C Strange

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. doi request reprint Airway disease in alpha-1 antitrypsin deficiency
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina 29425 6300, USA
    COPD 10:68-73. 2013
  2. pmc Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency
    Woo Jin Kim
    Channing Laboratory and the Division of Pulmonary and Critical Care Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    Respir Res 13:16. 2012
  3. pmc Pharmacokinetic comparability of Prolastin®-C to Prolastin® in alpha₁-antitrypsin deficiency: a randomized study
    James M Stocks
    Department of Medicine, University of Texas Health Science Center at Tyler, 75708 3154, USA
    BMC Clin Pharmacol 10:13. 2010
  4. ncbi request reprint Results of a survey of patients with alpha-1 antitrypsin deficiency
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Medical University of South Carolina, Charleston, 29425, USA
    Respiration 73:185-90. 2006
  5. pmc Bronchoalveolar lavage and response to cyclophosphamide in scleroderma interstitial lung disease
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, MUSC, 96 Jonathan Lucas Street, 812 CSB, Charleston, SC 29425, USA
    Am J Respir Crit Care Med 177:91-8. 2008
  6. ncbi request reprint Infection in the intensive care unit: a clinician's view of the role of imaging
    Charlie Strange
    Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425, USA
    Semin Roentgenol 42:7-10. 2007
  7. ncbi request reprint Interstitial lung disease in the patient who has connective tissue disease
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, 96 Jonathan Lucas Street, 812 CSB, Charleston, SC 29425, USA
    Clin Chest Med 25:549-59, vii. 2004
  8. ncbi request reprint Genetic testing of minors for alpha1-antitrypsin deficiency
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston 29425, USA
    Arch Pediatr Adolesc Med 160:531-4. 2006
  9. pmc Design of the Endobronchial Valve for Emphysema Palliation Trial (VENT): a non-surgical method of lung volume reduction
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston, SC, USA
    BMC Pulm Med 7:10. 2007
  10. ncbi request reprint Hemodynamic effects of epoprostenol in patients with systemic sclerosis and pulmonary hypertension
    C Strange
    Division of Pulmonary and Critical Care Medicine, Allergy and Clinical Immunology, Medical University of South Carolina, Charleston, USA
    Chest 118:1077-82. 2000

Detail Information

Publications43

  1. doi request reprint Airway disease in alpha-1 antitrypsin deficiency
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina 29425 6300, USA
    COPD 10:68-73. 2013
    ..Whether airways disease improves with AAT augmentation therapy remains unknown...
  2. pmc Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency
    Woo Jin Kim
    Channing Laboratory and the Division of Pulmonary and Critical Care Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    Respir Res 13:16. 2012
    ..We investigated whether SNPs in the chromosome 15q region would be modifiers for lung function and COPD in AAT deficiency...
  3. pmc Pharmacokinetic comparability of Prolastin®-C to Prolastin® in alpha₁-antitrypsin deficiency: a randomized study
    James M Stocks
    Department of Medicine, University of Texas Health Science Center at Tyler, 75708 3154, USA
    BMC Clin Pharmacol 10:13. 2010
    ..The pharmacokinetic comparability of Prolastin-C to Prolastin was assessed in subjects with AAT deficiency...
  4. ncbi request reprint Results of a survey of patients with alpha-1 antitrypsin deficiency
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Medical University of South Carolina, Charleston, 29425, USA
    Respiration 73:185-90. 2006
    ..alpha(1)-Antitrypsin deficiency (AATD) is an uncommon genetic disease which occurs in 1-2.5% of Americans with chronic obstructive pulmonary disease (COPD). Little is known about current demographics of AATD...
  5. pmc Bronchoalveolar lavage and response to cyclophosphamide in scleroderma interstitial lung disease
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, MUSC, 96 Jonathan Lucas Street, 812 CSB, Charleston, SC 29425, USA
    Am J Respir Crit Care Med 177:91-8. 2008
    ..The presence of inflammatory cells on bronchoalveolar lavage is often used to predict disease activity and the need for therapy in systemic sclerosis-associated interstitial lung disease...
  6. ncbi request reprint Infection in the intensive care unit: a clinician's view of the role of imaging
    Charlie Strange
    Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425, USA
    Semin Roentgenol 42:7-10. 2007
  7. ncbi request reprint Interstitial lung disease in the patient who has connective tissue disease
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, 96 Jonathan Lucas Street, 812 CSB, Charleston, SC 29425, USA
    Clin Chest Med 25:549-59, vii. 2004
    ..Additionally, the challenge of finding the patient who has occult connective tissue disease in an interstitial lung disease clinic is discussed...
  8. ncbi request reprint Genetic testing of minors for alpha1-antitrypsin deficiency
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston 29425, USA
    Arch Pediatr Adolesc Med 160:531-4. 2006
    ..Alpha(1)-antitrypsin deficiency (AATD) is a genetic disorder primarily affecting the lungs and liver of affected individuals, causing severe panlobular emphysema and cirrhosis...
  9. pmc Design of the Endobronchial Valve for Emphysema Palliation Trial (VENT): a non-surgical method of lung volume reduction
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston, SC, USA
    BMC Pulm Med 7:10. 2007
    ....
  10. ncbi request reprint Hemodynamic effects of epoprostenol in patients with systemic sclerosis and pulmonary hypertension
    C Strange
    Division of Pulmonary and Critical Care Medicine, Allergy and Clinical Immunology, Medical University of South Carolina, Charleston, USA
    Chest 118:1077-82. 2000
    ..To determine the cause of pulmonary hypertension (PH) in systemic sclerosis (SSc) patients since PH can occur because of pulmonary arteriopathy, pulmonary parenchymal destruction, and left ventricular cardiac dysfunction...
  11. ncbi request reprint Pleural complications in the intensive care unit
    C Strange
    Medical Intensive Care Unit, Medical University of South Carolina, Charleston, USA
    Clin Chest Med 20:317-27. 1999
    ..Correct diagnosis and therapy of pleural effusions will assist in improving pulmonary physiology and outcome in the ICU patient...
  12. ncbi request reprint Pulmonary hypertension in interstitial lung disease
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, Allergy and Clinical Immunology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Curr Opin Pulm Med 11:452-5. 2005
    ..Antifibrotic therapies for interstitial lung disease remain unproved; therefore, some interest has been focused on treating the pulmonary vascular impairment these diseases...
  13. ncbi request reprint Bullous sarcoidosis: a report of three cases
    M A Judson
    Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston 29425, USA
    Chest 114:1474-8. 1998
    ..Additional clues are the presence of mediastinal adenopathy on a chest radiograph or a CT scan and a history consistent with extrapulmonary sarcoidosis...
  14. ncbi request reprint Pneumothorax in cystic fibrosis
    Patrick A Flume
    Department of Medicine, Medical University of South Carolina, 96 Jonathan Lucas St, 812 CSB, Charleston, SC 29425, USA
    Chest 128:720-8. 2005
    ..An understanding of the pathophysiology of this complication and its consequences is important for the management of patients with CF...
  15. doi request reprint A 56-year-old woman with arm pain, dyspnea, and an elevated diaphragm
    Meena Kalluri
    Medical University of South Carolina, Division of Pulmonary and Critical Care, 96 Jonathan Lucas St, 812CSB, Charleston, SC 29425, USA
    Chest 133:296-9. 2008
  16. doi request reprint Pulmonary manifestations of systemic lupus erythematosus
    Diane L Kamen
    Medical University of South Carolina, Charleston, SC 29425, USA
    Clin Chest Med 31:479-88. 2010
    ..Finding the true prevalence of lung involvement with SLE is complicated by the high rates of pulmonary infections. This article reviews the diverse clinical symptoms and immunologic pulmonary manifestations of SLE...
  17. ncbi request reprint Treatment of pulmonary arterial hypertension: a preliminary decision analysis
    Kristin B Highland
    Division of Pulmonary, Critical Care, Allergy, and Clinical Immunology, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 812 CSB, Charleston, SC 29425, USA
    Chest 124:2087-92. 2003
    ..Clinicians must chose between very different therapies without the availability of comparison studies. We constructed a "virtual" clinical trial to help inform these treatment choices...
  18. ncbi request reprint Long-term effects of inhaled corticosteroids on FEV1 in patients with chronic obstructive pulmonary disease. A meta-analysis
    Kristin B Highland
    Division of Pulmonary, Critical Care, Allergy and Clinical Immunology, Medical University of South Carolina, 96 Jonathan Lucas Street, 812 CSB, Box 250623, Charleston, South Carolina 29425, USA
    Ann Intern Med 138:969-73. 2003
    ..There is no consensus on the effectiveness of inhaled corticosteroids for the treatment of chronic obstructive pulmonary disease (COPD)...
  19. ncbi request reprint Does genetic testing result in behavioral health change? Changes in smoking behavior following testing for alpha-1 antitrypsin deficiency
    Matthew J Carpenter
    Medical University of South Carolina, Hollings Cancer Center, Department of Psychiatry and Behavioral Sciences, Charleston, SC 29425, USA
    Ann Behav Med 33:22-8. 2007
    ..As genetic testing for health risk becomes increasingly available, it becomes important to study the prospective impact of testing on modifiable health behavior...
  20. pmc Effects of 1-year treatment with cyclophosphamide on outcomes at 2 years in scleroderma lung disease
    Donald P Tashkin
    Department of Medicine, David Geffen School of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095 1690, USA
    Am J Respir Crit Care Med 176:1026-34. 2007
    ..Although treatment-related benefits in pulmonary function, skin scores, and patient-centered outcomes were demonstrated after 1 year of therapy, the duration of benefit beyond 1 year was unclear...
  21. doi request reprint Radiation therapy for palliation of Eisenmenger's syndrome-associated painful splenomegaly
    Jonathan I Osorio
    School of Medicine Medical University of South Carolina, Charleston, SC 29425, USA
    Radiat Med 26:84-7. 2008
    ..0-2.5 Gy per fraction to a total dose approaching 40 Gy for adequate duration of response when treating cardiogenic-associated painful splenomegaly in patients for whom surgical splenectomy cannot be performed...
  22. ncbi request reprint Evaluation of an intensive insulin protocol for septic patients in a medical intensive care unit
    Stephanie B Clayton
    Department of Pharmacy Services, Medical University of South Carolina, Charleston, SC, USA
    Crit Care Med 34:2974-8. 2006
    ..We prospectively evaluated the implementation of an intensive insulin protocol in medical intensive care patients to identify and overcome obstacles that this complex therapy creates...
  23. ncbi request reprint Genetic testing for alpha1-antitrypsin deficiency
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, 96 Jonathan Lucas Street, 812 CSB, Charleston, SC 29425, USA
    Genet Med 6:204-10. 2004
    ..The Alpha Coded Testing Study investigated the risks, benefits, and psychological impact of home genetic testing for alpha1-antitrypsin deficiency...
  24. ncbi request reprint Management of spontaneous pneumothorax: an American College of Chest Physicians Delphi consensus statement
    M H Baumann
    Division of Pulmonary and Critical Care Medicine, University of Mississippi Medical Center, Jackson, MS 39216 4505, USA
    Chest 119:590-602. 2001
    ..The guideline was designed to be relevant to physicians who make management decisions for the care of patients with pneumothorax...
  25. ncbi request reprint Multi-center study: the biochemical efficacy, safety and tolerability of a new alpha1-proteinase inhibitor, Zemaira
    James M Stocks
    The University of Texas Health Center at Tyler, 11937 US Hwy 271, Tyler, TX 75708 3154, USA
    COPD 3:17-23. 2006
    ..These results demonstrate that the new plasma derived alpha1-PI (Zemaira) is bioequivalent to the currently available product Prolastin, is well tolerated, and safe with respect to the risk of viral transmission...
  26. pmc IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency
    Dawn L DeMeo
    Brigham and Women s Hospital, Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Am J Respir Cell Mol Biol 38:114-20. 2008
    ..Haplotype analysis of IL10 SNPs suggested the strongest association with IL10 promoter SNPs. IL10 is likely an important modifier gene for the development of COPD in individuals with severe AAT deficiency...
  27. doi request reprint High-resolution CT scan findings in patients with symptomatic scleroderma-related interstitial lung disease
    Jonathan G Goldin
    David Geffen School of Medicine at UCLA, Department of Radiology, Los Angeles, CA 90095 1721, USA
    Chest 134:358-67. 2008
    ..The frequency, nature, and progression of interstitial lung disease seen on high-resolution CT (HRCT) scans in patients with diffuse SSc (dcSSc) compared with those with limited SSc (lcSSc) has not been well characterized...
  28. doi request reprint Defining appropriate outcome measures in pulmonary arterial hypertension related to systemic sclerosis: a Delphi consensus study with cluster analysis
    Oliver Distler
    University Hospital Zurich, Zurich, Switzerland
    Arthritis Rheum 59:867-75. 2008
    ..The aim of the present study was to establish an expert consensus regarding which outcome measures are most appropriate for clinical trials in PAH-SSc...
  29. doi request reprint Scleroderma lung disease: "if you don't know where you are going, any road will take you there"
    Charlie Strange
    Am J Respir Crit Care Med 177:1178-9. 2008
  30. doi request reprint alpha1-Antitrypsin augmentation therapy for PI*MZ heterozygotes: a cautionary note
    Robert A Sandhaus
    National Jewish Medical and Research Center, Denver, CO, USA
    Chest 134:831-4. 2008
    ..This commentary discusses the treatment of AAT deficiency and the concerns regarding treatment of PI*MZ individuals. We conclude that clinicians should avoid prescribing augmentation therapy for this heterozygote population...
  31. ncbi request reprint Factors associated with advanced liver disease in adults with alpha1-antitrypsin deficiency
    Christopher L Bowlus
    Division of Gastroenterology, University of California at Davis, UC Davis Medical Center, 4150 V Street, PSSB 3500, Sacramento, CA 95817, USA
    Clin Gastroenterol Hepatol 3:390-6. 2005
    ..Our study aim was to characterize the liver disease in AAT and identify factors associated with advanced liver disease...
  32. ncbi request reprint Primary care diagnosis of alpha-1 antitrypsin deficiency: issues and opportunities
    James K Stoller
    Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, USA
    Cleve Clin J Med 74:869-74. 2007
    ..The authors discuss impediments to diagnosis and drivers to making the diagnosis of alpha-1 antitrypsin deficiency, and they suggest several measures to enhance clinicians' recognition of the condition...
  33. pmc Determinants of airflow obstruction in severe alpha-1-antitrypsin deficiency
    Dawn L DeMeo
    Channing Laboratory, 181 Longwood Avenue, Boston, Massachusetts 02115, USA
    Thorax 62:806-13. 2007
    ..A study was undertaken to assess the impact of chronic bronchitis, pneumonia, asthma and sex on the development of COPD in individuals with severe AAT deficiency...
  34. ncbi request reprint Asthma and allergy in alpha-1 antitrypsin deficiency
    Edward Eden
    Department of Pulmonary and Critical Care Medicine, St Luke s Roosevelt Hospital, Columbia University, New York, NY, USA
    Respir Med 100:1384-91. 2006
    ..Those with AATD who are susceptible to asthma require allergy evaluation and aggressive anti-inflammatory strategies as part of their management...
  35. ncbi request reprint Cyclophosphamide versus placebo in scleroderma lung disease
    Donald P Tashkin
    University of California at Los Angeles, Los Angeles, USA
    N Engl J Med 354:2655-66. 2006
    ....
  36. ncbi request reprint Impact of oral cyclophosphamide on health-related quality of life in patients with active scleroderma lung disease: results from the scleroderma lung study
    Dinesh Khanna
    University of Cincinnati, Cincinnati, Ohio 45267 0563, USA
    Arthritis Rheum 56:1676-84. 2007
    ..To assess the impact of cyclophosphamide (CYC) on the health-related quality of life (HRQOL) of patients with scleroderma after 12 months of treatment...
  37. ncbi request reprint Alpha-1 Foundation research registry: from the past to the future
    Charlie Strange
    J Pediatr Gastroenterol Nutr 34:1. 2002
  38. ncbi request reprint "The lion, the witch and the wardrobe": impact on sibs of individuals with AAT deficiency
    Joanna H Fanos
    Research Institute and Department of Pediatrics, California Pacific Medical Center, San Francisco, California 94115, USA
    Am J Med Genet A 130:251-7. 2004
    ..4) Awareness of liver disease from AAT deficiency should be increased...
  39. ncbi request reprint Delay in diagnosis of alpha1-antitrypsin deficiency: a continuing problem
    James K Stoller
    Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic Foundation, A 90, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Chest 128:1989-94. 2005
    ..We also determined whether individuals living near medical centers with an expressed interest in AAT deficiency experienced shorter diagnostic delays than those living at a distance...
  40. doi request reprint Sitaxsentan for the treatment of pulmonary arterial hypertension: a 1-year, prospective, open-label observation of outcome and survival
    Raymond L Benza
    University of Alabama at Birmingham, 1900 University Blvd, Tinsley Harrison Towers, Room 328A, Birmingham, AL 35294, USA
    Chest 134:775-82. 2008
    ..Long-term efficacy evaluations are needed to guide therapeutic management. The purpose of this study is to present 1-year observational data with two endothelin antagonists, sitaxsentan and bosentan, in a prospective, open-label study...
  41. ncbi request reprint Treatment for secondary pulmonary hypertension
    Charlie Strange
    Chest 128:1897-8. 2005
  42. ncbi request reprint Mortality in individuals with severe deficiency of alpha1-antitrypsin: findings from the National Heart, Lung, and Blood Institute Registry
    James K Stoller
    Department of Pulmonary, Allergy, and Critical Care Medicine, The Cleveland Clinic Foundation, 9500 Euclid Ave, A90, Cleveland, OH 44195, USA
    Chest 127:1196-204. 2005
    ..2 years)...