Research Topics
| Michael D'AngelicaSummaryAffiliation: Memorial Sloan-Kettering Cancer Center Country: USA Publications
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Detail Information
Publications
Lack of evidence for increased operative morbidity after hepatectomy with perioperative use of bevacizumab: a matched case-control studyMichael D'Angelica
Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
Ann Surg Oncol 14:759-65. 2007..Perioperative bev is now commonly used in patients undergoing hepatic resection. Little is known, however, about the safety of perioperative bev use in the setting of hepatic resection...
Actual 10-year survival after resection of colorectal liver metastases defines cureJames S Tomlinson
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Clin Oncol 25:4575-80. 2007..There is now sufficient follow-up on a significant number of patients to address the curative intent of resecting CLM...
Randomized clinical trials in advanced and metastatic colorectal carcinomaMichael I Dangelica
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Surg Oncol Clin N Am 11:173-91, ix. 2002..The advent of irinotecan has given us hope for a second line chemotherapeutic agent and a possible new combination for first line chemotherapy...
Analysis of the extent of resection for adenocarcinoma of the gallbladderMichael D'Angelica
Hepatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Ann Surg Oncol 16:806-16. 2009..Major hepatic resections, including major hepatectomy and CBD excision, are appropriate when necessary to clear disease but are not mandatory in all cases...
Patterns of initial recurrence in completely resected gastric adenocarcinomaMichael D'Angelica
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Ann Surg 240:808-16. 2004..To review recurrence patterns in completely resected gastric adenocarcinoma...
Effect on outcome of recurrence patterns after hepatectomy for colorectal metastasesMichael D'Angelica
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Ann Surg Oncol 18:1096-103. 2011..Despite improvements in surgery and chemotherapy, most patients develop recurrence after hepatectomy for metastatic colorectal cancer. Data are lacking on the effect of these patterns on outcome...
Accurate staging for gallbladder cancer: implications for surgical therapy and pathological assessmentHiromichi Ito
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Ann Surg 254:320-5. 2011..This study evaluates the significance of tumor involvement of the liver in early T-stage tumors and lymph node (LN) metastases on outcome after R0 resection of gallbladder cancer (GBCA)...
Selective use of diagnostic laparoscopy prior to planned hepatectomy for patients with hepatocellular carcinomaJurgen Weitz
Hepatobiliary Service and Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Surgery 135:273-81. 2004..Laparoscopy may reduce the rate of unnecessary laparotomy in these patients. However, there are no criteria for selective use of laparoscopy...
Interaction of splenectomy and perioperative blood transfusions on prognosis of patients with proximal gastric and gastroesophageal junction cancerJurgen Weitz
Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
J Clin Oncol 21:4597-603. 2003....
CT-guided radiofrequency ablation as a salvage treatment of colorectal cancer hepatic metastases developing after hepatectomyConstantinos T Sofocleous
Department of Interventional Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA
J Vasc Interv Radiol 22:755-61. 2011..To evaluate the clinical outcomes of percutaneous radiofrequency (RF) ablation of colorectal cancer liver metastases (CLMs) that recur after hepatectomy...
Synchronous hepatic metastases from colon cancer: changing treatment strategies and results of surgical interventionBridget N Fahy
Department of Surgery, The Methodist Hospital, Houston, TX 77030, USA
Ann Surg Oncol 16:361-70. 2009..A multidisciplinary treatment approach which combines both medical and surgical modalities may be associated with improved survival...
Effect of postoperative morbidity on long-term survival after hepatic resection for metastatic colorectal cancerHiromichi Ito
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Ann Surg 247:994-1002. 2008..The objective of this study was to evaluate the impact of postoperative morbidity on the long-term outcome after liver resection for MCRC...
Differential cell cycle-regulatory protein expression in biliary tract adenocarcinoma: correlation with anatomic site, pathologic variables, and clinical outcomeWilliam R Jarnagin
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Clin Oncol 24:1152-60. 2006..This clinicopathologic study characterizes differences in cell cycle-regulatory protein expression across the spectrum of BTA...
Clinical significance of intraoperative bile duct margin assessment for hilar cholangiocarcinomaItaru Endo
Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
Ann Surg Oncol 15:2104-12. 2008..Frozen section analysis of bile duct margins is often used to guide the extent of surgical resection for hilar cholangiocarcinoma (HCCA), but the usefulness of this practice is unknown...
Resection of adrenocortical carcinoma liver metastasis: is it justified?Sebastien Gaujoux
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Ann Surg Oncol 19:2643-51. 2012..Adrenocortical carcinoma (ACC) liver metastases (LM) represent a therapeutic challenge, and it is unclear whether resection is justified. This study assesses long-term outcome and prognostic factors after liver resection for metastatic ACC...
Impact of obesity and body fat distribution on survival after pancreaticoduodenectomy for pancreatic adenocarcinomaSebastien Gaujoux
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Ann Surg Oncol 19:2908-16. 2012..We sought to assess the influence of obesity and body fat distribution on pathologic characteristics and survival after pancreaticoduodenectomy for pancreatic adenocarcinoma...
The outcome of resected cystic pancreatic endocrine neoplasms: a case-matched analysisSebastien Gaujoux
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Surgery 151:518-25. 2012..Cystic pancreatic endocrine neoplasms (CPENs) are uncommon tumors with uncertain disease biology and ill-defined diagnostic features...
Intrahepatic cholangiocarcinoma: rising frequency, improved survival, and determinants of outcome after resectionItaru Endo
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Surg 248:84-96. 2008..This study analyzes changes in IHC frequency, demographics, and treatment outcome in a consecutive and single institutional cohort...
Increased use of parenchymal-sparing surgery for bilateral liver metastases from colorectal cancer is associated with improved mortality without change in oncologic outcome: trends in treatment over time in 440 patientsJason S Gold
Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Ann Surg 247:109-17. 2008..We aimed to assess the evolution of the technical approach over time and correlations with morbidity, mortality, and oncologic outcome...
Conversion to resectability using hepatic artery infusion plus systemic chemotherapy for the treatment of unresectable liver metastases from colorectal carcinomaNancy E Kemeny
Memorial Sloan Kettering Cancer Center, Weill Medical College of Cornell University, 1275 York Ave, New York, NY 10065, USA
J Clin Oncol 27:3465-71. 2009..Future randomized trials should compare HAI plus systemic chemotherapy with systemic therapy alone to assess the additional value of HAI therapy in converting patients with hepatic metastases to resectability...
Patterns of recurrence after ablation of colorectal cancer liver metastasesT Peter Kingham
Division of Hepatopancreatobiliary Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Ann Surg Oncol 19:834-41. 2012..To determine the local recurrence rate and factors associated with recurrence after intraoperative ablation of colorectal cancer liver metastases...
Kinetics of liver volume changes in the first year after portal vein embolizationDanton Corrêa
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Arch Surg 145:351-4; discussion 354-5. 2010..To determine the time course of liver hypertrophy after portal vein embolization (PVE)...
Simple measurement of intra-abdominal fat for abdominal surgery outcome predictionKatherine Morris
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Arch Surg 145:1069-73. 2010..To assess the effect of increasing body mass index, intra-abdominal fat, and outer abdominal fat on outcome in patients undergoing major hepatectomy...
Response to neoadjuvant chemotherapy does not predict overall survival for patients with synchronous colorectal hepatic metastasesDavid J Gallagher
Department of Medicine, Gastrointestinal Oncology Service, Division of Solid Tumor Oncology, Memorial Sloan Kettering Cancer Center and Joan and Sanford Weill Medical College of Cornell University, New York, NY, USA
Ann Surg Oncol 16:1844-51. 2009..We investigated the relation between response to neoadjuvant chemotherapy and overall survival (OS) in patients with colorectal liver metastases (CLM)...
Perihepatic lymph node micrometastases impact outcome after partial hepatectomy for colorectal metastasesJoseph J Bennett
Division of Hepatobiliary Surgery, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
Ann Surg Oncol 15:1130-6. 2008..This study uses standard pathologic analysis and immunohistochemistry (IHC) to determine the impact of occult metastatic disease to perihepatic LN in patients with colorectal cancer undergoing hepatectomy...
Use of intraoperative ablation as an adjunct to surgical resection in the treatment of recurrent colorectal liver metastasesAnand Govindarajan
Department of Surgery, Memorial Sloan Kettering Cancer Center, 444 E 68th Street, Room C887, New York, NY 10065, USA
J Gastrointest Surg 15:1168-72. 2011..To evaluate the role of intraoperative ablation as an adjunct to resection in patients with recurrent colorectal liver metastases (rCLM)...
Management of primary liver sarcomasJuürgen Weitz
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Cancer 109:1391-6. 2007..Primary hepatic sarcoma is a rare entity. The objectives of the study were to define treatment and long-term outcome and to identify prognostic factors...
Partial hepatectomy for metastases from noncolorectal, nonneuroendocrine carcinomaJurgen Weitz
Hepatobiliary Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Ann Surg 241:269-76. 2005..To define perioperative and long-term outcome and prognostic factors in patients undergoing hepatectomy for liver metastases arising from noncolorectal and nonneuroendocrine (NCNN) carcinoma...
Is detection of asymptomatic recurrence after curative resection associated with improved survival in patients with gastric cancer?Joseph J Bennett
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Am Coll Surg 201:503-10. 2005..In the context of a followup program after curative gastrectomy, recurrence and survival were investigated for patients presenting with either symptomatic or asymptomatic recurrence...
Synchronous resection of primary and liver metastases for neuroendocrine tumorsSebastien Gaujoux
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Ann Surg Oncol 19:4270-7. 2012..Surgical approach is an accepted approach for metastatic neuroendocrine tumors (NET), but the safety and effectiveness of synchronous liver metastases resection with primary and/or locally recurrent NET is unclear...
Incidence and management of pancreatic leaks after splenectomy with distal pancreatectomy performed during primary cytoreductive surgery for advanced ovarian, peritoneal and fallopian tube cancerSiobhan M Kehoe
Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, MRI 1026, New York, NY 10021, USA
Gynecol Oncol 112:496-500. 2009..To determine the incidence, management, and outcome of patients diagnosed with a pancreatic leak after a distal pancreatectomy during primary surgical cytoreduction for ovarian, peritoneal, or tubal cancer...
18F-fluorodeoxyglucose positron emission tomography influences management decisions in patients with biliary cancerCarlos U Corvera
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Am Coll Surg 206:57-65. 2008..The role of PET in detecting disease recurrence after resection was also examined...
Polypoid lesions of the gallbladder: diagnosis and followupHiromichi Ito
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Am Coll Surg 208:570-5. 2009..The aims of this study were to assess the natural history and the histologic characteristics of US-detected PLG...
Folate receptor-α expression in resectable hepatic colorectal cancer metastases: patterns and significanceMichael D'Angelica
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Mod Pathol 24:1221-8. 2011..The prognostic value of FRα expression and the utility of FRα-targeted therapies in stage-IV colorectal cancer patients deserve further exploration...
Profile of plasma angiogenic factors before and after hepatectomy for colorectal cancer liver metastasesSam S Yoon
Department of Surgery, Division of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, Yawkey 7B 7926, 55 Fruit Street, Boston, Massachusetts 02114, USA
Ann Surg Oncol 13:353-62. 2006..Circulating angiogenic factors in patients with colorectal cancer liver metastases may promote tumor growth and contribute to liver regeneration after partial hepatectomy...
T cell infiltrate predicts long-term survival following resection of colorectal cancer liver metastasesSteven C Katz
Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Ann Surg Oncol 16:2524-30. 2009..This study examines the correlation between TIL numbers and survival following hepatic resection...
Predicting the risk of perioperative transfusion for patients undergoing elective hepatectomyCamelia S Sima
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Ann Surg 250:914-21. 2009..To develop 2 instruments that predict the probability of perioperative red blood cell transfusion in patients undergoing elective liver resection for primary and secondary tumors...
A comparison of outcomes from treating hepatocellular carcinoma by hepatic artery embolization in patients younger or older than 70 yearsRaymond H Thornton
Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Cancer 115:5000-6. 2009..The objective of this study was to compare the morbidity, mortality, and survival of patients aged <70 years and aged > or =70 years who underwent hepatic arterial embolization (HAE) for the treatment of hepatocellular carcinoma (HCC)...
Patterns of initial disease recurrence after resection of gallbladder carcinoma and hilar cholangiocarcinoma: implications for adjuvant therapeutic strategiesWilliam R Jarnagin
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Cancer 98:1689-700. 2003....
Papillary phenotype confers improved survival after resection of hilar cholangiocarcinomaWilliam R Jarnagin
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Ann Surg 241:703-12; discussion 712-4. 2005..The current study compares outcome after resection of papillary hilar cholangiocarcinoma to that of the more common nodular-sclerosing subtype...
Phase I trial of systemic oxaliplatin combination chemotherapy with hepatic arterial infusion in patients with unresectable liver metastases from colorectal cancerNancy Kemeny
Gastrointestinal Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Clin Oncol 23:4888-96. 2005..To determine the maximum-tolerated dose (MTD) of concurrent systemic oxaliplatin (Oxal) combinations plus hepatic arterial infusion (HAI) in patients with unresectable hepatic metastases from colorectal cancer...
Genome wide analysis and clinical correlation of chromosomal and transcriptional mutations in cancers of the biliary tractGeorge Miller
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Exp Clin Cancer Res 28:62. 2009..The pathogenesis of biliary cancers is ill-defined. This study investigates changes in gene expression and copy number in biliary cancers and correlates these changes with anatomical site of origin, histopathology and outcome...
Role of intra-arterial hepatic chemotherapy in the treatment of colorectal cancer metastasesT Peter Kingham
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
J Surg Oncol 102:988-95. 2010..The role of hepatic arterial infusional therapy in treating hepatic colorectal metastases includes treating patients with both resectable and unresectable metastases in the adjuvant, neoadjuvant, or palliative settings...
Surgical treatment of hepatocellular carcinoma: expert consensus statementWilliam Jarnagin
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
HPB (Oxford) 12:302-10. 2010..Whether ablation of small tumors provides long term disease control that is comparable to resection remains unclear...
Combined portal vein embolization and neoadjuvant chemotherapy as a treatment strategy for resectable hepatic colorectal metastasesAnne M Covey
Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Ann Surg 247:451-5. 2008....
A selective approach to the resection of cystic lesions of the pancreas: results from 539 consecutive patientsPeter J Allen
Memorial Sloan Kettering Cancer Center, USA
Ann Surg 244:572-82. 2006..To define a group of patients with pancreatic cysts who do not require resection...
Laparoscopic adrenalectomy for isolated adrenal metastasisVivian E Strong
Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Ann Surg Oncol 14:3392-400. 2007....
Current utility of staging laparoscopy for pancreatic and peripancreatic neoplasmsRebekah White
Department of Surgical Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Am Coll Surg 206:445-50. 2008..The routine use of staging laparoscopy in patients with radiographically resectable pancreatic and peripancreatic neoplasms remains controversial...
Comparative genomic analysis of primary versus metastatic colorectal carcinomasEfsevia Vakiani
Memorial Sloan Kettering Cancer Center, New York, NY, USA
J Clin Oncol 30:2956-62. 2012..To compare the mutational and copy number profiles of primary and metastatic colorectal carcinomas (CRCs) using both unpaired and paired samples derived from primary and metastatic disease sites...
Resection of perihilar biliary schwannomaLucian Panait
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Surg Oncol 20:e157-9. 2011..Patients generally lack symptoms and seek medical attention when tumor growth causes obstructive jaundice. Preoperative diagnosis is difficult and resection is the treatment of choice...
Treatment of liver colorectal metastases: role of laparoscopy, radiofrequency ablation, and microwave coagulationFlavio G Rocha
Hepatopancreatobiliary Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
J Surg Oncol 102:968-74. 2010..This review will focus on the application and outcome of these techniques in patients with colorectal liver metastases...
Recurrence patterns of intraductal papillary mucinous neoplasms of the pancreas on enhanced computed tomographyJonathan Landa
Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
J Comput Assist Tomogr 33:838-43. 2009..To characterize imaging features and findings in recurrent intraductal papillary mucinous neoplasms (IPMN); thereby reconciling the "field defect" theory with the appearance of recurrences distant from the resection margin...
The international position on laparoscopic liver surgery: The Louisville Statement, 2008Joseph F Buell
Department of Surgery, Director of Transplantation, Jewish Hospital Transplant Center, 200 Abraham Flexner Way, Louisville, KY 40202, USA
Ann Surg 250:825-30. 2009..To summarize the current world position on laparoscopic liver surgery...
Randomized clinical trials in gastric cancerSharon M Weber
Section of Surgical Oncology, University of Wisconsin Hospital, Madison, USA
Surg Oncol Clin N Am 11:111-31, ix. 2002..In comparison, there were only six surgical trials evaluating the extent of either primary resection or lymphadenectomy...
Epidermal growth factor receptor expression and gene amplification in colorectal carcinoma: an immunohistochemical and chromogenic in situ hybridization studyJinru Shia
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Mod Pathol 18:1350-6. 2005..Additional studies are needed to determine whether epidermal growth factor receptor gene amplification bears any informative value in predicting response to cetuximab-based therapy...
Antibody-based therapies for colorectal cancerKi Young Chung
Gastrointestinal Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Oncologist 10:701-9. 2005..South San Francisco, CA, http://www.gene.com) and cetuximab (Erbitux; ImClone Systems, Inc., New York, http://www.imclone.com), in colorectal cancer...
Constitutive activation of STAT5A promotes human hematopoietic stem cell self-renewal and erythroid differentiationJan Jacob Schuringa
Laboratory of Developmental Hematopoiesis, Cell Biology Program, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
J Exp Med 200:623-35. 2004..Our data indicate that a persistent activation of STAT5A in human hematopoietic stem and progenitor cells results in their enhanced self-renewal and diverts differentiation to the erythroid lineage...
Constitutive activation of Flt3 and STAT5A enhances self-renewal and alters differentiation of hematopoietic stem cellsMalcolm A S Moore
Moore Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Exp Hematol 35:105-16. 2007..To model human leukemogenesis by transduction of human hematopoietic stem cells (HSC) with genes associated with leukemia and expressed in leukemic stem cells...
Cetuximab therapy and symptomatic hypomagnesemiaDeborah Schrag
Division of Gastrointestinal Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Box 221, New York, NY 10011, USA
J Natl Cancer Inst 97:1221-4. 2005..Because symptoms may be rapidly ameliorated with supplementation, we suggest that, when fatigue or hypocalcemia is encountered during cetuximab therapy, serum magnesium level be measured and repleted as necessary...
Adjuvant therapy of colon cancer: current status and future directionsKi Young Chung
Gastrointestinal Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021 and Weill Medical College of Cornell University, Ithaca, USA
Cancer J 13:192-7. 2007....
Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistryKi Young Chung
Gastrointestinal Oncology Service, Memorial Sloan Kettering Cancer Center, H 816, New York, NY 10021, USA
J Clin Oncol 23:1803-10. 2005....
Enforced expression of an Flt3 internal tandem duplication in human CD34+ cells confers properties of self-renewal and enhanced erythropoiesisKi Young Chung
Laboratory of Developmental Hematopoiesis, Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Blood 105:77-84. 2005..Flt3-ITD+ acute myeloid leukemia (AML) blasts from patients invariably generated early AG1295-sensitive CAs in MS-5 cocultures, further validating the phenotype observed in transduced CD34+ cells...
Liver cell adenoma: a multicenter analysis of risk factors for rupture and malignancyJEREMIAH L DENEVE
Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA
Ann Surg Oncol 16:640-8. 2009..Liver cell adenoma (LCA) is a benign hepatic tumor with poorly characterized risk for spontaneous rupture and malignant transformation...
CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumorsSergey V Shmelkov
Howard Hughes Medical Institute, Ansary Center for Stem Cell Therapeutics, and Department of Genetic Medicine, Weill Medical College of Cornell University, New York, New York, USA
J Clin Invest 118:2111-20. 2008....
Defining palliative surgery in patients receiving noncurative resections for gastric cancerThomas J Miner
Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
J Am Coll Surg 198:1013-21. 2004..Studies designed to measure palliative interventions would benefit from precise designations of palliative intent in patients receiving noncurative operations...
Clinical outcomes with laparoscopic stage M1, unresected gastric adenocarcinomaAbeezar I Sarela
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Ann Surg 243:189-95. 2006..Intervention-related mortality was minimal. The burden of metastatic disease and functional performance status were important prognostic factors...
Regional and systemic chemotherapy for primary hepatobiliary cancers and for colorectal cancer metastatic to the liverKi Young Chung
Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
Semin Radiat Oncol 15:284-98. 2005..Therefore, the regional approach for hepatobiliary tumors deserves further investigation as well as randomized trials for adequate comparison to new systemic chemotherapies...
Laparoscopic and hand-assisted laparoscopic splenectomy for recurrent and persistent ovarian cancerDennis S Chi
Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, MRI 1026, New York, NY 10021, USA
Gynecol Oncol 101:224-7. 2006..The purpose of this study was to report the outcomes of a series of patients who underwent splenectomy for persistent or recurrent ovarian cancer via laparoscopy or hand-assisted laparoscopy...
Biologic predictors of survival in node-negative gastric cancerDavid A Kooby
Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Ann Surg 237:828-35; discussion 835-7. 2003..CONCLUSIONS: Serosal invasion and presence of VI are strong predictors of poor survival in this disease. NI correlates with T stage and tumor size and may serve as a marker of advanced disease...
Accurate lymph node staging is of greater prognostic importance than subclassification of the T2 category for gastric adenocarcinomaAbeezar I Sarela
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
Ann Surg Oncol 10:783-91. 2003..44%). pN2 or pN3 were mainly limited to SS tumors and these patients had poor survival (26% and 0%). CONCLUSION: For pT2 gastric adenocarcinoma, the depth of mural invasion was not an independently significant prognostic factor...
Selection of patients with gastric adenocarcinoma for laparoscopic stagingAbeezar I Sarela
Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
Am J Surg 191:134-8. 2006..CONCLUSIONS: With spiral CT staging, laparoscopy may be avoided if the primary tumor is not at the GEJ or whole stomach and there is no lymphadenopathy...
Adenocarcinoma of the duodenum: importance of accurate lymph node staging and similarity in outcome to gastric cancerAbeezar I Sarela
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Ann Surg Oncol 11:380-6. 2004..With accurate nodal staging, pN0 was associated with excellent prognosis. With pN+, prognosis was similar to that for gastric antral adenocarcinoma...
The diminishing role of surgery in the treatment of gastric lymphomaSam S Yoon
Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA
Ann Surg 240:28-37. 2004..CONCLUSION: The treatment of gastric lymphoma continues to evolve, and surgical resection is now uncommonly a part of the initial management strategy...
Postoperative nomogram for disease-specific survival after an R0 resection for gastric carcinomaMichael W Kattan
Department of Urology, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, C1275 New York, NY 10021, USA
J Clin Oncol 21:3647-50. 2003..This tool should be useful for patient counseling, follow-up scheduling, and clinical trial eligibility determination...
Port site metastasis after diagnostic laparoscopy for upper gastrointestinal tract malignancies: an uncommon entityMargo Shoup
Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Ann Surg Oncol 9:632-6. 2002..Therefore, the risk of port site recurrence cannot be used as an argument against laparoscopy in upper GI malignancy...
Surgical approaches and outcomes in the treatment of gastric cancerHong Jin Kim
Department of Surgery, University of North Carolina, Chapel Hill, NC, USA
Semin Radiat Oncol 12:162-9. 2002..Patient selection remains critical, limiting the role of surgery in advanced disease and reserving aggressive surgical resection for patients with high curative potential...
Gastrectomy for gastric cancer: defining critical elements of patient selection and outcome assessmentThomas J Miner
Department of Surgery, Brown Medical School, 593 Eddy Street, APC 439, Providence, RI 02903, USA
Surg Oncol Clin N Am 13:455-66, viii. 2004..Studies designed to measure palliative interventions would benefit from precise designations of palliative intent inpatients receiving non-curative operations...
