Research Topics
| Brian J WellsSummaryAffiliation: Medical University of South Carolina Country: USA Publications
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Detail Information
Publications
Using the electronic medical record to enhance the use of combination drugsBrian J Wells
Department of Family Medicine, Medical University of South Carolina, Charleston, SC 29425, USA
Am J Med Qual 18:147-9. 2003..30. Point-of-care reminders are a simple and effective tool for quality-improvement interventions. Combination drugs may play an important role in controlling medication costs...
Antibiotics for the secondary prevention of ischemic heart disease: a meta-analysis of randomized controlled trialsBrian J Wells
Department of Family Medicine, Medical University of South Carolina, Charleston, SC 29245, USA
Arch Intern Med 164:2156-61. 2004..The numerous clinical trials that have studied the use of antibiotics in the secondary prevention of IHD have had conflicting results...
The combined effect of transferrin saturation and low density lipoprotein on mortalityBrian J Wells
Department of Family Medicine, Medical University of South Carolina, Charleston 29425, USA
Fam Med 36:324-9. 2004..This study examined whether adults with elevated iron, as measured by transferrin saturation (TS), and elevated LDL are at an increased risk for mortality...
Iron, cholesterol, and the risk of cancer in an 18-year cohortBrian J Wells
Department of Family Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Asian Pac J Cancer Prev 6:505-9. 2005..51 (CI 1.10-2.08) and 1.61 (CI 1.07-2.43), respectively. These results support the theory that the iron induced oxidation of serum lipids is important in the pathogenesis of cancer...
Cholesterol, transferrin saturation, and the development of dementia and Alzheimer's disease: results from an 18-year population-based cohortArch G Mainous
Department of Family Medicine, Medical University of South Carolina, 295 Calhoun Street, Charleston, SC 29425, USA
Fam Med 37:36-42. 2005..This study examined the relationship between transferrin saturation (TS) and cholesterol to see if both are necessary to increase the risk for the subsequent development of AD...
Smoking, fibrinogen and cancer mortalityCharles J Everett
Department of Family Medicine, Medical University of South Carolina, Charleston, SC 29425, USA
J Natl Med Assoc 99:328-33. 2007..Smoking carries high risks of cancer mortality for African Americans. A factor that needs to be considered in the overall assessment of risk is fibrinogen level, which has been linked to angiogenesis and metastases of tumors...
Iron, lipids, and risk of cancer in the Framingham Offspring cohortArch G Mainous
Department of Family Medicine, Medical University of South Carolina, 295 Calhoun Street, Charleston, SC 29425, USA
Am J Epidemiol 161:1115-22. 2005..82, 95% CI: 1.50, 5.28; 14 cases). The results suggest that elevated serum iron levels coupled with either high VLDL-C or low HDL-C appear to interact to increase cancer risk in this cohort...
Association between dietary arginine and C-reactive proteinBrian J Wells
Department of Family Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
Nutrition 21:125-30. 2005..We investigated whether a dietary intake of arginine is associated with risk for cardiovascular disease as determined by levels of C-reactive protein (CRP)...
End-of-life issues and spiritual historiesDana E King
Department of Family Medicine, Medical University of South Carolina, Charleston, SC 29406, USA
South Med J 96:391-3. 2003..Patients facing end-of-life issues have spiritual concerns that may have an impact on their medical decision-making...
Association of ferritin and lipids with C-reactive proteinArch G Mainous
Department of Family Medicine, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Am J Cardiol 93:559-62. 2004..71; 95% CI 1.28 to 2.27). These results suggest that both iron and lipids induce inflammation. Future research needs to focus on preventive medicine to decrease iron in patients with elevated lipids...
Prostate cancer and sexually transmitted diseases: a meta-analysisMarcia L Taylor
Department of Family Medicine, Medical University of South Carolina, Charleston 29425, USA
Fam Med 37:506-12. 2005..In this meta-analysis, we examine the current epidemiological evidence for the association between specific sexually transmitted diseases (STDs) and prostate cancer...
Are thyroid peroxidase antibodies associated with cardiovascular disease risk in patients with subclinical hypothyroidism?Brian J Wells
Department of Family Medicine at the Cleveland Clinic Foundation, Strongsville, Ohio, USA
Clin Endocrinol (Oxf) 62:580-4. 2005..Thyroid peroxidase antibodies (TPOAb) are more common in persons with SCH. The purpose of this study was to evaluate whether the presence of (TPOAb) in people with SCH is associated with markers of cardiovascular disease...
Use of feeding tubes in elderly patients with dementiaBrian J Wells
Am Fam Physician 66:1836, 1838. 2002
Statins and cancer: a meta-analysis of case-control studiesMarcia L Taylor
Lexington Medical Center, Lexington, South Carolina, USA
Eur J Cancer Prev 17:259-68. 2008..On the basis of these results, randomized control trials with longer follow-up times than previously used are warranted...
