Rashmi Sood

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. doi request reprint Thrombophilia and fetal loss: Lessons from gene targeting in mice
    Rashmi Sood
    Medical College of Wisconsin, Milwaukee, WI, USA
    Thromb Res 123:S79-84. 2009
  2. pmc Maternal Par4 and platelets contribute to defective placenta formation in mouse embryos lacking thrombomodulin
    Rashmi Sood
    Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Blood 112:585-91. 2008
  3. pmc Fetal gene defects precipitate platelet-mediated pregnancy failure in factor V Leiden mothers
    Rashmi Sood
    Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI 53226, USA
    J Exp Med 204:1049-56. 2007
  4. pmc Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C
    Edward J Kerschen
    Blood Research Institute, Milwaukee, WI 53226, USA
    J Exp Med 204:2439-48. 2007
  5. pmc Caveolin-1-dependent apoptosis induced by fibrin degradation products
    Yi He Guo
    Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI 53226 3548, USA
    Blood 113:4431-9. 2009
  6. pmc Fetomaternal cross talk in the placental vascular bed: control of coagulation by trophoblast cells
    Rashmi Sood
    Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI 53226, USA
    Blood 107:3173-80. 2006
  7. ncbi request reprint Cause-effect relation between hyperfibrinogenemia and vascular disease
    Bryce Kerlin
    Blood Research Institute, Blood Center of SE Wisconsin, Milwaukee 53226, USA
    Blood 103:1728-34. 2004
  8. doi request reprint Heparin rescues factor V Leiden-associated placental failure independent of anticoagulation in a murine high-risk pregnancy model
    Jianzhong An
    Division of Pediatric Pathology, Department of Pathology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Blood 121:2127-34. 2013
  9. ncbi request reprint The thrombomodulin-protein C system is essential for the maintenance of pregnancy
    Berend Isermann
    Blood Research Institute, The Blood Center of Southeastern Wisconsin, Milwaukee, Wisconsin, USA
    Nat Med 9:331-7. 2003
  10. ncbi request reprint Survival advantage associated with heterozygous factor V Leiden mutation in patients with severe sepsis and in mouse endotoxemia
    Bryce A Kerlin
    Blood Research Institute, Blood Center of Southeast Wisconsin and Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Blood 102:3085-92. 2003

Collaborators

Detail Information

Publications11

  1. doi request reprint Thrombophilia and fetal loss: Lessons from gene targeting in mice
    Rashmi Sood
    Medical College of Wisconsin, Milwaukee, WI, USA
    Thromb Res 123:S79-84. 2009
    ..Genetically engineered mice have led to the development of new insights into the etiology and pathogenesis of thrombophilia-associated fetal loss. These insights are the focus of this review...
  2. pmc Maternal Par4 and platelets contribute to defective placenta formation in mouse embryos lacking thrombomodulin
    Rashmi Sood
    Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Blood 112:585-91. 2008
    ..Our findings demonstrate that fetal prothrombotic mutations can cause localized activation of maternal platelets at the feto-maternal interface in a mother with normal hemostatic function...
  3. pmc Fetal gene defects precipitate platelet-mediated pregnancy failure in factor V Leiden mothers
    Rashmi Sood
    Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI 53226, USA
    J Exp Med 204:1049-56. 2007
    ..e., thrombosis or pregnancy loss), depending on the vascular bed in which this interaction occurs...
  4. pmc Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C
    Edward J Kerschen
    Blood Research Institute, Milwaukee, WI 53226, USA
    J Exp Med 204:2439-48. 2007
    ....
  5. pmc Caveolin-1-dependent apoptosis induced by fibrin degradation products
    Yi He Guo
    Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI 53226 3548, USA
    Blood 113:4431-9. 2009
    ....
  6. pmc Fetomaternal cross talk in the placental vascular bed: control of coagulation by trophoblast cells
    Rashmi Sood
    Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI 53226, USA
    Blood 107:3173-80. 2006
    ....
  7. ncbi request reprint Cause-effect relation between hyperfibrinogenemia and vascular disease
    Bryce Kerlin
    Blood Research Institute, Blood Center of SE Wisconsin, Milwaukee 53226, USA
    Blood 103:1728-34. 2004
    ....
  8. doi request reprint Heparin rescues factor V Leiden-associated placental failure independent of anticoagulation in a murine high-risk pregnancy model
    Jianzhong An
    Division of Pediatric Pathology, Department of Pathology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Blood 121:2127-34. 2013
    ..Importantly, thrombin-mediated maternal platelet activation remains central in the mechanism of placental failure...
  9. ncbi request reprint The thrombomodulin-protein C system is essential for the maintenance of pregnancy
    Berend Isermann
    Blood Research Institute, The Blood Center of Southeastern Wisconsin, Milwaukee, Wisconsin, USA
    Nat Med 9:331-7. 2003
    ..These findings show a new function for the thrombomodulin-protein C system in controlling the growth and survival of trophoblast cells in the placenta. This function is essential for the maintenance of pregnancy...
  10. ncbi request reprint Survival advantage associated with heterozygous factor V Leiden mutation in patients with severe sepsis and in mouse endotoxemia
    Bryce A Kerlin
    Blood Research Institute, Blood Center of Southeast Wisconsin and Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Blood 102:3085-92. 2003
    ..76). The findings suggest that FV Leiden constitutes a rare example of a balanced gene polymorphism that maintains the FV Leiden mutation in the general gene pool due to a survival advantage of VL+/- in severe sepsis...
  11. ncbi request reprint Embryogenesis and gene targeting of coagulation factors in mice
    Rashmi Sood
    Blood Research Institute, The Blood Center of Southeastern Wisconsin, Milwaukee, WI 53226, USA
    Best Pract Res Clin Haematol 16:169-81. 2003
    ..Abnormal signalling by placental trophoblasts at the feto-maternal interface is suggested as a hitherto unrecognized mechanism that may underlie adverse pregnancy outcome associated with haemostatic disorders...