Joachim D Uys

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. ncbi Glutamate: the new frontier in pharmacotherapy for cocaine addiction
    Joachim D Uys
    Department of Neurosciences, Medical University of South Carolina, 173 Ashley Ave, Charleston, SC 29425, USA
    CNS Neurol Disord Drug Targets 7:482-91. 2008
  2. ncbi Matrix-assisted laser desorption/ionization tissue profiling of secretoneurin in the nucleus accumbens shell from cocaine-sensitized rats
    Joachim D Uys
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    J Mass Spectrom 45:97-103. 2010
  3. ncbi S-glutathionylated serine proteinase inhibitors as plasma biomarkers in assessing response to redox-modulating drugs
    Christina L Grek
    Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Cancer Res 72:2383-93. 2012
  4. ncbi AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis
    Kathryn J Reissner
    Departments of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Neurosci 31:5648-58. 2011
  5. ncbi Ablation of the ATP-binding cassette transporter, Abca2 modifies response to estrogen-based therapies
    Jody T Mack
    Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC 29425, USA
    Biomed Pharmacother 66:403-8. 2012
  6. ncbi Cocaine-induced adaptations in cellular redox balance contributes to enduring behavioral plasticity
    Joachim D Uys
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Neuropsychopharmacology 36:2551-60. 2011

Collaborators

Detail Information

Publications6

  1. ncbi Glutamate: the new frontier in pharmacotherapy for cocaine addiction
    Joachim D Uys
    Department of Neurosciences, Medical University of South Carolina, 173 Ashley Ave, Charleston, SC 29425, USA
    CNS Neurol Disord Drug Targets 7:482-91. 2008
    ..Future pharmacotherapy may focus on manipulating signal transduction proteins and pathways, which include Homer/N-methyl-D-aspartic acid complexes, to provide effective treatment for cocaine addiction...
  2. ncbi Matrix-assisted laser desorption/ionization tissue profiling of secretoneurin in the nucleus accumbens shell from cocaine-sensitized rats
    Joachim D Uys
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    J Mass Spectrom 45:97-103. 2010
    ..In addition, the distribution of m/z 3653 in the nucleus accumbens was determined by MALDI tissue imaging, and the increased expression of its precursor protein, secretogranin II, was verified by immunoblotting...
  3. ncbi S-glutathionylated serine proteinase inhibitors as plasma biomarkers in assessing response to redox-modulating drugs
    Christina L Grek
    Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Cancer Res 72:2383-93. 2012
    ..There is potential for S-glutathionylated serpins A1 and A3 to act as pharmacodynamic biomarkers for evaluation of patient response to drugs that target redox pathways...
  4. ncbi AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis
    Kathryn J Reissner
    Departments of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Neurosci 31:5648-58. 2011
    ....
  5. ncbi Ablation of the ATP-binding cassette transporter, Abca2 modifies response to estrogen-based therapies
    Jody T Mack
    Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC 29425, USA
    Biomed Pharmacother 66:403-8. 2012
    ..0%). Taken together, these data indicate that ABCA2 deficiency renders mice more sensitive to EMP treatment-induced effects implying that the transporter has a role in regulating EMP transport and/or metabolism...
  6. ncbi Cocaine-induced adaptations in cellular redox balance contributes to enduring behavioral plasticity
    Joachim D Uys
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Neuropsychopharmacology 36:2551-60. 2011
    ..Together, these data indicate that cocaine-induced oxidative stress induces changes in GSTpi that contribute to cocaine-induced behavioral plasticity...