Research Topics
Genomes and GenesSpecies | Karuna GargSummaryAffiliation: Memorial Sloan-Kettering Cancer Center Country: USA Publications
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Publications
Strategies for distinguishing low-grade endometrioid and serous carcinomas of endometriumKaruna Garg
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Adv Anat Pathol 19:1-10. 2012..We will discuss clinical, morphologic, and immunohistochemical differences between the 2 entities and provide practical tips for practicing pathologists when confronted with this differential diagnosis...
Low-grade serous neoplasms of the ovary with transformation to high-grade carcinomas: a report of 3 casesKaruna Garg
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Int J Gynecol Pathol 31:423-8. 2012..Occasional low-grade serous tumors of the ovary may transform to high-grade carcinomas, which can occur many years after initial diagnosis. The presence of a high-grade component significantly worsens patient outcomes...
Pathologic scoring of PTEN immunohistochemistry in endometrial carcinoma is highly reproducibleKaruna Garg
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Int J Gynecol Pathol 31:48-56. 2012..Our study shows that evaluation of PTEN loss by immunohistochemistry is highly reproducible with the application of standard immunohistochemical techniques and simple scoring criteria...
Morphologic features of uterine leiomyomas associated with hereditary leiomyomatosis and renal cell carcinoma syndrome: a case reportKaruna Garg
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Am J Surg Pathol 35:1235-7. 2011..Subsequent testing confirmed a fumarate hydratase mutation. The presence of above-described nuclear features in uterine leiomyomas should raise the possibility of HLRCC...
Morphologic patterns associated with BRCA1 and BRCA2 genotype in ovarian carcinomaRobert A Soslow
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Mod Pathol 25:625-36. 2012..60 (95% CI, 0.32-0.84) and a negative predictive value of 1.0 (95% CI, 0.63-1.0)). These preliminary data indicate potential strong associations between morphology and genotype in high-grade serous carcinomas...
The role of cytoreductive surgery for newly diagnosed advanced-stage uterine carcinosarcomaEdward J Tanner
Department of Surgery, Gynecology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10068, USA
Gynecol Oncol 123:548-52. 2011..The objective of this study was to assess the role of cytoreductive surgery in patients with stage IIIC-IVB uterine CS...
Endometrial carcinomas in women aged 40 years and younger: tumors associated with loss of DNA mismatch repair proteins comprise a distinct clinicopathologic subsetKaruna Garg
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Am J Surg Pathol 33:1869-77. 2009..Although young EC patients are at increased risk for synchronous endometrioid ovarian carcinomas, this does not seem to be associated with MMR loss...
Incidence of lymph node and adnexal metastasis in endometrial stromal sarcomaLisa A dos Santos
Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Gynecol Oncol 121:319-22. 2011..To determine the incidence of adnexal and lymph node (LN) metastasis in newly diagnosed endometrial stromal sarcoma (ESS)...
Endosalpingiosis in axillary lymph nodes: a possible pitfall in the staging of patients with breast carcinomaAdriana D Corben
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Am J Surg Pathol 34:1211-6. 2010..Morphologic identification of ciliated cells and "peg" cells is most helpful to recognize this benign inclusion, and positive immunoreactivity for WT1 and/or PAX8 can be used to support the diagnosis...
Endometrial and ovarian carcinomas with undifferentiated components: clinically aggressive and frequently underrecognized neoplasmsLaura J Tafe
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Mod Pathol 23:781-9. 2010..These tumors can occur in young women, may be associated with microsatellite instability and behave in a clinically aggressive manner...
High grade undifferentiated uterine sarcoma: surgery, treatment, and survival outcomesEdward J Tanner
Department of Surgery, Gynecology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Gynecol Oncol 127:27-31. 2012..Data regarding management are limited. We aimed to describe disease stage, response to treatment, and survival outcomes among patients with HGUS at our institution...
p53 overexpression in morphologically ambiguous endometrial carcinomas correlates with adverse clinical outcomesKaruna Garg
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Mod Pathol 23:80-92. 2010....
Pseudoneoplastic proliferation of histiocytes with paclitaxel-induced ultrastructural changes in a mastectomy specimenLuciano B Lemos
Department of Pathology, University of Texas Health Science Center at Houston, Medical School, Lyndon B. Johnson Hospital, Houston, TX 77026, USA
Ann Diagn Pathol 8:299-304. 2004..The treated breast carcinoma cells were tubulin-positive but the proliferating histiocytes were tubulin-negative...
Selection of endometrial carcinomas for DNA mismatch repair protein immunohistochemistry using patient age and tumor morphology enhances detection of mismatch repair abnormalitiesKaruna Garg
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Am J Surg Pathol 33:925-33. 2009..Tumor morphology (TM-MMR) along with IHC-MMR enhances the detection of EC patients at risk of HNPCC...
BRCA1 immunohistochemistry in a molecularly characterized cohort of ovarian high-grade serous carcinomasKaruna Garg
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Am J Surg Pathol 37:138-46. 2013....
Histologically bland "extremely well differentiated" thyroid carcinomas arising in struma ovarii can recur and metastasizeKaruna Garg
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Int J Gynecol Pathol 28:222-30. 2009..The hormonal milieu during pregnancy may lead to progression of malignant SO and such patients should be closely followed, particularly if their treatment consists of cystectomy alone...
Adenomatoid tumor of the adrenal gland: a clinicopathologic study of 3 casesKaruna Garg
Department of Pathology, Health Science Center, University of Texas, Houston, TX 77030-4009, USA
Ann Diagn Pathol 9:11-5. 2005..In our experience, the key to the diagnosis of this rare benign tumor is to consider adenomatoid tumor in the differential diagnosis of any glandular tumor occurring in the adrenal gland...
