Harry T Whelan

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. ncbi request reprint NASA light-emitting diodes for the prevention of oral mucositis in pediatric bone marrow transplant patients
    Harry T Whelan
    Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    J Clin Laser Med Surg 20:319-24. 2002
  2. doi request reprint Practical model-based dose finding in early-phase clinical trials: optimizing tissue plasminogen activator dose for treatment of ischemic stroke in children
    Harry T Whelan
    Division of Pediatric Neurology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    Stroke 39:2627-36. 2008
  3. ncbi request reprint Therapeutic effect of near infrared (NIR) light on Parkinson's disease models
    Brendan J Quirk
    Department of Neurology, Medical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, USA
    Front Biosci (Elite Ed) 4:818-23. 2012
  4. doi request reprint Evaluation of the child with acute ataxia: a systematic review
    Harry T Whelan
    Department of Neurology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Pediatr Neurol 49:15-24. 2013
  5. ncbi request reprint High-grade glioma/glioblastoma multiforme: is there a role for photodynamic therapy?
    Harry T Whelan
    Hyperbaric Medicine, U S Navy Professional School Liaison, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    J Natl Compr Canc Netw 10:S31-4. 2012
  6. ncbi request reprint Effect of NASA light-emitting diode irradiation on molecular changes for wound healing in diabetic mice
    Harry T Whelan
    Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    J Clin Laser Med Surg 21:67-74. 2003
  7. pmc Pretreatment with near-infrared light via light-emitting diode provides added benefit against rotenone- and MPP+-induced neurotoxicity
    Rong Ying
    Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Brain Res 1243:167-73. 2008
  8. pmc Near-infrared photobiomodulation in an animal model of traumatic brain injury: improvements at the behavioral and biochemical levels
    Brendan J Quirk
    Department of Neurology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Photomed Laser Surg 30:523-9. 2012
  9. ncbi request reprint Photobiomodulation directly benefits primary neurons functionally inactivated by toxins: role of cytochrome c oxidase
    Margaret T T Wong-Riley
    Department of Cell Biology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    J Biol Chem 280:4761-71. 2005
  10. pmc Presumed hydrogen sulfide-mediated neurotoxicity after streptococcus anginosus group meningitis
    Sumit Verma
    Department of Neurology, Medical College of Wisconsin, Milwaukee, WI 53201 1997, USA
    Pediatr Infect Dis J 32:189-91. 2013

Research Grants

  1. NIR-LED Treatment for Parkinson's Disease
    HARRY WHELAN; Fiscal Year: 2007

Collaborators

Detail Information

Publications21

  1. ncbi request reprint NASA light-emitting diodes for the prevention of oral mucositis in pediatric bone marrow transplant patients
    Harry T Whelan
    Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    J Clin Laser Med Surg 20:319-24. 2002
    ..The purpose of this study was to determine the effects of prophylactic near-infrared light therapy from light-emitting diodes (LEDs) in pediatric bone marrow transplant (BMT) recipients...
  2. doi request reprint Practical model-based dose finding in early-phase clinical trials: optimizing tissue plasminogen activator dose for treatment of ischemic stroke in children
    Harry T Whelan
    Division of Pediatric Neurology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    Stroke 39:2627-36. 2008
    ..This article describes a Bayesian outcome-adaptive method for determining the best dose of an experimental agent and explains how this method was used to design a dose-finding trial for tPA in childhood...
  3. ncbi request reprint Therapeutic effect of near infrared (NIR) light on Parkinson's disease models
    Brendan J Quirk
    Department of Neurology, Medical College of Wisconsin, 8701 W Watertown Plank Rd, Milwaukee, WI 53226, USA
    Front Biosci (Elite Ed) 4:818-23. 2012
    ..Functional recovery of the animals, chemical and histological evidence, and delayed disease progression show the potential of NIR light in treating Parkinson's disease...
  4. doi request reprint Evaluation of the child with acute ataxia: a systematic review
    Harry T Whelan
    Department of Neurology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Pediatr Neurol 49:15-24. 2013
    ..Nuclear scan may be considered, however, there is insufficient evidence for additional body imaging. ..
  5. ncbi request reprint High-grade glioma/glioblastoma multiforme: is there a role for photodynamic therapy?
    Harry T Whelan
    Hyperbaric Medicine, U S Navy Professional School Liaison, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    J Natl Compr Canc Netw 10:S31-4. 2012
    ..With no clear standard of care for brain tumors, PDT may emerge as a potential alternative, although challenges regarding its clinical use remain and studies confirming its promise are necessary...
  6. ncbi request reprint Effect of NASA light-emitting diode irradiation on molecular changes for wound healing in diabetic mice
    Harry T Whelan
    Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    J Clin Laser Med Surg 21:67-74. 2003
    ..In this paper we present the effects of LED treatment on wounds in a genetically diabetic mouse model...
  7. pmc Pretreatment with near-infrared light via light-emitting diode provides added benefit against rotenone- and MPP+-induced neurotoxicity
    Rong Ying
    Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Brain Res 1243:167-73. 2008
    ..These data suggest that LED pretreatment is an effective adjunct preventative therapy in rescuing neurons from neurotoxins linked to PD...
  8. pmc Near-infrared photobiomodulation in an animal model of traumatic brain injury: improvements at the behavioral and biochemical levels
    Brendan J Quirk
    Department of Neurology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Photomed Laser Surg 30:523-9. 2012
    ....
  9. ncbi request reprint Photobiomodulation directly benefits primary neurons functionally inactivated by toxins: role of cytochrome c oxidase
    Margaret T T Wong-Riley
    Department of Cell Biology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    J Biol Chem 280:4761-71. 2005
    ..The results are consistent with our hypothesis that the mechanism of photobiomodulation involves the up-regulation of cytochrome c oxidase, leading to increased energy metabolism in neurons functionally inactivated by toxins...
  10. pmc Presumed hydrogen sulfide-mediated neurotoxicity after streptococcus anginosus group meningitis
    Sumit Verma
    Department of Neurology, Medical College of Wisconsin, Milwaukee, WI 53201 1997, USA
    Pediatr Infect Dis J 32:189-91. 2013
    ..We describe putative focal hydrogen sulfide neurotoxicity after Streptococcus constellatus meningitis, treated with adjunctive sodium nitrite and hyperbaric oxygen therapy...
  11. doi request reprint The use of hyperbaric oxygen for treating delayed radiation injuries in gynecologic malignancies: a review of literature and report of radiation injury incidence
    Scott Allen
    Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Support Care Cancer 20:2467-72. 2012
    ....
  12. doi request reprint Amelioration of oral mucositis pain by NASA near-infrared light-emitting diodes in bone marrow transplant patients
    Brian D Hodgson
    Pediatric Dentistry, Marquette University School of Dentistry, 1801 W Wisconsin Ave, Rm 326, Milwaukee, WI 53233, USA
    Support Care Cancer 20:1405-15. 2012
    ....
  13. pmc Near infrared light protects cardiomyocytes from hypoxia and reoxygenation injury by a nitric oxide dependent mechanism
    Rong Zhang
    Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53326, USA
    J Mol Cell Cardiol 46:4-14. 2009
    ..Taken together these data provide evidence for protection against hypoxia and reoxygenation injury in cardiomyocytes by NIR in a manner that is dependent upon NO derived from NOS and non-NOS sources...
  14. ncbi request reprint Hyperbaric oxygen therapy of cerebral ischemia
    Ann K Helms
    Medical College of Wisconsin, Milwaukee, Wisc 53226, USA
    Cerebrovasc Dis 20:417-26. 2005
    ..Hyperbaric oxygen (HBO) therapy of cerebral ischemia has been evaluated in a number of human and animal studies; however, there is presently no consensus on its efficacy...
  15. ncbi request reprint Innate immunity for biodefense: a strategy whose time has come
    Catherine Amlie-Lefond
    Department of Neurology, Medial College of Wisconsin, WI 53226, USA
    J Allergy Clin Immunol 116:1334-42. 2005
    ..Toll-like receptor agonists caused cytokine production in all subjects tested, but genetic polymorphism reduced the response to IFN in African American subjects...
  16. pmc Antithrombotic treatment in neonatal cerebral sinovenous thrombosis: results of the International Pediatric Stroke Study
    Lori C Jordan
    Department of Neurology, Division of Pediatric Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Pediatr 156:704-10, 710.e1-710.e2. 2010
    ..To identify predictors of antithrombotic treatment in neonates with cerebral sinovenous thrombosis (CSVT) in a large multinational study...
  17. ncbi request reprint Clinical and experimental applications of NIR-LED photobiomodulation
    Kristina D Desmet
    Department of Clinical Laboratory Sciences, University of Wisconsin Milwaukee, 53226, USA
    Photomed Laser Surg 24:121-8. 2006
    ..NIR-LED light represents a novel, noninvasive, therapeutic intervention for the treatment of numerous diseases linked to mitochondrial dysfunction...
  18. ncbi request reprint 670 nanometer light treatment attenuates dioxin toxicity in the developing chick embryo
    Ronnie L Yeager
    School of Public and Environmental Affairs, Indiana University, Bloomington, IN 47405, USA
    J Biochem Mol Toxicol 20:271-8. 2006
    ..The effective attenuation of TCDD-induced embryo toxicity by LED treatment could extend to mitigating the effects of other teratogens that induce oxidative and energy stress...
  19. ncbi request reprint A preliminary investigation into light-modulated replication of nanobacteria and heart disease
    Andrei P Sommer
    Central Institute of Biomedical Engineering, University of Ulm, 89081 Ulm, Germany
    J Clin Laser Med Surg 21:231-5. 2003
    ..The purpose of this preliminary study is to evaluate the effect of various wavelengths of light on nanobacteria (NB)...
  20. ncbi request reprint Effects of 670-nm phototherapy on development
    Ronnie L Yeager
    School of Public and Environmental Affairs, Indiana University, Bloomington, IN 47405, USA
    Photomed Laser Surg 23:268-72. 2005
    ..The objective of the present study was to assess the survival and hatching success of chickens (Gallus gallus) exposed in ovo to far-red (670-nm) LED therapy...
  21. ncbi request reprint Hyperbaric oxygen therapy of acute ischemic stroke
    Ann K Helms
    Stroke 38:1137; author reply 1138-9. 2007

Research Grants1

  1. NIR-LED Treatment for Parkinson's Disease
    HARRY WHELAN; Fiscal Year: 2007
    ....