D B Agus

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. ncbi Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transporters
    D B Agus
    Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Clin Invest 100:2842-8. 1997
  2. ncbi Positron emission tomography of a human prostate cancer xenograft: association of changes in deoxyglucose accumulation with other measures of outcome following androgen withdrawal
    D B Agus
    Department of Medicine and Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer Res 58:3009-14. 1998
  3. ncbi Stromal cell oxidation: a mechanism by which tumors obtain vitamin C
    D B Agus
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer Res 59:4555-8. 1999
  4. ncbi Response of prostate cancer to anti-Her-2/neu antibody in androgen-dependent and -independent human xenograft models
    D B Agus
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer Res 59:4761-4. 1999
  5. ncbi Prostate cancer cell cycle regulators: response to androgen withdrawal and development of androgen independence
    D B Agus
    Department of Medicine, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Natl Cancer Inst 91:1869-76. 1999
  6. ncbi Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide, an inhibitor of histone deacetylase
    L M Butler
    Cell Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
    Clin Cancer Res 7:962-70. 2001
  7. ncbi Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke
    J Huang
    Department of Neurological Surgery, College of Physicians and Surgeons, Columbia University, 710 West 168th Street, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 98:11720-4. 2001

Collaborators

Detail Information

Publications7

  1. ncbi Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transporters
    D B Agus
    Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Clin Invest 100:2842-8. 1997
    ..These results have implications for increasing antioxidant potential in the central nervous system...
  2. ncbi Positron emission tomography of a human prostate cancer xenograft: association of changes in deoxyglucose accumulation with other measures of outcome following androgen withdrawal
    D B Agus
    Department of Medicine and Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer Res 58:3009-14. 1998
    ..The results suggest that serial monitoring of DOG accumulation using PET scanning may be useful as an early indicator of treatment efficacy and other outcome measures in prostate cancer...
  3. ncbi Stromal cell oxidation: a mechanism by which tumors obtain vitamin C
    D B Agus
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer Res 59:4555-8. 1999
    ....
  4. ncbi Response of prostate cancer to anti-Her-2/neu antibody in androgen-dependent and -independent human xenograft models
    D B Agus
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer Res 59:4761-4. 1999
    ..These results suggest the utility of Herceptin in the treatment of human prostate cancer...
  5. ncbi Prostate cancer cell cycle regulators: response to androgen withdrawal and development of androgen independence
    D B Agus
    Department of Medicine, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Natl Cancer Inst 91:1869-76. 1999
    ..To understand the factors associated with regression of prostate cancers after androgen withdrawal, we studied cell cycle regulator changes in the CWR22 human prostate cancer xenograft model...
  6. ncbi Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide, an inhibitor of histone deacetylase
    L M Butler
    Cell Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
    Clin Cancer Res 7:962-70. 2001
    ..CONCLUSIONS: The findings suggest that pyroxamide may be a useful agent for the treatment of malignancy and that induction of p21/WAF1 in transformed cells by pyroxamide may contribute to the antitumor effects of this agent...
  7. ncbi Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke
    J Huang
    Department of Neurological Surgery, College of Physicians and Surgeons, Columbia University, 710 West 168th Street, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 98:11720-4. 2001
    ..As a naturally occurring interconvertible form of AA with BBB permeability, DHA represents a promising pharmacological therapy for stroke based on its effects in this model of cerebral ischemia...