Radu Tutuian

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. ncbi request reprint Effects of position on oesophageal function: studies using combined manometry and multichannel intraluminal impedance
    R Tutuian
    Division of Gastroenterology, Medical University of South Carolina, Charleston 29425, USA
    Neurogastroenterol Motil 15:63-7. 2003
  2. ncbi request reprint Clarification of the esophageal function defect in patients with manometric ineffective esophageal motility: studies using combined impedance-manometry
    Radu Tutuian
    Division of Gastroeneterology Hepatology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Clin Gastroenterol Hepatol 2:230-6. 2004
  3. ncbi request reprint Rumination documented by using combined multichannel intraluminal impedance and manometry
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, Charleston, 29425, USA
    Clin Gastroenterol Hepatol 2:340-3. 2004
  4. ncbi request reprint Nocturnal acid breakthrough: pH, drugs and bugs
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Eur J Gastroenterol Hepatol 16:441-3. 2004
  5. ncbi request reprint Gastroesophageal reflux disease: natural history and long-term medical and surgical outcomes
    Radu Tutuian
    Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Clin Cornerstone 5:51-7; discussion 58-60. 2003
  6. ncbi request reprint Diagnosis of laryngopharyngeal reflux
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Curr Opin Otolaryngol Head Neck Surg 12:174-9. 2004
  7. ncbi request reprint Disposable balloon-based oesophageal motility catheters: comparison with solid-state transducers
    R Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, Charleston, SC 29425, USA
    Neurogastroenterol Motil 17:453-7. 2005
  8. ncbi request reprint Reflux monitoring: role of combined multichannel intraluminal impedance and pH
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, 96 Jonathan Lucas Street, 210 CSB, Charleston, SC 29425, USA
    Gastrointest Endosc Clin N Am 15:361-71. 2005
  9. ncbi request reprint Multichannel intraluminal impedance: general principles and technical issues
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, 96 Jonathan Lucas Street, 210 CSB, Charleston, SC 29425, USA
    Gastrointest Endosc Clin N Am 15:257-64. 2005
  10. ncbi request reprint Esophageal function testing with combined multichannel intraluminal impedance and manometry: multicenter study in healthy volunteers
    Radu Tutuian
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Clin Gastroenterol Hepatol 1:174-82. 2003

Collaborators

Detail Information

Publications67

  1. ncbi request reprint Effects of position on oesophageal function: studies using combined manometry and multichannel intraluminal impedance
    R Tutuian
    Division of Gastroenterology, Medical University of South Carolina, Charleston 29425, USA
    Neurogastroenterol Motil 15:63-7. 2003
    ..Combined MII-OM identifies and quantifies the effects of gravity on the dichotomy between specific pressures measured by OM and function assessed as transit measured by MII...
  2. ncbi request reprint Clarification of the esophageal function defect in patients with manometric ineffective esophageal motility: studies using combined impedance-manometry
    Radu Tutuian
    Division of Gastroeneterology Hepatology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Clin Gastroenterol Hepatol 2:230-6. 2004
    ..The aim of our study is to evaluate esophageal bolus transit in patients with manometric patterns of ineffective esophageal motility (IEM)...
  3. ncbi request reprint Rumination documented by using combined multichannel intraluminal impedance and manometry
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, Charleston, 29425, USA
    Clin Gastroenterol Hepatol 2:340-3. 2004
    ..The opportunity to review these documented changes visually helps to make the patient aware of the functional aspects of the condition, avoiding unwarranted therapies and providing the opportunity to reinforce behavioral modifications...
  4. ncbi request reprint Nocturnal acid breakthrough: pH, drugs and bugs
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Eur J Gastroenterol Hepatol 16:441-3. 2004
    ..pylori to 'assist'acid suppression obtained by PPI twice-daily, adding bedtime H2RAs after successful H. pylori eradication or other approaches to eliminate NAB results in better clinical outcomes...
  5. ncbi request reprint Gastroesophageal reflux disease: natural history and long-term medical and surgical outcomes
    Radu Tutuian
    Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Clin Cornerstone 5:51-7; discussion 58-60. 2003
    ..Careful selection of appropriate surgical candidates is important, and the risk of developing new or recurrent symptoms requiring medication should be disclosed to patients contemplating the surgical alternative...
  6. ncbi request reprint Diagnosis of laryngopharyngeal reflux
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Curr Opin Otolaryngol Head Neck Surg 12:174-9. 2004
    ..Laryngopharyngeal reflux is of great interest to otolaryngologists, speech and language therapists, and gastroenterologists. This is a brief review of recent publications in the diagnosis of laryngopharyngeal reflux...
  7. ncbi request reprint Disposable balloon-based oesophageal motility catheters: comparison with solid-state transducers
    R Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, Charleston, SC 29425, USA
    Neurogastroenterol Motil 17:453-7. 2005
    ..Recently developed single-use disposable catheters use small balloons prefilled with air that transmit the pressure of oesophageal contractions to external transducers...
  8. ncbi request reprint Reflux monitoring: role of combined multichannel intraluminal impedance and pH
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, 96 Jonathan Lucas Street, 210 CSB, Charleston, SC 29425, USA
    Gastrointest Endosc Clin N Am 15:361-71. 2005
    ..Combined MII-pH is a useful tool in evaluating patients with persistent symptoms on acid-suppressive therapy, patients with atypical symptoms, and infants...
  9. ncbi request reprint Multichannel intraluminal impedance: general principles and technical issues
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, 96 Jonathan Lucas Street, 210 CSB, Charleston, SC 29425, USA
    Gastrointest Endosc Clin N Am 15:257-64. 2005
    ....
  10. ncbi request reprint Esophageal function testing with combined multichannel intraluminal impedance and manometry: multicenter study in healthy volunteers
    Radu Tutuian
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Clin Gastroenterol Hepatol 1:174-82. 2003
    ..Normative data for this method have not been published. The aim of this study was to establish normative data for combined MII-EM and to correlate liquid and viscous bolus transit by impedance with esophageal contractions by manometry...
  11. ncbi request reprint The acidity index: a simple approach to the measurement of gastric acidity
    R Tutuian
    Division of Gastroenterology, Medical University of South Carolina, Charleston, SC 29425, USA
    Aliment Pharmacol Ther 19:443-8. 2004
    ..This parameter is easy to calculate, but does not identify the actual pH level. Recent studies have recommended the use of the integrated intragastric acidity as a more refined method of assessing intragastric acid control...
  12. ncbi request reprint Barrett's esophagus prevalence and epidemiology
    Radu Tutuian
    Division of Gastroenterology and Hepatology, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 210, CSB, Charleston, SC 29425, USA
    Gastrointest Endosc Clin N Am 13:227-32. 2003
    ..An unexplained genetic factor must be present, however, to explain the predominance of BE in white middle-aged men...
  13. ncbi request reprint Esophageal function testing: role of combined multichannel intraluminal impedance and manometry
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, 96 Jonathan Lucas Street, 210 CSB, Charleston, SC 29425, USA
    Gastrointest Endosc Clin N Am 15:265-75. 2005
    ....
  14. ncbi request reprint Multichannel intraluminal impedance in esophageal function testing and gastroesophageal reflux monitoring
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Clin Gastroenterol 37:206-15. 2003
    ..MII-pH shows promise to become an important clinical tool, particularly to assess gastroesophageal reflux in the postprandial period and in patients with persistent symptoms on therapy and with atypical symptoms...
  15. ncbi request reprint Management of gastroesophageal reflux disease
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, Charleston 29425, USA
    Am J Med Sci 326:309-18. 2003
    ..Endoscopic antireflux procedures are recommended only in selected patients and given the relative short experience with these techniques, patients treated with endoscopic procedures should be enrolled in a rigorous follow-up program...
  16. ncbi request reprint Nonacid reflux in patients with chronic cough on acid-suppressive therapy
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, Charleston, 29425, USA
    Chest 130:386-91. 2006
    ..Aim: To evaluate the frequency of chronic cough associated with nonacid reflux and the response of these patients to laparoscopic Nissen fundoplication...
  17. ncbi request reprint Effects of a 5-HT(4) receptor agonist on oesophageal function and gastro-oesophageal reflux: studies using combined impedance-manometry and combined impedance-pH
    R Tutuian
    Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, SC 29425, USA
    Aliment Pharmacol Ther 24:155-62. 2006
    ..5-HT(4) receptor agonists are used as promotility agents of the stomach, small and large intestine. There is limited information on the influence of 5-HT(4) receptor agonists on oesophageal function and gastro-oesophageal reflux...
  18. ncbi request reprint Effect of interval between swallows on oesophageal pressures and bolus movement in normal subjects - Studies with combined multichannel intraluminal impedance and oesophageal manometry
    R Tutuian
    Medical University of South Carolina, Charleston, SC 29425, USA
    Neurogastroenterol Motil 16:23-9. 2004
    ....
  19. ncbi request reprint Clinical relevance of the nutcracker esophagus: suggested revision of criteria for diagnosis
    Amit Agrawal
    Digestive Diseases Center, Medical University of South Carolina, Charleston, SC 29425, USA
    J Clin Gastroenterol 40:504-9. 2006
    ..This threshold has been selected as it exceeds the average DEA in healthy volunteers by 2 SDs. Since its introduction the clinical significance of this finding has been challenged, as many patients with NE are asymptomatic...
  20. ncbi request reprint The influence of rapid food intake on postprandial reflux: studies in healthy volunteers
    Stephan M Wildi
    Digestive Disease Center, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425, USA
    Am J Gastroenterol 99:1645-51. 2004
    ..Our hypothesis was that rapid food intake overstresses the gastric pressure-volume response and contributes to increased postprandial GER...
  21. ncbi request reprint Symptom and function heterogenicity among patients with distal esophageal spasm: studies using combined impedance-manometry
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425, USA
    Am J Gastroenterol 101:464-9. 2006
    ..The aim of our study was to evaluate esophageal bolus transit in patients with manometrically defined distal esophageal spasm (DES)...
  22. doi request reprint Manometry and impedance characteristics of achalasia. Facts and myths
    Amit Agrawal
    Digestive Diseases Center, Medical University of South Carolina, Charleston, SC 29425, USA
    J Clin Gastroenterol 42:266-70. 2008
    ..Combined multichannel intraluminal impedance and esophageal manometry (MII-EM) allows both a functional and a manometric evaluation of esophageal motility and identifies chronic fluid retention...
  23. doi request reprint Addition of a H2 receptor antagonist to PPI improves acid control and decreases nocturnal acid breakthrough
    Inder Mainie
    Division of Gastroenterology and Hepatology, Medical University South Carolina, Charleston, SC 29425, USA
    J Clin Gastroenterol 42:676-9. 2008
    ..The addition of a bedtime H2 receptor antagonist (H2RA) to proton pump inhibitor (PPI) b.i.d. to inhibit nocturnal acid breakthrough (NAB) is controversial. H2RA tolerance has been documented suggesting limitations in its long-term effect...
  24. pmc Functional aspects of distal oesophageal spasm: the role of onset velocity and contraction amplitude on bolus transit
    Daniel Pohl
    Digestive Disease Center, Division of Gastroenterology and Hepatology, Medical University of South Carolina, USA
    Dig Liver Dis 44:569-75. 2012
    ..Distal oesophageal spasm is a rare and under-investigated motility abnormality. Recent studies indicate effective bolus transit in varying percentages of distal oesophageal spasm patients...
  25. ncbi request reprint Bethanechol improves smooth muscle function in patients with severe ineffective esophageal motility
    Amit Agrawal
    Digestive Diseases Center, Medical University of South Carolina, Charleston, SC 29425, USA
    J Clin Gastroenterol 41:366-70. 2007
    ..Bethanechol, a direct-acting muscarinic receptor agonist, has been shown in healthy volunteers to produce a significant increase in peristaltic amplitude in the distal esophagus...
  26. doi request reprint Characteristics of symptomatic reflux episodes on Acid suppressive therapy
    Radu Tutuian
    Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Gastroenterol 103:1090-6. 2008
    ..Persistent symptoms on acid suppressive therapy are due to either acid or nonacid gastroesophageal reflux (GER) episodes or are not related to reflux...
  27. ncbi request reprint Regional esophageal dysfunction in scleroderma and achalasia using multichannel intraluminal impedance and manometry
    Inder Mainie
    Gastroenterology and Hepatology, Medical University South Carolina, Charleston, SC 29425, USA
    Dig Dis Sci 53:210-6. 2008
    ..Combined multichannel intraluminal impedance and manometry (MII-EM) enables the simultaneous measurement of intraesophageal pressures and bolus transit at various levels within the esophagus...
  28. ncbi request reprint Combined multichannel intraluminal impedance and manometry clarifies esophageal function abnormalities: study in 350 patients
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, South Carolina 29425, USA
    Am J Gastroenterol 99:1011-9. 2004
    ..Combined multichannel intraluminal impedance and esophageal manometry (MII-EM) is a technique that uses an FDA-approved device allowing simultaneous evaluation of bolus transit (MII) in relation to pressure changes (EM)...
  29. ncbi request reprint Ingestion of acidic foods mimics gastroesophageal reflux during pH monitoring
    Amit Agrawal
    Digestive Diseases Center, Medical University of South Carolina, Charleston, South Carolina, USA
    Dig Dis Sci 50:1916-20. 2005
    ..Current findings support the recommendations to carefully instruct patients to record all oral intake and to exclude meal periods from the analysis...
  30. ncbi request reprint Laparoscopic Nissen fundoplication after biopolymer injection: a case report
    Amit Agrawal
    Digestive Diseases Center, Medical University of South Carolina, Charleston, 29425, USA
    Gastrointest Endosc 63:520-2. 2006
  31. ncbi request reprint Comparison between the combined analysis and the DeMeester Score to predict response to PPI therapy
    Inder Mainie
    Division of Gastroenterology and Hepatology, Medical University South Carolina, Charleston, SC, USA
    J Clin Gastroenterol 40:602-5. 2006
    ..Combined analysis (CA) including the SI and percentage time pH<4 provides a more comprehensive interpretation of pH monitoring results...
  32. pmc Non-acid gastroesophageal reflux: documenting its relationship to symptoms using multichannel intraluminal impedance (MII)
    Donald O Castell
    Division of Gastroenterology Hepatology, Medical University of South Carolina, Charleston, SC 29425, USA
    Trans Am Clin Climatol Assoc 116:321-33; discussion 333-4. 2005
    ..MII-pH shows promise to become an important clinical tool, particularly to assess GER in the postprandial period and in patients with persistent symptoms on acid suppression therapy...
  33. ncbi request reprint Are 10 wet swallows an appropriate sample of esophageal motility? Yes and no
    Sajid Jalil
    Division of Gastroenterology and Hepatology, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425, USA
    J Clin Gastroenterol 38:30-4. 2004
    ..Given this relative small number of swallows concerns have been raised whether the abnormal findings based on 10 wet swallows would persist with another set of 10 wet swallows...
  34. doi request reprint Reflux monitoring: pH-metry, Bilitec and oesophageal impedance measurements
    Daniel Pohl
    Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, SC 29425, USA
    Best Pract Res Clin Gastroenterol 23:299-311. 2009
    ..The present review summarises the technical aspects in performing and interpreting esophageal reflux monitoring procedures...
  35. ncbi request reprint Use of multichannel intraluminal impedance to document proximal esophageal and pharyngeal nonacidic reflux episodes
    Radu Tutuian
    Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston 29425, USA
    Am J Med 115:119S-123S. 2003
    ..The ability to associate symptoms with nonacid reflux events will help guide therapy in select groups of patients, such as patients with ongoing symptoms on acid-suppressive therapy as well as in the pediatric population...
  36. ncbi request reprint Successful use of phosphodiesterase type 5 inhibitors to control symptomatic esophageal hypercontractility: a case report
    Amit Agrawal
    Digestive Diseases Center, Medical University of South Carolina, 96 Jonathan Lucas Street, 210 Clinical Sciences Building, Charleston, South Carolina 29425, USA
    Dig Dis Sci 50:2059-62. 2005
  37. doi request reprint Multichannel intraluminal impedance and esophageal manometry data for unrestricted swallowing: establishing normal values
    J A Wilson
    Digestive Disease Center, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Dis Esophagus 21:51-6. 2008
    ..MII-EM can be used to collect data with minimal variability in healthy subjects during unrestricted upright meal consumption. This technique may be used to identify abnormal motility patterns during physiologic swallowing...
  38. doi request reprint Symptoms with acid and nonacid reflux may be produced by different mechanisms
    A Agrawal
    Digestive Diseases Center, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Dis Esophagus 22:467-70. 2009
    ..Patients with acid reflux are likely to perceive symptoms earlier, and symptoms with acid and nonacid reflux may be produced by different mechanisms...
  39. ncbi request reprint Identification of hiatal hernia by esophageal manometry: is it reliable?
    A Agrawal
    Digestive Diseases Center, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Dis Esophagus 18:316-9. 2005
    ..Manometric identification of an hiatal hernia is an infrequent finding with low sensitivity but high specificity compared to endoscopy...
  40. pmc Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy: a multicentre study using combined ambulatory impedance-pH monitoring
    I Mainie
    Division of Gastroenterology and Hepatology, Medical University South Carolina, 96 Jonathan Lucas St, 210 Clinical Science Building, PO Box 250327 Charleston, SC 29425, USA
    Gut 55:1398-402. 2006
    ..Using this technique, we aimed to characterise the frequency of acid and non-acid reflux (NAR) and their relationship to typical and atypical GOR symptoms in patients on PPI therapy...
  41. ncbi request reprint Combined multichannel intraluminal impedance-pH monitoring to select patients with persistent gastro-oesophageal reflux for laparoscopic Nissen fundoplication
    I Mainie
    Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Br J Surg 93:1483-7. 2006
    ..The aim of this study was to assess laparoscopic Nissen fundoplication as a treatment for patients with persistent symptoms associated with reflux despite acid suppression documented by MII-pH monitoring...
  42. ncbi request reprint Histamine-2 receptor antagonists at night improve gastroesophageal reflux disease symptoms for patients on proton pump inhibitor therapy
    A Rackoff
    Digestive Diseases Center, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Dis Esophagus 18:370-3. 2005
    ..Further prospective, placebo-controlled studies may help confirm that there is a role for night-time H2RAs in GERD symptom control...
  43. ncbi request reprint Review article: the pathophysiology of gastro-oesophageal reflux disease - oesophageal manifestations
    D O Castell
    Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA
    Aliment Pharmacol Ther 20:14-25. 2004
    ..In sum, GERD is a complex problem caused by many factors that are exacerbated when the patient is in the supine position...
  44. pmc Fundoplication eliminates chronic cough due to non-acid reflux identified by impedance pH monitoring
    I Mainie
    Division of Gastroenterology and Hepatology, Medical University South Carolina, 96 Jonathan Lucas Street, 210 Clinical Science Building, P O Box 250327 Charleston, SC 29425, USA
    Thorax 60:521-3. 2005
    ..We report the case of a 45 year old woman with a history of a chronic cough referred for fundoplication after documenting her symptoms were associated with non-acid reflux using multichannel intraluminal impedance and pH (MII-pH)...
  45. ncbi request reprint The changing paradigm of GERD
    Donald Castell
    Medical University of South Carolina, 96 Jonathan Lucas Street, CSB 210, Charleston, SC 29425, USA
    Curr Gastroenterol Rep 9:441-2. 2007
  46. pmc Nocturnal acid breakthrough - approach to management
    Radu Tutuian
    Division of Gastroenterology Hepatology, Medical University of South Carolina, Charleston, South Carolina, USA
    MedGenMed 6:11. 2004
    ..In our experience, the addition of bedtime H2RAs is clinically effective in controlling nocturnal acid breakthrough and GERD symptoms...
  47. ncbi request reprint Detection of occult liver metastases during EUS for staging of malignancies
    Priyajit Prasad
    Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, South Carolina USA
    Gastrointest Endosc 59:49-53. 2004
    ..EUS is commonly used in the staging of GI, thoracic, and other malignancies. Studies suggest EUS can detect occult liver metastases, but the frequency with which this occurs is unknown...
  48. ncbi request reprint Influence of bolus consistency and position on esophageal high-resolution manometry findings
    Anita Bernhard
    Division of Gastroenterology and Hepatology, University Hospital of Zurich, Zurich, Switzerland
    Dig Dis Sci 53:1198-205. 2008
    ..Conventional esophageal manometry evaluating liquid swallows in the recumbent position measures pressure changes at a limited number of sites and does not assess motility during solid swallows in the physiologic upright position...
  49. ncbi request reprint Diffuse esophageal spasm: not diffuse but distal esophageal spasm (DES)
    Monicca Sperandio
    Department of Medicine, Graduate Hospital, Philadelphia, Pennsylvania, USA
    Dig Dis Sci 48:1380-4. 2003
    ..In conclusion, these findings suggest that the term diffuse esophageal spasm is a misnomer and the DES is more appropriately described as "distal" esophageal spasm...
  50. ncbi request reprint Achalasia: an overview of diagnosis and treatment
    Daniel Pohl
    Division of Gastroenterology and Hepatology, University Hospital Zurich, Raemistrasse 100, CH 8091 Zurich, Switzerland
    J Gastrointestin Liver Dis 16:297-303. 2007
    ..In summary, diagnosis achalasia requires shrewd history taking and dedicated esophageal testing. In experienced hands, treatment of achalasia can provide long-term sustained clinical improvement...
  51. doi request reprint Characteristics of the esophageal low-pressure zone in healthy volunteers and patients with esophageal symptoms: assessment by high-resolution manometry
    Daniel Pohl
    Division of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland
    Am J Gastroenterol 103:2544-9. 2008
    ..While preliminary studies indicate that a bolus might be retained in this area, the clinical relevance of the LPZ remains unclear...
  52. ncbi request reprint Limited diagnostic value of laryngopharyngeal lesions in patients with gastroesophageal reflux during routine upper gastrointestinal endoscopy
    Stephan R Vavricka
    Department of Internal Medicine, Division of Gastroenterology, University Hospital, Zurich, Switzerland
    Am J Gastroenterol 102:716-22. 2007
    ..The prevalence of those lesions in GERD patients is not well established. The aim of this study was to evaluate the prevalence of GERD signs in the laryngopharyngeal area during routine upper gastrointestinal endoscopy...
  53. ncbi request reprint The limitations of pH monitoring for detecting gastroesophageal reflux
    Inder Mainie
    Clin Gastroenterol Hepatol 4:1184; author reply 1185. 2006
  54. ncbi request reprint The role of proximal pH monitoring
    Inder Mainie
    Am J Gastroenterol 100:1621-2. 2005
  55. ncbi request reprint Twenty-four hour ambulatory simultaneous impedance and pH monitoring: a multicenter report of normal values from 60 healthy volunteers
    Steven Shay
    Department of Gastroenterology, Cleveland Clinic Foundation, OH 44195, USA
    Am J Gastroenterol 99:1037-43. 2004
    ....
  56. ncbi request reprint Esophageal pH monitoring: wireless does not mean worry less
    Radu Tutuian
    J Clin Gastroenterol 40:91-2. 2006
  57. ncbi request reprint Pressure details from the weight-challenged gastroesophageal junction: more than the usual suspects
    Radu Tutuian
    Gastroenterology 130:988-9. 2006
  58. ncbi request reprint Intragastric acidity after switching from 5-day treatment with intravenous pantoprazole 40 mg/d to 5-day treatment with oral esomeprazole 40 mg/d or pantoprazole 40 mg/d: an open-label crossover study in healthy adult volunteers
    Philip B Miner
    Oklahoma Foundation for Digestive Research, Oklahoma City, 73104, USA
    Clin Ther 28:725-33. 2006
    ..Oral esomeprazole might control intragastric acidity more effectively compared with other acid-suppressive agents after IV therapy...
  59. ncbi request reprint Esophageal pH monitoring on PPI therapy: removing the blinders
    Radu Tutuian
    Am J Gastroenterol 100:1893-4; author reply 1894. 2005
  60. ncbi request reprint Technology review: Esophageal impedance monitoring
    Albert J Bredenoord
    Department of Gastroenterology, St Antonius Hospital, Nieuwegein, The Netherlands
    Am J Gastroenterol 102:187-94. 2007
    ..The results of several studies suggest that impedance-pH monitoring is useful in the evaluation of patients with PPI-resistant typical reflux symptoms, chronic unexplained cough, excessive belching, and rumination...
  61. ncbi request reprint Oesophageal intraluminal impedance can identify subtle bolus transit abnormalities in patients with mild oesophagitis
    Daniel Sifrim
    Centre for Gastroenterological Research, Catholic University of Leuven, O and N Gasthiusberg, Leuven, Belgium
    Eur J Gastroenterol Hepatol 17:303-5. 2005
    ..Outcome data are needed to evaluate the prognostic value of combined manometry-impedance in patients with GORD undergoing anti-reflux surgery...
  62. doi request reprint Efficacy of laparoscopic mesh-augmented hiatoplasty in GERD and symptomatic hiatal hernia. Study using combined impedance-pH monitoring
    Georg R Linke
    Department of Surgery, Kantonsspital St Gallen, 9007 St Gallen, Switzerland
    J Gastrointest Surg 12:816-21. 2008
    ..Laparoscopic mesh-augmented hiatoplasty (LMAH) might be an alternative operation aimed at restoring the intra-abdominal part of the esophagus and reducing the size of the diaphragmatic hiatus...
  63. ncbi request reprint Update in the diagnosis of gastroesophageal reflux disease
    Radu Tutuian
    Division of Gastroenterology and Hepatology, University Hospital Zurich, Ramistrasse 100, CH 8091 Zurich, Switzerland
    J Gastrointestin Liver Dis 15:243-7. 2006
    ..In the recent years combined multichannel intraluminal impedance and pH (MII-pH) monitoring has become a clinical tool that permits the clarification of the mechanisms underlying the persistent symptoms on acid suppressive therapy...
  64. ncbi request reprint Pneumatic dilatations for achalasia: a safe and effective choice for most patients
    Radu Tutuian
    Am J Gastroenterol 101:2441-2. 2006
  65. ncbi request reprint Reflux monitoring: current status
    Radu Tutuian
    University Hospital Zurich, Division of Gastroenterology and Hepatology, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Curr Gastroenterol Rep 10:263-70. 2008
    ..Combined impedance-pH monitoring offers the ability to identify reflux episodes independently of their acid content, an important advantage when evaluating patients with symptoms persisting during acid-suppressive therapy...
  66. ncbi request reprint Altered esophageal motility and gastroesophageal barrier in patients with jejunal interposition after distal esophageal resection for early stage adenocarcinoma
    Georg R Linke
    Department of Surgery, Kantonsspital St Gallen, 9007 St Gallen, Switzerland
    J Gastrointest Surg 11:1262-7. 2007
    ..The aim of this study was to assess the frequency of acid and nonacid refluxes after Merendino procedure using multichannel intraluminal impedance-pH (MII-pH) monitoring...
  67. ncbi request reprint Profile of GERD in the adult population of a northeast urban community
    Ramesh Srinivasan
    University of Texas Medical Branch, Galveston, Texas, USA
    J Clin Gastroenterol 38:651-7. 2004
    ..Four-hundred and ten surveys were completed from a population sample with demographics comparable to those of the 1990 US Census data...