Liisa Kauppi

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. ncbi request reprint Where the crossovers are: recombination distributions in mammals
    Liisa Kauppi
    Department of Genetics, University of Leicester, Leicester LE1 7RH, UK
    Nat Rev Genet 5:413-24. 2004
  2. pmc The tricky path to recombining X and Y chromosomes in meiosis
    Liisa Kauppi
    Molecular Biology Program Developmental Biology Program Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Ann N Y Acad Sci 1267:18-23. 2012
  3. ncbi request reprint Localized breakdown in linkage disequilibrium does not always predict sperm crossover hot spots in the human MHC class II region
    Liisa Kauppi
    Department of Genetics, University of Leicester, Leicester LE1 7RH, UK
    Genomics 86:13-24. 2005
  4. pmc Meiotic crossover hotspots contained in haplotype block boundaries of the mouse genome
    Liisa Kauppi
    Molecular Biology and Developmental Biology Programs, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 104:13396-401. 2007
  5. pmc Meiotic recombination hot spots and human DNA diversity
    Alec J Jeffreys
    Department of Genetics, University of Leicester, Leicester LE1 7RH, UK
    Philos Trans R Soc Lond B Biol Sci 359:141-52. 2004
  6. pmc Numerical constraints and feedback control of double-strand breaks in mouse meiosis
    Liisa Kauppi
    Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Genes Dev 27:873-86. 2013
  7. pmc Homeostatic control of recombination is implemented progressively in mouse meiosis
    Francesca Cole
    Developmental Biology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA
    Nat Cell Biol 14:424-30. 2012
  8. ncbi request reprint Recombination hotspots rather than population history dominate linkage disequilibrium in the MHC class II region
    Liisa Kauppi
    Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH, UK
    Hum Mol Genet 12:33-40. 2003
  9. doi request reprint Analysis of meiotic recombination products from human sperm
    Liisa Kauppi
    Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Methods Mol Biol 557:323-55. 2009
  10. pmc Distinct properties of the XY pseudoautosomal region crucial for male meiosis
    Liisa Kauppi
    Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Science 331:916-20. 2011

Detail Information

Publications10

  1. ncbi request reprint Where the crossovers are: recombination distributions in mammals
    Liisa Kauppi
    Department of Genetics, University of Leicester, Leicester LE1 7RH, UK
    Nat Rev Genet 5:413-24. 2004
  2. pmc The tricky path to recombining X and Y chromosomes in meiosis
    Liisa Kauppi
    Molecular Biology Program Developmental Biology Program Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Ann N Y Acad Sci 1267:18-23. 2012
    ..These findings imply that spermatocytes have evolved distinct strategies that ensure successful X-Y recombination and chromosome segregation...
  3. ncbi request reprint Localized breakdown in linkage disequilibrium does not always predict sperm crossover hot spots in the human MHC class II region
    Liisa Kauppi
    Department of Genetics, University of Leicester, Leicester LE1 7RH, UK
    Genomics 86:13-24. 2005
    ..These results highlight the complexity of LD patterns and the importance of experimentally verifying crossover hot spots...
  4. pmc Meiotic crossover hotspots contained in haplotype block boundaries of the mouse genome
    Liisa Kauppi
    Molecular Biology and Developmental Biology Programs, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 104:13396-401. 2007
    ..As increasing amounts of single-nucleotide polymorphism data emerge, this approach will be useful for investigating the recombination landscape of the mouse genome...
  5. pmc Meiotic recombination hot spots and human DNA diversity
    Alec J Jeffreys
    Department of Genetics, University of Leicester, Leicester LE1 7RH, UK
    Philos Trans R Soc Lond B Biol Sci 359:141-52. 2004
    ..These hot spots provide fundamental information on processes of human crossover and gene conversion, as well as evidence that they can violate basic rules of Mendelian inheritance...
  6. pmc Numerical constraints and feedback control of double-strand breaks in mouse meiosis
    Liisa Kauppi
    Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Genes Dev 27:873-86. 2013
    ..These findings point to the existence of a feedback mechanism that links DSB number and distribution with interhomolog interactions...
  7. pmc Homeostatic control of recombination is implemented progressively in mouse meiosis
    Francesca Cole
    Developmental Biology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA
    Nat Cell Biol 14:424-30. 2012
    ..Meiotic recombination exemplifies how order can be progressively implemented in a self-organizing system despite natural cell-to-cell disparities in the underlying biochemical processes...
  8. ncbi request reprint Recombination hotspots rather than population history dominate linkage disequilibrium in the MHC class II region
    Liisa Kauppi
    Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH, UK
    Hum Mol Genet 12:33-40. 2003
    ..Thus, while population history has some influence on LD, our findings suggest that recombination hotspots play a major global role in shaping LD patterns as well as helping to maintain localized SNP diversity in this region of the MHC...
  9. doi request reprint Analysis of meiotic recombination products from human sperm
    Liisa Kauppi
    Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Methods Mol Biol 557:323-55. 2009
    ..The centers of crossover hotspots are also active in noncrossover recombination, displaying short conversion tracts...
  10. pmc Distinct properties of the XY pseudoautosomal region crucial for male meiosis
    Liisa Kauppi
    Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Science 331:916-20. 2011
    ..Our findings uncover specific mechanisms that surmount the unique challenges of X-Y recombination...