Xiaoling Wang

Summary

Affiliation: Medical College of Georgia
Country: USA

Publications

  1. pmc Genetic influences on daytime and night-time blood pressure: similarities and differences
    Xiaoling Wang
    Department of Pediatrics, Medical College of Georgia, Georgia Prevention Institute, Augusta, GA 30912, USA
    J Hypertens 27:2358-64. 2009
  2. ncbi request reprint Ethnic and gender differences in ambulatory blood pressure trajectories: results from a 15-year longitudinal study in youth and young adults
    Xiaoling Wang
    Medical College of Georgia, Georgia Prevention Institute, Bldg HS 1640, Augusta, GA 30912, USA
    Circulation 114:2780-7. 2006
  3. pmc Genetic influences on heart rate variability at rest and during stress
    Xiaoling Wang
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, Georgia, USA
    Psychophysiology 46:458-65. 2009
  4. pmc Heritability of insulin sensitivity and lipid profile depend on BMI: evidence for gene-obesity interaction
    X Wang
    Georgia Prevention Institute, Medical College of Georgia, Building HS 1640, Augusta, GA 30912, USA
    Diabetologia 52:2578-84. 2009
  5. pmc Obesity related methylation changes in DNA of peripheral blood leukocytes
    Xiaoling Wang
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, GA, USA
    BMC Med 8:87. 2010
  6. pmc Genetic influence on blood pressure measured in the office, under laboratory stress and during real life
    Xiaoling Wang
    Department of Pediatrics, Medical College of Georgia, Georgia Prevention Institute, Augusta, GA, USA
    Hypertens Res 34:239-44. 2011
  7. pmc A longitudinal study of blood pressure variability in African-American and European American youth
    Zhibin Li
    Department of Pediatrics, Georgia Prevention Institute, Medical College of Georgia, Augusta 30912, USA
    J Hypertens 28:715-22. 2010
  8. pmc Stress-induced sodium excretion: a new intermediate phenotype to study the early genetic etiology of hypertension?
    Dongliang Ge
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, Georgia, USA
    Hypertension 53:262-9. 2009
  9. ncbi request reprint The G protein-coupled receptor kinase 4 gene affects blood pressure in young normotensive twins
    Haidong Zhu
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Building HS 1640, Augusta, GA 30912 3715, USA
    Am J Hypertens 19:61-6. 2006
  10. ncbi request reprint Effects of angiotensinogen and angiotensin II type I receptor genes on blood pressure and left ventricular mass trajectories in multiethnic youth
    Xiaoling Wang
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, 30912, USA
    Twin Res Hum Genet 9:393-402. 2006

Collaborators

Detail Information

Publications52

  1. pmc Genetic influences on daytime and night-time blood pressure: similarities and differences
    Xiaoling Wang
    Department of Pediatrics, Medical College of Georgia, Georgia Prevention Institute, Augusta, GA 30912, USA
    J Hypertens 27:2358-64. 2009
    ..To examine whether the genetic influences on blood pressure (BP) during night-time are different from those during daytime and the extent to which they depend on ethnicity or sex...
  2. ncbi request reprint Ethnic and gender differences in ambulatory blood pressure trajectories: results from a 15-year longitudinal study in youth and young adults
    Xiaoling Wang
    Medical College of Georgia, Georgia Prevention Institute, Bldg HS 1640, Augusta, GA 30912, USA
    Circulation 114:2780-7. 2006
    ..Cross-sectional studies demonstrated ethnic and gender differences in ambulatory blood pressure patterns, but little is known about the longitudinal development of these differences...
  3. pmc Genetic influences on heart rate variability at rest and during stress
    Xiaoling Wang
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, Georgia, USA
    Psychophysiology 46:458-65. 2009
    ..23 for HF. The findings suggest that, independent of ethnicity and gender, HRV regulation at rest and under stress is largely influenced by the same genes with a small but significant contribution of stress-specific genetic effects...
  4. pmc Heritability of insulin sensitivity and lipid profile depend on BMI: evidence for gene-obesity interaction
    X Wang
    Georgia Prevention Institute, Medical College of Georgia, Building HS 1640, Augusta, GA 30912, USA
    Diabetologia 52:2578-84. 2009
    ..On an aggregate level, gene-obesity interactions are expected to result in different heritability estimates at different obesity levels. However, this hypothesis has never been tested...
  5. pmc Obesity related methylation changes in DNA of peripheral blood leukocytes
    Xiaoling Wang
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, GA, USA
    BMC Med 8:87. 2010
    ..Because of emerging evidence that immune responses are epigenetically regulated, we hypothesized that DNA methylation changes are involved in obesity induced immune dysfunction and aimed to identify these changes...
  6. pmc Genetic influence on blood pressure measured in the office, under laboratory stress and during real life
    Xiaoling Wang
    Department of Pediatrics, Medical College of Georgia, Georgia Prevention Institute, Augusta, GA, USA
    Hypertens Res 34:239-44. 2011
    ..However, significant genetic components specific to each BP measurement also exist. These findings suggest that partly different genes or sets of genes contribute to BP regulation in different conditions...
  7. pmc A longitudinal study of blood pressure variability in African-American and European American youth
    Zhibin Li
    Department of Pediatrics, Georgia Prevention Institute, Medical College of Georgia, Augusta 30912, USA
    J Hypertens 28:715-22. 2010
    ..However, little is known about blood pressure variability changes with age and its possible sociodemographic, anthropometric, and genetic moderators...
  8. pmc Stress-induced sodium excretion: a new intermediate phenotype to study the early genetic etiology of hypertension?
    Dongliang Ge
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, Georgia, USA
    Hypertension 53:262-9. 2009
    ..36 in whites and 0.39 in blacks. In summary, this study establishes Delta U(Na)V and stress U(Na)V as heritable phenotypes that may be used to study the genetic etiology of early hypertension development...
  9. ncbi request reprint The G protein-coupled receptor kinase 4 gene affects blood pressure in young normotensive twins
    Haidong Zhu
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Building HS 1640, Augusta, GA 30912 3715, USA
    Am J Hypertens 19:61-6. 2006
    ..The present study evaluated the impact of the GRK4 gene variants on BP levels in normotensive adolescents and young adults...
  10. ncbi request reprint Effects of angiotensinogen and angiotensin II type I receptor genes on blood pressure and left ventricular mass trajectories in multiethnic youth
    Xiaoling Wang
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, 30912, USA
    Twin Res Hum Genet 9:393-402. 2006
    ..A protective AGTR1 haplotype for LVM was also identified...
  11. pmc A longitudinal study in youth of heart rate variability at rest and in response to stress
    Zhibin Li
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, GA 30912, USA
    Int J Psychophysiol 73:212-7. 2009
    ..Few longitudinal studies have examined ethnic and sex differences, predictors and tracking stabilities of heart rate variability (HRV) at rest and in response to stress in youths and young adults...
  12. ncbi request reprint Influence of the eNOS gene on development of blood pressure and left ventricular mass: longitudinal findings in multiethnic youth
    Haidong Zhu
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, GA 30912 3710, USA
    Pharmacogenet Genomics 15:669-75. 2005
    ..To evaluate the impact of the endothelial nitric oxide synthase (eNOS) gene on longitudinal development of blood pressure (BP) and left ventricular mass (LVM) from childhood into early adulthood...
  13. pmc A 15-year longitudinal study on ambulatory blood pressure tracking from childhood to early adulthood
    Zhibin Li
    Department of Pediatrics, Medical College of Georgia, Georgia Prevention Institute, Augusta, GA, USA
    Hypertens Res 32:404-10. 2009
    ..001). No significant ethnic differences were observed. The high tracking stability of 24-h ABP highlights the importance of using ambulatory BP monitoring in both research and clinical settings...
  14. ncbi request reprint Effects of dopamine receptor type 1 and Gs protein alpha subunit gene polymorphisms on blood pressure at rest and in response to stress
    Yanhui Lu
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, GA 30912 3715, USA
    Am J Hypertens 19:832-6. 2006
    ..Therefore, we investigated whether the A-48G polymorphism of the DRD1 gene and the T393C polymorphism of the Gs protein alpha subunit (GNAS) gene influenced BP levels at rest and in response to stress...
  15. ncbi request reprint The G protein-coupled receptor kinase 4 gene modulates stress-induced sodium excretion in black normotensive adolescents
    Haidong Zhu
    Department of Pediatrics, Georgia Prevention Institute, Medical College of Georgia, Augusta, GA 30912 3715, USA
    Pediatr Res 60:440-2. 2006
    ..The 65L allele of the GRK4 gene is associated with stress-induced U(Na)V reduction, suggesting impaired sodium handling in affected black youth...
  16. ncbi request reprint Genetic and environmental determinants of lipid profile in black and white youth: a study of four candidate genes
    Catherine L Davis
    Georgia Prevention Institute, Medical College of Georgia, Augusta, Georgia 30912, USA
    Ethn Dis 15:568-77. 2005
    ..To identify genotypes and gene-environment interactions, which may explain ethnic differences on lipid profile in Black and White youth...
  17. ncbi request reprint Endothelin-1 gene and progression of blood pressure and left ventricular mass: longitudinal findings in youth
    Yanbin Dong
    Georgia Prevention Institute Department of Pediatrics, Medical College of Georgia, Augusta 30912 3710, USA
    Hypertension 44:884-90. 2004
    ..In summary, our results uncover a sex-specific protective effect of variation in the ET-1 gene on the progression of hypertension risk, and a SES-specific effect on risk of developing left ventricular hypertrophy in multiethnic youth...
  18. pmc A genome-wide methylation study on essential hypertension in young African American males
    Xiaoling Wang
    Georgia Prevention Institute, Department of Pediatrics, Georgia Health Sciences University, Augusta, Georgia, United States of America
    PLoS ONE 8:e53938. 2013
    ..Based on the recent studies that highlight the involvement of inflammation in the development of hypertension, we hypothesize that changes in DNA methylation of leukocytes are involved in the pathogenesis of hypertension...
  19. pmc Leukocyte telomere length in healthy Caucasian and African-American adolescents: relationships with race, sex, adiposity, adipokines, and physical activity
    Haidong Zhu
    Department of Pediatrics, Georgia Prevention Institute, Medical College of Georgia, Augusta, GA 30912 3715, USA
    J Pediatr 158:215-20. 2011
    ..To examine the relationships of race, sex, adiposity, adipokines, and physical activity to telomere length in adolescents...
  20. pmc Heritability of arterial stiffness in black and white American youth and young adults
    Dongliang Ge
    Georgia Prevention Institute, Department of Pediatrics, Department of Pediatrics, Medical College of Georgia, Augusta, Georgia, USA
    Am J Hypertens 20:1065-72. 2007
    ..Our objectives were to examine the heritability of arterial stiffness measured as pulse-wave velocity (PWV), and its dependence on ethnicity, gender, and blood pressure (BP)...
  21. ncbi request reprint The Georgia Cardiovascular Twin Study: influence of genetic predisposition and chronic stress on risk for cardiovascular disease and type 2 diabetes
    Dongliang Ge
    Department of Pediatrics, Georgia Prevention Institute, Medical College of Georgia, Augusta, GA 30912, USA
    Twin Res Hum Genet 9:965-70. 2006
    ....
  22. pmc A genome-wide methylation study of severe vitamin D deficiency in African American adolescents
    Haidong Zhu
    Department of Pediatrics, Georgia Prevention Institute, Georgia Health Sciences University, Augusta, GA 30912, USA
    J Pediatr 162:1004-9.e1. 2013
    ..To test the hypothesis that changes in DNA methylation are involved in vitamin D deficiency-related immune cell regulation using an unbiased genome-wide approach combined with a genomic and epigenomic integrative approach...
  23. ncbi request reprint Update on G-protein polymorphisms in hypertension
    Haidong Zhu
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, 1120 15th Street, HS 1640, Augusta, GA 30912 3715, USA
    Curr Hypertens Rep 8:23-9. 2006
    ..In this review, in conjunction with our own research, we bring readers up to date on the latest developments of GNB3 polymorphisms in the field of hypertension...
  24. pmc Prostasin: a possible candidate gene for human hypertension
    Haidong Zhu
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, Georgia, USA
    Am J Hypertens 21:1028-33. 2008
    ..This study aimed to evaluate whether the human prostasin gene is a novel candidate gene underlying blood pressure (BP) elevation...
  25. ncbi request reprint Genetic and environmental influences on anger expression, John Henryism, and stressful life events: the Georgia Cardiovascular Twin Study
    Xiaoling Wang
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, GA 30912, USA
    Psychosom Med 67:16-23. 2005
    ..To examine the genetic and/or environmental origin of variation and covariation of perceived stressful life events and two stress-related coping styles, anger expression and John Henryism...
  26. ncbi request reprint Ethnic differences and heritability of heart rate variability in African- and European American youth
    Xiaoling Wang
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, Georgia, USA
    Am J Cardiol 96:1166-72. 2005
    ..High heritability estimates for HRV measures were observed, and no differences in HRV heritability estimates were noted for ethnicity or gender...
  27. pmc DNA Methylation of the LY86 Gene is Associated With Obesity, Insulin Resistance, and Inflammation
    Shaoyong Su
    Georgia Prevention Center, Georgia Regents University, Augusta, GA, USA
    Twin Res Hum Genet 17:183-91. 2014
    ..001), and inflammatory markers (p < .001). Conclusion: By focusing on recent GWAS findings in genome-wide methylation profiles, we identified a solid association between LY86 gene DNA methylation and obesity. ..
  28. pmc A genome-wide methylation study on obesity: differential variability and differential methylation
    Xiaojing Xu
    Georgia Prevention Institute, Department of Pediatrics, Georgia Regents University, Augusta, GA, USA
    Epigenetics 8:522-33. 2013
    ..Future studies on the epigenetics of obesity will benefit from both statistics based on means and statistics based on variances. ..
  29. pmc Genetic and environmental influences on blood pressure variability: a study in twins
    Xiaojing Xu
    Department of Pediatrics, Georgia Prevention Institute, Georgia Health Sciences University, Augusta, Georgia 30912, USA
    J Hypertens 31:690-7. 2013
    ..In this study, we examined the relative influence of genetic and environmental sources of variance of BPV and the extent to which it may depend on race or sex in young twins...
  30. ncbi request reprint Obesity reveals an association between blood pressure and the G-protein beta3-subunit gene: a study of female dizygotic twins
    Yanbin Dong
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, Georgia, USA
    Pharmacogenetics 14:419-27. 2004
    ....
  31. doi request reprint Urinary prostasin excretion is associated with adiposity in nonhypertensive African-American adolescents
    De huang Guo
    Department of Pediatrics, Georgia Prevention Institute, Georgia Regents University, Augusta, Georgia, USA
    Pediatr Res 74:206-10. 2013
    ..Our specific aim was to explore whether there is a relationship between adiposity and urinary prostasin excretion at the population level...
  32. doi request reprint A method to detect differentially methylated loci with next-generation sequencing
    Hongyan Xu
    Department of Biostatistics and Epidemiology, Georgia Health Sciences University, Augusta, GA 30912 4900, USA
    Genet Epidemiol 37:377-82. 2013
    ..It has good power and is computationally efficient. Finally, we apply the test to our NGS data on chronic lymphocytic leukemia. The results indicate that it is a promising and practical test...
  33. pmc Beyond genome-wide association studies: new strategies for identifying genetic determinants of hypertension
    Xiaoling Wang
    Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, GA, USA
    Curr Hypertens Rep 13:442-51. 2011
    ....
  34. ncbi request reprint Angiotensin II type I receptor gene and myocardial infarction: tagging SNPs and haplotype based association study. The Beijing atherosclerosis study
    Shaoyong Su
    The Division of Population Genetics and Prevention, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Beijing 100037, China
    Pharmacogenetics 14:673-81. 2004
    ..The present study aimed to assess the effect of haplotype variation in angiotensin II type I receptor (AGTR1) gene on the risk of myocardial infarction (MI) in Chinese males...
  35. ncbi request reprint Heritabilities of lipids in young European American and African American twins
    Anastasia Iliadou
    Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Twin Res Hum Genet 8:492-8. 2005
    ..In this first twin study on lipids to include AAs, no ethnic differences in heritability were found except for LDL, where AAs exhibited higher estimates...
  36. ncbi request reprint Linkage analysis of 2q14-q23 and 5q32 with blood pressure quantitative traits in Chinese sib pairs
    Dongliang Ge
    Division of Population Genetics and Prevention, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China
    J Hypertens 21:305-10. 2003
    ..The current study aimed to examine the linkage of qualitative and blood pressure quantitative traits in essential hypertension with these genomic regions in a large sample of Chinese hypertensive families...
  37. ncbi request reprint Extensive association analysis between polymorphisms of PON gene cluster with coronary heart disease in Chinese Han population
    Xiaoling Wang
    Division of Population Genetics, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing
    Arterioscler Thromb Vasc Biol 23:328-34. 2003
    ..An extensive association analysis of PON gene cluster (PONs) with coronary heart disease (CHD) was performed in Chinese Han population...
  38. ncbi request reprint Thrombospondin-4 A387P polymorphism is not associated with coronary artery disease and myocardial infarction in the Chinese Han population
    Xiaoyang Zhou
    Division of Population Genetics and Prevention, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 BeiLiShi Rd, Beijing 100037, People s Republic of China
    Clin Sci (Lond) 106:495-500. 2004
    ..Additional investigations should be performed in populations at different risk of coronary events in order to elucidate further the possible contribution of this polymorphism to cardiovascular disease...
  39. ncbi request reprint Genetic and environmental factors associated with plasma paraoxonase activity in healthy Chinese
    Xiaoling Wang
    Division of Population Genetics, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
    Int J Mol Med 13:445-50. 2004
    ..The results illustrate the complexity of polymorphism-phenotype associations. The observed interactions constitute concrete examples of gene-environment and environment-environment interactions...
  40. pmc A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms
    Gane Ka Shu Wong
    Beijing Institute of Genomics of Chinese Academy of Sciences, Beijing Genomics Institute, Beijing Proteomics Institute, Beijing 101300, China
    Nature 432:717-22. 2004
    ..In fact, most of the SNPs originated before domestication, and there is little evidence of selective sweeps for adaptive alleles on length scales greater than 100 kilobases...
  41. ncbi request reprint Proopiomelanocortin gene variants are associated with serum leptin and body fat in a normal female population
    Yuanneng Chen
    Department of Clinical Developmental Sciences, St George s Hospital Medical School, London, UK
    Eur J Hum Genet 13:772-80. 2005
    ..78 (P<0.0001)). Associations of BMI, weight and total fat with SNPs in regions flanking the POMC gene in this powerful study suggest that regulation of POMC expression may be influential in determining body weight...
  42. ncbi request reprint Protein tyrosine phosphatase-1B gene PTPN1: selection of tagging single nucleotide polymorphisms and association with body fat, insulin sensitivity, and the metabolic syndrome in a normal female population
    Nicola J Spencer-Jones
    Department of Clinical Developmental Sciences, St George s, University of London, London, UK
    Diabetes 54:3296-304. 2005
    ..PTPN1 variants appear to contribute to central fat and metabolic syndrome traits, secondary to their effect on insulin sensitivity...
  43. ncbi request reprint Plasminogen activator inhibitor-1 gene: selection of tagging single nucleotide polymorphisms and association with coronary heart disease
    Shaoyong Su
    Division of Population Genetics and Prevention, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
    Arterioscler Thromb Vasc Biol 26:948-54. 2006
    ..To explore the effect of plasminogen activator inhibitor-1 (PAI-1) gene variations on the risk of coronary heart disease (CHD) in Chinese Han population...
  44. ncbi request reprint Waist-to-height ratio and BMI predict different cardiovascular risk factors in Chinese children
    Weili Yan
    Diabetes Care 29:2760-1. 2006
  45. pmc Adiponectin gene ADIPOQ SNP associations with serum adiponectin in two female populations and effects of SNPs on promoter activity
    Theodosios Kyriakou
    Nutritional Sciences Division, King s College London, Franklin Wilkins Building, London, SE1 9NH, UK
    J Hum Genet 53:718-27. 2008
    ..2 kb of the ADIPOQ promoter region was cloned in a luciferase reporter plasmid, and the four haplotypes were transfected in differentiated 3T3-L1 adipocytes. No significant allelic effects on promoter activity were found...
  46. doi request reprint Waist circumference cutoff points in school-aged Chinese Han and Uygur children
    Weili Yan
    Division of Epidemiology and Biostatistics, School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang, China
    Obesity (Silver Spring) 16:1687-92. 2008
    ..To examine the distribution of age- and gender-specific waist circumference (WC) and to identify optimal cutoffs for predicting cardiovascular (CV) risk factors in Chinese Han and Uygur children...
  47. pmc Thoc1/Hpr1/p84 is essential for early embryonic development in the mouse
    Xiaoling Wang
    Department of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Mol Cell Biol 26:4362-7. 2006
    ..While Hpr1p is not essential for the viability of unicellular yeasts, the orthologous Thoc1 protein is required for viability of the early mouse embryo...
  48. ncbi request reprint Factor V gene G1691A mutation, prothrombin gene G20210A mutation, and MTHFR gene C677T mutation are not risk factors for pulmonary thromboembolism in Chinese population
    Yanhui Lu
    Division of Cardio Pulmonary Circulation, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100037, Beijing, People s Republic of China
    Thromb Res 106:7-12. 2002
    ....
  49. ncbi request reprint Ethnic differences in heart rate variability: does ultralow-frequency heart rate variability really measure autonomic tone?
    Julian F Thayer
    Am Heart J 152:e27. 2006
  50. ncbi request reprint STAT5a/PPARgamma pathway regulates involucrin expression in keratinocyte differentiation
    Xiuju Dai
    Department of Dermatology, Ehime University School of Medicine, Ehime, Japan
    J Invest Dermatol 127:1728-35. 2007
    ..This report provides early evidence of a major role for STAT5a in the differentiation of keratinocytes, where it contributes to involucrin expression by activating the PPARgamma signal...
  51. pmc Common STAT3 variants are not associated with obesity or insulin resistance in female twins
    Yalda Jamshidi
    Nutrition Food and Health Research Centre, King s College London, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NH, United Kingdom
    Obesity (Silver Spring) 15:1634-9. 2007
    ..Although defective STAT3 action results in obesity and insulin resistance in animal models, we failed to establish any indicative associations with common SNPs in this human study...
  52. pmc An allelic series for studying the mouse Thoc1 gene
    Xiaoling Wang
    Department of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Genesis 45:32-7. 2007
    ..However, these mice express less pThoc1 than wild type mice and exhibit a dwarf phenotype. The dwarf phenotype can be detected in mid-gestation embryos, suggesting that Thoc1 is also required later in embryonic and postnatal development...

Research Grants2

  1. Identifying genes related to heart rate variability at rest and during stress
    Xiaoling Wang; Fiscal Year: 2007
    ..Low HRV increases the risk of cardiovascular disease. We will look for variants in the genes involved in the regulation of HRV to see if they explain individual differences in HRV observed in the population. ..