Jennifer L Strande

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. ncbi request reprint SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts
    Jennifer L Strande
    Division of Cardiovascular Medicine, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    Basic Res Cardiol 102:350-8. 2007
  2. pmc Gadolinium decreases inflammation related to myocardial ischemia and reperfusion injury
    Jennifer L Strande
    Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    J Inflamm (Lond) 6:34. 2009
  3. pmc Parstatin: a cryptic peptide involved in cardioprotection after ischaemia and reperfusion injury
    Jennifer L Strande
    Division of Cardiovascular Medicine, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, USA
    Cardiovasc Res 83:325-34. 2009
  4. pmc Thrombin increases inflammatory cytokine and angiogenic growth factor secretion in human adipose cells in vitro
    Jennifer L Strande
    Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
    J Inflamm (Lond) 6:4. 2009
  5. pmc Inhibiting protease-activated receptor 4 limits myocardial ischemia/reperfusion injury in rat hearts by unmasking adenosine signaling
    Jennifer L Strande
    Division of Cardiovascular Medicine, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    J Pharmacol Exp Ther 324:1045-54. 2008
  6. pmc Gadolinium limits myocardial infarction in the rat: dose-response, temporal relations and mechanisms
    Alfred C Nicolosi
    Division of Cardiothoracic Surgery, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    J Mol Cell Cardiol 44:345-51. 2008
  7. pmc 10 Gy total body irradiation increases risk of coronary sclerosis, degeneration of heart structure and function in a rat model
    John E Baker
    Division of Cardiothoracic Surgery, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Int J Radiat Biol 85:1089-100. 2009
  8. doi request reprint Parstatin(1-26): the putative signal peptide of protease-activated receptor 1 confers potent protection from myocardial ischemia-reperfusion injury
    Kasi V Routhu
    Division of Cardiovascular Medicine, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    J Pharmacol Exp Ther 332:898-905. 2010
  9. pmc Protease-activated receptor 1 inhibition by SCH79797 attenuates left ventricular remodeling and profibrotic activities of cardiac fibroblasts
    Dmitry L Sonin
    Division of Cardiovascular Medicine, Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI, USA
    J Cardiovasc Pharmacol Ther 18:460-75. 2013
  10. pmc Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats
    John E Baker
    Division of Cardiothoracic Surgery, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Cardiovasc Res 77:44-53. 2008

Detail Information

Publications11

  1. ncbi request reprint SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts
    Jennifer L Strande
    Division of Cardiovascular Medicine, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    Basic Res Cardiol 102:350-8. 2007
    ....
  2. pmc Gadolinium decreases inflammation related to myocardial ischemia and reperfusion injury
    Jennifer L Strande
    Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    J Inflamm (Lond) 6:34. 2009
    ..We determined the impact of GdCl3 treatment for reperfusion injury on 1) circulating monoctye and neutrophil counts, 2) secretion of inflammatory cytokines, and 3) influx of monocytes and neutrophils into the myocardium...
  3. pmc Parstatin: a cryptic peptide involved in cardioprotection after ischaemia and reperfusion injury
    Jennifer L Strande
    Division of Cardiovascular Medicine, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, USA
    Cardiovasc Res 83:325-34. 2009
    ..Although much research has focused on the activated receptor, little is known about the 41-amino acid N-terminal peptide (parstatin). We hypothesized that parstatin would protect the heart against ischaemia-reperfusion injury...
  4. pmc Thrombin increases inflammatory cytokine and angiogenic growth factor secretion in human adipose cells in vitro
    Jennifer L Strande
    Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
    J Inflamm (Lond) 6:4. 2009
    ..Therefore, the purpose of this study was to examine the expression of thrombin receptors (PAR1 and PAR4) human adipose tissue and whether thrombin stimulates an inflammatory cytokine and growth factor profile in human adipose tissue...
  5. pmc Inhibiting protease-activated receptor 4 limits myocardial ischemia/reperfusion injury in rat hearts by unmasking adenosine signaling
    Jennifer L Strande
    Division of Cardiovascular Medicine, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    J Pharmacol Exp Ther 324:1045-54. 2008
    ..Thrombin receptor blockade by PAR4 inhibition provides protection against injury from myocardial I/R by unmasking adenosine receptor signaling and supports the hypothesis of a coupling between thrombin receptors and adenosine receptors...
  6. pmc Gadolinium limits myocardial infarction in the rat: dose-response, temporal relations and mechanisms
    Alfred C Nicolosi
    Division of Cardiothoracic Surgery, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    J Mol Cell Cardiol 44:345-51. 2008
    ..The mechanism underlying Gd-induced preconditioning appears to be multi-factorial, involving JAK-2, STAT-3 and p44 MAPK pathways, as well as K(ATP) channels...
  7. pmc 10 Gy total body irradiation increases risk of coronary sclerosis, degeneration of heart structure and function in a rat model
    John E Baker
    Division of Cardiothoracic Surgery, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Int J Radiat Biol 85:1089-100. 2009
    ..To determine the impact of 10 Gy total body irradiation (TBI) or local thorax irradiation, a dose relevant to a radiological terrorist threat, on lipid and liver profile, coronary microvasculature and ventricular function...
  8. doi request reprint Parstatin(1-26): the putative signal peptide of protease-activated receptor 1 confers potent protection from myocardial ischemia-reperfusion injury
    Kasi V Routhu
    Division of Cardiovascular Medicine, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    J Pharmacol Exp Ther 332:898-905. 2010
    ..This suggests that parstatin(1-26) has a potential therapeutic role in the treatment of ischemia and reperfusion injury...
  9. pmc Protease-activated receptor 1 inhibition by SCH79797 attenuates left ventricular remodeling and profibrotic activities of cardiac fibroblasts
    Dmitry L Sonin
    Division of Cardiovascular Medicine, Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI, USA
    J Cardiovasc Pharmacol Ther 18:460-75. 2013
    ....
  10. pmc Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats
    John E Baker
    Division of Cardiothoracic Surgery, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Cardiovasc Res 77:44-53. 2008
    ..Thrombopoietin (Tpo) is known for its ability to stimulate platelet production. However, it is currently unknown whether Tpo plays a physiological function in the heart...
  11. doi request reprint Nerve growth factor reduces myocardial ischemia/reperfusion injury in rat hearts
    Jennifer L Strande
    Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
    J Basic Clin Physiol Pharmacol 24:81-4. 2013
    ..However, it is unclear whether NGF protects the heart during infarct. In this study, we sought to address this issue in rat heart exposed to ischemia/reperfusion injury (IRI)...