Francesca Cole

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. pmc Preaching about the converted: how meiotic gene conversion influences genomic diversity
    Francesca Cole
    Developmental Biology Program, Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York, USA
    Ann N Y Acad Sci 1267:95-102. 2012
  2. pmc Evolutionary conservation of meiotic DSB proteins: more than just Spo11
    Francesca Cole
    Developmental Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Genes Dev 24:1201-7. 2010
  3. pmc Isolation of meiotic recombinants from mouse sperm
    Francesca Cole
    Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Methods Mol Biol 745:251-82. 2011
  4. pmc Homeostatic control of recombination is implemented progressively in mouse meiosis
    Francesca Cole
    Developmental Biology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA
    Nat Cell Biol 14:424-30. 2012
  5. pmc ATM controls meiotic double-strand-break formation
    Julian Lange
    Molecular Biology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA
    Nature 479:237-40. 2011
  6. pmc Comprehensive, fine-scale dissection of homologous recombination outcomes at a hot spot in mouse meiosis
    Francesca Cole
    Developmental Biology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Mol Cell 39:700-10. 2010

Research Grants

  1. Apoptosis in recombination-deficient meiocytes
    Francesca Cole; Fiscal Year: 2007

Collaborators

Detail Information

Publications6

  1. pmc Preaching about the converted: how meiotic gene conversion influences genomic diversity
    Francesca Cole
    Developmental Biology Program, Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York, USA
    Ann N Y Acad Sci 1267:95-102. 2012
    ..We discuss the potential impact of mammalian NCO characteristics on evolution and genomic diversity...
  2. pmc Evolutionary conservation of meiotic DSB proteins: more than just Spo11
    Francesca Cole
    Developmental Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Genes Dev 24:1201-7. 2010
    ..1266-1280) used a phylogenomic approach to identify two of these proteins across multiple clades, and confirmed that one of these, MEI4, is a functional ortholog in mouse...
  3. pmc Isolation of meiotic recombinants from mouse sperm
    Francesca Cole
    Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Methods Mol Biol 745:251-82. 2011
    ..Amplification of recombinant products directly from sperm DNA is a powerful approach to determine recombination frequencies and map recombination breakpoints, providing insight into homologous recombination mechanisms...
  4. pmc Homeostatic control of recombination is implemented progressively in mouse meiosis
    Francesca Cole
    Developmental Biology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA
    Nat Cell Biol 14:424-30. 2012
    ..Meiotic recombination exemplifies how order can be progressively implemented in a self-organizing system despite natural cell-to-cell disparities in the underlying biochemical processes...
  5. pmc ATM controls meiotic double-strand-break formation
    Julian Lange
    Molecular Biology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA
    Nature 479:237-40. 2011
    ..Our findings explain previously puzzling phenotypes of Atm-null mice and provide a molecular basis for the gonadal dysgenesis observed in ataxia telangiectasia, the human syndrome caused by ATM deficiency...
  6. pmc Comprehensive, fine-scale dissection of homologous recombination outcomes at a hot spot in mouse meiosis
    Francesca Cole
    Developmental Biology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Mol Cell 39:700-10. 2010
    ..Transmission distortion was observed in one hybrid, with NCOs providing a significant contribution. Thus, NCO recombination events play a substantial role in mammalian meiosis and genome evolution...

Research Grants2

  1. Apoptosis in recombination-deficient meiocytes
    Francesca Cole; Fiscal Year: 2007
    ....