Research Topics
Species | Zhirong BaoSummaryAffiliation: Memorial Sloan-Kettering Cancer Center Country: USA Publications
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Detail Information
Publications
Control of cell cycle timing during C. elegans embryogenesisZhirong Bao
Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
Dev Biol 318:65-72. 2008..elegans embryogenesis as a model to dissect the interaction between differentiation and proliferation, and an effective approach combining genetic and statistical analysis at single-cell resolution...
Actomyosin-based self-organization of cell internalization during C. elegans gastrulationChristian Pohl
Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA
BMC Biol 10:94. 2012..Despite the conservation of gastrulation as a key event in Metazoan embryogenesis, the morphogenetic mechanisms of self-organization (how global order or coordination can arise from local interactions) are poorly understood...
Multidimensional regulation of gene expression in the C. elegans embryoJohn Isaac Murray
Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA
Genome Res 22:1282-94. 2012..The resulting data sets will be a useful resource for future research...
Automated analysis of embryonic gene expression with cellular resolution in C. elegansJohn Isaac Murray
Department of Genome Sciences, University of Washington School of Medicine, 1705 NE Pacific Street, Seattle, Washington 98195, USA
Nat Methods 5:703-9. 2008..Systematic application of this system could reveal the gene activity of each cell throughout development...
The lineaging of fluorescently-labeled Caenorhabditis elegans embryos with StarryNite and AceTreeJohn Isaac Murray
Department of Genome Sciences, University of Washington Box 357730, Seattle, Washington 98195, USA
Nat Protoc 1:1468-76. 2006..The protocol requires about 1 h of user time spread over 2 days to generate the raw lineage, and an additional 2 or 4 h to edit the lineage to the 194- or 350-cell stage, respectively...
Comparative analysis of embryonic cell lineage between Caenorhabditis briggsae and Caenorhabditis elegansZhongying Zhao
Department of Genome Sciences, Box 355065, University of Washington, 1705 NE Pacific St, Seattle, WA 98195 5065, USA
Dev Biol 314:93-9. 2008....
Specific roles for the GATA transcription factors end-1 and end-3 during C. elegans E-lineage developmentMax E Boeck
Department of Genome Sciences, University of Washington School of Medicine, 1705 NE Pacific Street, Seattle, WA 98195, USA
Dev Biol 358:345-55. 2011....
AceTree: a tool for visual analysis of Caenorhabditis elegans embryogenesisThomas J Boyle
Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA
BMC Bioinformatics 7:275. 2006....
Chiral forces organize left-right patterning in C. elegans by uncoupling midline and anteroposterior axisChristian Pohl
Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA
Dev Cell 19:402-12. 2010..Chiral morphogenesis is timed by the cytokinetic furrow of a neighbor of the sister pair, providing a developmental clock and an unexpected signaling interaction between the contractile ring and the adjacent cells...
Automated cell lineage tracing in Caenorhabditis elegansZhirong Bao
Department of Genome Sciences, University of Washington, WA 98195, USA
Proc Natl Acad Sci U S A 103:2707-12. 2006..We envision that this automation will make it practical to systematically decipher the developmental genes and pathways encoded in the genome of C. elegans...
A hybrid blob-slice model for accurate and efficient detection of fluorescence labeled nuclei in 3DAnthony Santella
Developmental Biology, Sloan Kettering Institute, 1275 York Avenue, New York, New York 10065, USA
BMC Bioinformatics 11:580. 2010..Variability in nuclear appearance and undersampled volumetric data make this a challenge...
The genome sequence of Caenorhabditis briggsae: a platform for comparative genomicsLincoln D Stein
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA
PLoS Biol 1:E45. 2003..elegans genome. Based on similarity to C. briggsae, we found strong evidence for 1,300 new C. elegans genes. In addition, comparisons of the two genomes will help to understand the evolutionary forces that mold nematode genomes...
Genomics in C. elegans: so many genes, such a little wormLadeana W Hillier
Genome Sequencing Center, Washington University School of Medicine, St. Louis, Missouri 63108, USA
Genome Res 15:1651-60. 2005..We now have a solid platform on which to build toward the lofty goal of a true molecular understanding of worm biology with all its implications including those for human health...
