Himanshu Upadhyaya

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. ncbi request reprint Impact of substance use disorder on ADHD and its treatment
    Timothy E Wilens
    Department of Pediatric Psychopharmacology, Massachusetts General Hospital, USA
    J Clin Psychiatry 68:e20. 2007
  2. ncbi request reprint Managing attention-deficit/hyperactivity disorder in the presence of substance use disorder
    Himanshu P Upadhyaya
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, USA
    J Clin Psychiatry 68:23-30. 2007
  3. ncbi request reprint Reactivity to in vivo smoking cues in older adolescent cigarette smokers
    Himanshu P Upadhyaya
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Nicotine Tob Res 8:135-40. 2006
  4. ncbi request reprint Neuroendocrine and behavioral responses to dopaminergic agonists in adolescents with alcohol abuse
    Himanshu P Upadhyaya
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA
    Psychopharmacology (Berl) 166:95-101. 2003
  5. ncbi request reprint Psychiatric disorders and cigarette smoking among child and adolescent psychiatry inpatients
    Himanshu P Upadhyaya
    Departments of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Am J Addict 12:144-52. 2003
  6. ncbi request reprint Reactivity to smoking cues in adolescent cigarette smokers
    Himanshu P Upadhyaya
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, P O Box 250861, Charleston, SC 29425, USA
    Addict Behav 29:849-56. 2004
  7. ncbi request reprint A practical clinical approach to the treatment of nicotine dependence in adolescents
    Himanshu Upadhyaya
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, USA
    J Am Acad Child Adolesc Psychiatry 44:942-6. 2005
  8. ncbi request reprint Attention-deficit/hyperactivity disorder, medication treatment, and substance use patterns among adolescents and young adults
    Himanshu P Upadhyaya
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, USA
    J Child Adolesc Psychopharmacol 15:799-809. 2005
  9. ncbi request reprint Stress reactivity: biological and subjective responses to the cold pressor and Trier Social stressors
    Aimee L McRae
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Hum Psychopharmacol 21:377-85. 2006
  10. ncbi request reprint Reactivity to nicotine cues over repeated cue reactivity sessions
    Steven D LaRowe
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina MUSC, Charleston SC, 29425, USA
    Addict Behav 32:2888-99. 2007

Research Grants

Detail Information

Publications36

  1. ncbi request reprint Impact of substance use disorder on ADHD and its treatment
    Timothy E Wilens
    Department of Pediatric Psychopharmacology, Massachusetts General Hospital, USA
    J Clin Psychiatry 68:e20. 2007
    ..SUD also complicates the diagnosis of adult ADHD. Fortunately, pharmacologic treatment of ADHD does not appear to increase the risk for development of SUD in ADHD patients...
  2. ncbi request reprint Managing attention-deficit/hyperactivity disorder in the presence of substance use disorder
    Himanshu P Upadhyaya
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, USA
    J Clin Psychiatry 68:23-30. 2007
    ..Clinical recommendations for treating this dual diagnosis include using nonstimulant agents or extended-release stimulant formulations in conjunction with psychosocial therapies to treat both the ADHD and the SUD...
  3. ncbi request reprint Reactivity to in vivo smoking cues in older adolescent cigarette smokers
    Himanshu P Upadhyaya
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Nicotine Tob Res 8:135-40. 2006
    ..Findings from this study suggest that adolescent smokers may show patterns of responding to smoking cues similar to those of adult smokers. Implications for future laboratory studies with adolescent smokers are discussed...
  4. ncbi request reprint Neuroendocrine and behavioral responses to dopaminergic agonists in adolescents with alcohol abuse
    Himanshu P Upadhyaya
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA
    Psychopharmacology (Berl) 166:95-101. 2003
    ..Dopaminergic systems are involved in the pathophysiology of alcohol use disorders, but there is little research investigating the role of these systems in adolescents...
  5. ncbi request reprint Psychiatric disorders and cigarette smoking among child and adolescent psychiatry inpatients
    Himanshu P Upadhyaya
    Departments of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Am J Addict 12:144-52. 2003
    ..56,older age=1.3, depressive disorders=4.02, conduct disorder (CD)=12.96, cannabis abuse/dependence=24.6. Hence, cigarette smoking is highly prevalent but underdiagnosed in this population...
  6. ncbi request reprint Reactivity to smoking cues in adolescent cigarette smokers
    Himanshu P Upadhyaya
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, P O Box 250861, Charleston, SC 29425, USA
    Addict Behav 29:849-56. 2004
    ..Findings suggest that adolescents smokers show similar patterns of responding to smoking cues as adult smokers, although effects were not particularly robust in this sample and subjective effects were dependent on cue order...
  7. ncbi request reprint A practical clinical approach to the treatment of nicotine dependence in adolescents
    Himanshu Upadhyaya
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, USA
    J Am Acad Child Adolesc Psychiatry 44:942-6. 2005
  8. ncbi request reprint Attention-deficit/hyperactivity disorder, medication treatment, and substance use patterns among adolescents and young adults
    Himanshu P Upadhyaya
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, USA
    J Child Adolesc Psychopharmacol 15:799-809. 2005
    ..The aim of this study was to examine the relationship between current active attention-deficit/hyperactivity disorder (ADHD) symptoms, medication treatment, and substance use patterns among college students...
  9. ncbi request reprint Stress reactivity: biological and subjective responses to the cold pressor and Trier Social stressors
    Aimee L McRae
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Hum Psychopharmacol 21:377-85. 2006
    ..The results suggest that the TSST results in a greater HPA response than the CPT; however, the CPT may have utility in diagnostically heterogeneous patients...
  10. ncbi request reprint Reactivity to nicotine cues over repeated cue reactivity sessions
    Steven D LaRowe
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina MUSC, Charleston SC, 29425, USA
    Addict Behav 32:2888-99. 2007
    ..Results suggest that, under the described experimental parameters, craving can be reliably elicited over repeated cue reactivity sessions...
  11. pmc Is attention deficit hyperactivity disorder (ADHD) symptom severity associated with tobacco use?
    Himanshu P Upadhyaya
    Division of Clinical Neurosciences, Department of Psychiatry, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Addict 17:195-8. 2008
    ..The results suggest that the number of ADHD symptoms is proportionally associated with tobacco, alcohol, and marijuana use...
  12. pmc Tolerability and effects of oral Delta9-tetrahydrocannabinol in older adolescents with marijuana use disorders
    Kevin M Gray
    Youth Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, P O Box 250861, Charleston, South Carolina 29425, USA
    Pharmacol Biochem Behav 91:67-70. 2008
    ..However, no studies have included adolescent participants. This double-blind laboratory study investigated the tolerability and effects of oral THC in a group of older adolescents with marijuana use disorders...
  13. pmc Cue reactivity in young marijuana smokers: a preliminary investigation
    Kevin M Gray
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425, USA
    Psychol Addict Behav 22:582-6. 2008
    ..The procedure appears to elicit cue reactivity among adolescents and young adults with cannabis use disorders and should be further evaluated and refined with a larger sample. Implications for future studies are discussed...
  14. pmc Laboratory-based, cue-elicited craving and cue reactivity as predictors of naturally occurring smoking behavior
    Matthew J Carpenter
    Medical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Hollings Cancer Center, 86 Jonathan Lucas St PO Box 250955 Charleston, SC 29425, USA
    Addict Behav 34:536-41. 2009
    ..Our findings highlight important methodological and theoretical considerations for cue reactivity research...
  15. doi request reprint Menstrual phase effects on smoking cessation: a pilot feasibility study
    Matthew J Carpenter
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Womens Health (Larchmt) 17:293-301. 2008
    ..Our objectives were to preliminarily test the effect of timing of quit attempts for smoking cessation relative to menstrual cycle and to identify methodological procedures that could guide subsequent, larger clinical trials...
  16. pmc Menstrual cycle and cue reactivity in women smokers
    Kevin M Gray
    Youth Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, P O Box 250861, Charleston, SC 29425, USA
    Nicotine Tob Res 12:174-8. 2010
    ..The present study sought to explore the influence of menstrual cycle phase on reactivity to smoking in vivo and stressful imagery cues in a sample of non-treatment-seeking women smokers...
  17. pmc Effects of gender and cigarette smoking on reactivity to psychological and pharmacological stress provocation
    Sudie E Back
    Department of Psychiatry, Clinical Neuroscience Division, Medical University of South Carolina, 67 President Street, PO Box 250861, Charleston, SC, USA
    Psychoneuroendocrinology 33:560-8. 2008
    ..In addition, there is some evidence for a more robust neuroendocrine and physiologic response to acute laboratory stress in women as compared to men...
  18. ncbi request reprint Menstrual cycle phase effects on nicotine withdrawal and cigarette craving: a review
    Matthew J Carpenter
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Nicotine Tob Res 8:627-38. 2006
    ..Further research is necessary to replicate these findings, but they may suggest the need for focused cessation treatment during the luteal phase or quit attempts that are well timed relative to specific menstrual phases...
  19. pmc Assessment of nicotine dependence among adolescent and young adult smokers: a comparison of measures
    Matthew J Carpenter
    Department of Psychiatry, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, USA
    Addict Behav 35:977-82. 2010
    ..We further examined the FTND by removing the one item on cigarettes smoked per day...
  20. ncbi request reprint The impact of alcohol dependence and posttraumatic stress disorder on cold pressor task response
    Kathleen T Brady
    Division of Clinical Neuroscience, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Box 250861, Charleston, South Carolina 29425, USA
    J Stud Alcohol 67:700-6. 2006
    ..The objective of this study was to investigate HPA axis reactivity to the cold pressor task (CPT) among individuals with alcohol dependence, PTSD, and comorbid alcohol dependence and PTSD...
  21. ncbi request reprint Advances in diagnosis of adolescent substance abuse
    Kevin M Gray
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, PO Box 250861, Charleston, 29425, USA
    Adolesc Med Clin 17:411-25. 2006
    ..The authors provide a synopsis of recent advances and important issues in this area and propose a stepwise, evidence-based approach to evaluation of substance abuse in adolescents...
  22. ncbi request reprint Cold pressor task reactivity: predictors of alcohol use among alcohol-dependent individuals with and without comorbid posttraumatic stress disorder
    Kathleen T Brady
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Alcohol Clin Exp Res 30:938-46. 2006
    ..This study investigated the relationship between subjective and neuroendocrine stress reactivity to the cold pressor task (CPT) and prospective alcohol use among individuals with alcohol dependence, with and without comorbid PTSD...
  23. pmc Attention-deficit/hyperactivity disorder confounds nicotine withdrawal self-report in adolescent smokers
    Kevin M Gray
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Addict 19:325-31. 2010
    ..Smoking research, particularly among adolescents in whom ADHD is so common, should carefully consider the complex issue of comorbid ADHD and nicotine dependence...
  24. pmc Bupropion SR and contingency management for adolescent smoking cessation
    Kevin M Gray
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA
    J Subst Abuse Treat 40:77-86. 2011
    ..Combined bupropion SR and CM appears efficacious, at least in the short-term, for adolescent smoking cessation and may be superior to either intervention alone...
  25. pmc Contingency management in community programs treating adolescent substance abuse: a feasibility study
    Therese K Killeen
    College of Medicine, Institute of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA
    J Child Adolesc Psychiatr Nurs 25:33-41. 2012
    ..Adolescent substance abuse remains a public health problem, and more effective treatment approaches are needed...
  26. ncbi request reprint Bupropion SR in adolescents with comorbid ADHD and nicotine dependence: a pilot study
    Himanshu P Upadhyaya
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    J Am Acad Child Adolesc Psychiatry 43:199-205. 2004
    ..This open-label pilot study was designed to examine the feasibility and preliminary tolerability of bupropion SR in adolescents with nicotine dependence...
  27. ncbi request reprint Cigarette smoking and psychiatric comorbidity in children and adolescents
    Himanshu P Upadhyaya
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    J Am Acad Child Adolesc Psychiatry 41:1294-305. 2002
    ..To review the current state of knowledge of psychiatric comorbidity in adolescent cigarette smokers...
  28. ncbi request reprint Managing ADHD in the presence of comorbid substance use disorder
    Himanshu P Upadhyaya
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, USA
    J Clin Psychiatry 68:e15. 2007
  29. ncbi request reprint PTSD and the HPA axis: differences in response to the cold pressor task among individuals with child vs. adult trauma
    Elizabeth J Santa Ana
    Division of Clinical Neuroscience, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, P O Box 250861, Charleston, SC 29425, USA
    Psychoneuroendocrinology 31:501-9. 2006
    ..The findings reveal differences in the neuroendocrine response to the CPT in individuals with PTSD compared to control subjects, and differences in PTSD subjects when examined by age of index trauma...
  30. pmc Tobacco smoking in individuals with attention-deficit hyperactivity disorder: epidemiology and pharmacological approaches to cessation
    Kevin M Gray
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina, USA
    CNS Drugs 23:661-8. 2009
    ....
  31. pmc The role of cystine-glutamate exchange in nicotine dependence in rats and humans
    Lori A Knackstedt
    Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Biol Psychiatry 65:841-5. 2009
    ....
  32. pmc Daily stressor sensitivity, abuse effects, and cocaine use in cocaine dependence
    Angela E Waldrop
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Box 250861, Charleston, SC 29425, USA
    Addict Behav 32:3015-25. 2007
    ..Reactivity to cocaine cues was related to daily hassle sensitivity among women only. Limitations and implications of the findings are discussed...
  33. pmc The impact of loss to follow-up on hypothesis tests of the treatment effect for several statistical methods in substance abuse clinical trials
    Sarra L Hedden
    Department of Biostatistics, Bioinformatics and Epidemiology, Medical University of South Carolina, Charleston, SC 29425, USA
    J Subst Abuse Treat 37:54-63. 2009
    ..e., "ignorable"). If the missing data are presumed to be nonignorable, a sensitivity analysis is recommended...
  34. ncbi request reprint Diagnosing ADHD in adults with substance use disorder: DSM-IV criteria and differential diagnosis
    Frances R Levin
    New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, USA
    J Clin Psychiatry 68:e18. 2007
    ..If proper attention is paid to age-appropriate symptoms of ADHD, and careful longitudinal data are obtained from patients presenting with ADHD or SUD, proper treatment can be given to patients with these comorbid disorders...
  35. ncbi request reprint Do patients with ADHD have a harder time quitting cigarettes?
    Himanshu P Upadhyaya
    J Am Acad Child Adolesc Psychiatry 45:891. 2006
  36. ncbi request reprint The effect of stimulant treatment for ADHD on later substance abuse and the potential for medication misuse, abuse, and diversion
    Stephen V Faraone
    Department of Pediatric Psychopharmacology, Massachusetts General Hospital, Boston, USA
    J Clin Psychiatry 68:e28. 2007
    ..As a result, extended-release products and different formulations, such as lisdexamfetamine dimesylate (LDX), are less likely to be misused and diverted and may have lower abuse potential...

Research Grants6

  1. Combined Pharmaco/Behavior Therapy in Adolescent Smokers
    KEVIN GRAY; Fiscal Year: 2007
    ..Results of the study will help improve the current state of knowledge for smoking cessation in adolescent smokers. ..