patients with primary extremity melanoma: a comparison with elective lymph node dissectionB M Clary
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Ann Surg Oncol 8:328-37. 2001..To address this issue, we analyzed our experience with SLND and provided a comparison to patients treated with elective lymph node dissection (ELND)...
Gastrointestinal stromal tumors and leiomyosarcoma of the abdomen and retroperitoneum: a clinical comparisonB M Clary
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
Ann Surg Oncol 8:290-9. 2001..The pattern of distant spread follows the known patterns of hematogenous dissemination. Complete surgical resection is the cornerstone of treatment for primary GIST and LMS and in selected patients with local and distant recurrence...
Lymphatic mapping in the management of melanoma in childrenM S Brady
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Pediatr Dermatol 15:421-5. 1998..The use of lymphatic mapping facilitates accurate staging and identifies children in whom additional therapy may be indicated. In addition, it can assist in the assessment of the biologic potential of a difficult lesion...
Insect cells as HLA-restricted antigen-presenting cells for the IFN-gamma elispot assayS Janetzki
Swim Across America Laboratory and Departments of Surgery and Medicine, Memorial Sloan Kettering Cancer Center, New York 10021, USA
J Immunol Methods 234:1-12. 2000..Insect cells expressing human HLA molecules provide a standard APC for monitoring CD8(+) T cell responses to tumor and viral peptides during immunotherapy...
Resection of the sciatic, peroneal, or tibial nerves: assessment of functional statusA D Brooks
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
Ann Surg Oncol 9:41-7. 2002..Resection of affected sciatic nerve (branches) during limb-sparing tumor surgery is an excellent alternative to amputation...
Validation of tissue microarrays for immunohistochemical profiling of cancer specimens using the example of human fibroblastic tumorsA Hoos
Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
Am J Pathol 158:1245-51. 2001..Concordance of triplicate cores is high (96 to 98%) for two category distinction and decreases with the complexity of the phenotypes being analyzed (91%)...
Randomized, placebo-controlled trial of dietary supplementation of alpha-tocopherol on mutagen sensitivity levels in melanoma patients: a pilot trialS Mahabir
Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
Melanoma Res 12:83-90. 2002..We conclude that short term vitamin E supplementation, although it causes increased blood levels of alpha-tocopherol, does not provide protection against bleomycin-induced chromosome damage...
