David H Abramson

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. doi request reprint Superselective ophthalmic artery chemotherapy as primary treatment for retinoblastoma (chemosurgery)
    David H Abramson
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Ophthalmology 117:1623-9. 2010
  2. pmc Histopathologic findings of eyes enucleated after treatment with chemosurgery for retinoblastoma
    Carolyn P Graeber
    Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Open Ophthalmol J 5:1-5. 2011
  3. pmc Retinoblastoma presenting in a child with hypomelanosis of ito
    Tarek El-Sawy
    Department of Ophthalmology, Columbia University Medical Center, New York, NY, USA
    Open Ophthalmol J 5:55-8. 2011
  4. doi request reprint Retinoblastoma: saving life with vision
    David H Abramson
    Weill Cornell Medical College, Memorial Sloan Kettering Cancer Center, New York, New York 10021 email
    Annu Rev Med 65:171-84. 2014
  5. doi request reprint Ophthalmic artery chemosurgery for retinoblastoma prevents new intraocular tumors
    David H Abramson
    Department of Ophthalmology at Weill Cornell Medical School, New York, New York, USA
    Ophthalmology 120:560-5. 2013
  6. pmc Ophthalmic artery chemosurgery for less advanced intraocular retinoblastoma: five year review
    David H Abramson
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
    PLoS ONE 7:e34120. 2012
  7. doi request reprint Intra-arterial chemotherapy for retinoblastoma in eyes with vitreous and/or subretinal seeding: 2-year results
    David H Abramson
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Br J Ophthalmol 96:499-502. 2012
  8. ncbi request reprint Retinoblastoma in the 20th century: past success and future challenges the Weisenfeld lecture
    David H Abramson
    Ophthalmic Oncology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10023, USA
    Invest Ophthalmol Vis Sci 46:2683-91. 2005
  9. ncbi request reprint Tadalafil-induced subretinal and choroidal hemorrhage in a patient with an unsuspected uveal (choroidal and ciliary body) melanoma
    David H Abramson
    Arch Ophthalmol 124:1058-60. 2006
  10. ncbi request reprint Periocular mucosa-associated lymphoid/low grade lymphomas: treatment with antibiotics
    David H Abramson
    Ophthalmic Oncology Service, Department Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Am J Ophthalmol 140:729-30. 2005

Detail Information

Publications94

  1. doi request reprint Superselective ophthalmic artery chemotherapy as primary treatment for retinoblastoma (chemosurgery)
    David H Abramson
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Ophthalmology 117:1623-9. 2010
    ..To report on our 3-year experience with the use of superselective ophthalmic artery infusion of chemotherapy as initial, primary treatment for intraocular retinoblastoma...
  2. pmc Histopathologic findings of eyes enucleated after treatment with chemosurgery for retinoblastoma
    Carolyn P Graeber
    Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Open Ophthalmol J 5:1-5. 2011
    ..MATERIALS AND METHODOLOGY: Independent histopathologic review of the enucleated eyes was correlated with the clinical findings that prompted enucleation...
  3. pmc Retinoblastoma presenting in a child with hypomelanosis of ito
    Tarek El-Sawy
    Department of Ophthalmology, Columbia University Medical Center, New York, NY, USA
    Open Ophthalmol J 5:55-8. 2011
    ..To describe a case of a child with a known history of pigmentary mosaicism suggestive of Hypomelanosis of Ito presenting with unilateral leukocoria, who was ultimately diagnosed with retinoblastoma...
  4. doi request reprint Retinoblastoma: saving life with vision
    David H Abramson
    Weill Cornell Medical College, Memorial Sloan Kettering Cancer Center, New York, New York 10021 email
    Annu Rev Med 65:171-84. 2014
    ..The introduction of ophthalmic artery chemosurgery has been the most dramatic, non-radiation-based mode to maximally preserve vision. ..
  5. doi request reprint Ophthalmic artery chemosurgery for retinoblastoma prevents new intraocular tumors
    David H Abramson
    Department of Ophthalmology at Weill Cornell Medical School, New York, New York, USA
    Ophthalmology 120:560-5. 2013
    ..To determine the incidence and timing of new intraocular tumor foci in genetic retinoblastoma cases after treatment with ophthalmic artery chemosurgery (OAC)...
  6. pmc Ophthalmic artery chemosurgery for less advanced intraocular retinoblastoma: five year review
    David H Abramson
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
    PLoS ONE 7:e34120. 2012
    ....
  7. doi request reprint Intra-arterial chemotherapy for retinoblastoma in eyes with vitreous and/or subretinal seeding: 2-year results
    David H Abramson
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Br J Ophthalmol 96:499-502. 2012
    ..To review the effectiveness of intra-arterial chemotherapy for advanced intra-ocular retinoblastoma with vitreous and/or subretinal seeds in naive (untreated) and previously treated eyes...
  8. ncbi request reprint Retinoblastoma in the 20th century: past success and future challenges the Weisenfeld lecture
    David H Abramson
    Ophthalmic Oncology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10023, USA
    Invest Ophthalmol Vis Sci 46:2683-91. 2005
  9. ncbi request reprint Tadalafil-induced subretinal and choroidal hemorrhage in a patient with an unsuspected uveal (choroidal and ciliary body) melanoma
    David H Abramson
    Arch Ophthalmol 124:1058-60. 2006
  10. ncbi request reprint Periocular mucosa-associated lymphoid/low grade lymphomas: treatment with antibiotics
    David H Abramson
    Ophthalmic Oncology Service, Department Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Am J Ophthalmol 140:729-30. 2005
    ..To report on the treatment of primary mucosa-associated lymphoid tumors (MALT)/low grade lymphomas of the conjunctiva/orbit treated solely with systemic antibiotics...
  11. doi request reprint Trilateral retinoblastoma: potentially curable with intensive chemotherapy
    Ira J Dunkel
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Pediatr Blood Cancer 54:384-7. 2010
    ..We describe a series of 13 patients treated with intensive chemotherapy, defined as the intention to include high-dose chemotherapy with autologous hematopoietic stem cell rescue...
  12. ncbi request reprint Persistence of retinal function after selective ophthalmic artery chemotherapy infusion for retinoblastoma
    Scott E Brodie
    Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Doc Ophthalmol 119:13-22. 2009
    ..To assess potential retinal viability by electroretinography following selective ophthalmic artery chemotherapy infusion for retinoblastoma...
  13. ncbi request reprint Intra-arterial and oral digoxin therapy for retinoblastoma
    Mrinali Patel
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, USA
    Ophthalmic Genet 32:147-50. 2011
    ..Preclinical studies demonstrate that cardiac glycosides such as ouabain and digoxin have antitumor effects on retinoblastoma cells in vitro and in a xenograft murine model of retinoblastoma...
  14. ncbi request reprint A phase II trial of carboplatin for intraocular retinoblastoma
    Ira J Dunkel
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Pediatr Blood Cancer 49:643-8. 2007
    ....
  15. pmc Carboplatin +/- topotecan ophthalmic artery chemosurgery for intraocular retinoblastoma
    Jasmine H Francis
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    PLoS ONE 8:e72441. 2013
    ..We aimed to assess the efficacy and toxicity of carboplatin +/- topotecan delivered by ophthalmic artery chemosurgery whereby chemotherapy is infused into the eye via the ophthalmic artery...
  16. ncbi request reprint Outcome following initial external beam radiotherapy in patients with Reese-Ellsworth group Vb retinoblastoma
    David H Abramson
    Department of Ophthalmology, New York Presbyterian Hospital Weill Medical College of Cornell University, 70 E 66th Street, New York, NY 10021, USA
    Arch Ophthalmol 122:1316-23. 2004
    ..To describe patient and ocular outcomes following initial treatment with external beam radiotherapy (EBT) in eyes with Reese-Ellsworth group Vb retinoblastoma...
  17. doi request reprint Non-selectivity of ERG reductions in eyes treated for retinoblastoma
    Catherine Y Liu
    Ophthalmic Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Doc Ophthalmol 128:13-23. 2014
    ....
  18. doi request reprint Salvage/adjuvant brachytherapy after ophthalmic artery chemosurgery for intraocular retinoblastoma
    Jasmine H Francis
    Memorial Sloan Kettering Cancer Center, New York, New York Electronic address
    Int J Radiat Oncol Biol Phys 87:517-23. 2013
    ..To evaluate the efficacy and toxicity of brachytherapy after ophthalmic artery chemosurgery (OAC) for retinoblastoma...
  19. ncbi request reprint Long-term medical outcomes in survivors of extra-ocular retinoblastoma: the Memorial Sloan-Kettering Cancer Center (MSKCC) experience
    Danielle Novetsky Friedman
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Pediatr Blood Cancer 60:694-9. 2013
    ..Data on long-term outcomes of survivors of extra-ocular retinoblastoma are lacking. The authors sought to provide the first report characterizing long-term outcomes among survivors of extra-ocular retinoblastoma...
  20. doi request reprint Indocyanine green enhanced transpupillary thermotherapy in combination with ophthalmic artery chemosurgery for retinoblastoma
    Jasmine H Francis
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, 70 East 66th Street, New York, NY 10065, USA
    Br J Ophthalmol 97:164-8. 2013
    ..Review our experience in the use of indocyanine green (ICG) enhanced transpupillary thermotherapy (TTT) in combination with ophthalmic artery chemosurgery for retinoblastomas unresponsive to standard TTT...
  21. doi request reprint ERG monitoring of retinal function during systemic chemotherapy for retinoblastoma
    Scott E Brodie
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Br J Ophthalmol 96:877-80. 2012
    ..In this paper, we report ERG results for patients with retinoblastoma receiving initial treatment with systemic chemotherapy...
  22. doi request reprint Ophthalmic artery chemosurgery for the management of retinoblastoma in eyes with extensive (>50%) retinal detachment
    Sotiria Palioura
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Pediatr Blood Cancer 59:859-64. 2012
    ..e. ophthalmic artery chemosurgery, has been used for the treatment of advanced intraocular retinoblastoma. Herein, we evaluate the efficacy of ophthalmic artery chemosurgery for retinoblastoma associated with >50% retinal detachment...
  23. ncbi request reprint Three-drug intra-arterial chemotherapy using simultaneous carboplatin, topotecan and melphalan for intraocular retinoblastoma: preliminary results
    Brian P Marr
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Br J Ophthalmol 96:1300-3. 2012
    ..To report outcomes with selective intra-arterial chemotherapy (SIAC) using simultaneous carboplatin, topotecan, and melphalan for advanced intraocular retinoblastoma...
  24. doi request reprint Success of intra-arterial chemotherapy (chemosurgery) for retinoblastoma: effect of orbitovascular anatomy
    Brian P Marr
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Arch Ophthalmol 130:180-5. 2012
    ....
  25. doi request reprint A phase I/II study of direct intraarterial (ophthalmic artery) chemotherapy with melphalan for intraocular retinoblastoma initial results
    David H Abramson
    Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ophthalmology 115:1398-404, 1404.e1. 2008
    ....
  26. doi request reprint Persistence of retinal function after intravitreal melphalan injection for retinoblastoma
    Scott E Brodie
    Department of Ophthalmic Oncology, Memorial Sloan Kettering Cancer Center, Mount Sinai School of Medicine, New York, NY, USA
    Doc Ophthalmol 126:79-84. 2013
    ..We report clinical and electroretinography results after 6 months of one patient who has shown a favorable initial clinical response to intravitreal melphalan injections for treatment of refractory vitreous seeds...
  27. pmc Tumor-associated retinal astrocytes promote retinoblastoma cell proliferation through production of IGFBP-5
    Xiaoliang L Xu
    Dyson Vision Research Institute, Weill Medical College of Cornell University, New York, New York, USA
    Am J Pathol 177:424-35. 2010
    ..These observations suggest that a tissue-specific microenvironmental feature cooperates with oncogenic mutations in a cancer cell of origin to promote retinoblastoma tumorigenesis...
  28. doi request reprint High-dose chemotherapy with autologous hematopoietic stem cell rescue for stage 4B retinoblastoma
    Ira J Dunkel
    Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Pediatr Blood Cancer 55:149-52. 2010
    ..Here we describe a series of eight patients treated with intensive chemotherapy, defined as the intention to include high-dose chemotherapy with autologous hematopoietic stem cell rescue...
  29. doi request reprint Intra-arterial chemotherapy for the management of retinoblastoma: four-year experience
    Y Pierre Gobin
    Interventional Neuroradiology, Departments of Radiology and Neurosurgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10065, USA
    Arch Ophthalmol 129:732-7. 2011
    ..Retinoblastoma often presents with advanced intraocular disease and, despite conventional treatment with intravenous chemotherapy and external beam radiation therapy, may still require enucleation...
  30. doi request reprint Ocular manipulation reduces both ipsilateral and contralateral electroretinograms
    Jasmine H Francis
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Doc Ophthalmol 127:113-22. 2013
    ..To determine the electroretinogram (ERG) changes in eyes manipulated in the course of local ablative therapy (transpupil thermotherapy (TTT), cryotherapy or both) or scleral depression and in un-manipulated fellow, healthy eyes...
  31. pmc Combined, sequential intravenous and intra-arterial chemotherapy (bridge chemotherapy) for young infants with retinoblastoma
    Y Pierre Gobin
    Service of Interventional Neuroradiology, Department of Neurosurgery, Weill Cornell Medical College of New York Presbyterian Hospital, New York, New York, United States of America
    PLoS ONE 7:e44322. 2012
    ..a.) chemotherapy has more risks of procedural complications in neonates and young infants. For these reasons, we have developed a strategy of bridge intravenous single agent chemotherapy to postpone i.a. chemotherapy in these children..
  32. doi request reprint Periocular carboplatin for retinoblastoma: long-term report (12 years) on efficacy and toxicity
    Brian P Marr
    Department of Surgery, Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, 70 East 66th Street, New York, NY 10065, USA
    Br J Ophthalmol 96:881-3. 2012
    ..To report the experience of the authors with efficacy and toxicity of periocular chemotherapy over a 12-year period...
  33. pmc A synergetic screening approach with companion effector for combination therapy: application to retinoblastoma
    Jeni P Mahida
    HTS Core Facility, Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
    PLoS ONE 8:e59156. 2013
    ..Our results validate this alternative approach, and we expect that our companion effector strategy could significantly impact both drug discovery and the nutraceutical industry...
  34. doi request reprint Diagnosis of retinoblastoma: how good are referring physicians?
    Jesse L Maki
    Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Ophthalmic Genet 30:199-205. 2009
    ..To evaluate accuracy of the referring diagnoses of retinoblastoma to a tertiary cancer referral center...
  35. ncbi request reprint Cell cycle-specific and cell type-specific expression of Rb in the developing human retina
    Thomas C Lee
    Margaret M Dyson Vision Research Institute, Weill Medical College of Cornell University, New York, New York 10021, USA
    Invest Ophthalmol Vis Sci 47:5590-8. 2006
    ..To define the pattern of Rb expression relative to cell cycle position and cell type in the developing human retina...
  36. doi request reprint Intensive multimodality therapy for patients with stage 4a metastatic retinoblastoma
    Ira J Dunkel
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Pediatr Blood Cancer 55:55-9. 2010
    ....
  37. ncbi request reprint New retinoblastoma tumor formation in children initially treated with systemic carboplatin
    Thomas C Lee
    Department of Ophthalmology, New York Presbyterian Hospital Weill Medical College of Cornell University, 70 East 66th Street, New York, NY 10021, USA
    Ophthalmology 110:1989-94; discussion 1994-5. 2003
    ..To determine the frequency and timing of new intraocular tumor formation in children with hereditary retinoblastoma initially treated with systemic carboplatin...
  38. doi request reprint Characterization of computed tomography scan abnormalities in patients with biopsy-proven hepatic metastases from uveal melanoma
    Mrinali Patel
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 70 E 66th St, New York, NY 10065, USA
    Arch Ophthalmol 129:1576-82. 2011
    ..To describe the computed tomography (CT) features in patients with biopsy-proven hepatic metastases of uveal melanoma and correlate these findings with survival...
  39. doi request reprint Published international classification of retinoblastoma (ICRB) definitions contain inconsistencies--an analysis of impact
    Danielle E Novetsky
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ophthalmic Genet 30:40-4. 2009
    ..To determine the impact of subtle differences (most notably in their classification of group E eyes) in two published versions of the ICRB (Philadelphia and the Children's Hospital Los Angeles)...
  40. ncbi request reprint Current management strategies for intraocular retinoblastoma
    Jonathan W Kim
    Department of Ophthalmic Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Drugs 67:2173-85. 2007
    ..Therefore, modern centres treating retinoblastoma continue to manage patients with a variety of modalities, individualising the therapy according to the patient's presentation and clinical course...
  41. ncbi request reprint Update on retinoblastoma
    David H Abramson
    Ophthalmic Oncology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Retina 24:828-48. 2004
  42. pmc Whole-body magnetic resonance imaging (WB-MRI) as surveillance for subsequent malignancies in survivors of hereditary retinoblastoma: A pilot study
    Danielle Novetsky Friedman
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York
    Pediatr Blood Cancer 61:1440-4. 2014
    ..We hypothesized that annual surveillance using whole-body magnetic resonance imaging (WB-MRI) in asymptomatic survivors of hereditary RB would detect SMN of the bone and soft tissues at an early stage...
  43. ncbi request reprint Chorioretinal scar growth after 810-nanometer laser treatment for retinoblastoma
    Thomas C Lee
    Ophthalmic Oncology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Ophthalmology 111:992-6. 2004
    ..To determine the extent of expansion of laser scars after single treatment with transpupillary thermotherapy (TTT) for retinoblastoma...
  44. pmc Increased risk of secondary uterine leiomyosarcoma in hereditary retinoblastoma
    Jasmine H Francis
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Gynecol Oncol 124:254-9. 2012
    ..As our cohort is followed for a longer period, we discover new second malignancy risks for these patients...
  45. pmc Intraocular hemorrhage after intra-arterial chemotherapy for retinoblastoma in sickle cell trait
    David H Abramson
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, USA
    Open Ophthalmol J 6:1-3. 2012
    ..Clinicians should be on the lookout for the association of sickle-cell disease/trait and intraocular hemorrhages after intraarterial chemotherapy to fully understand its clinical significance...
  46. doi request reprint Distinction of conjunctival melanocytic nevi from melanomas by fluorescence in situ hybridization
    Klaus J Busam
    Department of Pathology, Ophthalmologic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Cutan Pathol 37:196-203. 2010
    ..The findings encourage further exploration of this technique as an ancillary method for the work-up of conjunctival melanocytic proliferations...
  47. ncbi request reprint Variates of survival in metastatic uveal melanoma
    Petra Rietschel
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Clin Oncol 23:8076-80. 2005
    ..We evaluated the survival of our patients with metastatic uveal melanoma, described factors that correlated with survival, and evaluated the influence of screening tests on time of detection and survival...
  48. ncbi request reprint Screening for retinoblastoma: presenting signs as prognosticators of patient and ocular survival
    David H Abramson
    Robert M Ellsworth Ophthalmic Oncology Center, Department of Ophthalmology, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, USA
    Pediatrics 112:1248-55. 2003
    ..To correlate 3 common presenting signs of retinoblastoma with patient and ocular survival and to assess the efficacy of current pediatric screening practices for retinoblastoma...
  49. pmc Revisiting old drugs as novel agents for retinoblastoma: in vitro and in vivo antitumor activity of cardenolides
    Christophe Antczak
    High Throughput Screening Core Facility, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Invest Ophthalmol Vis Sci 50:3065-73. 2009
    ..It allows local delivery of relatively high doses of chemotherapy agents while bypassing general blood circulation. For this reason, this study was undertaken to revisit some of the FDA-approved drugs for the treatment of retinoblastoma...
  50. doi request reprint Retinoblastoma has properties of a cone precursor tumor and depends upon cone-specific MDM2 signaling
    Xiaoliang L Xu
    Dyson Vision Research Institute, Weill Cornell Medical College, New York, NY 10021, USA
    Cell 137:1018-31. 2009
    ..These findings provide support for a cone precursor origin of retinoblastoma and suggest that human cone-specific signaling circuitry sensitizes to the oncogenic effects of RB1 mutations...
  51. pmc Electroretinogram monitoring of dose-dependent toxicity after ophthalmic artery chemosurgery in retinoblastoma eyes: six year review
    Jasmine H Francis
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
    PLoS ONE 9:e84247. 2014
    ..To report electroretinogram responses of retinoblastoma children under anesthesia before and after treatment with chemotherapeutic drugs (melphalan, topotecan, carboplatin) delivery by ophthalmic artery chemosurgery (OAC)...
  52. pmc Rb induces a proliferative arrest and curtails Brn-2 expression in retinoblastoma cells
    David Cobrinik
    Margaret M, Dyson Vision Research Institute, Weill Medical College of Cornell University, New York, NY 10021, USA
    Mol Cancer 5:72. 2006
    ..Retinoblastoma is caused by loss of the Rb protein in early retinal cells. Although numerous Rb functions have been identified, Rb effects that specifically relate to the suppression of retinoblastoma have not been defined...
  53. ncbi request reprint Impairments in antifolate transport are common in retinoblastoma tumor samples
    Richard G Gorlick
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Pediatr Blood Cancer 50:573-6. 2008
    ..Identification of effective chemotherapy agents for retinoblastoma that are not associated with an elevated risk of secondary malignancy would be beneficial...
  54. ncbi request reprint Visual fields in retinoblastoma survivors
    David H Abramson
    Ophthalmology Oncology Service, Departments of Surgery, Radiation Oncology, and Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY
    Arch Ophthalmol 122:1324-30. 2004
    ..To describe the visual field defects in retinoblastoma survivors and relate those defects to characteristics such as tumor size, tumor location, and treatment modality...
  55. doi request reprint Fibrin sealant for retinoblastoma: where are we?
    Nancy E Martin
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Ocul Pharmacol Ther 24:433-8. 2008
    ..This review integrates the recent ophthalmology and pharmaceutics literature on the potential role of fibrin sealants for periocular chemotherapy administration in the treatment of retinoblastoma...
  56. ncbi request reprint RETINAL TOXICITIES OF CANCER THERAPY DRUGS: Biologics, Small Molecule Inhibitors, and Chemotherapies
    Catherine Y Liu
    The Gavin Herbert Eye Institute, University of California, Irvine, California Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, New York Department of Ophthalmology, Mayo School of Graduate Medical Education, Mayo Clinic, Rochester, Minnesota Byers Eye Institute at Stanford, Stanford University School of Medicine, Palo Alto, California and Weill Cornell Medical College, New York, New York
    Retina 34:1261-80. 2014
    ..To review reported retinal side effects from current cancer therapy drugs...
  57. ncbi request reprint Treatment of choroidal melanoma using photodynamic therapy
    Irene A Barbazetto
    E S Harkness Eye Institute, New York Presbyterian Hospital, Columbia University, New York, New York 10032, USA
    Am J Ophthalmol 135:898-9. 2003
    ..To InternetAdvance publication at ajo.com Feb 26, 2002. investigate the effect of photodynamic therapy using verteporfin on choroidal melanoma...
  58. ncbi request reprint Brain necrosis after enucleation, external beam cobalt radiotherapy, and systemic chemotherapy for retinoblastoma
    Gilbert D A Padula
    Department of Ophthalmology, Weill Medical College of Cornell University, New York, NY 10021, USA
    Arch Ophthalmol 120:98-9. 2002
  59. pmc Sinonasal adenocarcinoma: a rare second malignancy in long term retinoblastoma survivors
    Pooja Bhagia
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Pediatr Blood Cancer 57:693-5. 2011
    ..Sinonasal adenocarcinoma should be considered as a second malignancy in retinoblastoma survivors who present with vague sinus symptoms...
  60. ncbi request reprint Lack of activity of oral etoposide for relapsed intraocular retinoblastoma
    Ira J Dunkel
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Ophthalmic Genet 25:25-9. 2004
    ..Because oral etoposide has been found to be highly effective in patients with relapsed medulloblastoma and neuroblastoma who had previously received intravenous etoposide, we investigated its use for intraocular retinoblastoma...
  61. ncbi request reprint Transpupillary thermotherapy as initial treatment for small intraocular retinoblastoma: technique and predictors of success
    David H Abramson
    Department of Ophthalmology, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, New York, USA
    Ophthalmology 111:984-91. 2004
    ..To determine which small retinoblastoma tumors can be treated with transpupillary thermotherapy (TTT) alone and to clarify the minimum amount of treatment required to prevent recurrence...
  62. ncbi request reprint Optic nerve tissue shrinkage during pathologic processing after enucleation for retinoblastoma
    David H Abramson
    Department of Ophthalmology, New York Presyterian Hospital Weill Medical College of Cornell University, New York, NY, USA
    Arch Ophthalmol 121:73-5. 2003
    ..To quantify and analyze the differences between the length of the optic nerve as measured by the ophthalmologist in the operating room after enucleation and the length as measured by the pathologist after fixation...
  63. doi request reprint Therapeutic implications of the emerging molecular biology of uveal melanoma
    Mrinali Patel
    Department of Medicine and Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Clin Cancer Res 17:2087-100. 2011
    ....
  64. doi request reprint Primary melanoma of the optic nerve in a patient with 16-year follow up
    Mrinali Patel
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, U S A
    Ophthal Plast Reconstr Surg 27:e69-71. 2011
    ..The authors present a case of primary melanoma of the optic nerve in a patient with no history of pigmentary disorder and 16 years of follow up...
  65. ncbi request reprint More aggressive bone marrow screening in retinoblastoma patients is not indicated: the memorial Sloan-Kettering cancer center experience
    Stergios Zacharoulis
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Pediatr Blood Cancer 46:56-61. 2006
    ....
  66. ncbi request reprint Osteogenic sarcoma in a survivor of metastatic germline retinoblastoma: the possible influence of human growth hormone
    David H Abramson
    New York Presbyterian Hospital, Weill Medical College, Cornell University, New York, USA
    J Pediatr Ophthalmol Strabismus 39:347-8. 2002
  67. ncbi request reprint Preimplantation genetic diagnosis for retinoblastoma: the first reported liveborn
    Kangpu Xu
    Institute for Reproductive Medicine, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, New York 10021, USA
    Am J Ophthalmol 137:18-23. 2004
    ....
  68. ncbi request reprint Small molecule inhibition of HDM2 leads to p53-mediated cell death in retinoblastoma cells
    Jasmine R Elison
    Department of Ophthalmology, Weill Medical College of Cornell University, New York Presbyterian Hospital, 520 E 70th Street, New York, NY 10021, USA
    Arch Ophthalmol 124:1269-75. 2006
    ..To determine the efficacy of inducing p53-mediated cell death in retinoblastoma cells by Nutlin 3A, a small molecule HDM2 inhibitor...
  69. ncbi request reprint Impact on survivors of retinoblastoma when informed of study results on risk of second cancers
    Charlene J Schulz
    Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Med Pediatr Oncol 41:36-43. 2003
    ..To assess the impact of providing research feedback to retinoblastoma survivors or their parents regarding the risk of second cancers...
  70. ncbi request reprint Delayed diagnosis of retinoblastoma: analysis of degree, cause, and potential consequences
    Linda J Butros
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Pediatrics 109:E45. 2002
    ..To assess the degree, cause, and consequence of delays from presenting signs to diagnosis of retinoblastoma...
  71. ncbi request reprint Fruit and vegetable intake during pregnancy and risk for development of sporadic retinoblastoma
    Manuela A Orjuela
    Department of Pediatrics, Mailman School of Public Health at Columbia University, Room B106, 60 Haven Avenue, New York, New York 10032, USA
    Cancer Epidemiol Biomarkers Prev 14:1433-40. 2005
    ..Fruits and vegetables are important sources of carotenoids and folate. We examined whether decreased gestational maternal intake of fruits and vegetables may contribute to development of sporadic retinoblastoma...
  72. pmc Spontaneously Resolving Periocular Erythema and Ciliary Madarosis Following Intra-arterial Chemotherapy for Retinoblastoma
    Brian Marr
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Middle East Afr J Ophthalmol 17:207-9. 2010
    ..To describe an unusual clinical finding seen in children undergoing intra-arterial chemotherapy for retinoblastoma...
  73. pmc Topical treatment options for conjunctival neoplasms
    Jonathan W Kim
    Ophthalmic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Clin Ophthalmol 2:503-15. 2008
    ....
  74. ncbi request reprint High-frequency ultrasonographic evaluation of conjunctival intraepithelial neoplasia and squamous cell carcinoma
    Paul T Finger
    Eye Cancer Center, The New York Eye and Ear Infirmary, 115 E 61st St, New York, NY 10021, USA
    Arch Ophthalmol 121:168-72. 2003
    ..To evaluate the high-frequency B-scan ultrasonographic characteristics of squamous conjunctival neoplasia (conjunctival intraepithelial neoplasia and squamous cell carcinoma)...
  75. ncbi request reprint Periocular chemotherapy for retinoblastoma: success with problems?
    David H Abramson
    Arch Ophthalmol 123:128-9; author reply 129. 2005
  76. ncbi request reprint Risk factors for extraocular relapse following enucleation after failure of chemoreduction in retinoblastoma
    Guillermo L Chantada
    Department of Hemato Oncology, Hospital JP Garrahan, Buenos Aires, Argentina, and Department of Pathology, University of Sao Paulo, Brazil
    Pediatr Blood Cancer 49:256-60. 2007
    ..To assess the outcome and determine risk factors for extraocular relapse in patients with retinoblastoma who had been enucleated after failure of chemoreduction...
  77. ncbi request reprint Rapid growth of retinoblastoma in a premature twin
    David H Abramson
    Arch Ophthalmol 120:1232-3. 2002
  78. ncbi request reprint Risk of new cancers after radiotherapy in long-term survivors of retinoblastoma: an extended follow-up
    Ruth A Kleinerman
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852 7362, USA
    J Clin Oncol 23:2272-9. 2005
    ..We have extended the follow-up of a large cohort of Rb patients for 7 more years to provide new information on the risk of additional cancers after radiotherapy in long-term survivors...
  79. ncbi request reprint (Neonatal) retinoblastoma in the first month of life
    David H Abramson
    Robert M Ellsworth Ophthalmic Oncology Center, New York Presbyterian Hospital Weill Cornell Medical College, NY, USA
    Arch Ophthalmol 120:738-42. 2002
    ..To identify patients with retinoblastoma whose conditions were diagnosed at the age of 1 month or younger and to describe their clinical features (including ocular and patient survival) and the development of second nonocular tumors...
  80. ncbi request reprint Topotecan vitreous levels after periocular or intravenous delivery in rabbits: an alternative for retinoblastoma chemotherapy
    Angel M Carcaboso
    Departments of Pharmacology, Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires, Buenos Aires, Argentina
    Invest Ophthalmol Vis Sci 48:3761-7. 2007
    ..To determine the extent and the mechanism by which topotecan, a candidate agent for the treatment of retinoblastoma, gains access to the vitreous when administered by periocular injection or intravenous infusion...
  81. ncbi request reprint The adverse events of chemotherapy for retinoblastoma: what are they? Do we know?
    Allison E Rizzuti
    Arch Ophthalmol 126:862-5. 2008
  82. ncbi request reprint Primary ophthalmic rhabdomyosarcoma
    David H Abramson
    Ophthalmology 110:877; author reply 877-8. 2003
  83. ncbi request reprint Risk of soft tissue sarcomas by individual subtype in survivors of hereditary retinoblastoma
    Ruth A Kleinerman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, EPS 7044, 6120 Executive Blvd, Rockville, MD 20852, USA
    J Natl Cancer Inst 99:24-31. 2007
    ..Survivors of hereditary retinoblastoma have an increased risk for second malignancies, especially soft tissue sarcomas. However, the risks of individual histologic subtypes of soft tissue sarcomas have not been evaluated...
  84. ncbi request reprint Secondary acute myelogenous leukemia in patients with retinoblastoma: is chemotherapy a factor?
    Dan S Gombos
    Section of Ophthalmology, Department of Head and Neck Surgery, MD Anderson Cancer Center, Houston, Texas 77030, USA
    Ophthalmology 114:1378-83. 2007
    ..To describe a series of patients with secondary acute myelogenous leukemia (sAML) and retinoblastoma (RB)...
  85. ncbi request reprint Bilateral retinoblastoma, microphthalmia, and colobomas in the 13q deletion syndrome
    Lisa S Schocket
    Scheie Eye Institute, University of Pennsylvania, Philadelphia 19104, USA
    Arch Ophthalmol 121:916-7. 2003
  86. pmc Cancer screening practices of adult survivors of retinoblastoma at risk of second cancers
    Victoria Sheen
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Cancer 113:434-41. 2008
    ..The aim of the current study was to investigate the pattern of cancer screening behavior in adult retinoblastoma survivors, who are at high risk of developing second cancers...
  87. ncbi request reprint Microsatellite instability and MLH1 promoter methylation in human retinoblastoma
    Kwong Wai Choy
    Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Kowloon
    Invest Ophthalmol Vis Sci 45:3404-9. 2004
    ..To investigate the link between microsatellite instability and epigenetic silencing of the MLH1 gene in the human retinoblastoma genome...
  88. ncbi request reprint Growing melanocytic tumor is not always cancer
    David H Abramson
    Arch Ophthalmol 123:1457-8. 2005
  89. ncbi request reprint Treatment of conjunctival squamous cell carcinoma with photodynamic therapy
    Irene A Barbazetto
    E S Harkness Eye Institute, New York Presbyterian Hospital, Columbia University, New York 10032, USA
    Am J Ophthalmol 138:183-9. 2004
    ..The aim of this study was to describe the clinical and angiographic response of squamous cell carcinoma (SCC) of the conjunctiva to treatment with photodynamic therapy (PDT)...
  90. ncbi request reprint Pediatric ophthalmic computed tomographic scanning and associated cancer risk
    David H Abramson
    Am J Ophthalmol 143:908-9; author reply 909. 2007
  91. ncbi request reprint An aggressive bone marrow evaluation including immunocytology with GD2 for advanced retinoblastoma
    Guillermo L Chantada
    Department of Hemato Oncology, Hospital JP Garrahan, Buenos Aires, Argentina
    J Pediatr Hematol Oncol 28:369-73. 2006
    ..GD2 was intensively expressed and it may also be used to monitor disease response and the presence of minimal residual disease...
  92. ncbi request reprint Metastatic ocular melanoma
    David H Abramson
    Arch Ophthalmol 122:658-9. 2004
  93. ncbi request reprint Tobacco use in adult long-term survivors of retinoblastoma
    Meredith C Foster
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, EPS 7044, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 15:1464-8. 2006
    ..Smoking did not account for the increased risk of lung cancer among hereditary Rb patients, and this may point to an enhanced sensitivity to the carcinogenic effects of tobacco. Adult survivors of Rb should be encouraged to stop smoking...
  94. pmc Clinical implications of promoter hypermethylation in RASSF1A and MGMT in retinoblastoma
    Kwong Wai Choy
    Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye Hospital, Kowloon, Hong Kong, China
    Neoplasia 7:200-6. 2005
    ..Epigenetic mechanism plays an important role in the progression of retinoblastoma...