Research Topics
| Juliet N BarkerSummaryAffiliation: Memorial Sloan-Kettering Cancer Center Country: USA Publications
| Collaborators
|
Detail Information
Publications
How I treat: the selection and acquisition of unrelated cord blood graftsJuliet N Barker
Allogeneic Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
Blood 117:2332-9. 2011..We also describe how we plan for unit shipment and the role of backup grafts. This review aims to provide a framework for CB unit selection and help transplantation centers perform efficient CB searches...- Successful treatment of EBV-associated posttransplantation lymphoma after cord blood transplantation using third-party EBV-specific cytotoxic T lymphocytesJuliet N Barker
Department of Medicine, Allogeneic Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Blood 116:5045-9. 2010..Such therapy may also be applicable to the treatment of other infections and residual or recurrent malignancy after CBT... 
Combined effect of total nucleated cell dose and HLA match on transplantation outcome in 1061 cord blood recipients with hematologic malignanciesJuliet N Barker
Memorial Sloan Kettering Cancer Center, New York, NY, USA
Blood 115:1843-9. 2010..These findings support new unit selection criteria that take into account both TNC dose and HLA-match and have important implications for the size of the global CB inventory needed to find an optimum CB graft...- A "no-wash" albumin-dextran dilution strategy for cord blood unit thaw: high rate of engraftment and a low incidence of serious infusion reactionsJuliet N Barker
Department of Medicine, Allogeneic Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Biol Blood Marrow Transplant 15:1596-602. 2009.... - Availability of cord blood extends allogeneic hematopoietic stem cell transplant access to racial and ethnic minoritiesJuliet N Barker
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Biol Blood Marrow Transplant 16:1541-8. 2010..Minority patients in need of allografts, but without suitable matched sibling donors, should be referred for combined URD and CB searches to optimize transplant access... - Pre-engraftment syndrome after double-unit cord blood transplantation: a distinct syndrome not associated with acute graft-versus-host diseaseKevin J Patel
Allogeneic Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
Biol Blood Marrow Transplant 16:435-40. 2010..PES is common after CBT, precedes neutrophil recovery, is distinct from and does not predict for aGVHD, and responds promptly to short-course corticosteroid therapy... - Cord blood units with low CD34+ cell viability have a low probability of engraftment after double unit transplantationAndromachi Scaradavou
Department of Pediatrics, Allogeneic Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
Biol Blood Marrow Transplant 16:500-8. 2010..02). Our data suggests one mechanism by which double unit CBT can improve engraftment is by increasing the probability of transplanting at least one unit with adequate viability and the potential to engraft... - Serious infection risk and immune recovery after double-unit cord blood transplantation without antithymocyte globulinCraig Sauter
Department of Medicine, Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Biol Blood Marrow Transplant 17:1460-71. 2011.... - Influence of infused cell dose and HLA match on engraftment after double-unit cord blood allograftsSharon Avery
Department of Medicine, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Blood 117:3277-85; quiz 3478. 2011..0001). Our findings have important implications for unit selection and provide further insight into double-unit biology... - Reduced late mortality risk contributes to similar survival after double-unit cord blood transplantation compared with related and unrelated donor hematopoietic stem cell transplantationDoris M Ponce
Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Biol Blood Marrow Transplant 17:1316-26. 2011..482). These data provide strong support for the further investigation of double-unit CB grafts as an alternative hematopoietic stem cell source... - Allogeneic hematopoietic stem cell transplantation in adult acute lymphocytic leukemia: impact of donor source on survivalPriya Kumar
Blood and Marrow Transplant Program, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA
Biol Blood Marrow Transplant 14:1394-400. 2008..4, 95% CI, 0.2-0.6, P < .01). When compared with URD:M, OS with UCB was better (RR 0.3, 95% CI, 0.1-0.7, P = .01), supporting the use of UCB as an alternative stem cell source for adults with ALL... 
Reduced intensity compared with high dose conditioning for allotransplantation in acute myeloid leukemia and myelodysplastic syndrome: a comparative clinical analysisCatherine M Flynn
Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
Am J Hematol 82:867-72. 2007..Advances in GVHD management and new approaches for relapsed or refractory disease are necessary to improve these outcomes...- Long-term survival in patients with peripheral T-cell non-Hodgkin lymphomas after allogeneic hematopoietic stem cell transplantJenna D Goldberg
Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Leuk Lymphoma 53:1124-9. 2012..These data demonstrate that allogeneic transplant is a viable option for the treatment of T-NHL and merits prospective evaluation... - Adoptive immunotherapy with unselected or EBV-specific T cells for biopsy-proven EBV+ lymphomas after allogeneic hematopoietic cell transplantationEkaterina Doubrovina
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Blood 119:2644-56. 2012.... - The use of back-up units to enhance the safety of unrelated donor cord blood transplantationDoris M Ponce
Adult Bone Marrow Transplantation, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Biol Blood Marrow Transplant 18:648-51. 2012..We demonstrate that back-up units are emergently required in a significant minority of patients, supporting the incorporation of at least 1 back-up unit in cord blood (CB) selection algorithms to enhance CBT safety... - Optimizing unrelated donor cord blood transplantationJuliet N Barker
Memorial Sloan Kettering Cancer Center, New York, New York, USA
Biol Blood Marrow Transplant 15:154-61. 2009..This review will address efforts to optimize CBT from 3 different perspectives: that of the transplant center, the CBT registry, and the CB bank... - Searching for unrelated donor hematopoietic stem cells: availability and speed of umbilical cord blood versus bone marrowJuliet N Barker
Department of Medicine, University of Minnesota School of Medicine, Minneapolis, USA
Biol Blood Marrow Transplant 8:257-60. 2002..These unique features of UCB transplantation must be considered in comparisons of the outcomes of UCB versus BM transplant recipients and in the design of prospective trials comparing URD sources... - Double unit grafts successfully extend the application of umbilical cord blood transplantation in adults with acute leukemiaAndromachi Scaradavou
New York Blood Center, New York, NY, USA
Blood 121:752-8. 2013..KEY POINTS: Efficacy of transplanting adequately dosed 1- or 2-cord blood units... - An in vivo model of double-unit cord blood transplantation that correlates with clinical engraftmentLamis K Eldjerou
Allogeneic Bone Marrow Transplantation, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Blood 116:3999-4006. 2010..Thus, unit dominance is an in vivo phenomenon probably associated with a graft-versus-graft immune interaction mediated by CD34(-) cells... - Unrelated donor umbilical cord blood transplantation for the treatment of hematologic malignanciesCraig Sauter
Adult Allogeneic Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Curr Opin Hematol 15:568-75. 2008.... - T cell-depleted stem cell transplantation for adults with high-risk acute lymphoblastic leukemia: long-term survival for patients in first complete remission with a decreased risk of graft-versus-host diseaseJenna D Goldberg
Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Biol Blood Marrow Transplant 19:208-13. 2013..15 (95% CI, 0.04-0.26), and that of extensive chronic GVHD at 2 and 5 years was 0.05 (95% CI, 0-11.6). We demonstrate OS and DFS rates that compare favorably to unmodified allo-HSCT with lower rates of GVHD... - Marked increased risk of Epstein-Barr virus-related complications with the addition of antithymocyte globulin to a nonmyeloablative conditioning prior to unrelated umbilical cord blood transplantationClaudio G Brunstein
Blood and Marrow Transplant Program, Department of Medicine, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455, USA
Blood 108:2874-80. 2006..Use of ATG in recipients of an NMA preparative regimen warrants close monitoring for evidence of EBV reactivation and potentially preemptive therapy with rituximab... - Randomized comparison of granulocyte colony-stimulating factor versus granulocyte-macrophage colony-stimulating factor plus intensive chemotherapy for peripheral blood stem cell mobilization and autologous transplantation in multiple myelomaMukta Arora
Department of Medicine, University of Minnesota, Minneapolis 55455, USA
Biol Blood Marrow Transplant 10:395-404. 2004..Two cycles of priming chemotherapy plus autologous transplantation yields survival rates similar to those in published reports, including those using tandem transplantation... - Umbilical-cord blood transplantation for the treatment of cancerJuliet N Barker
Department of Medicine, Blood and Marrow Transplant Program of the University of Minnesota School of Medicine, 420 Delaware Street, S E, Minneapolis, Minnesota 55455, USA
Nat Rev Cancer 3:526-32. 2003..These studies have identified several advantages to umbilical-cord cell transplantation, including a lower incidence of GVHD. Umbilical-cord blood is therefore a promising alternative to bone-marrow-derived stem cells... - Adenovirus viremia and disease: comparison of T cell-depleted and conventional hematopoietic stem cell transplantation recipients from a single institutionYeon Joo Lee
Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Biol Blood Marrow Transplant 19:387-92. 2013..The benefit of preemptive therapy for an ADV viral load ≥10,000 copies/mL for preventing ADV disease in TCD HSCT recipients should be evaluated in prospective clinical trials... - Umbilical cord blood transplantation: current practice and future innovationsJuliet N Barker
Department of Medicine, Blood and Marrow Transplant Program of the University of Minnesota School of Medicine, University of Minnesota, MMC 480 UMHC, 420 Delaware Street, SE, Minneapolis, MN 55455, USA
Crit Rev Oncol Hematol 48:35-43. 2003..This review outlines the current status of UCBT with emphasis on current and future innovations... - Cord blood transplants: one, two or more units?Sharon Avery
Department of Medicine, Allogeneic Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Curr Opin Hematol 17:531-7. 2010..This review summarizes the current status of double-unit cord blood transplantation (CBT) to improve engraftment, reduce transplant-related mortality, and improve disease-free survival... - Umbilical cord blood transplantation: current state of the artJuliet N Barker
Department of Medicine, Blood and Marrow Transplant Program, University of Minnesota School of Medicine, Minneapolis, Minnesota 55455, USA
Curr Opin Oncol 14:160-4. 2002....