Irene Jarchum

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. ncbi Toll-like receptor 5 stimulation protects mice from acute Clostridium difficile colitis
    Irene Jarchum
    MImmunology Program, Department of Medicine Division of Infectious Disease, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Infect Immun 79:1498-503. 2011
  2. ncbi Critical role for MyD88-mediated neutrophil recruitment during Clostridium difficile colitis
    Irene Jarchum
    Immunology Program, Sloan Kettering Institute, Infectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Infect Immun 80:2989-96. 2012
  3. ncbi Profound alterations of intestinal microbiota following a single dose of clindamycin results in sustained susceptibility to Clostridium difficile-induced colitis
    Charlie G Buffie
    Infectious Diseases Service, Department of Medicine, Lucille Castori Center for Microbes, Inflammation and Cancer, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Infect Immun 80:62-73. 2012

Collaborators

  • Carles Ubeda
  • Charlie G Buffie
  • Joao Xavier
  • Asia Gobourne
  • Lauren Lipuma
  • Michele Equinda
  • Agnes Viale
  • Eric G Pamer

Detail Information

Publications3

  1. ncbi Toll-like receptor 5 stimulation protects mice from acute Clostridium difficile colitis
    Irene Jarchum
    MImmunology Program, Department of Medicine Division of Infectious Disease, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Infect Immun 79:1498-503. 2011
    ..difficile colitis, potentially providing an approach to prevent C. difficile-induced pathology...
  2. ncbi Critical role for MyD88-mediated neutrophil recruitment during Clostridium difficile colitis
    Irene Jarchum
    Immunology Program, Sloan Kettering Institute, Infectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Infect Immun 80:2989-96. 2012
    ..Our studies suggest that MyD88-mediated signals promote neutrophil recruitment by inducing expression of CXCL1, thereby providing critical early defense against C. difficile-mediated colitis...
  3. ncbi Profound alterations of intestinal microbiota following a single dose of clindamycin results in sustained susceptibility to Clostridium difficile-induced colitis
    Charlie G Buffie
    Infectious Diseases Service, Department of Medicine, Lucille Castori Center for Microbes, Inflammation and Cancer, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Infect Immun 80:62-73. 2012
    ..difficile infection at least 10 days following clindamycin, suggesting that resolution of diarrhea and weight gain may result from the activation of mucosal immune defenses...