Vera L Tarakanova
Affiliation: Medical College of Wisconsin
- Mboko W, Rekow M, Ledwith M, Lange P, Schmitz K, Anderson S, et al. Interferon Regulatory Factor 1 and Type I Interferon Cooperate To Control Acute Gammaherpesvirus Infection. J Virol. 2017;91: pubmed publisher..Specifically, both type I IFN receptor and IRF-1 expression potentiated antiviral effects of type II IFN to restrict gammaherpesvirus replication in vivo, in the lungs, and in vitro, in primary macrophage cultures. ..
- Tarakanova V, Molleston J, Goodwin M, Virgin H. MHV68 complement regulatory protein facilitates MHV68 replication in primary macrophages in a complement independent manner. Virology. 2010;396:323-8 pubmed publisher..This study shows a novel, complement independent cell-type-specific function of a gammaherpesvirus RCA protein...
- Darrah E, Kulinski J, Mboko W, Xin G, Malherbe L, Gauld S, et al. B Cell-Specific Expression of Ataxia-Telangiectasia Mutated Protein Kinase Promotes Chronic Gammaherpesvirus Infection. J Virol. 2017;91: pubmed publisher..Thus, our study defines a proviral role of B cell-specific ATM expression during chronic gammaherpesvirus infection. ..
- Darrah E, Stoltz K, Ledwith M, Tarakanova V. ATM supports gammaherpesvirus replication by attenuating type I interferon pathway. Virology. 2017;510:137-146 pubmed publisher..This study identifies attenuation of type I IFN responses as the primary mechanism underlying proviral function of ATM during gammaherpesvirus infection. ..