Affiliation: Memorial Sloan-Kettering Cancer Center
- Toll-like receptor 5 stimulation protects mice from acute Clostridium difficile colitisIrene Jarchum
MImmunology Program, Department of Medicine Division of Infectious Disease, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Infect Immun 79:1498-503. 2011..difficile colitis, potentially providing an approach to prevent C. difficile-induced pathology...
- Critical role for MyD88-mediated neutrophil recruitment during Clostridium difficile colitisIrene Jarchum
Immunology Program, Sloan Kettering Institute, Infectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Infect Immun 80:2989-96. 2012..Our studies suggest that MyD88-mediated signals promote neutrophil recruitment by inducing expression of CXCL1, thereby providing critical early defense against C. difficile-mediated colitis...
- Profound alterations of intestinal microbiota following a single dose of clindamycin results in sustained susceptibility to Clostridium difficile-induced colitisCharlie G Buffie
Infectious Diseases Service, Department of Medicine, Lucille Castori Center for Microbes, Inflammation and Cancer, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Infect Immun 80:62-73. 2012..difficile infection at least 10 days following clindamycin, suggesting that resolution of diarrhea and weight gain may result from the activation of mucosal immune defenses...