Research Topics
| R J DowneySummaryAffiliation: Memorial Sloan-Kettering Cancer Center Country: USA Publications
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Detail Information
Publications
Anatomy of the normal diaphragmRobert Downey
Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, C 871, New York, NY 10065, USA
Thorac Surg Clin 21:273-9, ix. 2011..The function of the diaphragm is to expand the chest cavity during inspiration and to promote occlusion of the gastroesophageal junction. This article provides an overview of the normal anatomy of the diaphragm...
Extent of chest wall invasion and survival in patients with lung cancerR J Downey
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 68:188-93. 1999....- Surgery in the management of small cell lung cancerRobert J Downey
Division of Thoracic Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
J Natl Compr Canc Netw 2:159-62. 2004..However, a small number of patients present with resectable disease, and this review summarizes the available literature addressing the possible role for surgery in the treatment of these patients... - Fluorine-18 fluorodeoxyglucose positron emission tomographic maximal standardized uptake value predicts survival independent of clinical but not pathologic TNM staging of resected non-small cell lung cancerRobert J Downey
Thoracic Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Thorac Cardiovasc Surg 133:1419-27. 2007..The relative prognostic benefit of maximal standardized uptake value with respect to other clinical/pathologic variables has not been defined... - Surgery for colorectal and sarcomatous pulmonary metastases: history, current management, and future directionsRobert J Downey
Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
Thorac Surg Clin 16:133-7, v-vi. 2006.... - Invited commentaryRobert J Downey
Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
Ann Thorac Surg 80:1488. 2005 - Preoperative F-18 fluorodeoxyglucose-positron emission tomography maximal standardized uptake value predicts survival after lung cancer resectionRobert J Downey
Thoracic Surgery Service, Division of Nuclear Medicine, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
J Clin Oncol 22:3255-60. 2004.... - Whole body 18FDG-PET and the response of esophageal cancer to induction therapy: results of a prospective trialRobert J Downey
Thoracic Service and Gastric and Mixed Tumor Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Clin Oncol 21:428-32. 2003.... - A phase II trial of chemotherapy and surgery for non-small cell lung cancer patients with a synchronous solitary metastasisRobert J Downey
Thoracic Services, Memorial Sloan Kettering Cancer Center, Division of Thoracic Surgery, 1275 York Avenue, New York, NY 10021, USA
Lung Cancer 38:193-7. 2002..The feasibility and potential benefit of combining surgery and chemotherapy in this setting are unclear. Therefore, we performed a prospective trial to test this therapeutic approach... - Chest wall resection for locally recurrent breast cancer: is it worthwhile?R J Downey
Divisions of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Thorac Cardiovasc Surg 119:420-8. 2000..Reports to date have focused on technical feasibility, not long-term outcome... - Factors determining outcome after surgical resection of T3 and T4 lung cancers of the superior sulcusV W Rusch
Thoracic Surgery, Orthopedic Surgery, and Neurosurgery Services, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
J Thorac Cardiovasc Surg 119:1147-53. 2000..To establish a historical benchmark against which new therapies can be assessed, we reviewed our 24-year experience with patients undergoing thoracotomy for lung cancers of the superior sulcus... - Morbidity and mortality after neoadjuvant therapy for lung cancer: the risks of right pneumonectomyJ Martin
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 72:1149-54. 2001..However, right pneumonectomy is associated with a significantly increased risk and should be performed only in selected patients... - Effects of diltiazem prophylaxis on the incidence and clinical outcome of atrial arrhythmias after thoracic surgeryD Amar
Departments of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Thorac Cardiovasc Surg 120:790-8. 2000..We sought to determine whether early prophylaxis with an L -type calcium channel blocker reduces the incidence and morbidity associated with atrial fibrillation/flutter and supraventricular tachyarrhythmia after major thoracic operations... - The influence of hospital volume on survival after resection for lung cancerP B Bach
Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
N Engl J Med 345:181-8. 2001.... - A phase II trial of surgical resection and adjuvant high-dose hemithoracic radiation for malignant pleural mesotheliomaV W Rusch
Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Thorac Cardiovasc Surg 122:788-95. 2001..We performed a phase II trial of high-dose hemithoracic radiation after complete resection to determine feasibility and to estimate rates of local recurrence and survival... - Tension pneumocephalus resulting from iatrogenic subarachnoid-pleural fistulae: report of three casesM H Bilsky
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 71:455-7. 2001..Symptomatic pneumocephalus may result from a cerebrospinal fluid leak communicating with extradural air. However, it is a rare event after thoracic surgical procedures, and its management and physiology are not widely recognized... - The management of non-small-cell lung cancer with oligometastasesR J Downey
Division of Thoracic Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA
Chest Surg Clin N Am 11:121-32, ix. 2001.... - Feasibility of multimodality therapy including extended resections in stage IVA thymomaJames Huang
Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
J Thorac Cardiovasc Surg 134:1477-83; discussion 1483-4. 2007..We reviewed our experience with multimodality treatment for Masaoka stage IVA thymomas for feasibility and outcomes... - The utility of positron emission tomography in staging of potentially operable carcinoma of the thoracic esophagus: results of the American College of Surgeons Oncology Group Z0060 trialBryan F Meyers
Department of Surgery, Washington University School of Medicine, St Louis, MO
J Thorac Cardiovasc Surg 133:738-45. 2007.... - Radiofrequency ablation for pulmonary metastases: a therapy in evolutionMichael I Ebright
J Surg Oncol 96:365-6. 2007 - Protection of the mediastinum and chest wall with an artificial pneumothorax during lung ablationsStephen B Solomon
Section of Interventional Radiology and Image Guided Therapies, Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, H 210, New York, NY 10021, USA
J Vasc Interv Radiol 19:610-5. 2008..Pleural adhesions related to previous interventions may interfere with creation of a pneumothorax. Use of this technique could extend the utility of ablative therapies for lesions adjacent to the mediastinum and chest wall... - PET-guided induction chemotherapyRobert J Downey
Lancet Oncol 8:754-5. 2007 - Perioperative chemotherapy in patients undergoing pulmonary resection for metastatic soft-tissue sarcoma of the extremity : a retrospective analysisRobert J Canter
Division of Surgical Oncology, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Cancer 110:2050-60. 2007..To the authors' knowledge, few studies to date have examined the effect of chemotherapy in patients undergoing pulmonary resection for metastatic STS of the extremity... - Use of video-assisted thoracic surgery for lobectomy in the elderly results in fewer complicationsStephen M Cattaneo
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 85:231-5; discussion 235-6. 2008.... - Incidence and risk factors for lung injury after lung cancer resectionNaveed Alam
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 84:1085-91; discussion 1091. 2007..Our objective was to identify the incidence and risk factors for the development of postoperative lung injury... - An initial experience with FDG-PET in the imaging of residual disease after induction therapy for lung cancerTim Akhurst
Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 73:259-64; discussion 264-6. 2002..Aside from one 9-patient study, there are no data comparing FDG-PET imaging with surgical staging of NSCLC after induction therapy... - Non-small cell lung cancer with a solitary hematogenous metastasisRobert J Downey
Division of Thoracic Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Thorac Surg Clin 14:265-9, vii-viii. 2004..Future trials could be designed to include newer, less toxic chemotherapeutic regimens... - Long-term results of combined-modality therapy in resectable non-small-cell lung cancerJocelyne Martin
Thoracic Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
J Clin Oncol 20:1989-95. 2002..Survival is significantly influenced by patient age, complete resection, pathologic stage, and pneumonectomy. These results can help guide standard clinical practice and emphasize the need for novel induction regimens... - Resection of pulmonary metastases from colorectal cancerNabil P Rizk
Division of Thoracic Surgery, Memorial Sloan-Kettering Hospital, 1275 York Avenue, New York, NY 10021, USA
Semin Thorac Cardiovasc Surg 14:29-34. 2002..Data accumulated over the last 40 years support a survival benefit from resection of these lesions and have given a better understanding of the indications that should be adhered to in performing metastasectomy for colorectal cancer... - Clinical pattern and pathologic stage but not histologic features predict outcome for bronchioloalveolar carcinomaMichael I Ebright
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 74:1640-6; discussion 1646-7. 2002..The favorable survival of stage III/IV BAC indicates that the current staging system does not fully describe this disease in patients undergoing resection because of its distinct tumor behavior... - Management of major hemorrhage during mediastinoscopyBernard J Park
Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Room C 867, New York, NY 10021, USA
J Thorac Cardiovasc Surg 126:726-31. 2003..The management of major hemorrhage complicating mediastinoscopy is not well described. We reviewed our experience to determine the frequency, optimal management strategy, and outcome of these injuries... - Results of the American College of Surgeons Oncology Group Z0050 trial: the utility of positron emission tomography in staging potentially operable non-small cell lung cancerCarolyn E Reed
Hollings Cancer Center, Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston 29425, USA
J Thorac Cardiovasc Surg 126:1943-51. 2003.... - Surgical management of thoracic malignancies invading the heart or great vesselsBernard J Park
Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 78:1024-30. 2004..We reviewed our experience of 10 patients treated surgically, either primarily or as a component of multimodality therapy, to assess feasibility and results... - Advanced imaging including PET/CT for cardiothoracic surgeryLuc Bidaut
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Semin Thorac Cardiovasc Surg 16:272-82. 2004..This review will provide an overview of recent advances in imaging that are likely to influence the direction of cardiothoracic surgery in the near future... - Primary epithelial lung malignancies in the pediatric populationDave R Lal
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
Pediatr Blood Cancer 45:683-6. 2005..Patients with carcinoid tumors seem to have the best prognosis, followed by adenocarcinoma. The highly aggressive basaloid carcinoma has the worst... - Preoperative 18[F]-fluorodeoxyglucose positron emission tomography standardized uptake values predict survival after esophageal adenocarcinoma resectionNabil Rizk
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 81:1076-81. 2006.... - Results of chest wall resection and reconstruction with and without rigid prosthesisMichael J Weyant
Department of Surgery, Thoracic Service, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Thorac Surg 81:279-85. 2006..Pneumonectomy plus chest wall resection should be performed only in highly selected patients... - Small cell lung cancerGregory P Kalemkerian
J Natl Compr Canc Netw 6:294-314. 2008 - Small cell lung cancer clinical practice guidelines in oncologyBruce E Johnson
J Natl Compr Canc Netw 4:602-22. 2006