Hongwei Yu

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. pmc Intraganglionic AAV6 results in efficient and long-term gene transfer to peripheral sensory nervous system in adult rats
    Hongwei Yu
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
    PLoS ONE 8:e61266. 2013
  2. pmc Selective reconstitution of liver cholesterol biosynthesis promotes lung maturation but does not prevent neonatal lethality in Dhcr7 null mice
    Hongwei Yu
    Division of Endocrinology, Metabolism and Nutrition, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    BMC Dev Biol 7:27. 2007
  3. pmc Quantifying raft proteins in neonatal mouse brain by 'tube-gel' protein digestion label-free shotgun proteomics
    Hongwei Yu
    Division of Endocrinology, Metabolism and Nutrition, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Proteome Sci 5:17. 2007
  4. pmc Loss of apolipoprotein E exacerbates the neonatal lethality of the Smith-Lemli-Opitz syndrome mouse
    Curzio Solcà
    Division of Endocrinology, Metabolism and Clinical Nutrition, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Mol Genet Metab 91:7-14. 2007
  5. ncbi request reprint Partial rescue of neonatal lethality of Dhcr7 null mice by a nestin promoter-driven DHCR7 transgene expression
    Hongwei Yu
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, STR 541, 114 Doughty Street, Charleston, SC 29403, USA
    Brain Res Dev Brain Res 156:46-60. 2005
  6. pmc Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome
    Hongwei Yu
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, STR 541, 114 Doughty Street, Charleston, SC 29403, USA
    BMC Dev Biol 4:1. 2004
  7. pmc The missense mutation in Abcg5 gene in spontaneously hypertensive rats (SHR) segregates with phytosterolemia but not hypertension
    Jianliang Chen
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, STR 541, 114 Doughty Street, Charleston, SC 29403, USA
    BMC Genet 6:40. 2005
  8. pmc Lentiviral gene transfer into the dorsal root ganglion of adult rats
    Hongwei Yu
    Department of Anesthesiology, Medical College of Wisconsin, 8100 Watertown Plank Rd, Milwaukee, Wisconsin 53226, USA
    Mol Pain 7:63. 2011
  9. pmc Direct injection into the dorsal root ganglion: technical, behavioral, and histological observations
    Gregory Fischer
    Department of Anesthesiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    J Neurosci Methods 199:43-55. 2011
  10. pmc Ca²⁺-dependent regulation of Ca²⁺ currents in rat primary afferent neurons: role of CaMKII and the effect of injury
    Qingbo Tang
    Medical College of Wisconsin, Department of Anesthesiology, Milwaukee, Wisconsin 53226, USA
    J Neurosci 32:11737-49. 2012

Collaborators

Detail Information

Publications19

  1. pmc Intraganglionic AAV6 results in efficient and long-term gene transfer to peripheral sensory nervous system in adult rats
    Hongwei Yu
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
    PLoS ONE 8:e61266. 2013
    ..Intraganglionic delivery of AAV6 is more uniform and efficient compared to AAV8 in gene transfer to peripheral sensory neurons and their axonal processes...
  2. pmc Selective reconstitution of liver cholesterol biosynthesis promotes lung maturation but does not prevent neonatal lethality in Dhcr7 null mice
    Hongwei Yu
    Division of Endocrinology, Metabolism and Nutrition, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    BMC Dev Biol 7:27. 2007
    ....
  3. pmc Quantifying raft proteins in neonatal mouse brain by 'tube-gel' protein digestion label-free shotgun proteomics
    Hongwei Yu
    Division of Endocrinology, Metabolism and Nutrition, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Proteome Sci 5:17. 2007
    ..abstract:..
  4. pmc Loss of apolipoprotein E exacerbates the neonatal lethality of the Smith-Lemli-Opitz syndrome mouse
    Curzio Solcà
    Division of Endocrinology, Metabolism and Clinical Nutrition, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Mol Genet Metab 91:7-14. 2007
    ..Thus the murine data suggest that maternal loss of ApoE or Ldl-r function further exacerbates the neonatal lethality, suggesting they may play a role in maternal transfer of cholesterol to the embryo...
  5. ncbi request reprint Partial rescue of neonatal lethality of Dhcr7 null mice by a nestin promoter-driven DHCR7 transgene expression
    Hongwei Yu
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, STR 541, 114 Doughty Street, Charleston, SC 29403, USA
    Brain Res Dev Brain Res 156:46-60. 2005
    ..Another conclusion is that even small and subtle changes in the brain sterol metabolism were sufficient to enable rescue. These data also provide important clues as to the cause of the variable expressivity seen in SLOS...
  6. pmc Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome
    Hongwei Yu
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, STR 541, 114 Doughty Street, Charleston, SC 29403, USA
    BMC Dev Biol 4:1. 2004
    ..Although they have a number of biochemical and structural abnormalities, one cause of death is from apparent respiratory failure due to developmental pulmonary abnormalities...
  7. pmc The missense mutation in Abcg5 gene in spontaneously hypertensive rats (SHR) segregates with phytosterolemia but not hypertension
    Jianliang Chen
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, STR 541, 114 Doughty Street, Charleston, SC 29403, USA
    BMC Genet 6:40. 2005
    ....
  8. pmc Lentiviral gene transfer into the dorsal root ganglion of adult rats
    Hongwei Yu
    Department of Anesthesiology, Medical College of Wisconsin, 8100 Watertown Plank Rd, Milwaukee, Wisconsin 53226, USA
    Mol Pain 7:63. 2011
    ....
  9. pmc Direct injection into the dorsal root ganglion: technical, behavioral, and histological observations
    Gregory Fischer
    Department of Anesthesiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    J Neurosci Methods 199:43-55. 2011
    ..These findings demonstrate a method for selective injection of agents into single DRGs for anatomically restricted actions...
  10. pmc Ca²⁺-dependent regulation of Ca²⁺ currents in rat primary afferent neurons: role of CaMKII and the effect of injury
    Qingbo Tang
    Medical College of Wisconsin, Department of Anesthesiology, Milwaukee, Wisconsin 53226, USA
    J Neurosci 32:11737-49. 2012
    ..These findings indicate that I(Ca) in sensory neurons is subject to both CDI and CDF, and that hyperexcitability following injury-induced loss of CDF may result from diminished CaMKII activity...
  11. pmc A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol
    Eric L Klett
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, Charleston, SC 29403, USA
    BMC Med 2:5. 2004
    ..No phenotypic difference has yet been described in humans with complete defects in either ABCG5 or ABCG8. These proteins, based upon the defects in humans, are responsible for regulating dietary sterol entry and biliary sterol secretion...
  12. pmc The use of the Dhcr7 knockout mouse to accurately determine the origin of fetal sterols
    G S Tint
    Research Service, Department of Veterans Affairs Medical Center, East Orange, NJ 07018, USA
    J Lipid Res 47:1535-41. 2006
    ..The early fetal brain also appears to conserve cholesterol by keeping cholesterol 24-hydroxylase expression low until approximately E18...
  13. pmc Cross-sectional analysis of clinical and environmental isolates of Pseudomonas aeruginosa: biofilm formation, virulence, and genome diversity
    Nathan E Head
    Department of Microbiology, Immunology and Molecular Genetics, Joan C Edwards School of Medicine, Marshall University, Huntington, West Virginia 25704 9330, USA
    Infect Immun 72:133-44. 2004
    ..aeruginosa biodiversity could provide one cause for the variation of morbidity and mortality in CF. P. aeruginosa may possess undefined biofilm adhesins that are important to the development of an antibiofilm therapeutic target...
  14. ncbi request reprint Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration
    Jiangxue Wang
    Laboratory for Bio Environmental Effects of Nanomaterials and Nanosafety and Key Laboratory of Nuclear Analytical Techniques, National Center for NanoScience and Technology and Institute of High Energy Physics, Beijing 100080, PR China
    Toxicol Lett 168:176-85. 2007
    ..Biodistribution experiment showed that TiO(2) mainly retained in the liver, spleen, kidneys, and lung tissues, which indicated that TiO(2) particles could be transported to other tissues and organs after uptake by gastrointestinal tract...
  15. ncbi request reprint Antioxidative function and biodistribution of [Gd@C82(OH)22]n nanoparticles in tumor-bearing mice
    Jiangxue Wang
    Lab for Bio Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, P O Box 918, Beijing 100049, PR China
    Biochem Pharmacol 71:872-81. 2006
    ..The results suggest that [Gd@C82(OH)22]n nanoparticle treatment could regulate ROS production in vivo...
  16. pmc Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design
    Xiaoyu Xue
    Laboratory of Structural Biology, Life Sciences Building, Tsinghua University, Beijing 100084, China
    J Virol 82:2515-27. 2008
    ..The structure-based optimization of N3 has yielded two more efficacious lead compounds, N27 and H16, with potent inhibition against SARS-CoV M(pro)...
  17. ncbi request reprint Abrupt expression of TLR4 in TLR4-deficient macrophages imposes a selective disadvantage: genetic evidence for TLR4-dependent responses to endogenous, nonmicrobial stimuli
    Ellen F Cohn
    Graduate Program in Immunology and Microbial Pathogenesis, Weill Graduate School of Medical Sciences, Cornell University, New York, NY 10021, USA
    J Immunol 176:1185-94. 2006
    ....
  18. pmc Induction of macrophage-derived SLPI by Mycobacterium tuberculosis depends on TLR2 but not MyD88
    Aihao Ding
    Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10021, USA
    Immunology 116:381-9. 2005
    ..This induction signifies the presence of a TLR2-dependent but MyD88-independent M. tuberculosis signalling pathway, suggesting involvement of adaptor protein(s) other than MyD88 in M. tuberculosis-mediated induction of SLPI...
  19. ncbi request reprint Persistent infections and immunity in cystic fibrosis
    Hongwei Yu
    Department of Microbiology, Immunology and Molecular Genetics, Joan C Edwards School of Medicine at Marshall University, 1542 Spring Valley Drive, Huntington, WV 25704, USA
    Front Biosci 7:d442-57. 2002
    ..aeruginosa persistent infection phenotypes (biofilm and mucoidy) and an aerosol infection mouse model for CF. Genomic diversity of P. aeruginosa and its implications in the pathogenesis in CF will also be discussed...