Affiliation: Memorial Sloan-Kettering Cancer Center
Li C, Lan Y, Schwartz Orbach L, Korol E, Tahiliani M, Evans T, et al. Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence. Cell Rep. 2015;12:1133-43 pubmed publisher
..Our results reveal essential, overlapping functions for tet genes during embryonic development and uncover a requirement for 5hmC in regulating HSC production. ..