Brandon W Higgs

Summary

Affiliation: MedImmune Vaccines
Country: USA

Publications

  1. ncbi Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway
    Brandon W Higgs
    Translational Sciences, MedImmune, One MedImmune Way, Gaithersburg, MD 20878, USA
    Ann Rheum Dis 70:2029-36. 2011
  2. ncbi Identification of activated cytokine pathways in the blood of systemic lupus erythematosus, myositis, rheumatoid arthritis, and scleroderma patients
    Brandon W Higgs
    Translational Sciences, MedImmune, LLC, Gaithersburg, MD 20878, USA
    Int J Rheum Dis 15:25-35. 2012
  3. ncbi Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus
    Yihong Yao
    MedImmune, Gaithersburg, Maryland 20878, USA
    Arthritis Rheum 60:1785-96. 2009
  4. ncbi Use of type I interferon-inducible mRNAs as pharmacodynamic markers and potential diagnostic markers in trials with sifalimumab, an anti-IFNα antibody, in systemic lupus erythematosus
    Yihong Yao
    MedImmune, Translational Sciences, One MedImmune Way, Gaithersburg, MD 20878, USA
    Arthritis Res Ther 12:S6. 2010
  5. ncbi Altered expression of insulin receptor isoforms in breast cancer
    Jiaqi Huang
    MedImmune, LLC, Gaithersburg, Maryland, United States of America
    PLoS ONE 6:e26177. 2011
  6. ncbi Genomic signatures characterize leukocyte infiltration in myositis muscles
    Wei Zhu
    Translational Sciences, MedImmune, LLC, Gaithersburg, MD 20878, USA
    BMC Med Genomics 5:53. 2012
  7. ncbi A whole genome transcriptional analysis of the early immune response induced by live attenuated and inactivated influenza vaccines in young children
    Wei Zhu
    MedImmune, Translational Sciences, Gaithersburg, MD 20878, USA
    Vaccine 28:2865-76. 2010
  8. ncbi Type I interferon: potential therapeutic target for psoriasis?
    Yihong Yao
    MedImmune, Inc, Gaithersburg, Maryland, United States of America
    PLoS ONE 3:e2737. 2008

Collaborators

Detail Information

Publications8

  1. ncbi Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway
    Brandon W Higgs
    Translational Sciences, MedImmune, One MedImmune Way, Gaithersburg, MD 20878, USA
    Ann Rheum Dis 70:2029-36. 2011
    ....
  2. ncbi Identification of activated cytokine pathways in the blood of systemic lupus erythematosus, myositis, rheumatoid arthritis, and scleroderma patients
    Brandon W Higgs
    Translational Sciences, MedImmune, LLC, Gaithersburg, MD 20878, USA
    Int J Rheum Dis 15:25-35. 2012
    ....
  3. ncbi Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus
    Yihong Yao
    MedImmune, Gaithersburg, Maryland 20878, USA
    Arthritis Rheum 60:1785-96. 2009
    ..e., granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-10 (IL-10), tumor necrosis factor alpha (TNFalpha), and IL-1beta, in SLE...
  4. ncbi Use of type I interferon-inducible mRNAs as pharmacodynamic markers and potential diagnostic markers in trials with sifalimumab, an anti-IFNα antibody, in systemic lupus erythematosus
    Yihong Yao
    MedImmune, Translational Sciences, One MedImmune Way, Gaithersburg, MD 20878, USA
    Arthritis Res Ther 12:S6. 2010
    ....
  5. ncbi Altered expression of insulin receptor isoforms in breast cancer
    Jiaqi Huang
    MedImmune, LLC, Gaithersburg, Maryland, United States of America
    PLoS ONE 6:e26177. 2011
    ....
  6. ncbi Genomic signatures characterize leukocyte infiltration in myositis muscles
    Wei Zhu
    Translational Sciences, MedImmune, LLC, Gaithersburg, MD 20878, USA
    BMC Med Genomics 5:53. 2012
    ....
  7. ncbi A whole genome transcriptional analysis of the early immune response induced by live attenuated and inactivated influenza vaccines in young children
    Wei Zhu
    MedImmune, Translational Sciences, Gaithersburg, MD 20878, USA
    Vaccine 28:2865-76. 2010
    ....
  8. ncbi Type I interferon: potential therapeutic target for psoriasis?
    Yihong Yao
    MedImmune, Inc, Gaithersburg, Maryland, United States of America
    PLoS ONE 3:e2737. 2008
    ..To better understand the pathogenesis of this disease and identify potential mediators, we used whole genome array analysis to profile paired lesional and nonlesional psoriatic skin and skin from healthy donors...