Deborah L Clarke

Summary

Affiliation: MedImmune Vaccines
Country: USA

Publications

  1. pmc TNFα and IFNγ synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-κB, and the transcriptional coactivator CREB-binding protein
    Deborah L Clarke
    Nottingham Respiratory Biomedical Research Unit, City Hospital, University of Nottingham, Nottingham NG5 1PB, United Kingdom
    J Biol Chem 285:29101-10. 2010
  2. pmc Transcriptional regulation of monocyte chemotactic protein-1 release by endothelin-1 in human airway smooth muscle cells involves NF-kappaB and AP-1
    Amy M Sutcliffe
    Nottingham Respiratory Biomedical Research Unit, University of Nottingham, City Hospital, Nottingham NG5 1PB, UK
    Br J Pharmacol 157:436-50. 2009
  3. ncbi request reprint PKCbetaII augments NF-kappaB-dependent transcription at the CCL11 promoter via p300/CBP-associated factor recruitment and histone H4 acetylation
    Deborah L Clarke
    Division of Respiratory Medicine, University of Nottingham, City Hospital, Nottingham, United Kingdom
    J Immunol 181:3503-14. 2008

Collaborators

Detail Information

Publications3

  1. pmc TNFα and IFNγ synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-κB, and the transcriptional coactivator CREB-binding protein
    Deborah L Clarke
    Nottingham Respiratory Biomedical Research Unit, City Hospital, University of Nottingham, Nottingham NG5 1PB, United Kingdom
    J Biol Chem 285:29101-10. 2010
    ....
  2. pmc Transcriptional regulation of monocyte chemotactic protein-1 release by endothelin-1 in human airway smooth muscle cells involves NF-kappaB and AP-1
    Amy M Sutcliffe
    Nottingham Respiratory Biomedical Research Unit, University of Nottingham, City Hospital, Nottingham NG5 1PB, UK
    Br J Pharmacol 157:436-50. 2009
    ..We studied the effect of ET-1 on expression of the chemokine, monocyte chemotactic protein-1 (MCP-1), in primary cultures of human airway smooth muscle cells...
  3. ncbi request reprint PKCbetaII augments NF-kappaB-dependent transcription at the CCL11 promoter via p300/CBP-associated factor recruitment and histone H4 acetylation
    Deborah L Clarke
    Division of Respiratory Medicine, University of Nottingham, City Hospital, Nottingham, United Kingdom
    J Immunol 181:3503-14. 2008
    ..These data suggest a novel important biological role for PKCbetaIotaIota in NF-kappaB-mediated CCL11 transcription by p/CAF activation and histone H4 acetylation...