M Wong-Riley

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. pmc Peripheral-central chemoreceptor interaction and the significance of a critical period in the development of respiratory control
    Margaret T T Wong-Riley
    Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Respir Physiol Neurobiol 185:156-69. 2013
  2. pmc Bigenomic regulation of cytochrome c oxidase in neurons and the tight coupling between neuronal activity and energy metabolism
    Margaret T T Wong-Riley
    Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Adv Exp Med Biol 748:283-304. 2012
  3. pmc Neurochemical and physiological correlates of a critical period of respiratory development in the rat
    Margaret T T Wong-Riley
    Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Respir Physiol Neurobiol 164:28-37. 2008
  4. ncbi request reprint Neurochemical development of brain stem nuclei involved in the control of respiration
    Margaret T T Wong-Riley
    Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Respir Physiol Neurobiol 149:83-98. 2005
  5. ncbi request reprint Quantitative immuno-electron microscopic analysis of nuclear respiratory factor 2 alpha and beta subunits: Normal distribution and activity-dependent regulation in mammalian visual cortex
    Margaret T T Wong-Riley
    Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee 53226, USA
    Vis Neurosci 22:1-18. 2005
  6. ncbi request reprint Photobiomodulation directly benefits primary neurons functionally inactivated by toxins: role of cytochrome c oxidase
    Margaret T T Wong-Riley
    Department of Cell Biology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    J Biol Chem 280:4761-71. 2005
  7. ncbi request reprint AMPA glutamate receptor subunit 2 in normal and visually deprived macaque visual cortex
    Margaret T T Wong-Riley
    Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee 53226, USA
    Vis Neurosci 19:563-73. 2002
  8. ncbi request reprint Human COX6A1 gene: promoter analysis, cDNA isolation and expression in the monkey brain
    M Wong-Riley
    Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Gene 247:63-75. 2000
  9. ncbi request reprint Human nuclear respiratory factor 2 alpha subunit cDNA: isolation, subcloning, sequencing, and in situ hybridization of transcripts in normal and monocularly deprived macaque visual system
    A Guo
    Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee 53226, USA
    J Comp Neurol 417:221-32. 2000
  10. ncbi request reprint Neurochemical organization of the macaque striate cortex: correlation of cytochrome oxidase with Na+K+ATPase, NADPH-diaphorase, nitric oxide synthase, and N-methyl-D-aspartate receptor subunit 1
    M Wong-Riley
    Department of Cellular Biology and Anatomy, Medical College of Wisconsin, Milwaukee 53226, USA
    Neuroscience 83:1025-45. 1998

Research Grants

  1. METABOLIC ORGANIZATION & REGULATION IN THE VISUAL CORTEX
    Margaret Wong Riley; Fiscal Year: 2002
  2. Neurochemical Organization of Brain Stem Respiratory Nuclei
    Margaret Wong Riley; Fiscal Year: 2007
  3. Neurochemical and metabolic regulation in the visual cortex
    Margaret Wong Riley; Fiscal Year: 2007
  4. Neurochemical Organization of Brain Stem Respiratory Nuclei
    Margaret Wong Riley; Fiscal Year: 2009
  5. Neurochemical Organization of Brain Stem Respiratory Nuclei
    MARGARET TT WONG RILEY; Fiscal Year: 2010
  6. METABOLIC PLASTICITY IN PRIMATE VISUAL CORTEX
    Margaret Wong Riley; Fiscal Year: 1993
  7. NEUROCHEMICAL ORGANIZATION & PLASTICITY IN VISUAL CORTEX
    Margaret Wong Riley; Fiscal Year: 1999
  8. Neurochemical and metabolic regulation in the visual cortex
    MARGARET TT WONG RILEY; Fiscal Year: 2010

Collaborators

Detail Information

Publications15

  1. pmc Peripheral-central chemoreceptor interaction and the significance of a critical period in the development of respiratory control
    Margaret T T Wong-Riley
    Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Respir Physiol Neurobiol 185:156-69. 2013
    ..Such denervation delays and prolongs the critical period, but does not eliminate it, suggesting that the critical period may be intrinsically and genetically determined...
  2. pmc Bigenomic regulation of cytochrome c oxidase in neurons and the tight coupling between neuronal activity and energy metabolism
    Margaret T T Wong-Riley
    Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Adv Exp Med Biol 748:283-304. 2012
    ..NRF-1, in addition, also regulates critical neurochemicals of glutamatergic synaptic transmission, thereby ensuring the tight coupling of energy metabolism and neuronal activity at the molecular level in neurons...
  3. pmc Neurochemical and physiological correlates of a critical period of respiratory development in the rat
    Margaret T T Wong-Riley
    Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Respir Physiol Neurobiol 164:28-37. 2008
    ..The critical period embodies a time of multi-system, multifaceted growth and adjustments. It is a plastic, transitional period that is also a part of the normal development of the respiratory system...
  4. ncbi request reprint Neurochemical development of brain stem nuclei involved in the control of respiration
    Margaret T T Wong-Riley
    Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Respir Physiol Neurobiol 149:83-98. 2005
    ..Relating these neurochemical changes to physiological responses in animals and to sudden infant death syndrome in humans will be a challenge for future research...
  5. ncbi request reprint Quantitative immuno-electron microscopic analysis of nuclear respiratory factor 2 alpha and beta subunits: Normal distribution and activity-dependent regulation in mammalian visual cortex
    Margaret T T Wong-Riley
    Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee 53226, USA
    Vis Neurosci 22:1-18. 2005
    ..The density of both subunits was much higher in the nucleus than in the cytoplasm for all neurons examined, again indicating that their major sites of cellular action is in the nucleus...
  6. ncbi request reprint Photobiomodulation directly benefits primary neurons functionally inactivated by toxins: role of cytochrome c oxidase
    Margaret T T Wong-Riley
    Department of Cell Biology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    J Biol Chem 280:4761-71. 2005
    ..The results are consistent with our hypothesis that the mechanism of photobiomodulation involves the up-regulation of cytochrome c oxidase, leading to increased energy metabolism in neurons functionally inactivated by toxins...
  7. ncbi request reprint AMPA glutamate receptor subunit 2 in normal and visually deprived macaque visual cortex
    Margaret T T Wong-Riley
    Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee 53226, USA
    Vis Neurosci 19:563-73. 2002
    ..The maintenance of GluR2 in these output layers is governed by visual input and neuronal activity, as monocular impulse blockade induced a down-regulation of this subunit in deprived ocular dominance columns...
  8. ncbi request reprint Human COX6A1 gene: promoter analysis, cDNA isolation and expression in the monkey brain
    M Wong-Riley
    Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Gene 247:63-75. 2000
    ..Monocular impulse blockade in adult monkeys induced a downregulation of COX6A1 expression in deprived visual neurons, suggesting that this subunit gene is regulated by neuronal activity...
  9. ncbi request reprint Human nuclear respiratory factor 2 alpha subunit cDNA: isolation, subcloning, sequencing, and in situ hybridization of transcripts in normal and monocularly deprived macaque visual system
    A Guo
    Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee 53226, USA
    J Comp Neurol 417:221-32. 2000
    ..These data indicate that, in the normal and visually deprived adult monkeys, NRF-2 alpha is regulated by neuronal activity at the transcriptional level...
  10. ncbi request reprint Neurochemical organization of the macaque striate cortex: correlation of cytochrome oxidase with Na+K+ATPase, NADPH-diaphorase, nitric oxide synthase, and N-methyl-D-aspartate receptor subunit 1
    M Wong-Riley
    Department of Cellular Biology and Anatomy, Medical College of Wisconsin, Milwaukee 53226, USA
    Neuroscience 83:1025-45. 1998
    ..These interactions impose a higher energy demand under normal conditions and are down-regulated by retinal impulse blockade...
  11. ncbi request reprint Developing neural crest cells in culture: correlation of cytochrome oxidase activity with SSEA-1 and dopamine-beta-hydroxylase immunoreactivity
    S Liu
    Department of Anatomy and Cellular Biology, Medical College of Wisconsin, Milwaukee 53226
    Brain Res 535:271-80. 1990
    ..In general, SSEA-1+ sensory neurons are much more C.O. reactive than DBH+ autonomic cells. This suggests that developing sensory neurons in culture may have higher spontaneous and/or synaptic activity than autonomic neurons...
  12. ncbi request reprint Cytochrome oxidase in Alzheimer's disease: biochemical, histochemical, and immunohistochemical analyses of the visual and other systems
    M Wong-Riley
    Department of Cellular Biology and Anatomy, Medical College of Wisconsin, Milwaukee 53226, USA
    Vision Res 37:3593-608. 1997
    ..Such hypometabolism may form the basis for not only deficits in higher cortical functions, but also a variety of visual dysfunctions known to occur in AD...
  13. ncbi request reprint Expression and regulation of NMDA receptor subunit R1 and neuronal nitric oxide synthase in cortical neuronal cultures: correlation with cytochrome oxidase
    C Zhang
    Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, WI 53226, USA
    J Neurocytol 28:525-39. 1999
    ..Our results demonstrate that NMDA receptors and nNOS do co-exist in a subset of neurons that have high CO activity and their expressions are under the control of neuronal activity...
  14. ncbi request reprint Photobiomodulation partially rescues visual cortical neurons from cyanide-induced apoptosis
    H L Liang
    Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Neuroscience 139:639-49. 2006
    ....
  15. pmc Excitatory-inhibitory imbalance in hypoglossal neurons during the critical period of postnatal development in the rat
    Xiu Ping Gao
    Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    J Physiol 589:1991-2006. 2011
    ..Thus, our results provide strong electrophysiological evidence for an excitatory-inhibitory imbalance in HMs during the critical period of postnatal development in rats that may have significant implications for SIDS...

Research Grants24

  1. METABOLIC ORGANIZATION & REGULATION IN THE VISUAL CORTEX
    Margaret Wong Riley; Fiscal Year: 2002
    ..Results from these studies are expected to provide insight into the molecular basis of metabolic responses of visual cortical neurons to changing functional demands. ..
  2. Neurochemical Organization of Brain Stem Respiratory Nuclei
    Margaret Wong Riley; Fiscal Year: 2007
    ....
  3. Neurochemical and metabolic regulation in the visual cortex
    Margaret Wong Riley; Fiscal Year: 2007
    ....
  4. Neurochemical Organization of Brain Stem Respiratory Nuclei
    Margaret Wong Riley; Fiscal Year: 2009
    ....
  5. Neurochemical Organization of Brain Stem Respiratory Nuclei
    MARGARET TT WONG RILEY; Fiscal Year: 2010
    ....
  6. METABOLIC PLASTICITY IN PRIMATE VISUAL CORTEX
    Margaret Wong Riley; Fiscal Year: 1993
    ....
  7. NEUROCHEMICAL ORGANIZATION & PLASTICITY IN VISUAL CORTEX
    Margaret Wong Riley; Fiscal Year: 1999
    ..These same analyses will be done following monocular deprivation to assess how activity might differentially regulate the neurochemical nature of synaptic connections in puff and interpuff regions. ..
  8. Neurochemical and metabolic regulation in the visual cortex
    MARGARET TT WONG RILEY; Fiscal Year: 2010
    ....