Kit N Simpson

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. ncbi request reprint Decision analysis of the cost-effectiveness of repetitive transcranial magnetic stimulation versus electroconvulsive therapy for treatment of nonpsychotic severe depression
    F Andrew Kozel
    Brain Stimulation Laboratory, Department of Psychiatry, Medical University of South Carolina, and Ralph H Johnson Veterans Affairs Medical Center, Charleston, USA
    CNS Spectr 9:476-82. 2004
  2. ncbi request reprint Cost effectiveness of lopinavir/ritonavir compared with atazanavir in antiretroviral-naive patients: modelling the combined effects of HIV and heart disease
    Kit N Simpson
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Clin Drug Investig 27:67-74. 2007
  3. ncbi request reprint Drivers of Costs Associated With Reperfusion Therapy in Acute Stroke: The Interventional Management of Stroke III Trial
    Kit N Simpson
    From the Department of Neurology and Rehabilitation Medicine, University of Cincinnati Academic Health Center, OH J P B, D K, P K, J A S Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada M D H and Department of Healthcare Leadership and Management K N S, A N S, Department of General Internal Medicine P D M, Department of Public Health Sciences S D Y, L D F, R M, Y Y P, Department of Emergency Medicine E C J, Medical University of South Carolina, Charleston
    Stroke 45:1791-8. 2014
  4. pmc Patient reported outcome instruments used in clinical trials of HIV-infected adults on NNRTI-based therapy: a 10-year review
    Kit N Simpson
    UBC An Express Scripts Company, 185 Dorval Ave, Suite 500, Dorval, QC H9S 5J9, Canada
    Health Qual Life Outcomes 11:164. 2013
  5. pmc Responsiveness of the MOS-HIV and EQ-5D in HIV-infected adults receiving antiretroviral therapies
    Albert W Wu
    Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Health Qual Life Outcomes 11:42. 2013
  6. pmc A mixed methods descriptive investigation of readiness to change in rural hospitals participating in a tele-critical care intervention
    Jane Zapka
    Department of Public Health Sciences, Medical University of South Carolina MUSC, 135 Cannon Street, Charleston, SC 29425, USA
    BMC Health Serv Res 13:33. 2013
  7. doi request reprint Lopinavir/ritonavir versus darunavir plus ritonavir for HIV infection: a cost-effectiveness analysis for the United States
    Kit N Simpson
    Department of Health Leadership and Management, College of Health Professions, Medical University of South Carolina, 151B Rutledge Ave, Room 412, Charleston, SC 29425, USA
    Pharmacoeconomics 31:427-44. 2013
  8. doi request reprint Economics of switching to second-line antiretroviral therapy with lopinavir/ritonavir in Africa: estimates based on DART trial results and costs for Uganda and Kenya
    Kit N Simpson
    Department of Health Leadership and Management, Medical University of South Carolina, Charleston, SC 29425, USA
    Value Health 14:1048-54. 2011
  9. doi request reprint Economic and health-related quality-of-life (HRQoL) comparison of lopinavir/ritonavir (LPV/r) and atazanavir plus ritonavir (ATV+RTV) based regimens for antiretroviral therapy (ART)-naïve and -experienced United Kingdom patients in 2011
    K N Simpson
    Department of Health Science and Research, College of Health Professions, Medical University of South Carolina, SC 29425, USA
    J Med Econ 15:796-806. 2012
  10. doi request reprint Economic analysis of secondary trial data
    Kit N Simpson
    Department of Health Leadership and Management, College of Health Professions, Medical University of South Carolina, Charleston, SC, USA
    Prog Cardiovasc Dis 54:351-6. 2012

Detail Information

Publications48

  1. ncbi request reprint Decision analysis of the cost-effectiveness of repetitive transcranial magnetic stimulation versus electroconvulsive therapy for treatment of nonpsychotic severe depression
    F Andrew Kozel
    Brain Stimulation Laboratory, Department of Psychiatry, Medical University of South Carolina, and Ralph H Johnson Veterans Affairs Medical Center, Charleston, USA
    CNS Spectr 9:476-82. 2004
    ..Repetitive transcranial magnetic stimulation (rTMS) is a new treatment with promise for resistant depression...
  2. ncbi request reprint Cost effectiveness of lopinavir/ritonavir compared with atazanavir in antiretroviral-naive patients: modelling the combined effects of HIV and heart disease
    Kit N Simpson
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Clin Drug Investig 27:67-74. 2007
    ..This study aimed to estimate the long-term combined effects of HIV disease and antiretroviral (ARV)-related risk for CHD on quality-adjusted survival and healthcare costs for ARV-naive patients...
  3. ncbi request reprint Drivers of Costs Associated With Reperfusion Therapy in Acute Stroke: The Interventional Management of Stroke III Trial
    Kit N Simpson
    From the Department of Neurology and Rehabilitation Medicine, University of Cincinnati Academic Health Center, OH J P B, D K, P K, J A S Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada M D H and Department of Healthcare Leadership and Management K N S, A N S, Department of General Internal Medicine P D M, Department of Public Health Sciences S D Y, L D F, R M, Y Y P, Department of Emergency Medicine E C J, Medical University of South Carolina, Charleston
    Stroke 45:1791-8. 2014
    ..This report describes the factors affecting the costs of the initial hospitalization for acute stroke subjects from the United States...
  4. pmc Patient reported outcome instruments used in clinical trials of HIV-infected adults on NNRTI-based therapy: a 10-year review
    Kit N Simpson
    UBC An Express Scripts Company, 185 Dorval Ave, Suite 500, Dorval, QC H9S 5J9, Canada
    Health Qual Life Outcomes 11:164. 2013
    ..Patient-reported outcomes (PROs) may provide valuable information to clinicians and patients when choosing initial antiretroviral therapy...
  5. pmc Responsiveness of the MOS-HIV and EQ-5D in HIV-infected adults receiving antiretroviral therapies
    Albert W Wu
    Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Health Qual Life Outcomes 11:42. 2013
    ....
  6. pmc A mixed methods descriptive investigation of readiness to change in rural hospitals participating in a tele-critical care intervention
    Jane Zapka
    Department of Public Health Sciences, Medical University of South Carolina MUSC, 135 Cannon Street, Charleston, SC 29425, USA
    BMC Health Serv Res 13:33. 2013
    ....
  7. doi request reprint Lopinavir/ritonavir versus darunavir plus ritonavir for HIV infection: a cost-effectiveness analysis for the United States
    Kit N Simpson
    Department of Health Leadership and Management, College of Health Professions, Medical University of South Carolina, 151B Rutledge Ave, Room 412, Charleston, SC 29425, USA
    Pharmacoeconomics 31:427-44. 2013
    ..In order to fully assess the implications of this study, economic modelling extrapolating over a longer term is required...
  8. doi request reprint Economics of switching to second-line antiretroviral therapy with lopinavir/ritonavir in Africa: estimates based on DART trial results and costs for Uganda and Kenya
    Kit N Simpson
    Department of Health Leadership and Management, Medical University of South Carolina, Charleston, SC 29425, USA
    Value Health 14:1048-54. 2011
    ..We use decision analysis modeling to estimate health and economic consequences expected from this switch...
  9. doi request reprint Economic and health-related quality-of-life (HRQoL) comparison of lopinavir/ritonavir (LPV/r) and atazanavir plus ritonavir (ATV+RTV) based regimens for antiretroviral therapy (ART)-naïve and -experienced United Kingdom patients in 2011
    K N Simpson
    Department of Health Science and Research, College of Health Professions, Medical University of South Carolina, SC 29425, USA
    J Med Econ 15:796-806. 2012
    ....
  10. doi request reprint Economic analysis of secondary trial data
    Kit N Simpson
    Department of Health Leadership and Management, College of Health Professions, Medical University of South Carolina, Charleston, SC, USA
    Prog Cardiovasc Dis 54:351-6. 2012
    ..The interpretation of incremental cost-effectiveness ratios is discussed and economic benchmarks for defining good and poor value interventions are provided...
  11. pmc Economic modeling of the combined effects of HIV-disease, cholesterol and lipoatrophy based on ACTG 5142 trial data
    Kit N Simpson
    Medical University of South Carolina, SC, USA
    Cost Eff Resour Alloc 9:5. 2011
    ..abstract:..
  12. doi request reprint Cost-effectiveness of tipranavir in treatment-experienced HIV patients in the United States
    Kit N Simpson
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    HIV Clin Trials 9:225-37. 2008
    ....
  13. ncbi request reprint Cost-effectiveness of lopinavir/ritonavir versus nelfinavir as the first-line highly active antiretroviral therapy regimen for HIV infection
    Kit N Simpson
    Pharmacy and Clinical Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    HIV Clin Trials 5:294-304. 2004
    ..nelfinavir (NFV), both coadministered with stavudine and lamivudine, as the first HAART regimen in treating HIV patients, based on the results from the published clinical trial M98-863...
  14. doi request reprint Cost-effectiveness analysis of lopinavir/ritonavir and atazanavir+ritonavir regimens in the CASTLE study
    Kit N Simpson
    Medical University of South Carolina, 151 B Rutledge Avenue, Room 409, Charleston, South Carolina 29425, USA
    Adv Ther 26:185-93. 2009
    ....
  15. ncbi request reprint Comparison of Markov model and discrete-event simulation techniques for HIV
    Kit N Simpson
    Department of Health Administration and Policy, College of Health Professions, Medical University of South Carolina, Charleston, SC 29425, USA
    Pharmacoeconomics 27:159-65. 2009
    ..Using published results from 48-week trial data as model inputs, Markov model and DES modelling approaches were compared in terms of clinical outcomes at 5 years and lifetime cost-effectiveness estimates...
  16. ncbi request reprint Economic modeling of HIV treatments
    Kit N Simpson
    Department of Health Science and Research, Medical University of South Carolina, Charleston, USA
    Curr Opin HIV AIDS 5:242-8. 2010
    ..Recommend improvements in HIV economic modeling...
  17. ncbi request reprint Cost effectiveness of lopinavir/ritonavir tablets compared with atazanavir plus ritonavir in antiretroviral-experienced patients in the UK, France, Italy and Spain
    Kit N Simpson
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Clin Drug Investig 27:807-17. 2007
    ....
  18. ncbi request reprint Cost effectiveness of lopinavir/ritonavir compared with atazanavir plus ritonavir in antiretroviral-experienced patients in the US
    Kit N Simpson
    Department of Health Administration and Policy, College of Health Professions, Medical University of South Carolina, Charleston, SC 29425, USA
    Clin Drug Investig 27:443-52. 2007
    ..To estimate the cost effectiveness and long-term combined effects of HIV disease and antiretroviral (ARV) therapy-related risk for coronary heart disease (CHD) on quality-adjusted survival and healthcare costs for ARV-experienced patients...
  19. doi request reprint Cost-effectiveness of transcranial magnetic stimulation in the treatment of major depression: a health economics analysis
    Kit N Simpson
    Medical University of South Carolina, 67 President Street, Room 502N, Charleston, SC, 29403, USA
    Adv Ther 26:346-68. 2009
    ..The incremental cost-effectiveness and the direct cost burden compared with sham treatment were estimated, and compared with the current standard of care...
  20. ncbi request reprint Impact of elevated per cent carbohydrate-deficient transferrin at hospital admission on outcomes in trauma patients
    Brian P McKinzie
    South Carolina College of Pharmacy Residency Program, Department of Pharmacy Services, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am Surg 76:492-6. 2010
    ..0052) and ventilator days (2 vs. 1.5 days, P = 0.0286). Complications and hospital charges were similar between groups. Trauma patients presenting to the ETU with %CDT elevations appear to be at risk for longer ICU and hospital LOS...
  21. pmc Design of the economic evaluation for the Interventional Management of Stroke (III) trial
    Patrick D Mauldin
    Department of Pharmacy and Clinical Sciences, Medical University of South Carolina, Ralph H Johnson VA Medical Center, Charleston, SC 29425, USA
    Int J Stroke 3:138-44. 2008
    ..To assist in informing discussions on early adoption of potential treatments, economic analyses should accompany investigations that seek to improve outcomes for stroke patients...
  22. ncbi request reprint The one-year attributable cost of poststroke aphasia
    Charles Ellis
    Medical University of South Carolina, Department of Health Sciences and Research, Charleston, SC 29425, USA
    Stroke 43:1429-31. 2012
    ..Little is known about the contribution of aphasia to the cost of care for patients who experience stroke...
  23. doi request reprint A cost-effectiveness analysis of inhaled corticosteroid delivery for children with asthma in the emergency department
    Annie Lintzenich Andrews
    Department of Pediatrics, Medical University of South Carolina, Charleston, SC 29425, USA
    J Pediatr 161:903-7. 2012
    ..To determine the clinical effectiveness and cost-effectiveness of 3 inhaled corticosteroid (ICS) delivery options for children with asthma treated in and discharged from the emergency department (ED)...
  24. pmc The cost of Medicaid savings: the potential detrimental public health impact of neonatal circumcision defunding
    Annie L Andrews
    Department of Pediatrics, Medical University of South Carolina, 135 Rutledge Avenue, P O Box 250561, Charleston, SC 29425, USA
    Infect Dis Obstet Gynecol 2012:540295. 2012
    ..To project the increased incidence of HIV and subsequent costs resulting from the expected decreased rate of circumcision due to Medicaid defunding in one southeastern state...
  25. ncbi request reprint Treatment of pulmonary arterial hypertension: a preliminary decision analysis
    Kristin B Highland
    Division of Pulmonary, Critical Care, Allergy, and Clinical Immunology, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 812 CSB, Charleston, SC 29425, USA
    Chest 124:2087-92. 2003
    ..Clinicians must chose between very different therapies without the availability of comparison studies. We constructed a "virtual" clinical trial to help inform these treatment choices...
  26. pmc Barriers facing patients referred for kidney transplant cause loss to follow-up
    Abby S Kazley
    Department of Health Care Leadership and Management, Medical University of South Carolina, Charleston, South Carolina 29464, USA
    Kidney Int 82:1018-23. 2012
    ..Thus, patients with end-stage renal disease lost to follow-up after referral for kidney transplant faced both real and perceived barriers pursuing transplantation...
  27. doi request reprint Hospital care for patients experiencing weekend vs weekday stroke: a comparison of quality and aggressiveness of care
    Abby S Kazley
    Department of Health Professions, Medical University of South Carolina, 151 Rutledge Ave, Charleston, SC 29425, USA
    Arch Neurol 67:39-44. 2010
    ..Because of this short treatment window for the administration of tissue plasminogen activator, patients need around-the-clock access to high-quality and aggressive care...
  28. ncbi request reprint Timing of elective repeat cesarean delivery at term and neonatal outcomes: a cost analysis
    Christopher J Robinson
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, SC, USA
    Am J Obstet Gynecol 202:632.e1-6. 2010
    ....
  29. ncbi request reprint Impact of an alcohol withdrawal syndrome practice guideline on surgical patient outcomes
    Karen M Stanley
    Department of Therapeutic Services, Medical University of South Carolina, Charleston 29425, USA
    Pharmacotherapy 23:843-54. 2003
    ..To standardize treatment of alcohol withdrawal syndrome (AWS) in surgical patients using an AWS practice guideline with a symptom-triggered approach...
  30. ncbi request reprint Experience with an adult alcohol withdrawal syndrome practice guideline in internal medicine patients
    Karen M Stanley
    Department of Therapeutic Services, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Pharmacotherapy 25:1073-83. 2005
    ..To standardize treatment of alcohol withdrawal syndrome (AWS) in internal medicine patients using an adult AWS practice guideline with a symptom-triggered management approach...
  31. pmc Muscle architecture predicts maximum strength and is related to activity levels in cerebral palsy
    Noelle G Moreau
    Department of Health Professions, Medical University of South Carolina, 77 President St, MSC 700, Charleston, SC 29425, USA
    Phys Ther 90:1619-30. 2010
    ..Muscle architecture is known to be predictive of muscle function. However, it is unknown whether this relationship is similar in children and adolescents with and without cerebral palsy (CP)...
  32. ncbi request reprint Comparison of self-report versus agency records of service utilization in a community sample of individuals with alcohol use disorders
    Therese K Killeen
    Department of Psychiatry and Behavioral Sciences, Center for Drug and Alcohol Programs, Medical University of South Carolina, 67 President Street 4 North, P O Box 250861, Charleston, SC 29425 0742, USA
    Drug Alcohol Depend 73:141-7. 2004
    ..There was less agreement in emergency room visits and arrests. Factors related to discrepancies between self-report and records were explored...
  33. pmc Polypharmacy: misleading, but manageable
    Reamer L Bushardt
    Department of Clinical Services, Medical University of South Carolina, Charleston, South Carolina, USA
    Clin Interv Aging 3:383-9. 2008
    ..The authors recommend use of less ambiguous terminology such as hyperpharmacotherapy or multiple medication use. A structured approach to identify and manage inappropriate polypharmacy is suggested and a clinical tool is provided...
  34. ncbi request reprint Silent strokes in patients with heart failure
    Thomas Siachos
    Medical University of South Carolina, Charleston, South Carolina, USA
    J Card Fail 11:485-9. 2005
    ..The prevalence of asymptomatic strokes detected by brain imaging in a large cohort of patients with congestive heart failure (CHF) and reduced ejection fraction (EF) is unknown...
  35. ncbi request reprint Health care provider perception of chronic kidney disease: knowledge and behavior among African American patients
    Abby S Kazley
    Department of Health Care Leadership and Management, MUSC, 151 Rutledge Ave, Charleston, SC 29425, USA
    BMC Nephrol 15:112. 2014
    ..The purpose of this study is to determine the knowledge and reactions of chronic kidney disease patients regarding their disease, as perceived by nephrologists and clinic nurses in South Carolina...
  36. pmc Charges for hospital admissions attributable to health disparities for African-American patients, 1998-2002
    Elinor C G Chumney
    Department of Pharmacy and Clinical Sciences, Medical University of South Carolina, Charleston, SC, USA
    J Natl Med Assoc 98:690-4. 2006
    ..Estimates for the financial impact of the racial admission differences for the State of South Carolina are assessed...
  37. doi request reprint Review of the impact of NNRTI-based HIV treatment regimens on patient-reported disease burden
    Kit N Simpson
    a Department of Healthcare Leadership and Management, Medical University of South Carolina, Charleston, SC, USA
    AIDS Care 26:466-75. 2014
    ..Treatments are needed that can also reduce patient burden in areas of emotional well-being, cognitive functioning, and overall symptom profile. ..
  38. doi request reprint Cost-effectiveness of maternal treatment to prevent perinatal hepatitis B virus transmission
    Elizabeth Ramsey Unal
    Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Obstet Gynecol 118:655-62. 2011
    ..To estimate the cost-effectiveness of maternal lamivudine or hepatitis B immune globulin (HBIG) treatment, in addition to standard neonatal immunoprophylaxis, for the prevention of perinatal hepatitis B virus transmission...
  39. doi request reprint Cost effectiveness of an inpatient influenza immunization assessment and delivery program for children with asthma
    Ronald J Teufel
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Hosp Med 3:134-41. 2008
    ..Influenza is common in children. Children with asthma are underimmunized. The Centers for Disease Control recommends immunization in an acute-care hospital setting...
  40. ncbi request reprint Therapeutic inertia is an impediment to achieving the Healthy People 2010 blood pressure control goals
    Eni C Okonofua
    Medical University of South Carolina, Charleston, SC 29425, USA
    Hypertension 47:345-51. 2006
    ..TI has a major impact on BP control in hypertensive subjects receiving regular care. Reducing TI is critical in attaining the Healthy People 2010 goal of controlling hypertension in 50% of all patients...
  41. ncbi request reprint The effect of cost construction based on either DRG or ICD-9 codes or risk group stratification on the resulting cost-effectiveness ratios
    Elinor C G Chumney
    Department of Pharmacy Practice, Medical University of South Carolina, College of Pharmacy, Charleston 29425, USA
    Pharmacoeconomics 22:1209-16. 2004
    ..Yet, the implications of using International Classification of Diseases-9th edition (ICD-9) codes or a form of disease-specific risk group stratification instead of DRGs has yet to be clearly documented...
  42. ncbi request reprint Potential cost savings of decreased emergency department visits through increased continuity in a pediatric medical home
    Patricia G McBurney
    Department of Pediatrics, Medical University of South Carolina, Charleston, SC 29425, USA
    Ambul Pediatr 4:204-8. 2004
    ..To determine the potential cost savings of decreased emergency department (ED) visits resulting from increased continuity of care provided in a pediatric medical home...
  43. doi request reprint Costs and clinical outcomes of noninvasive fetal RhD typing for targeted prophylaxis
    Angela F Hawk
    Department of Obstetrics and Gynecology, College of Health Professions, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Obstet Gynecol 122:579-85. 2013
    ..To examine the cost and clinical outcomes of noninvasive RhD typing with cell-free fetal DNA to selectively deliver antenatal and postnatal prophylaxis with anti-D immune globulin for prevention of alloimmunization in RhD-negative women...
  44. doi request reprint Impact of a hospital-acquired/ventilator-associated/healthcare-associated pneumonia practice guideline on outcomes in surgical trauma patients
    Cathy L Worrall
    Department of Clinical Pharmacy and Outcomes Sciences, South Carolina College of Pharmacy MUSC campus, Charleston, SC, USA
    J Trauma 68:382-6. 2010
    ..This study examined outcomes for two STICU cohorts treated for pneumonia before and after guideline implementation...
  45. ncbi request reprint Effectiveness of naltrexone in a community treatment program
    Therese K Killeen
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, USA
    Alcohol Clin Exp Res 28:1710-7. 2004
    ..Whether this efficacy can be generalized to individuals who have alcohol use disorders and present for treatment at front-line community treatment programs has not been well established...
  46. ncbi request reprint Compliance of an institution-specific alcohol withdrawal protocol with evidence-based practice guidelines
    Karen E Moeller
    Department of Pharmacy Practice, School of Pharmacy, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Pharmacotherapy 26:445-6. 2006
  47. ncbi request reprint Do diabetes group visits lead to lower medical care charges?
    Dawn E Clancy
    Maybank Internal Medicine corrected, USA
    Am J Manag Care 14:39-44. 2008
    ..To evaluate whether attending diabetes group visits (GVs) leads to lower medical care charges for inadequately insured patients with type 2 diabetes mellitus (DM)...
  48. doi request reprint Cost-effectiveness of extended adjuvant rituximab for US patients aged 65-70 years with follicular lymphoma in second remission
    John W Hayslip
    Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA
    Clin Lymphoma Myeloma 8:166-70. 2008
    ..The current study was conducted to determine the incremental cost-effectiveness ratio of this strategy in the United States...