Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA


  1. Zhang N, Yantiss R, Nam H, Chin Y, Zhou X, Scherl E, et al. ID1 is a functional marker for intestinal stem and progenitor cells required for normal response to injury. Stem Cell Reports. 2014;3:716-24 pubmed publisher
    ..These experiments identify ID1 as a marker for intestinal stem/progenitor cells and demonstrate a role for ID1 in maintaining the potential for repair in response to colonic injury. ..
  2. Cook P, Thomas R, Kingsley P, Shimizu F, Montrose D, Marnett L, et al. Cox-2-derived PGE2 induces Id1-dependent radiation resistance and self-renewal in experimental glioblastoma. Neuro Oncol. 2016;18:1379-89 pubmed publisher
    ..Collectively, these findings identify Id1 as a key mediator of PGE2-dependent modulation of radiation response and lend insight into the mechanisms underlying radiation resistance in GBM patients. ..
  3. request reprint
    Benezra R, Rafii S, Lyden D. The Id proteins and angiogenesis. Oncogene. 2001;20:8334-41 pubmed
    ..This section of the review issue will focus on the key observations which have led to these conclusions, speculations about potential mechanisms and the outlook for potential therapeutic interventions. ..
  4. Thomas R, Marks D, Chin Y, Benezra R. Whole chromosome loss and associated breakage-fusion-bridge cycles transform mouse tetraploid cells. EMBO J. 2018;37:201-218 pubmed publisher