- Development of a novel ectonucleotidase assay suitable for high-throughput screeningKRIS F SACHSENMEIER
MedImmune, LLC, Gaithersburg, MD, USA
J Biomol Screen 17:993-8. 2012..This multiwell plate-based assay facilitates the screening of potential ectonucleotidase antagonists and is unaffected by the presence of contaminating phosphate molecules present in screening samples...
- Combining phenotypic and proteomic approaches to identify membrane targets in a 'triple negative' breast cancer cell typeSteven Rust
MedImmune, Granta Park, Cambridge, CB21 6GH, UK
Mol Cancer 12:11. 2013..In this study, the MDA-MB-231 cell line was selected for membranome survey as it is a 'triple negative' breast cancer cell line, which represents a cancer subtype that is aggressive and has few treatment options...