Research Topics
Genomes and GenesSpecies | Ira J DunkelSummaryAffiliation: Memorial Sloan-Kettering Cancer Center Country: USA Publications
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Publications
Risk factors for extraocular relapse following enucleation after failure of chemoreduction in retinoblastomaGuillermo L Chantada
Department of Hemato Oncology, Hospital JP Garrahan, Buenos Aires, Argentina, and Department of Pathology, University of Sao Paulo, Brazil
Pediatr Blood Cancer 49:256-60. 2007..To assess the outcome and determine risk factors for extraocular relapse in patients with retinoblastoma who had been enucleated after failure of chemoreduction...
High-dose carboplatin, thiotepa, and etoposide with autologous stem-cell rescue for patients with recurrent medulloblastoma. Children's Cancer GroupI J Dunkel
Memorial Sloan Kettering Cancer Center, New York, NY, USA
J Clin Oncol 16:222-8. 1998..Very few patients survive with conventional treatment. This study evaluated the use of high-dose carboplatin, thiotepa, and etoposide with autologous stem-cell rescue (ASCR) in patients with recurrent medulloblastoma...
Intensive multimodality therapy for patients with stage 4a metastatic retinoblastomaIra J Dunkel
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Pediatr Blood Cancer 55:55-9. 2010....
High-dose chemotherapy with autologous hematopoietic stem cell rescue for stage 4B retinoblastomaIra J Dunkel
Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Pediatr Blood Cancer 55:149-52. 2010..Here we describe a series of eight patients treated with intensive chemotherapy, defined as the intention to include high-dose chemotherapy with autologous hematopoietic stem cell rescue...
Trilateral retinoblastoma: potentially curable with intensive chemotherapyIra J Dunkel
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Pediatr Blood Cancer 54:384-7. 2010..We describe a series of 13 patients treated with intensive chemotherapy, defined as the intention to include high-dose chemotherapy with autologous hematopoietic stem cell rescue...
High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastomaIra J Dunkel
Memorial Sloan Kettering Cancer Center, Box 185, 1275 York Avenue, New York, NY 10065, USA
Neuro Oncol 12:297-303. 2010..09). This retrieval strategy provides long-term EFS for some patients with previously irradiated recurrent medulloblastoma. The use of additional RT may be associated with better outcome...
High-dose chemotherapy with autologous stem cell rescue for brain tumorsIra J Dunkel
Memorial Sloan Kettering Cancer Center, Department of Pediatrics, Box 185, 1275 York Avenue, New York, NY 10021, USA
Crit Rev Oncol Hematol 41:197-204. 2002..The role of this treatment strategy for other chemotherapy-sensitive tumors such as oligodendrogliomas and central nervous system germ cell tumors has yet to be determined...
A phase II trial of carboplatin for intraocular retinoblastomaIra J Dunkel
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Pediatr Blood Cancer 49:643-8. 2007....
Successful treatment of metastatic retinoblastomaI J Dunkel
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Cancer 89:2117-21. 2000..In the current study, the authors evaluated the use of combined intensive conventional chemotherapy, high dose chemotherapy with autologous stem cell rescue (ASCR), and radiation therapy...
Myeloablative chemotherapy with autologous bone marrow rescue in children and adolescents with recurrent malignant astrocytoma: outcome compared with conventional chemotherapy: a report from the Children's Oncology GroupJonathan L Finlay
The Children s Center for Cancer and Blood Diseases, Department of Pediatrics, Children s Hospital, Los Angeles, California 90027, USA
Pediatr Blood Cancer 51:806-11. 2008..Children and adolescents with malignant astrocytomas recurring after initial treatment have a dismal prognosis, with only rare patients surviving 1-year beyond recurrence. The purpose of this study was to attempt to improve their survival...
Brainstem primitive neuroectodermal tumors (bstPNET): results of treatment with intensive induction chemotherapy followed by consolidative chemotherapy with autologous hematopoietic cell rescueJason R Fangusaro
The Children s Hospital Los Angeles, New York University Medical Center, Memorial Sloan Kettering Cancer Center, and Schneider Children s Hospital, USA
Pediatr Blood Cancer 50:715-7. 2008..Two patients survive at least 32 months with stable disease. This approach provides an alternative for young patients with bstPNET who in prior reports have had a uniformly fatal prognosis...
Superselective ophthalmic artery chemotherapy as primary treatment for retinoblastoma (chemosurgery)David H Abramson
Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Ophthalmology 117:1623-9. 2010..To report on our 3-year experience with the use of superselective ophthalmic artery infusion of chemotherapy as initial, primary treatment for intraocular retinoblastoma...
Epstein-Barr virus-associated lymphoma in a child undergoing an autologous stem cell rescueJohn A Heath
Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
J Pediatr Hematol Oncol 24:160-3. 2002..It is concluded that EBV-LPD should be included in the differential diagnosis in patients in whom lymphadenopathy develops after autologous stem cell rescue...
ERG monitoring of retinal function during systemic chemotherapy for retinoblastomaScott E Brodie
Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Br J Ophthalmol 96:877-80. 2012..In this paper, we report ERG results for patients with retinoblastoma receiving initial treatment with systemic chemotherapy...
Subarachnoid dissemination of intraventricular tumors following simultaneous endoscopic biopsy and third ventriculostomyNeal Luther
Department of Neurological Surgery, Weill Cornell Medical College, New York, New York 10021, USA
J Neurosurg Pediatr 5:61-7. 2010..The aim of this study was to ascertain the rate of leptomeningeal dissemination following this surgical procedure...
Persistence of retinal function after selective ophthalmic artery chemotherapy infusion for retinoblastomaScott E Brodie
Memorial Sloan Kettering Cancer Center, New York, NY, USA
Doc Ophthalmol 119:13-22. 2009..To assess potential retinal viability by electroretinography following selective ophthalmic artery chemotherapy infusion for retinoblastoma...
Three-drug intra-arterial chemotherapy using simultaneous carboplatin, topotecan and melphalan for intraocular retinoblastoma: preliminary resultsBrian P Marr
Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Br J Ophthalmol 96:1300-3. 2012..To report outcomes with selective intra-arterial chemotherapy (SIAC) using simultaneous carboplatin, topotecan, and melphalan for advanced intraocular retinoblastoma...
Success of intra-arterial chemotherapy (chemosurgery) for retinoblastoma: effect of orbitovascular anatomyBrian P Marr
Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Arch Ophthalmol 130:180-5. 2012....
Thiotepa/topotecan/carboplatin with autologous stem cell rescue in recurrent/refractory/poor prognosis pediatric malignancies of the central nervous systemStephen W Gilheeney
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Pediatr Blood Cancer 54:591-5. 2010..We present ten patients with recurrent or progressive central nervous system malignancies treated on a myeloablative regimen using these drugs...
Thiotepa-based high-dose chemotherapy with autologous stem-cell rescue in patients with recurrent or progressive CNS germ cell tumorsShakeel Modak
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Clin Oncol 22:1934-43. 2004..To evaluate the efficacy and toxicity of high-dose chemotherapy (HDC) followed by autologous stem-cell rescue (ASCR) in patients with relapsed or progressive CNS germ cell tumors (GCTs)...
Disease control and ototoxicity using intensity-modulated radiation therapy tumor-bed boost for medulloblastomaWilliam R Polkinghorn
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Int J Radiat Oncol Biol Phys 81:e15-20. 2011..In order to decrease ototoxicity, we subsequently implemented a tumor-bed boost using intensity-modulated radiation therapy (IMRT), the clinical results of which we report here...
The prognostic value of tumor markers in newly diagnosed patients with primary central nervous system germ cell tumorsAerang Kim
New York University Medical Center, New York, New York, USA
Pediatr Blood Cancer 51:768-73. 2008....
High-dose chemotherapy with autologous stem-cell rescue in the treatment of patients with recurrent non-cerebellar primitive neuroectodermal tumorsAlberto Broniscer
Children's Cancer Group: New York University Medical Center, New York, NY, USA
Pediatr Blood Cancer 42:261-7. 2004..006 and 0.01, respectively). CONCLUSIONS: Patients with recurrent cortical PNETs can be cured with this strategy. Surgical debulking before, and irradiation after HDC play an important role in treatment success...
Long-term medical outcomes in survivors of extra-ocular retinoblastoma: the Memorial Sloan-Kettering Cancer Center (MSKCC) experienceDanielle Novetsky Friedman
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Pediatr Blood Cancer 60:694-9. 2013..Data on long-term outcomes of survivors of extra-ocular retinoblastoma are lacking. The authors sought to provide the first report characterizing long-term outcomes among survivors of extra-ocular retinoblastoma...
Intra-arterial chemotherapy for retinoblastoma in eyes with vitreous and/or subretinal seeding: 2-year resultsDavid H Abramson
Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Br J Ophthalmol 96:499-502. 2012..To review the effectiveness of intra-arterial chemotherapy for advanced intra-ocular retinoblastoma with vitreous and/or subretinal seeds in naive (untreated) and previously treated eyes...
Intra-arterial chemotherapy for the management of retinoblastoma: four-year experienceY Pierre Gobin
Interventional Neuroradiology, Departments of Radiology and Neurosurgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10065, USA
Arch Ophthalmol 129:732-7. 2011..Retinoblastoma often presents with advanced intraocular disease and, despite conventional treatment with intravenous chemotherapy and external beam radiation therapy, may still require enucleation...
Ophthalmic artery chemosurgery for the management of retinoblastoma in eyes with extensive (>50%) retinal detachmentSotiria Palioura
Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Pediatr Blood Cancer 59:859-64. 2012..e. ophthalmic artery chemosurgery, has been used for the treatment of advanced intraocular retinoblastoma. Herein, we evaluate the efficacy of ophthalmic artery chemosurgery for retinoblastoma associated with >50% retinal detachment...
Periocular carboplatin for retinoblastoma: long-term report (12 years) on efficacy and toxicityBrian P Marr
Department of Surgery, Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, 70 East 66th Street, New York, NY 10065, USA
Br J Ophthalmol 96:881-3. 2012..To report the experience of the authors with efficacy and toxicity of periocular chemotherapy over a 12-year period...
Outcome following initial external beam radiotherapy in patients with Reese-Ellsworth group Vb retinoblastomaDavid H Abramson
Department of Ophthalmology, New York Presbyterian Hospital-Weill Medical College of Cornell University, 70 E. 66th Street, New York, NY 10021, USA
Arch Ophthalmol 122:1316-23. 2004..Outcome data provided herein are clinically relevant when choosing treatment options for advanced intraocular retinoblastoma...
Intra-arterial and oral digoxin therapy for retinoblastomaMrinali Patel
Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, USA
Ophthalmic Genet 32:147-50. 2011..Preclinical studies demonstrate that cardiac glycosides such as ouabain and digoxin have antitumor effects on retinoblastoma cells in vitro and in a xenograft murine model of retinoblastoma...
Patterns of failure using a conformal radiation therapy tumor bed boost for medulloblastomaSuzanne L Wolden
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Box 22, New York, NY 10021, USA
J Clin Oncol 21:3079-83. 2003..To assess the patterns of failure for patients with medulloblastoma receiving a conformal tumor bed boost rather than a boost to the entire posterior fossa...
Primary leptomeningeal primitive neuroectodermal tumorMartin Begemann
Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Neurooncol 63:299-303. 2003..After the initial presentation of 3.5 years the boy began to suffer from prolonged refractory non-convulsive status epilepticus and later expired from progression of primary leptomeningeal PNET...
Preliminary results of dose intensive pre-irradiation chemotherapy in patients older than 10 years of age with high risk medulloblastoma and supratentorial primitive neuroectodermal tumorsKavita Dhodapkar
New York University Medical Center, New York, NY, USA
Med Pediatr Oncol 38:47-8. 2002
Combined, sequential intravenous and intra-arterial chemotherapy (bridge chemotherapy) for young infants with retinoblastomaY Pierre Gobin
Service of Interventional Neuroradiology, Department of Neurosurgery, Weill Cornell Medical College of New York Presbyterian Hospital, New York, New York, United States of America
PLoS ONE 7:e44322. 2012..a.) chemotherapy has more risks of procedural complications in neonates and young infants. For these reasons, we have developed a strategy of bridge intravenous single agent chemotherapy to postpone i.a. chemotherapy in these children..
New retinoblastoma tumor formation in children initially treated with systemic carboplatinThomas C Lee
Department of Ophthalmology, New York-Presbyterian Hospital-Weill Medical College of Cornell University, 70 East 66th Street, New York, NY 10021, USA
Ophthalmology 110:1989-94; discussion 1994-5. 2003..0182). CONCLUSIONS: New intraocular tumors continue to develop after systemic carboplatin; most new tumors appeared within 4 months of treatment...
Reirradiation for recurrent medulloblastomaRichard L Bakst
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Cancer 117:4977-82. 2011..Reirradiation is often not considered secondary to its potential toxicity and uncertain efficacy. Analysis of retreatment could help identify the feasibility and role of reirradiation for recurrent MB...
Myeloablative chemotherapy with autologous bone marrow rescue in young children with recurrent malignant brain tumorsS Guruangan
Memorial Sloan Kettering Cancer Center, New York, NY, USA
J Clin Oncol 16:2486-93. 1998....
Published international classification of retinoblastoma (ICRB) definitions contain inconsistencies--an analysis of impactDanielle E Novetsky
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ophthalmic Genet 30:40-4. 2009..To determine the impact of subtle differences (most notably in their classification of group E eyes) in two published versions of the ICRB (Philadelphia and the Children's Hospital Los Angeles)...
Lack of activity of oral etoposide for relapsed intraocular retinoblastomaIra J Dunkel
Department of Pediatrics, Memorial-Sloan Kettering Cancer Center, New York, NY, USA
Ophthalmic Genet 25:25-9. 2004..CONCLUSIONS: Oral etoposide was not an effective agent in this population. The role of etoposide in the treatment of higher risk intraocular retinoblastoma deserves further study...
Phase I study of targeted radioimmunotherapy for leptomeningeal cancers using intra-Ommaya 131-I-3F8Kim Kramer
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Clin Oncol 25:5465-70. 2007..We tested the toxicity, pharmacokinetics, and dosimetry of intraventricular iodine-131-labeled monoclonal antibody 3F8 (131I-3F8) targeting GD2-positive CNS/LM disease in a phase I clinical trial...
Current management strategies for intraocular retinoblastomaJonathan W Kim
Department of Ophthalmic Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Drugs 67:2173-85. 2007..Therefore, modern centres treating retinoblastoma continue to manage patients with a variety of modalities, individualising the therapy according to the patient's presentation and clinical course...
Intraparenchymal and intratumoral interstitial infusion of anti-glioma monoclonal antibody 8H9Neal Luther
Department of Neurological Surgery, Weill Cornell Medical College, New York, New York 10021, USA
Neurosurgery 63:1166-74; discussion 1174. 2008..Interstitial delivery of murine immunoglobulin G1 monoclonal antibody (MAb) 8H9 was investigated in a rodent model for the potential treatment of infiltrative gliomas...
Novel use of zolpidem in cerebellar mutism syndromeCharles Shyu
Department of Neurology, University of Illinois at Urban Champaign, New York, NY 10065, USA
J Pediatr Hematol Oncol 33:148-9. 2011..Our report suggests that clinicians should consider using zolpidem for patients with CMS...
Intraocular hemorrhage after intra-arterial chemotherapy for retinoblastoma in sickle cell traitDavid H Abramson
Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, USA
Open Ophthalmol J 6:1-3. 2012..Clinicians should be on the lookout for the association of sickle-cell disease/trait and intraocular hemorrhages after intraarterial chemotherapy to fully understand its clinical significance...
Intraoperative arachnoid and cerebrospinal fluid sampling in children with posterior fossa brain tumorsMark M Souweidane
Department of Neurological Surgery, Weill Cornell Medical College, and Memorial Sloan Kettering Cancer Center, New York, New York, USA
Neurosurgery 65:72-8; discussion 78. 2009..This study was conducted to determine whether arachnoid tissue or cerebrospinal fluid (CSF) sampling is valuable for risk stratification in children with posterior fossa brain tumors...
Impairments in antifolate transport are common in retinoblastoma tumor samplesRichard G Gorlick
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Pediatr Blood Cancer 50:573-6. 2008..Identification of effective chemotherapy agents for retinoblastoma that are not associated with an elevated risk of secondary malignancy would be beneficial...
A phase I/II study of direct intraarterial (ophthalmic artery) chemotherapy with melphalan for intraocular retinoblastoma initial resultsDavid H Abramson
Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ophthalmology 115:1398-404, 1404.e1. 2008....
Topotecan combined with myeloablative doses of thiotepa and carboplatin for neuroblastoma, brain tumors, and other poor-risk solid tumors in children and young adultsB H Kushner
Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
Bone Marrow Transplant 28:551-6. 2001....
Quality of life and behavioral follow-up study of Head Start I pediatric brain tumor survivorsStephen A Sands
Departments of Pediatrics and Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
J Neurooncol 101:287-95. 2011....
More aggressive bone marrow screening in retinoblastoma patients is not indicated: the memorial Sloan-Kettering cancer center experienceStergios Zacharoulis
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Pediatr Blood Cancer 46:56-61. 2006....
Sinonasal adenocarcinoma: a rare second malignancy in long term retinoblastoma survivorsPooja Bhagia
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Pediatr Blood Cancer 57:693-5. 2011..Sinonasal adenocarcinoma should be considered as a second malignancy in retinoblastoma survivors who present with vague sinus symptoms...
Correlation of endoscopic biopsy with tumor marker status in primary intracranial germ cell tumorsNeal Luther
Department of Neurological Surgery, Weill Medical College of Cornell University, New York, NY, USA
J Neurooncol 79:45-50. 2006..We would thus conclude that when primary germ cell tumor is considered, endoscopic tumor biopsy is recommended in patients with a negative biochemical analysis, but not suggested for patients presenting with elevated tumor markers...
A phase II trial of thalidomide and cyclophosphamide in patients with recurrent or refractory pediatric malignanciesStephen W Gilheeney
Departments of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Pediatr Blood Cancer 49:261-5. 2007..This trial was undertaken to investigate whether the combination of cyclophosphamide and thalidomide would be active against pediatric tumors...
Sclerosing epithelioid fibrosarcomas involving the neuraxis: report of three casesM H Bilsky
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Neurosurgery 47:956-9; discussion 959-60. 2000..A single instance of brain and vertebral metastasis has been described. We report three examples of SEF distinguished by primary involvement of the neuraxis at initial presentation...
Targeted radioimmunotherapy for leptomeningeal cancer using (131)I-3F8K Kramer
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Med Pediatr Oncol 35:716-8. 2000..Intrathecal antibody-based targeted therapies may have clinical potential for patients with leptomeningeal (LM) cancer...
Delayed diagnosis of retinoblastoma: analysis of degree, cause, and potential consequencesLinda J Butros
Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
Pediatrics 109:E45. 2002....
Recurrent ependymoma treated with high-dose tamoxifen in a peripubertal female: Impact on tumor and the pituitary-ovarian axisRona Yoffe
Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
Pediatr Blood Cancer 49:758-60. 2007..However, treatment with tamoxifen resulted in the development of large ovarian cysts associated with supraphysiological plasma concentrations of estradiol...
Intraventricular meningioma after cranial irradiation for childhood leukemiaDouglas E Ney
Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
J Child Neurol 25:1292-5. 2010..Radiation-induced meningiomas may also have predilection to recur. The authors describe a case of an intraventricular meningioma occurring 23 years after cranial irradiation for childhood acute lymphoblastic leukemia...
Systemic carboplatin for retinoblastoma: change in tumour size over timeD H Abramson
70 East 66th Street, New York, NY 10021, USA
Br J Ophthalmol 89:1616-9. 2005..Quantitative data regarding retinal tumour response following treatment with primary systemic carboplatin are reported...
Spontaneously Resolving Periocular Erythema and Ciliary Madarosis Following Intra-arterial Chemotherapy for RetinoblastomaBrian Marr
Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Middle East Afr J Ophthalmol 17:207-9. 2010..To describe an unusual clinical finding seen in children undergoing intra-arterial chemotherapy for retinoblastoma...
Histopathologic findings of eyes enucleated after treatment with chemosurgery for retinoblastomaCarolyn P Graeber
Memorial Sloan Kettering Cancer Center, New York, NY, USA
Open Ophthalmol J 5:1-5. 2011..MATERIALS AND METHODOLOGY: Independent histopathologic review of the enucleated eyes was correlated with the clinical findings that prompted enucleation...
Vancomycin-resistant enterococcus in pediatric oncology patients: An analysis of potential consequences of colonization and infectionAmanda Kosack
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Pediatr Blood Cancer 52:300-2. 2009..None of the hypothesized risk factors appeared to differ between patients who developed a subsequent infection and those who did not...
Interstitial infusion of carmustine in the rat brain stem with systemic administration of O6-benzylguanineMark M Souweidane
Department of Neurological Surgery, The Weill Medical College of Cornell University, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Neurooncol 67:319-26. 2004....
Orbital recurrence of retinoblastoma following enucleationJ W Kim
Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
Br J Ophthalmol 93:463-7. 2009..To determine the incidence, clinical presentation and histopathological profile of patients developing orbital recurrence following enucleation for retinoblastoma...
Characteristics of oral mucosal events related to bevacizumab treatmentIgor T Gavrilovic
Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York 10022, USA
Oncologist 17:274-8. 2012..We aimed at providing a detailed clinical description of signs and symptoms limited to the tongue mucosa in patients treated with bevacizumab...
Third (fourth and fifth) nonocular tumors in survivors of retinoblastomaD H Abramson
Department of Ophthalmology, New York-Presbyterian Hospital, New York Weill Cornell Medical Center, New York, New York, USA
Ophthalmology 108:1868-76. 2001..The locations and expected ages at which additional tumors develop are consistent with the patterns we have seen in second tumors...
Engraftment and growth of patient-derived retinoblastoma tumour in severe combined immunodeficiency miceY Yan
Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Eur J Cancer 36:221-8. 2000..c. inoculation and suggest the possibility of using the SCID mouse model to study the intrinsic biological behaviour of human retinoblastoma and to develop novel therapeutic strategies in the treatment of this disease...
Outcome of children less than three years old at diagnosis with non-metastatic medulloblastoma treated with chemotherapy on the "Head Start" I and II protocolsGirish Dhall
Childrens Hospital Los Angeles, Los Angeles, California, USA
Pediatr Blood Cancer 50:1169-75. 2008..To determine the survival of infants and young children with non-metastatic medulloblastoma using intensive myeloablative chemotherapy and autologous hematopoietic progenitor cell rescue (AuHCR)...
Intensive cisplatin and cyclophosphamide-based chemotherapy without radiotherapy for intracranial germinomas: failure of a primary chemotherapy approachStewart J Kellie
Oncology Unit, The Children s Hospital at Westmead, Sydney, NSW, Australia
Pediatr Blood Cancer 43:126-33. 2004..The primary objective of this study was to determine whether intensive cisplatin and cyclophosphamide-based combination chemotherapy, without radiotherapy, was effective in patients with CNS germinomas...
Primary chemotherapy for intracranial nongerminomatous germ cell tumors: results of the second international CNS germ cell study group protocolStewart J Kellie
Oncology Unit, The Children s Hospital at Westmead, Locked Bag 4001, Westmead, NSW 2145, Australia
J Clin Oncol 22:846-53. 2004..The primary objective of this study was to determine whether intensive cisplatin and cyclophosphamide-based combination chemotherapy was effective in patients with intracranial NGGCT...
The adverse events of chemotherapy for retinoblastoma: what are they? Do we know?Allison E Rizzuti
Arch Ophthalmol 126:862-5. 2008
Analysis of outcome for patients with mass lesions of the central nervous system due to Langerhans cell histiocytosis treated with 2-chlorodeoxyadenosineGirish Dhall
Children s Hospital Los Angeles, Los Angeles, California, USA
Pediatr Blood Cancer 50:72-9. 2008..To assess the activity and tolerability of 2-chlorodeoxyadenosine (2-CDA) in treating mass lesions of the central nervous system (CNS) due to Langerhans cell histiocytosis (LCH)...
A proposal for an international retinoblastoma staging systemGuillermo Chantada
Department of Hematology Oncology, Hospital JP Garrahan, Buenos Aires, Argentina
Pediatr Blood Cancer 47:801-5. 2006..Comparisons among studies that consider disease extension, risk factors for extra-ocular relapse, and response to therapy require a universally accepted staging system for extra-ocular disease...
Treatment-related myelodysplastic syndrome after chemotherapy for childhood low-grade astrocytomaMatthias A Karajannis
J Pediatr Hematol Oncol 28:700. 2006
Secondary acute myelogenous leukemia in patients with retinoblastoma: is chemotherapy a factor?Dan S Gombos
Section of Ophthalmology, Department of Head and Neck Surgery, MD Anderson Cancer Center, Houston, Texas 77030, USA
Ophthalmology 114:1378-83. 2007..To describe a series of patients with secondary acute myelogenous leukemia (sAML) and retinoblastoma (RB)...
