Raja M Flores

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. doi Extrapleural pneumonectomy versus pleurectomy/decortication in the surgical management of malignant pleural mesothelioma: results in 663 patients
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 135:620-6, 626.e1-3. 2008
  2. pmc Video-assisted thoracic surgery (VATS) lobectomy: the evidence base
    Naveed Alam
    Peter MacCallum Cancer Centre and St Vincent s Hospital, Melbourne, Australia
    JSLS 11:368-74. 2007
  3. ncbi Positron emission tomography defines metastatic disease but not locoregional disease in patients with malignant pleural mesothelioma
    Raja M Flores
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 126:11-6. 2003
  4. ncbi Extrapleural pneumonectomy in children
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Pediatr Surg 41:1738-42. 2006
  5. ncbi Lobectomy by video-assisted thoracic surgery (VATS) versus thoracotomy for lung cancer
    Raja M Flores
    Department of Surgery, Thoracic Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 138:11-8. 2009
  6. doi The impact of lymph node station on survival in 348 patients with surgically resected malignant pleural mesothelioma: implications for revision of the American Joint Committee on Cancer staging system
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Cardiovasc Surg 136:605-10. 2008
  7. ncbi Induction chemotherapy, extrapleural pneumonectomy, and postoperative high-dose radiotherapy for locally advanced malignant pleural mesothelioma: a phase II trial
    Raja M Flores
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Oncol 1:289-95. 2006
  8. doi Video-assisted thoracic surgery lobectomy (VATS), open thoracotomy, and the robot for lung cancer
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 85:S710-5. 2008
  9. ncbi Prognostic factors in the treatment of malignant pleural mesothelioma at a large tertiary referral center
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Oncol 2:957-65. 2007
  10. ncbi Positron emission tomography predicts survival in malignant pleural mesothelioma
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Cardiovasc Surg 132:763-8. 2006

Detail Information

Publications44

  1. doi Extrapleural pneumonectomy versus pleurectomy/decortication in the surgical management of malignant pleural mesothelioma: results in 663 patients
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 135:620-6, 626.e1-3. 2008
    ..We performed a multi-institutional study to increase statistical power to detect significant differences in outcome between extrapleural pneumonectomy and pleurectomy/decortication...
  2. pmc Video-assisted thoracic surgery (VATS) lobectomy: the evidence base
    Naveed Alam
    Peter MacCallum Cancer Centre and St Vincent s Hospital, Melbourne, Australia
    JSLS 11:368-74. 2007
    ..Questions about the safety of the surgery and its adequacy as a cancer operation remain hurdles for many surgeons...
  3. ncbi Positron emission tomography defines metastatic disease but not locoregional disease in patients with malignant pleural mesothelioma
    Raja M Flores
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 126:11-6. 2003
    ..Small studies suggest that fluorodeoxyglucose-positron emission tomography may improve staging. We analyzed our experience to determine more definitively the potential utility of fluorodeoxyglucose-positron emission tomography...
  4. ncbi Extrapleural pneumonectomy in children
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Pediatr Surg 41:1738-42. 2006
    ..EPP in the pediatric population has not been reported in the literature. We report our experience of using EPP in children to treat a variety of malignancies that involve the pleural surface...
  5. ncbi Lobectomy by video-assisted thoracic surgery (VATS) versus thoracotomy for lung cancer
    Raja M Flores
    Department of Surgery, Thoracic Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 138:11-8. 2009
    ..However, a well-balanced comparison of the two procedures is lacking in the literature...
  6. doi The impact of lymph node station on survival in 348 patients with surgically resected malignant pleural mesothelioma: implications for revision of the American Joint Committee on Cancer staging system
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Cardiovasc Surg 136:605-10. 2008
    ..The American Joint Committee on Cancer staging system groups N1 and N2 disease together as stage III. The goal of this study was to define the prognostic value of specific nodal stations...
  7. ncbi Induction chemotherapy, extrapleural pneumonectomy, and postoperative high-dose radiotherapy for locally advanced malignant pleural mesothelioma: a phase II trial
    Raja M Flores
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Oncol 1:289-95. 2006
    ..We designed this clinical trial to test the feasibility of induction chemotherapy followed by EPP and RT in locally advanced MPM with the ultimate aim of improving survival...
  8. doi Video-assisted thoracic surgery lobectomy (VATS), open thoracotomy, and the robot for lung cancer
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 85:S710-5. 2008
    ..However, adequately powered well-balanced studies comparing VATS with open thoracotomy for lobectomy are lacking in the literature...
  9. ncbi Prognostic factors in the treatment of malignant pleural mesothelioma at a large tertiary referral center
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Oncol 2:957-65. 2007
    ..We conducted a large single-institution analysis to identify prognostic factors and assess the association of resection with outcome in a contemporary patient population...
  10. ncbi Positron emission tomography predicts survival in malignant pleural mesothelioma
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Thorac Cardiovasc Surg 132:763-8. 2006
    ..Because mediastinal nodal metastasis is known to be associated with poor prognosis, we hypothesized that standard uptake value on fluorodeoxyglucose positron emission tomography might independently predict survival...
  11. ncbi Induction chemotherapy, extrapleural pneumonectomy, and radiotherapy in the treatment of malignant pleural mesothelioma: the Memorial Sloan-Kettering experience
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Room C 879, New York, NY 10021, USA
    Lung Cancer 49:S71-4. 2005
    ..This experience supports additional studies of induction and multimodality therapy, especially with regimens such as cisplatin and pemetrexed which may be better tolerated and more effective...
  12. ncbi Surgical options in malignant pleural mesothelioma: extrapleural pneumonectomy or pleurectomy/decortication
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Semin Thorac Cardiovasc Surg 21:149-53. 2009
    ..The focus in stage III disease should remain on the ability to achieve macroscopic complete resection, rather than N2 disease. Patients with stage IV cancers have better survival if the lung is left in place...
  13. ncbi The role of PET in the surgical management of malignant pleural mesothelioma
    Raja M Flores
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Room C 879, New York, NY 10021, USA
    Lung Cancer 49:S27-32. 2005
    ..03). SUV of >4 and mixed histology are poor risk factors in malignant pleural mesothelioma. These findings suggest that FDG-PET can be used to stratify patients for treatment and clinical trials...
  14. doi Video-assisted thoracic surgery (VATS) lobectomy: focus on technique
    Raja M Flores
    Department of Cardiothoracic Surgery, Cornell University Medical School, New York, NY, USA
    World J Surg 34:616-20. 2010
    ..This standardized three-incision technique utilizing a 4-cm utility incision without rib spreading may allow valid comparisons of conventional procedures in clinical trials...
  15. ncbi Use of video-assisted thoracic surgery for lobectomy in the elderly results in fewer complications
    Stephen M Cattaneo
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 85:231-5; discussion 235-6. 2008
    ....
  16. ncbi Feasibility of multimodality therapy including extended resections in stage IVA thymoma
    James Huang
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Thorac Cardiovasc Surg 134:1477-83; discussion 1483-4. 2007
    ..We reviewed our experience with multimodality treatment for Masaoka stage IVA thymomas for feasibility and outcomes...
  17. ncbi Incidence and risk factors for lung injury after lung cancer resection
    Naveed Alam
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 84:1085-91; discussion 1091. 2007
    ..Our objective was to identify the incidence and risk factors for the development of postoperative lung injury...
  18. doi Patterns of recurrence and incidence of second primary tumors after lobectomy by means of video-assisted thoracoscopic surgery (VATS) versus thoracotomy for lung cancer
    Raja M Flores
    Division of Thoracic Surgery, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Thorac Cardiovasc Surg 141:59-64. 2011
    ..In response, we investigated the pattern of recurrent disease and the incidence of second primary tumors after lobectomy by means of video-assisted thoracoscopic surgery and thoracotomy...
  19. ncbi Results of chest wall resection and reconstruction with and without rigid prosthesis
    Michael J Weyant
    Department of Surgery, Thoracic Service, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 81:279-85. 2006
    ..Chest wall resections are associated with significant morbidity, with respiratory failure in as many as 27% of patients. We hypothesized that our selective use of a rigid prosthesis for reconstruction reduces respiratory complications...
  20. doi Predictors of outcomes after surgical treatment of synchronous primary lung cancers
    David J Finley
    Department of Surgery, Thoracic Service, Memorial Sloan Kettering Cancer Center, New York City, New York 10021, USA
    J Thorac Oncol 5:197-205. 2010
    ..Determining this distinction with certainty, however, is challenging. We reviewed our experience with surgical resection of presumed SPLC to analyze outcomes and identify factors associated with prolonged survival...
  21. ncbi Comparison of patterns of relapse in thymic carcinoma and thymoma
    James Huang
    Department of Surgery, Thoracic Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 138:26-31. 2009
    ..We reviewed our recent experience with the surgical management of thymic tumors and compared the outcomes and patterns of relapse between patients with thymic carcinoma and those with thymoma...
  22. doi Video-assisted thoracic surgery (VATS) evaluation of pleural effusions in patients with newly diagnosed advanced ovarian carcinoma can influence the primary management choice for these patients
    John P Diaz
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Gynecol Oncol 116:483-8. 2010
    ..To assess the utility of thoracoscopy in defining the extent of intrathoracic disease and survival outcomes in patients with moderate to large pleural effusions at the time of diagnosis of advanced ovarian carcinoma...
  23. doi Frequency of use and predictors of cancer-directed surgery in the management of malignant pleural mesothelioma in a community-based (Surveillance, Epidemiology, and End Results [SEER]) population
    Raja M Flores
    Division of Thoracic Surgery, Mount Sinai Medical Center, New York, New York 10029, USA
    J Thorac Oncol 5:1649-54. 2010
    ..This study evaluates the frequency of use and predictors of cancer-directed surgical intervention in a nontertiary-based population and the predictors for surgical intervention...
  24. doi Video-assisted thoracoscopic surgery (VATS) lobectomy: catastrophic intraoperative complications
    Raja M Flores
    Division of Thoracic Surgery, Mount Sinai School of Medicine, New York, NY, USA
    J Thorac Cardiovasc Surg 142:1412-7. 2011
    ..We reviewed our experience to determine the frequency, management, and outcome of these complications...
  25. ncbi Resection of primary mediastinal non-seminomatous germ cell tumors: a 28-year experience at memorial sloan-kettering cancer center
    Inderpal S Sarkaria
    Department of Surgery, Thoracic Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    J Thorac Oncol 6:1236-41. 2011
    ..We reviewed a single institution's operative experience with these rare tumors...
  26. ncbi The impact of video-assisted thoracic surgery (VATS) in patients with suspected advanced ovarian malignancies and pleural effusions
    Margrit M Juretzka
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Gynecol Oncol 104:670-4. 2007
    ..The objective of this study was to report the surgical findings and management of patients who underwent VATS in an update of our experience...
  27. pmc Reduction of elevated plasma osteopontin levels with resection of non-small-cell lung cancer
    Justin D Blasberg
    New York University School of Medicine, Department of Cardiothoracic Surgery, 530 First Ave, Suite 9V, New York, NY 10016 USA
    J Clin Oncol 28:936-41. 2010
    ..CONCLUSION Plasma OPN levels are elevated in early-stage NSCLC. They are reduced after resection and appear to increase with recurrence. Plasma OPN may have utility as a biomarker in early-stage NSCLC...
  28. ncbi Robotic assistance for video-assisted thoracic surgical lobectomy: technique and initial results
    Bernard J Park
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 131:54-9. 2006
    ..There is little experience with telerobotic assistance for video-assisted thoracic surgical lobectomy. We developed a technique for robotic assistance during video-assisted thoracic surgical lobectomy and report our initial results...
  29. ncbi En bloc resection of diaphragm with lung for recurrent ovarian cancer: a case report
    Lisa A dos Santos
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Gynecol Oncol 102:596-8. 2006
    ..However, direct extension of tumor into the lung is sometimes encountered, and successful resection of this type of implant has not been previously described in the gynecologic oncology literature...
  30. ncbi Mortality increases for octogenarians undergoing esophagogastrectomy for esophageal cancer
    Alexander H Moskovitz
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 82:2031-6; discussion 2036. 2006
    ..Because this risk is poorly defined, we sought to determine whether extreme age (>80 years) is an independent risk factor after esophagectomy...
  31. doi Soluble mesothelin related peptides (SMRP) and osteopontin as protein biomarkers for malignant mesothelioma: analytical validation of ELISA based assays and characterization at mRNA and protein levels
    Alex J Rai
    Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, USA
    Clin Chem Lab Med 48:271-8. 2010
    ..There is a need to identify reliable markers for malignant mesothelioma. Soluble mesothelin related peptides (SMRP) and osteopontin (OPN) have gained interest in recent years for this purpose...
  32. doi Cost comparison of robotic, video-assisted thoracic surgery and thoracotomy approaches to pulmonary lobectomy
    Bernard J Park
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Thorac Surg Clin 18:297-300, vii. 2008
    ..The average cost of VATS is substantially less than thoracotomy primarily because of a decreased length of stay. The cost of robotic assistance for VATS is still less than thoracotomy, but greater than VATS alone...
  33. doi Surgical management of tumors invading the superior vena cava
    Alejandro Garcia
    Division of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 85:2144-6. 2008
    ..We present a range of methods to approach surgical resection of tumors that have invaded the superior vena cava...
  34. ncbi Fibroepithelial polyps: preoperative diagnosis may avoid thoracotomy
    Christopher T Wartmann
    Department of Surgery, Northwestern University, Chicago, Ill, USA
    J Thorac Cardiovasc Surg 134:1080-1. 2007
  35. ncbi Endoscopic retrograde dilation of completely occlusive esophageal strictures
    Alejandro Garcia
    Division of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 82:1240-3. 2006
    ..Retrograde endoscopic lumen identification and dilation is a useful method to reestablish alimentary tract patency, thereby avoiding surgical intervention...
  36. pmc Primary myoepithelial carcinoma of the lung: a rare entity treated with parenchymal sparing resection
    Inderpal S Sarkaria
    Department of Surgery, Thoracic Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    J Cardiothorac Surg 6:27. 2011
    ..Although classified as low-grade neoplasms, these tumors have a significant rate of recurrence and distant metastasis...
  37. ncbi Aneurysm of the main pulmonary artery
    Alejandro Garcia
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Thorac Cardiovasc Surg 14:399-401. 2008
    ..We describe repair in an adult by means of graft interposition using cardiopulmonary bypass. We give our rationalization for surgical repair and present the contrary view of conservative management...
  38. ncbi Giant benign esophageal schwannoma requiring esophagectomy
    Bernard J Park
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 82:340-2. 2006
    ..All previous reports describe excision without major esophageal resection. We report the case of a 33-year-old woman with a giant esophageal schwannoma that required total thoracic esophagectomy...
  39. ncbi The benefit of video-assisted thoracoscopic surgery before planned abdominal exploration in patients with suspected advanced ovarian cancer and moderate to large pleural effusions
    Dennis S Chi
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Gynecol Oncol 94:307-11. 2004
    ..To analyze the findings and impact on the management of video-assisted thoracoscopic surgery (VATS) before planned abdominal exploration in patients with suspected advanced ovarian cancer and moderate to large pleural effusions...
  40. ncbi Imaging of pleural and chest wall tumors
    Michael J Weyant
    Cardiothoracic Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Thorac Surg Clin 14:15-23. 2004
    ..Newer imaging modalities such as PET scan and combined PET/CT might provide greater information and warrant further study in the preoperative evaluation of pleural and chest wall tumors...
  41. ncbi Aneurysmal sternal bone cyst: a novel treatment method
    Christopher T Wartmann
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 134:533-4. 2007
  42. doi Surgical treatment of malignant pleural mesothelioma
    Andrew J Kaufman
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Mount Sinai Medical Center, 1190 Fifth Avenue Box 1028, New York, NY 10029, USA
    Curr Treat Options Oncol 12:201-16. 2011
    ..Yet, despite the inherent biases in most studies, the data thus far illustrates significant survival advantages with both P/D and EPP and surgeons should consider these approaches in select patients...
  43. ncbi Full-thickness diaphragmatic resection for stage IV ovarian carcinoma using the EndoGIA stapling device followed by diaphragmatic reconstruction using a Gore-tex graft: a case report and review of the literature
    Margrit M Juretzka
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Gynecol Oncol 100:618-20. 2006
    ..Previous studies have reported the results of full-thickness diaphragmatic resection for ovarian cancer metastatic to the diaphragm...
  44. ncbi Spontaneous resolution of a pericardial cyst
    Ashkan M Abbey
    Weill Cornell Medical College, New York, NY, USA
    Ann Thorac Cardiovasc Surg 16:55-6. 2010
    ..This describes the first reported case of spontaneous pericardial cyst resolution. In select cases a conservative management may be appropriate; however, larger studies are warranted to verify these findings...