Amorsolo L Suguitan

Summary

Affiliation: MedImmune Vaccines
Country: USA

Publications

  1. pmc The influence of the multi-basic cleavage site of the H5 hemagglutinin on the attenuation, immunogenicity and efficacy of a live attenuated influenza A H5N1 cold-adapted vaccine virus
    Amorsolo L Suguitan
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rm 3E13C 1, 33 North Drive, MSC 3203, Bethesda, MD 20892 3203, USA
    Virology 395:280-8. 2009
  2. pmc The multibasic cleavage site of the hemagglutinin of highly pathogenic A/Vietnam/1203/2004 (H5N1) avian influenza virus acts as a virulence factor in a host-specific manner in mammals
    Amorsolo L Suguitan
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    J Virol 86:2706-14. 2012
  3. pmc Live, attenuated influenza A H5N1 candidate vaccines provide broad cross-protection in mice and ferrets
    Amorsolo L Suguitan
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Med 3:e360. 2006
  4. pmc Eurasian-origin gene segments contribute to the transmissibility, aerosol release, and morphology of the 2009 pandemic H1N1 influenza virus
    Seema S Lakdawala
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Pathog 7:e1002443. 2011
  5. pmc Antigenic fingerprinting of H5N1 avian influenza using convalescent sera and monoclonal antibodies reveals potential vaccine and diagnostic targets
    Surender Khurana
    Division of Viral Products, Center for Biologics Evaluation and Research CBER, Food and Drug Administration, Bethesda, Maryland, USA
    PLoS Med 6:e1000049. 2009

Collaborators

Detail Information

Publications5

  1. pmc The influence of the multi-basic cleavage site of the H5 hemagglutinin on the attenuation, immunogenicity and efficacy of a live attenuated influenza A H5N1 cold-adapted vaccine virus
    Amorsolo L Suguitan
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rm 3E13C 1, 33 North Drive, MSC 3203, Bethesda, MD 20892 3203, USA
    Virology 395:280-8. 2009
    ....
  2. pmc The multibasic cleavage site of the hemagglutinin of highly pathogenic A/Vietnam/1203/2004 (H5N1) avian influenza virus acts as a virulence factor in a host-specific manner in mammals
    Amorsolo L Suguitan
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    J Virol 86:2706-14. 2012
    ..Thus, the contribution of H5 HA MBS to the virulence of the HPAI H5N1 virus varies among mammalian hosts and is most significant in mice and ferrets and less remarkable in nonhuman primates...
  3. pmc Live, attenuated influenza A H5N1 candidate vaccines provide broad cross-protection in mice and ferrets
    Amorsolo L Suguitan
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Med 3:e360. 2006
    ....
  4. pmc Eurasian-origin gene segments contribute to the transmissibility, aerosol release, and morphology of the 2009 pandemic H1N1 influenza virus
    Seema S Lakdawala
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Pathog 7:e1002443. 2011
    ..We have demonstrated that the viruses are released into exhaled air to varying degrees and a constellation of genes influences the transmissibility of the pH1N1 virus...
  5. pmc Antigenic fingerprinting of H5N1 avian influenza using convalescent sera and monoclonal antibodies reveals potential vaccine and diagnostic targets
    Surender Khurana
    Division of Viral Products, Center for Biologics Evaluation and Research CBER, Food and Drug Administration, Bethesda, Maryland, USA
    PLoS Med 6:e1000049. 2009
    ..Characterizing the B cell responses in convalescent individuals could help in the design of future vaccines and therapeutics...