Salvador Gonzalez

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. doi request reprint Polypodium leucotomos inhibits ultraviolet B radiation-induced immunosuppression
    Jonathan R Siscovick
    Department of Dermatology, Weill Cornell Medical College, New York, NY 10021, USA
    Photodermatol Photoimmunol Photomed 24:134-41. 2008
  2. ncbi request reprint Polypodium leucotomos extract: a nutraceutical with photoprotective properties
    Salvador Gonzalez
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10022, USA
    Drugs Today (Barc) 43:475-85. 2007
  3. doi request reprint The latest on skin photoprotection
    Salvador Gonzalez
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10022, USA
    Clin Dermatol 26:614-26. 2008
  4. ncbi request reprint Confocal microscopy patterns in nonmelanoma skin cancer and clinical applications
    S Gonzalez
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY, EE UU Servicio de Dermatología, Hospital Ramon y Cajal, Madrid, España Electronic address
    Actas Dermosifiliogr 105:446-58. 2014
  5. pmc The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies
    Martina Ulrich
    Department of Dermatology, Skin Cancer Center, Charite Universitatsmedizin, Berlin, Germany
    Dermatol Pract Concept 2:202a10. 2012
  6. pmc Fernblock, a nutriceutical with photoprotective properties and potential preventive agent for skin photoaging and photoinduced skin cancers
    Salvador Gonzalez
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA Dermatology Service, Ramon y Cajal Hospital, Madrid 28034, Spain
    Int J Mol Sci 12:8466-75. 2011
  7. doi request reprint In vivo reflectance-mode confocal microscopy in clinical dermatology and cosmetology
    S Gonzalez
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10022, USA
    Int J Cosmet Sci 30:1-17. 2008
  8. ncbi request reprint [Clinical applications of reflectance confocal microscopy in the management of cutaneous tumors]
    S Gonzalez
    Servicio de Dermatología Memorial Sloan Kettering Cancer Center Nueva York Estados Unidos Servicio de Dermatología Hospiral Ramón y Cajal Madrid España
    Actas Dermosifiliogr 99:528-31. 2008
  9. ncbi request reprint Confocal reflectance microscopy in dermatology: promise and reality of non-invasive diagnosis and monitoring
    S Gonzalez
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York United States of America, Hospital Ramon y Cajal, Universidad de Alcalá de Henares Madrid
    Actas Dermosifiliogr 100:59-69. 2009
  10. doi request reprint Mechanistic insights in the use of a Polypodium leucotomos extract as an oral and topical photoprotective agent
    Salvador Gonzalez
    Dermatology Service, Memorial Sloan Kettering Cancer Center, 160 East 53rd Street, New York, NY 10022, USA
    Photochem Photobiol Sci 9:559-63. 2010

Collaborators

Detail Information

Publications59

  1. doi request reprint Polypodium leucotomos inhibits ultraviolet B radiation-induced immunosuppression
    Jonathan R Siscovick
    Department of Dermatology, Weill Cornell Medical College, New York, NY 10021, USA
    Photodermatol Photoimmunol Photomed 24:134-41. 2008
    ..UVB-induced murine skin cancers occur, in part, because of UVB-induced immunosuppression. Thus, we examined whether PL inhibits UVB-suppression of the induction of contact hypersensitivity (CHS) locally or systemically...
  2. ncbi request reprint Polypodium leucotomos extract: a nutraceutical with photoprotective properties
    Salvador Gonzalez
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10022, USA
    Drugs Today (Barc) 43:475-85. 2007
    ..Its complete loss of toxicity combined with its multifactor protection makes it a valuable tool not only for direct photoprotection, but also as an efficacious adjuvant to phototherapy of various skin diseases...
  3. doi request reprint The latest on skin photoprotection
    Salvador Gonzalez
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10022, USA
    Clin Dermatol 26:614-26. 2008
    ..The characterization of different parameters to evaluate the effects of sunscreens, such as the sunscreen protection factor, is discussed. Finally, the effect of public awareness and public health campaigns are also reviewed...
  4. ncbi request reprint Confocal microscopy patterns in nonmelanoma skin cancer and clinical applications
    S Gonzalez
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY, EE UU Servicio de Dermatología, Hospital Ramon y Cajal, Madrid, España Electronic address
    Actas Dermosifiliogr 105:446-58. 2014
    ..We explain the characteristic confocal features found in the main nonmelanoma skin tumors and discuss possible applications for this novel diagnostic technique in routine dermatology practice. ..
  5. pmc The use of reflectance confocal microscopy for monitoring response to therapy of skin malignancies
    Martina Ulrich
    Department of Dermatology, Skin Cancer Center, Charite Universitatsmedizin, Berlin, Germany
    Dermatol Pract Concept 2:202a10. 2012
    ..This article provides a very brief overview of the fundamentals of RCM and then focuses on its recent employment as a monitoring tool in skin cancer and other pathologies that may require frequent follow-up...
  6. pmc Fernblock, a nutriceutical with photoprotective properties and potential preventive agent for skin photoaging and photoinduced skin cancers
    Salvador Gonzalez
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA Dermatology Service, Ramon y Cajal Hospital, Madrid 28034, Spain
    Int J Mol Sci 12:8466-75. 2011
    ....
  7. doi request reprint In vivo reflectance-mode confocal microscopy in clinical dermatology and cosmetology
    S Gonzalez
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10022, USA
    Int J Cosmet Sci 30:1-17. 2008
    ..This review summarizes the latest advances in RCM, and its applications in the characterization of both normal and pathological skin...
  8. ncbi request reprint [Clinical applications of reflectance confocal microscopy in the management of cutaneous tumors]
    S Gonzalez
    Servicio de Dermatología Memorial Sloan Kettering Cancer Center Nueva York Estados Unidos Servicio de Dermatología Hospiral Ramón y Cajal Madrid España
    Actas Dermosifiliogr 99:528-31. 2008
    ..We also consider the limitations of the technique associated with the optical properties of the skin, with instrumentation, and with interpretation of the images...
  9. ncbi request reprint Confocal reflectance microscopy in dermatology: promise and reality of non-invasive diagnosis and monitoring
    S Gonzalez
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York United States of America, Hospital Ramon y Cajal, Universidad de Alcalá de Henares Madrid
    Actas Dermosifiliogr 100:59-69. 2009
    ..In this article, I provide an overview of RCM, including the latest technological advances as well as novel applications in the characterization of both normal and pathological skin...
  10. doi request reprint Mechanistic insights in the use of a Polypodium leucotomos extract as an oral and topical photoprotective agent
    Salvador Gonzalez
    Dermatology Service, Memorial Sloan Kettering Cancer Center, 160 East 53rd Street, New York, NY 10022, USA
    Photochem Photobiol Sci 9:559-63. 2010
    ..A striking property is that PL can exert its effect when administered orally. Together, these effects postulate PL as a natural photoprotective agent and a potential adjuvant to phototherapy for various skin diseases...
  11. ncbi request reprint Photoprotection: update in UV-filter molecules, the "new wave" of sunscreens
    S Gonzalez
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10022, USA
    G Ital Dermatol Venereol 145:515-23. 2010
    ..The last section is devoted to the newest generation of dietary photoprotective compounds. Possible mechanisms, particularly antioxidant, are discussed...
  12. ncbi request reprint Oral Polypodium leucotomos extract decreases ultraviolet-induced damage of human skin
    Maritza A Middelkamp-Hup
    Wellman Laboratories of Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Am Acad Dermatol 51:910-8. 2004
    ..Protection of skin by an oral photoprotective agent would have substantial benefits. Objective We investigated the photoprotective effect of oral administration of an extract of the natural antioxidant Polypodium leucotomos (PL)...
  13. ncbi request reprint Reflectance confocal microscopy of pigmented basal cell carcinoma
    Anna Liza Chan Agero
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10022, USA
    J Am Acad Dermatol 54:638-43. 2006
    ..Reflectance confocal microscopy (RCM) is a high-resolution imaging tool for in vivo noninvasive evaluation of skin lesions...
  14. ncbi request reprint In vivo reflectance confocal microscopy imaging of melanocytic skin lesions: consensus terminology glossary and illustrative images
    Alon Scope
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, New York 10022, USA
    J Am Acad Dermatol 57:644-58. 2007
    ..Reflectance confocal microscopy (RCM) has been used for over 10 years for in vivo skin imaging. However, to date no standard RCM terminology has been published...
  15. doi request reprint The significance of reflectance confocal microscopy in the assessment of solitary pink skin lesions
    Juliana Casagrande Tavoloni Braga
    Department of Dermatology, Memorial Sloan Kettering Cancer Center, New York, New York 10022, USA
    J Am Acad Dermatol 61:230-41. 2009
    ..The differential diagnosis for pink lesions tends, therefore, to be broad, ranging from inflammatory processes to malignancy. In vivo reflectance confocal microscopy (RCM) may help in the evaluation of pink lesions...
  16. ncbi request reprint Solar-simulated ultraviolet radiation induces abnormal maturation and defective chemotaxis of dendritic cells
    Maria Mittelbrunn
    Servicio de Inmunologia, Hospital de la Princesa Universidad Autónoma de Madrid, Madrid, Spain
    J Invest Dermatol 125:334-42. 2005
    ..These data indicate that solar-simulated UV radiation induces a defective maturation and an anomalous migratory phenotype of DC...
  17. ncbi request reprint AM3 inhibits LPS-induced iNOS expression in mice
    Pedro Majano
    Unidad de Biologia Molecular, Hospital Universitario de la Princesa, U A M, Madrid, Spain
    Int Immunopharmacol 5:1165-70. 2005
    ..Together, these results suggest that AM3 modulates the nitric oxide response and points to a possible role for AM3 in the control of the inflammatory response...
  18. ncbi request reprint Preliminary evaluation of benign vascular lesions using in vivo reflectance confocal microscopy
    Susanne Astner
    Department of Dermatology, Venerology and Allergology, Charite University Medicine, Berlin, Germany
    Dermatol Surg 36:1099-110. 2010
    ..The applicability of RCM for various neoplastic and inflammatory skin diseases has been shown, but a descriptive evaluation of different vascular lesions has not yet been performed...
  19. ncbi request reprint Detection of UV-induced pigmentary and epidermal changes over time using in vivo reflectance confocal microscopy
    Maritza A Middelkamp-Hup
    Wellman Laboratories of Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Invest Dermatol 126:402-7. 2006
    ..This technique should greatly enhance our appreciation of dynamic pigmentary changes in human or animal skin over time and in response to specific stimuli...
  20. ncbi request reprint Correlation of dermoscopy with in vivo reflectance confocal microscopy of streaks in melanocytic lesions
    Alon Scope
    Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 160 E 53rd St, New York, NY 10022, USA
    Arch Dermatol 143:727-34. 2007
    ..To analyze dermoscopically identified streaks by direct correlation with features visualized on reflectance confocal microscopy (RCM)...
  21. ncbi request reprint In vivo real-time confocal reflectance microscopy: a noninvasive guide for Mohs micrographic surgery facilitated by aluminum chloride, an excellent contrast enhancer
    Zeina Tannous
    Wellman Laboratories of Photomedicine, Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Dermatol Surg 29:839-46. 2003
    ..In vivo confocal microscopy (CM) allows noninvasive optical imaging of thin sections of living skin, in its native state, in real time, with high resolution and contrast...
  22. doi request reprint Oncogenic H-Ras and PI3K signaling can inhibit E-cadherin-dependent apoptosis and promote cell survival after photodynamic therapy in mouse keratinocytes
    Jesus Espada
    Instituto de Investigaciones Biomedicas Alberto Sols, CSIC Departamento de Bioquímica, Facultad de Medicina, Universidad Autonoma de Madrid, Madrid, Spain
    J Cell Physiol 219:84-93. 2009
    ..Taken together, these results indicate that H-Ras/PI3K/Akt signaling plays a key role in cell survival mediated by E-cadherin cell-cell contacts...
  23. ncbi request reprint Photodynamic therapy for cutaneous proliferative vascular tumors in a mouse model
    Maritza A Middelkamp-Hup
    Wellman Laboratories of Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    J Invest Dermatol 121:634-9. 2003
    ..Based on these results, we conclude that PDT-BPD can lead to selective eradication of these tumors. Further studies investigating the efficacy of PDT-BPD for human hemangiomas are warranted...
  24. ncbi request reprint Noninvasive evaluation of allergic and irritant contact dermatitis by in vivo reflectance confocal microscopy
    Susanne Astner
    Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    Dermatitis 17:182-91. 2006
    ..Reflectance-mode confocal microscopy (RCM) is an imaging technique that has previously been used to examine ACD and ICD noninvasively in vivo...
  25. doi request reprint Clinical applicability of in vivo reflectance confocal microscopy for the diagnosis of actinic keratoses
    Martina Ulrich
    Department of Dermatology, Charite University Medicine, Berlin, Germany
    Dermatol Surg 34:610-9. 2008
    ..The application of RCM for diagnosis of basal cell carcinoma has been reported; however, the evaluation of actinic keratoses (AKs) has only been the subject of preliminary studies...
  26. ncbi request reprint Pilot study on the sensitivity and specificity of in vivo reflectance confocal microscopy in the diagnosis of allergic contact dermatitis
    Susanne Astner
    Wellman Center for Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Am Acad Dermatol 53:986-92. 2005
    ..In that regard, RCM may be considered as an adjunctive tool, rather than a substitute, to clinical evaluation...
  27. ncbi request reprint In vivo reflectance-mode confocal scanning laser microscopy in dermatology
    Salvador Gonzalez
    Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Adv Dermatol 20:371-87. 2004
    ..Much like early X-ray and ultrasound imaging, RCM is in its infancy. It is only a matter of time and continued persistent research that will lead to similar success and utility for RCM...
  28. ncbi request reprint A Polypodium leucotomos extract inhibits solar-simulated radiation-induced TNF-alpha and iNOS expression, transcriptional activation and apoptosis
    Agnieska Jańczyk
    Department of Molecular Biology, Hospital de la Princesa, Madrid, Spain
    Exp Dermatol 16:823-9. 2007
    ..Together, these data postulate a multifactor mechanism of protection not exclusively reliant on the antioxidant capability of PL, and strengthen the basic knowledge on the photoprotective effect of this botanical agent...
  29. ncbi request reprint In vivo reflectance confocal microscopy of mycosis fungoides: A preliminary study
    Anna Liza C Agero
    Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10022, USA
    J Am Acad Dermatol 57:435-41. 2007
    ..Mycosis fungoides (MF) is a diagnostic challenge, frequently needing multiple and sequential biopsies to establish the diagnosis...
  30. doi request reprint Reflectance confocal microscopy of molluscum contagiosum
    Alon Scope
    Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Arch Dermatol 144:134. 2008
  31. ncbi request reprint Changing paradigms in dermatology: confocal microscopy in clinical and surgical dermatology
    Salvador Gonzalez
    Department of Dermatology, Wellman Laboratories of Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Clin Dermatol 21:359-69. 2003
    ..Being entirely non invasive, skin can be observed in its native, dynamic state. This chapter will review the fundamentals of in vivo confocal imaging and the clinical applications in general and surgical dermatology...
  32. ncbi request reprint Correlation of dermoscopic structures of melanocytic lesions to reflectance confocal microscopy
    Alon Scope
    Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10022, USA
    Arch Dermatol 143:176-85. 2007
    ..To determine the utility of reflectance confocal microscopy (RCM) in the in vivo evaluation of dermoscopic structures of melanocytic lesions...
  33. ncbi request reprint Real-time, in vivo confocal reflectance microscopy of basal cell carcinoma
    Salvador Gonzalez
    Wellman Laboratories of Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    J Am Acad Dermatol 47:869-74. 2002
    ..Real-time, near-infrared confocal laser scanning microscopy may provide a way to diagnose basal cell carcinoma in vivo and might potentially eliminate the need for invasive diagnostic biopsies in the future...
  34. ncbi request reprint Orally administered Polypodium leucotomos extract decreases psoralen-UVA-induced phototoxicity, pigmentation, and damage of human skin
    Maritza A Middelkamp-Hup
    Wellman Laboratories of Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    J Am Acad Dermatol 50:41-9. 2004
    ..The use of psoralen-UVA (PUVA) in patients of skin phototype I to II is limited by side effects of acute phototoxicity and possible long-term carcinogenesis...
  35. ncbi request reprint Use of in vivo confocal microscopy in malignant melanoma: an aid in diagnosis and assessment of surgical and nonsurgical therapeutic approaches
    Clara Curiel-Lewandrowski
    Department of Dermatology, The Cutaneous Oncology Program, and the Division of Hematology Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Arch Dermatol 140:1127-32. 2004
    ..Repeated surgical reexcisions are frequently required to achieve tumor-free margins. The use of reflectance mode confocal microscopy as an noninvasive method has shown to be a promising tool for diagnosing pigmented lesions in vivo...
  36. ncbi request reprint Evaluation of hepatic histology by near-infrared confocal microscopy: a pilot study
    Vanessa Campo-Ruiz
    Wellman Laboratories of Photomedicine, Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Hum Pathol 33:975-82. 2002
    ..This article presents a series of 12 human liver biopsy samples, providing an overview on the potential of this technique in assessing common findings from light microscopy...
  37. pmc Consistency and distribution of reflectance confocal microscopy features for diagnosis of cutaneous T cell lymphoma
    Susanne Lange-Asschenfeldt
    Universitätsmedizin Charité, Department of Dermatology, Berlin, Germany
    J Biomed Opt 17:016001. 2012
    ..Similarly, Chi(2) analysis demonstrated that selected features were present at particularly high frequency in individual skin diseases, with values ranging from 73% to 100% of all examined cases...
  38. ncbi request reprint Topical application of a protein kinase C inhibitor reduces skin and hair pigmentation
    Hee Young Park
    Department of Dermatology, Boston University School of Medicine, Massachusetts 02118, USA
    J Invest Dermatol 122:159-66. 2004
    ..These results demonstrate that inhibiting PKC activity in vivo selectively blocks tanning and reduces basal pigmentation in the epidermis and in anagen hair shafts...
  39. doi request reprint Peritumoral clefting in basal cell carcinoma: correlation of in vivo reflectance confocal microscopy and routine histology
    Martina Ulrich
    Department of Dermatology, Skin Cancer Center Charite, Charite University Medicine, Berlin, Germany
    J Cutan Pathol 38:190-5. 2011
    ....
  40. ncbi request reprint Detection of residual basal cell carcinoma by in vivo confocal microscopy
    Diego E Marra
    Department of Dermatology, Brigham and Women s Hospital, Harvard Medical School, and Mohs Surgery Center, Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Dermatol Surg 31:538-41. 2005
    ..Near-infrared reflectance-mode confocal scanning laser microscopy (RCM) represents a novel imaging technique for microscopic analysis of skin lesions and may provide a noninvasive modality for the diagnosis of basal cell carcinoma (BCC)...
  41. ncbi request reprint Detection of clinically amelanotic malignant melanoma and assessment of its margins by in vivo confocal scanning laser microscopy
    K J Busam
    Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Arch Dermatol 137:923-9. 2001
    ..Near-infrared confocal scanning laser microscopy (CSLM) represents a novel imaging technique for in vivo microscopic analysis of skin lesions, including pigmented lesions...
  42. ncbi request reprint In vivo confocal imaging of pigmented eccrine poroma
    Rieko Tachihara
    Wellman Laboratories of Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass, USA
    Dermatology 204:185-9. 2002
    ..Near-infrared reflectance confocal microscopy (CM) imaging is a noninvasive technique that can be utilized to evaluate histologic features of cutaneous lesions in vivo...
  43. ncbi request reprint Dual mode reflectance and fluorescence confocal laser scanning microscopy for in vivo imaging melanoma progression in murine skin
    Yanyun Li
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, New York 10022, USA
    J Invest Dermatol 125:798-804. 2005
    ..Combined reflectance/fluorescence in vivo confocal laser scanning microscopy holds significant promise for studies of tumor progression in murine skin...
  44. pmc Polypodium leucotomos extract decreases UV-induced Cox-2 expression and inflammation, enhances DNA repair, and decreases mutagenesis in hairless mice
    Edoardo Zattra
    Department of Dermatology, Boston University School of Medicine, MA 02118, USA
    Am J Pathol 175:1952-61. 2009
    ....
  45. ncbi request reprint Dietary lutein/zeaxanthin decreases ultraviolet B-induced epidermal hyperproliferation and acute inflammation in hairless mice
    Salvador Gonzalez
    Wellman Laboratories of Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Invest Dermatol 121:399-405. 2003
    ..01). These data demonstrate that oral supplementation of lutein and zeaxanthin diminishes the effects of ultraviolet B irradiation by reducing acute inflammatory responses and ultraviolet-induced hyperproliferative rebound...
  46. ncbi request reprint Photodynamic therapy of cancer. Basic principles and applications
    Angeles Juarranz
    Departamento de Biologia, Facultad de Ciencias, Universidad Autonoma de Madrid, Madrid, Spain
    Clin Transl Oncol 10:148-54. 2008
    ..Photofrin, ALA and its ester derivatives are the main compounds used in clinical trials, though newer and more efficient PSs are being evaluated nowadays...
  47. pmc Identification of genes responsive to solar simulated UV radiation in human monocyte-derived dendritic cells
    Hortensia de la Fuente
    Servicio de Inmunologia, Hospital de la Princesa, Universidad Autonoma de Madrid, Madrid, Spain
    PLoS ONE 4:e6735. 2009
    ..These results indicate that UV-exposure triggers the regulation of a complex gene repertoire involved in human-DC-mediated immune responses...
  48. doi request reprint In vivo UVB-photoprotective activity of extracts from commercial marine macroalgae
    Maria Guinea
    Department of Pharmacology, University of Alcala, Alcala de Henares, and Dermatology Service, Hospital Ramon y Cajal, Madrid, Spain
    Food Chem Toxicol 50:1109-17. 2012
    ..Under the assayed conditions, the extracts were safe and non-toxic to the embryos at a concentration of 0.04 mg/ml PGE...
  49. ncbi request reprint In vivo confocal microscopy in dermatology
    B Selkin
    Albany Medical Center, Albany, New York, USA
    Dermatol Clin 19:369-77, ix-x. 2001
    ..This technique recently has been used to image benign and malignant pigmented skin lesions, nonmelanoma skin cancer, inflammatory skin conditions, and dynamic skin processes...
  50. pmc AM3 modulates dendritic cell pathogen recognition capabilities by targeting DC-SIGN
    Diego Serrano-Gomez
    Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas, Madrid, Spain
    Antimicrob Agents Chemother 51:2313-23. 2007
    ..Our results indicate that DC-SIGN is the target for an immunomodulator and imply that the adjuvant and immunomodulatory actions of AM3 are mediated, at least in part, by alteration of the DC-SIGN functional activities...
  51. ncbi request reprint Irritant contact dermatitis induced by a common household irritant: a noninvasive evaluation of ethnic variability in skin response
    Susanne Astner
    Wellman Center for Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Am Acad Dermatol 54:458-65. 2006
    ..This study was undertaken to investigate the ethnic susceptibility to irritant contact dermatitis induced by a common dishwashing liquid using noninvasive technologies...
  52. ncbi request reprint Tissue engineered cartilage integration to live and devitalized cartilage: a study by reflectance mode confocal microscopy and standard histology
    Giuseppe M Peretti
    Wellman Laboratories of Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Connect Tissue Res 47:190-9. 2006
    ..Confocal microscopy provides valuable information on the integration of tissue-engineered cartilage with native tissue and could be useful for nondestructive imaging in vivo...
  53. ncbi request reprint Noninvasive imaging, treatment, and microscopic confirmation of clearance of basal cell carcinoma
    Mark Goldgeier
    Medical Advisory Board, Lucid, Inc, Rochester, New York, USA
    Dermatol Surg 29:205-10. 2003
    ..The diagnosis of basal cell carcinoma (BCC) is generally established by skin biopsy followed by tissue preparation and microscopic analysis. Treatment of BCC is often accomplished by surgical excision...
  54. ncbi request reprint Confocal microscopy oriented cryosurgery
    William Abramovits
    Int J Dermatol 41:284-5. 2002
  55. ncbi request reprint Predominant effects of Polypodium leucotomos on membrane integrity, lipid peroxidation, and expression of elastin and matrixmetalloproteinase-1 in ultraviolet radiation exposed fibroblasts, and keratinocytes
    Neena Philips
    Departments of Biology and Chemistry Biochemistry, Georgian Court College, Lakewood, NJ, USA
    J Dermatol Sci 32:1-9. 2003
    ..Exposure of skin to ultraviolet (UV) radiation can lead to deposition of excessive elastotic material, reduction in collagen, and increased expression of matrix metalloproteinases (MMPs)...
  56. ncbi request reprint Confocal reflectance imaging of head and neck surgical specimens. A comparison with histologic analysis
    W Matthew White
    Department of Otolaryngology Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
    Arch Otolaryngol Head Neck Surg 130:923-8. 2004
    ..We hypothesized that CRM is capable of discerning histologic characteristics of different tissues in the head and neck...
  57. ncbi request reprint Detectability of contrast agents for confocal reflectance imaging of skin and microcirculation
    Milind Rajadhyaksha
    Northeastern University, Center for Subsurface Sensing and Imaging Systems, 302 Stearns Center, Boston, Massachusetts 02115, USA
    J Biomed Opt 9:323-31. 2004
    ..Such analyses and experiments provide a quantitative basis for developing the opto-biochemical properties and use of contrast agents and for designing confocal instrumentation to enable real-time detectability in vivo...
  58. ncbi request reprint Regulation of the extracellular matrix remodeling by lutein in dermal fibroblasts, melanoma cells, and ultraviolet radiation exposed fibroblasts
    Neena Philips
    School of Science and Mathematics, Georgian Court University, Lakewood, NJ, USA
    Arch Dermatol Res 299:373-9. 2007
    ....
  59. ncbi request reprint Quantitative ultrasonic methods for characterization of skin lesions in vivo
    Balasundar I Raju
    Laboratory for Human and Machine Haptics, Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA
    Ultrasound Med Biol 29:825-38. 2003
    ..These results indicate that a combination of quantitative ultrasonic parameters have the potential for extracting information for characterizing skin conditions...