Jeffrey A Switzer

Summary

Affiliation: Medical College of Georgia
Country: USA

Publications

  1. ncbi request reprint Statins in stroke: prevention, protection and recovery
    Jeffrey A Switzer
    Department of Neurology, Medical College of Georgia, Augusta, GA 30912, USA
    Expert Rev Neurother 6:195-202. 2006
  2. ncbi request reprint Pathophysiology and treatment of stroke in sickle-cell disease: present and future
    Jeffrey A Switzer
    Department of Neurology, Medical College of Georgia, Augusta, GA 30912, USA
    Lancet Neurol 5:501-12. 2006
  3. pmc Matrix metalloproteinase-9 in an exploratory trial of intravenous minocycline for acute ischemic stroke
    Jeffrey A Switzer
    Department of Neurology, Medical College of Georgia, 1122 15th Street, Augusta, GA 30912, USA
    Stroke 42:2633-5. 2011
  4. doi request reprint Simplified modified rankin scale questionnaire: reproducibility over the telephone and validation with quality of life
    Askiel Bruno
    Department of Neurology, Medical College of Georgia, Augusta, GA 30912, USA
    Stroke 42:2276-9. 2011
  5. doi request reprint Minocycline to improve neurologic outcome in stroke (MINOS): a dose-finding study
    Susan C Fagan
    Departmentof Neurology, College of Pharmacy, University of Georgia, Medical College of Georgia, Augusta, GA 30912, USA
    Stroke 41:2283-7. 2010
  6. doi request reprint Simplified modified Rankin Scale questionnaire correlates with stroke severity
    Askiel Bruno
    Department of Neurology, Georgia Health Sciences University, GA, USA
    Clin Rehabil 27:724-7. 2013
  7. doi request reprint Impact of primary stroke center certification on location of acute ischemic stroke care in Georgia
    Jeffrey A Switzer
    Department of Neurology, Georgia Health Sciences University, Augusta, GA 30912, USA
    Stroke 43:1415-7. 2012
  8. doi request reprint Measured neurological improvements correlate with self-perceived improvements after stroke
    Askiel Bruno
    Department of Neurology, Georgia Health Sciences University School of Medicine, Augusta, Georgia 30912, USA
    J Stroke Cerebrovasc Dis 21:659-61. 2012
  9. doi request reprint Overcoming challenges to sustain a telestroke network
    Jeffrey A Switzer
    Department of Neurology, Georgia Health Sciences University, Augusta, Georgia, USA
    J Stroke Cerebrovasc Dis 21:535-40. 2012
  10. doi request reprint Clinical experience with three-factor prothrombin complex concentrate to reverse warfarin anticoagulation in intracranial hemorrhage
    Jeffrey A Switzer
    Department of Neurology, Georgia Health Sciences University, 1122 15th Street, Augusta, GA 30912, USA
    Stroke 43:2500-2. 2012

Detail Information

Publications22

  1. ncbi request reprint Statins in stroke: prevention, protection and recovery
    Jeffrey A Switzer
    Department of Neurology, Medical College of Georgia, Augusta, GA 30912, USA
    Expert Rev Neurother 6:195-202. 2006
    ..In addition, statins may have benefits in neuroprotection and recovery after stroke. The mechanisms by which statins protect against, and improve outcome after, stroke probably extend beyond lipid lowering...
  2. ncbi request reprint Pathophysiology and treatment of stroke in sickle-cell disease: present and future
    Jeffrey A Switzer
    Department of Neurology, Medical College of Georgia, Augusta, GA 30912, USA
    Lancet Neurol 5:501-12. 2006
    ..Here we review the epidemiology, clinical spectrum, and pathophysiology of stroke in sickle-cell disease to identify potential therapeutic targets...
  3. pmc Matrix metalloproteinase-9 in an exploratory trial of intravenous minocycline for acute ischemic stroke
    Jeffrey A Switzer
    Department of Neurology, Medical College of Georgia, 1122 15th Street, Augusta, GA 30912, USA
    Stroke 42:2633-5. 2011
    ..Plasma matrix metalloproteinase-9 levels predict posttissue plasminogen activator (tPA) hemorrhage...
  4. doi request reprint Simplified modified rankin scale questionnaire: reproducibility over the telephone and validation with quality of life
    Askiel Bruno
    Department of Neurology, Medical College of Georgia, Augusta, GA 30912, USA
    Stroke 42:2276-9. 2011
    ..The simplified modified Rankin Scale questionnaire (smRSq) enables a reliable and rapid determination of the modified Rankin Scale score after stroke. We test the reliability and validity of a slightly revised smRSq...
  5. doi request reprint Minocycline to improve neurologic outcome in stroke (MINOS): a dose-finding study
    Susan C Fagan
    Departmentof Neurology, College of Pharmacy, University of Georgia, Medical College of Georgia, Augusta, GA 30912, USA
    Stroke 41:2283-7. 2010
    ..Minocycline is a promising anti-inflammatory and protease inhibitor that is effective in multiple preclinical stroke models. We conducted an early phase trial of intravenous minocycline in acute ischemic stroke...
  6. doi request reprint Simplified modified Rankin Scale questionnaire correlates with stroke severity
    Askiel Bruno
    Department of Neurology, Georgia Health Sciences University, GA, USA
    Clin Rehabil 27:724-7. 2013
    ..To further validate the simplified modified Rankin Scale questionnaire (smRSq), we compare it here to a well-established predictor of functional outcome after stroke, the initial stroke severity...
  7. doi request reprint Impact of primary stroke center certification on location of acute ischemic stroke care in Georgia
    Jeffrey A Switzer
    Department of Neurology, Georgia Health Sciences University, Augusta, GA 30912, USA
    Stroke 43:1415-7. 2012
    ..We investigated the impact of PSC certification on hospital stroke discharge patterns in Georgia communities with a choice between PSC and non-PSC...
  8. doi request reprint Measured neurological improvements correlate with self-perceived improvements after stroke
    Askiel Bruno
    Department of Neurology, Georgia Health Sciences University School of Medicine, Augusta, Georgia 30912, USA
    J Stroke Cerebrovasc Dis 21:659-61. 2012
    ..We compared percent improvement on the National Institutes of Health stroke scale (NIHSS) to stroke outcome that seems tangible to patients and caregivers: their perceived percent improvement...
  9. doi request reprint Overcoming challenges to sustain a telestroke network
    Jeffrey A Switzer
    Department of Neurology, Georgia Health Sciences University, Augusta, Georgia, USA
    J Stroke Cerebrovasc Dis 21:535-40. 2012
    ....
  10. doi request reprint Clinical experience with three-factor prothrombin complex concentrate to reverse warfarin anticoagulation in intracranial hemorrhage
    Jeffrey A Switzer
    Department of Neurology, Georgia Health Sciences University, 1122 15th Street, Augusta, GA 30912, USA
    Stroke 43:2500-2. 2012
    ..The purpose of this study was to review our experience with 3-factor PCC (Profilnine) in the setting of warfarin-associated intracranial hemorrhage (wICH)...
  11. doi request reprint Cost-effectiveness of hub-and-spoke telestroke networks for the management of acute ischemic stroke from the hospitals' perspectives
    Jeffrey A Switzer
    Georgia Health Sciences University, Augusta, GA, USA
    Circ Cardiovasc Qual Outcomes 6:18-26. 2013
    ..This study assessed the cost-effectiveness of a telestroke network in the management of acute ischemic stroke from the perspectives of a network, a hub hospital, and a spoke hospital...
  12. doi request reprint Stroke size correlates with functional outcome on the simplified modified rankin scale questionnaire
    Askiel Bruno
    Department of Neurology, Georgia Health Sciences University, Augusta, Georgia Electronic address
    J Stroke Cerebrovasc Dis 22:781-3. 2013
    ..Acute stroke size is one of the factors impacting functional outcome. To further validate the simplified modified Rankin Scale questionnaire (smRSq), we tested its correlation with stroke size...
  13. doi request reprint Improving modified Rankin Scale assessment with a simplified questionnaire
    Askiel Bruno
    Department of Neurology, Medical College of Georgia, 1120 15th Street BI 3076, Augusta, GA 30912, USA
    Stroke 41:1048-50. 2010
    ..The modified Rankin Scale (mRS) is a popular primary stroke outcome measure, but its usefulness is limited by suboptimal reliability (inter-rater agreement)...
  14. doi request reprint Are limb-shaking transient ischemic attacks a risk factor for postendarterectomy hemorrhage? Case report and literature review
    Jeffrey A Switzer
    Medical College of Georgia Neurology, Augusta, GA 30909, USA
    J Neuroimaging 18:96-100. 2008
    ..We propose that patients with limb-shaking transient ischemic attacks have loss of vasomotor reactivity placing them at high risk for carotid reperfusion syndrome and hemorrhage into the revascularized territory...
  15. ncbi request reprint Development of regional programs to speed treatment of stroke
    Jeffrey A Switzer
    Department of Neurology, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912, USA
    Curr Neurol Neurosci Rep 8:35-42. 2008
    ..Telestroke may be the best alternative in this scenario, extending acute stroke therapies to patients who would otherwise not receive treatment...
  16. pmc Increased hemorrhagic transformation and altered infarct size and localization after experimental stroke in a rat model type 2 diabetes
    Adviye Ergul
    Program in Clinical and Experimental Therapeutics, College of Pharmacy, University of Georgia, USA
    BMC Neurol 7:33. 2007
    ..Diabetes is a risk factor for stroke as well as poor outcome of stroke. The current study tested the hypothesis that diabetes-induced changes in the cerebral vasculature increase the risk of HT and augment ischemic injury...
  17. ncbi request reprint A telestroke network enhances recruitment into acute stroke clinical trials
    Jeffrey A Switzer
    DO, Department of Neurology, Medical College of Georgia, 1122 15th St, Augusta, GA 30912
    Stroke 41:566-9. 2010
    ..To save time, efforts are needed to enroll clinical trial subjects and begin the research drug at the remote site under telemedicine guidance...
  18. doi request reprint A web-based telestroke system facilitates rapid treatment of acute ischemic stroke patients in rural emergency departments
    Jeffrey A Switzer
    Department of Neurology, Medical College of Georgia, Augusta, Georgia 30912, USA
    J Emerg Med 36:12-8. 2009
    ..8 min in other published systems. REACH, a web-based telestroke system, facilitates the safe administration of thrombolytic therapy to patients within rural communities suffering an acute ischemic stroke...
  19. doi request reprint Telestroke 10 years later--'telestroke 2.0'
    Jeffrey A Switzer
    Department of Neurology, Medical College of Georgia, Augusta, GA 30912, USA
    Cerebrovasc Dis 28:323-30. 2009
    ..The lack of physicians with specialty stroke training represents a significant challenge to the future of stroke. This deficit limits both quality stroke care and clinical research initiatives...
  20. pmc Use of telemedicine and helicopter transport to improve stroke care in remote locations
    Mihaela Saler
    Department of Neurology, Georgia Health Sciences University, 1122 15th Street, Augusta, GA, 30912, USA
    Curr Treat Options Cardiovasc Med 13:215-24. 2011
    ..A cost-benefit analysis of telestroke is needed, although the recent proliferation of telestroke networks suggests an economic asset to some hospital systems...
  21. ncbi request reprint Carotid stenosis: endarterectomy or angioplasty and stenting?
    Jeffrey A Switzer
    Jeffrey A Switzer, DO Medical College of Georgia, 1122 15th Street, Augusta, GA 30912, USA
    Curr Treat Options Neurol 9:451-62. 2007
    ..However, it is unlikely that asymptomatic patients or symptomatic patients with moderate stenosis considered at high risk for endarterectomy would benefit from any intervention...
  22. ncbi request reprint Statin therapy for coronary heart disease and its effect on stroke
    Jeffrey A Switzer
    Curr Atheroscler Rep 8:337-42. 2006
    ....