T M Hohl

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. pmc Inflammatory monocytes orchestrate innate antifungal immunity in the lung
    Vanessa Espinosa
    Rutgers, New Jersey Medical School, Department of Pediatrics, Center for Immunity and Inflammation, Newark, New Jersey, United States of America Rutgers, Graduate School of Biomedical Sciences, Newark, New Jersey, United States of America
    PLoS Pathog 10:e1003940. 2014
  2. pmc Caspofungin modulates inflammatory responses to Aspergillus fumigatus through stage-specific effects on fungal beta-glucan exposure
    T M Hohl
    Infectious Diseases Service, Memorial Sloan Kettering Cancer Center and Immunology Program, Sloan Kettering Institute, New York 10021, USA
    J Infect Dis 198:176-85. 2008
  3. pmc Aspergillus fumigatus: principles of pathogenesis and host defense
    Tobias M Hohl
    Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Eukaryot Cell 6:1953-63. 2007
  4. pmc Monocyte-mediated defense against microbial pathogens
    Natalya V Serbina
    Infectious Diseases Service, Department of Medicine, Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Annu Rev Immunol 26:421-52. 2008
  5. pmc Inflammatory monocytes facilitate adaptive CD4 T cell responses during respiratory fungal infection
    Tobias M Hohl
    Infectious Disease Service, Department of Medicine, and Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Cell Host Microbe 6:470-81. 2009
  6. pmc Monocyte trafficking to hepatic sites of bacterial infection is chemokine independent and directed by focal intercellular adhesion molecule-1 expression
    Chao Shi
    Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Immunol 184:6266-74. 2010
  7. pmc Aspergillus fumigatus triggers inflammatory responses by stage-specific beta-glucan display
    Tobias M Hohl
    Infectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    PLoS Pathog 1:e30. 2005
  8. pmc Distinct CD4+-T-cell responses to live and heat-inactivated Aspergillus fumigatus conidia
    Amariliz Rivera
    Memorial Sloan Kettering Cancer Center, Infectious Diseases Service, Immunology Program, Department of Medicine, New York, NY 10021, USA
    Infect Immun 73:7170-9. 2005
  9. pmc Essential role for neutrophils but not alveolar macrophages at early time points following Aspergillus fumigatus infection
    Monica M Mircescu
    Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, Sloan Kettering Institute, New York, New York, USA
    J Infect Dis 200:647-56. 2009
  10. pmc Selective expansion of the monocytic lineage directed by bacterial infection
    Natalya V Serbina
    Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, Immunology Program, Sloan Kettering Institute, New York, NY 10021, USA
    J Immunol 183:1900-10. 2009

Collaborators

  • ERIC G contact PAMER
  • MARTA L FELDMESSER
  • Natalya Serbina
  • Amariliz Rivera
  • Vanessa Espinosa
  • Ingrid Leiner
  • Chao Shi
  • Monica M Mircescu
  • Robert D Roorda
  • Jeffrey Rosenfeld
  • Robert Donnelly
  • Shinji Kasahara
  • Yacov Ron
  • Anupam Jhingran
  • Chiann Chyi Chen
  • Orchi Dutta
  • Peicheng Du
  • Peter Velazquez
  • Michael L Dustin
  • Nico Van Rooijen
  • Lauren Lipuma
  • Gero Miesenbock
  • Ricardo Toledo-Crow

Detail Information

Publications12

  1. pmc Inflammatory monocytes orchestrate innate antifungal immunity in the lung
    Vanessa Espinosa
    Rutgers, New Jersey Medical School, Department of Pediatrics, Center for Immunity and Inflammation, Newark, New Jersey, United States of America Rutgers, Graduate School of Biomedical Sciences, Newark, New Jersey, United States of America
    PLoS Pathog 10:e1003940. 2014
    ..Our findings illustrate both indirect and direct functions for CCR2⁺Mo and their derivatives in innate antifungal immunity in the lung...
  2. pmc Caspofungin modulates inflammatory responses to Aspergillus fumigatus through stage-specific effects on fungal beta-glucan exposure
    T M Hohl
    Infectious Diseases Service, Memorial Sloan Kettering Cancer Center and Immunology Program, Sloan Kettering Institute, New York 10021, USA
    J Infect Dis 198:176-85. 2008
    ..Our experiments demonstrate that echinocandin-induced morphological changes in A. fumigatus hyphae are accompanied by increased beta-glucan exposure, with consequent increases in Dectin-1-mediated inflammatory responses by macrophages...
  3. pmc Aspergillus fumigatus: principles of pathogenesis and host defense
    Tobias M Hohl
    Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Eukaryot Cell 6:1953-63. 2007
  4. pmc Monocyte-mediated defense against microbial pathogens
    Natalya V Serbina
    Infectious Diseases Service, Department of Medicine, Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Annu Rev Immunol 26:421-52. 2008
    ..The in vivo mechanisms that promote chemokine secretion, monocyte differentiation and trafficking, and finally monocyte-mediated microbial killing remain active and important areas of investigation...
  5. pmc Inflammatory monocytes facilitate adaptive CD4 T cell responses during respiratory fungal infection
    Tobias M Hohl
    Infectious Disease Service, Department of Medicine, and Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Cell Host Microbe 6:470-81. 2009
    ....
  6. pmc Monocyte trafficking to hepatic sites of bacterial infection is chemokine independent and directed by focal intercellular adhesion molecule-1 expression
    Chao Shi
    Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Immunol 184:6266-74. 2010
    ..monocytogenes-infected liver does not require chemokine receptor-mediated signals but instead is principally dependent on integrin- and extracellular matrix-mediated monocyte adhesion...
  7. pmc Aspergillus fumigatus triggers inflammatory responses by stage-specific beta-glucan display
    Tobias M Hohl
    Infectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    PLoS Pathog 1:e30. 2005
    ..Selective responsiveness to germinating conidia provides the innate immune system with a mechanism to restrict inflammatory responses to metabolically active, potentially invasive fungal spores...
  8. pmc Distinct CD4+-T-cell responses to live and heat-inactivated Aspergillus fumigatus conidia
    Amariliz Rivera
    Memorial Sloan Kettering Cancer Center, Infectious Diseases Service, Immunology Program, Department of Medicine, New York, NY 10021, USA
    Infect Immun 73:7170-9. 2005
    ..How the adaptive immune system distinguishes between metabolically active and inactive fungal spores remains an important question...
  9. pmc Essential role for neutrophils but not alveolar macrophages at early time points following Aspergillus fumigatus infection
    Monica M Mircescu
    Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, Sloan Kettering Institute, New York, New York, USA
    J Infect Dis 200:647-56. 2009
    ..Our studies suggest that neutrophils, but not alveolar macrophages, provide essential anticonidial defense and that a brief period of influx into the respiratory tree is sufficient to prevent conidial germination and invasive disease...
  10. pmc Selective expansion of the monocytic lineage directed by bacterial infection
    Natalya V Serbina
    Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, Immunology Program, Sloan Kettering Institute, New York, NY 10021, USA
    J Immunol 183:1900-10. 2009
    ..Our studies demonstrate that TLR-mediated signals play an essential role in the maintenance of monocyte homeostasis during systemic bacterial infection...
  11. ncbi request reprint Cracking the fungal armor
    Tobias M Hohl
    Nat Med 12:730-2. 2006
  12. ncbi request reprint Video-rate nonlinear microscopy of neuronal membrane dynamics with genetically encoded probes
    Robert D Roorda
    Laboratory of Neural Systems, Memorial Sloan Kettering Cancer Center, Box 205, 1275 York Ave, New York, NY 10021, USA
    J Neurophysiol 92:609-21. 2004
    ....