Garry Steil

Summary

Affiliation: Medtronic Inc
Country: USA

Publications

  1. ncbi Determination of plasma glucose during rapid glucose excursions with a subcutaneous glucose sensor
    Garry M Steil
    Division of Research and Development, Medtronic MiniMed, Inc, Northridge, California, USA
    Diabetes Technol Ther 5:27-31. 2003
  2. ncbi Closed-loop insulin delivery - what lies between where we are and where we are going?
    Garry M Steil
    Medtronic MiniMed, Northridge, CA 91325, USA
    Expert Opin Drug Deliv 2:353-62. 2005
  3. doi Fully automated closed-loop insulin delivery versus semiautomated hybrid control in pediatric patients with type 1 diabetes using an artificial pancreas
    Stuart A Weinzimer
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
    Diabetes Care 31:934-9. 2008
  4. ncbi Interstitial fluid glucose dynamics during insulin-induced hypoglycaemia
    G M Steil
    Division of Research and Development, Medtronic MiniMed, 18000 Devonshire Street, Northridge, CA 91325, USA
    Diabetologia 48:1833-40. 2005
  5. ncbi Metabolic modelling and the closed-loop insulin delivery problem
    Garry Steil
    Medtronic MiniMed, Northridge, CA 91325, USA
    Diabetes Res Clin Pract 74:S183-6. 2006
  6. ncbi Feasibility of automating insulin delivery for the treatment of type 1 diabetes
    Garry M Steil
    Medtronic MiniMed, 18000 Devonshire St, Northridge, CA 91325, USA
    Diabetes 55:3344-50. 2006
  7. ncbi Modeling beta-cell insulin secretion--implications for closed-loop glucose homeostasis
    Garry M Steil
    Medtronic MiniMed, Inc, Northridge, California 91325, USA
    Diabetes Technol Ther 5:953-64. 2003
  8. ncbi Evaluation of insulin sensitivity and beta-cell function indexes obtained from minimal model analysis of a meal tolerance test
    Garry M Steil
    Medtronic MiniMed, 18000 Devonshire Street, Northridge, CA 91325, USA
    Diabetes 53:1201-7. 2004
  9. ncbi Modeling insulin action for development of a closed-loop artificial pancreas
    G M Steil
    Medtronic MiniMed, Northridge, California 91325, USA
    Diabetes Technol Ther 7:94-108. 2005
  10. ncbi Closed-loop insulin delivery-the path to physiological glucose control
    G M Steil
    Medtronic MiniMed Department, Sensor R and D, 18000 Devonshire St, Northridge, CA 91325 1219, USA
    Adv Drug Deliv Rev 56:125-44. 2004

Detail Information

Publications14

  1. ncbi Determination of plasma glucose during rapid glucose excursions with a subcutaneous glucose sensor
    Garry M Steil
    Division of Research and Development, Medtronic MiniMed, Inc, Northridge, California, USA
    Diabetes Technol Ther 5:27-31. 2003
    ..The rapid response should be sufficient to allow a fully automated closed-loop insulin delivery system to be developed based on the subcutaneous sensing site...
  2. ncbi Closed-loop insulin delivery - what lies between where we are and where we are going?
    Garry M Steil
    Medtronic MiniMed, Northridge, CA 91325, USA
    Expert Opin Drug Deliv 2:353-62. 2005
    ..Existing strategies for open-loop pump therapy are presented with the objective of defining a path to advance from the existing physician/patient determined insulin therapy to a completely automated system...
  3. doi Fully automated closed-loop insulin delivery versus semiautomated hybrid control in pediatric patients with type 1 diabetes using an artificial pancreas
    Stuart A Weinzimer
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
    Diabetes Care 31:934-9. 2008
    ..However, delays in insulin absorption associated with the subcutaneous route of delivery inevitably lead to large postprandial glucose excursions...
  4. ncbi Interstitial fluid glucose dynamics during insulin-induced hypoglycaemia
    G M Steil
    Division of Research and Development, Medtronic MiniMed, 18000 Devonshire Street, Northridge, CA 91325, USA
    Diabetologia 48:1833-40. 2005
    ..The aim of the present study was to define these relationships during hypoglycaemia in a well-equilibrated system with no smoothing...
  5. ncbi Metabolic modelling and the closed-loop insulin delivery problem
    Garry Steil
    Medtronic MiniMed, Northridge, CA 91325, USA
    Diabetes Res Clin Pract 74:S183-6. 2006
    ..This approach is contrasted with traditional control systems engineering...
  6. ncbi Feasibility of automating insulin delivery for the treatment of type 1 diabetes
    Garry M Steil
    Medtronic MiniMed, 18000 Devonshire St, Northridge, CA 91325, USA
    Diabetes 55:3344-50. 2006
    ..There were no episodes of severe hypoglycemia. The data provide proof of concept that glycemic control can be achieved by a completely automated external closed-loop insulin delivery system...
  7. ncbi Modeling beta-cell insulin secretion--implications for closed-loop glucose homeostasis
    Garry M Steil
    Medtronic MiniMed, Inc, Northridge, California 91325, USA
    Diabetes Technol Ther 5:953-64. 2003
    ..However, the PID model could maintain fasting euglycemia and was more stable under closed-loop conditions, and thus is more suited for such conditions...
  8. ncbi Evaluation of insulin sensitivity and beta-cell function indexes obtained from minimal model analysis of a meal tolerance test
    Garry M Steil
    Medtronic MiniMed, 18000 Devonshire Street, Northridge, CA 91325, USA
    Diabetes 53:1201-7. 2004
    ..In conclusion, insulin sensitivity and beta-cell indexes derived from a meal are not analogous to those from the clamp or IVGTT. Further work is needed before these indexes can be routinely used in clinical and epidemiological studies...
  9. ncbi Modeling insulin action for development of a closed-loop artificial pancreas
    G M Steil
    Medtronic MiniMed, Northridge, California 91325, USA
    Diabetes Technol Ther 7:94-108. 2005
    ..While no consensus model is proposed, relevant issues needing to be addressed are highlighted...
  10. ncbi Closed-loop insulin delivery-the path to physiological glucose control
    G M Steil
    Medtronic MiniMed Department, Sensor R and D, 18000 Devonshire St, Northridge, CA 91325 1219, USA
    Adv Drug Deliv Rev 56:125-44. 2004
    ..Experimental closed-loop data employing intravenous and subcutaneous glucose sensors and implanted and external insulin pumps (Medtronic MiniMed, Northridge CA) are presented...
  11. ncbi Can interstitial glucose assessment replace blood glucose measurements?
    K Rebrin
    MiniMed, Inc, Sylmar, California 91342, USA
    Diabetes Technol Ther 2:461-72. 2000
    ..We conclude that the differences between plasma and ISF glucose will not be a significant obstacle in advancing the use of ISF as an alternative to blood glucose measurements...
  12. ncbi Evaluation of the effect of gain on the meal response of an automated closed-loop insulin delivery system
    Antonios E Panteleon
    Medtronic MiniMed, 18000 Devonshire Rd, Northridge, CA 91325, USA
    Diabetes 55:1995-2000. 2006
    ..1 +/- 0.6, 9.6 +/- 1.0, and 8.5 +/- 0.6 mmol/l, respectively; P < 0.05). The data demonstrate that closed-loop insulin delivery using the subcutaneous site can provide stable glycemic control within a range of gain...
  13. ncbi The role of the independent variable to glucose sensor calibration
    Antonios E Panteleon
    Medtronic MiniMed, Inc, Northridge, California, USA
    Diabetes Technol Ther 5:401-10. 2003
    ....
  14. ncbi Effect of puberty on the pharmacodynamic and pharmacokinetic properties of insulin pump therapy in youth with type 1 diabetes
    Karena L Swan
    Section of Pediatric Endocrinology, Yale University, New Haven, Connecticut 06520, USA
    Diabetes Care 31:44-6. 2008