Genomes and Genes
Affiliation: Memorial Sloan-Kettering Cancer Center
- Ars2 maintains neural stem-cell identity through direct transcriptional activation of Sox2Celia Andreu-Agullo
Department of Developmental Biology, Sloan Kettering Institute, 1275 York Avenue, Box 252, New York, New York 10065, USA
Nature 481:195-8. 2012..Our findings reveal Ars2 as a new transcription factor that controls the multipotent progenitor state of NSCs through direct activation of the pluripotency factor Sox2...
- Widespread and extensive lengthening of 3' UTRs in the mammalian brainPedro Miura
Department of Developmental Biology, Sloan Kettering Institute, New York, New York 10065, USA
Genome Res 23:812-25. 2013..Altogether, these new 3' UTR annotations greatly expand the scope of post-transcriptional regulatory networks in mammals, and have particular impact on the central nervous system...
- BEND6 is a nuclear antagonist of Notch signaling during self-renewal of neural stem cellsQi Dai
Department of Developmental Biology, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10065, USA
Development 140:1892-902. 2013..These data reveal a novel mammalian CSL co-repressor in the nervous system, and show that the Notch-inhibitory activity of certain BEN-solo proteins is conserved between flies and mammals...