Haowei Shen

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. pmc Heroin relapse requires long-term potentiation-like plasticity mediated by NMDA2b-containing receptors
    Haowei Shen
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Proc Natl Acad Sci U S A 108:19407-12. 2011
  2. doi request reprint Automated quantification of dendritic spine density and spine head diameter in medium spiny neurons of the nucleus accumbens
    Haowei Shen
    Department of Neurosciences, Medical University of South Carolina, 173 Ashley Avenue, BSB 403, Charleston, SC 29425, USA
    Brain Struct Funct 213:149-57. 2008
  3. pmc Role of mGluR5 neurotransmission in reinstated cocaine-seeking
    Xiusong Wang
    Department of Neurosciences, Medical University of South Carolina, Charleston, USA
    Addict Biol 18:40-9. 2013
  4. pmc Relapse induced by cues predicting cocaine depends on rapid, transient synaptic potentiation
    Cassandra D Gipson
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Neuron 77:867-72. 2013
  5. pmc Reversing cocaine-induced synaptic potentiation provides enduring protection from relapse
    Khaled Moussawi
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Proc Natl Acad Sci U S A 108:385-90. 2011
  6. doi request reprint Reduced LTP and LTD in prefrontal cortex synapses in the nucleus accumbens after heroin self-administration
    Haowei Shen
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Int J Neuropsychopharmacol 16:1165-7. 2013
  7. doi request reprint Inhibition of actin polymerization prevents cocaine-induced changes in spine morphology in the nucleus accumbens
    Shigenobu Toda
    Department of Neurosciences, Medical University of South Carolina, 173 Ashley Ave, BSB410, Charleston, SC 29425, USA
    Neurotox Res 18:410-5. 2010
  8. ncbi request reprint NAC1 regulates the recruitment of the proteasome complex into dendritic spines
    Haowei Shen
    Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Neurosci 27:8903-13. 2007
  9. pmc Glutamate transmission in addiction
    Peter W Kalivas
    Department of Neurosciences, 173 Ashley Ave, BSB410, Medical University of South Carolina, Charleston, SC 29464, USA
    Neuropharmacology 56:169-73. 2009

Detail Information

Publications9

  1. pmc Heroin relapse requires long-term potentiation-like plasticity mediated by NMDA2b-containing receptors
    Haowei Shen
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Proc Natl Acad Sci U S A 108:19407-12. 2011
    ..Moreover, the data reveal NR2B-containing NMDA receptors as a previously unexplored therapeutic target for treating heroin addiction...
  2. doi request reprint Automated quantification of dendritic spine density and spine head diameter in medium spiny neurons of the nucleus accumbens
    Haowei Shen
    Department of Neurosciences, Medical University of South Carolina, 173 Ashley Avenue, BSB 403, Charleston, SC 29425, USA
    Brain Struct Funct 213:149-57. 2008
    ..The capacity to rapidly assess spine density and spine head diameter will facilitate quantifying spine plasticity induced by pharmacological and environmental manipulations...
  3. pmc Role of mGluR5 neurotransmission in reinstated cocaine-seeking
    Xiusong Wang
    Department of Neurosciences, Medical University of South Carolina, Charleston, USA
    Addict Biol 18:40-9. 2013
    ..Taken together, these data show that mGluR5 inhibition and stimulation in the NAcore can regulate cocaine-seeking, and demonstrate that one mechanism for this effect is via interactions with Homer proteins...
  4. pmc Relapse induced by cues predicting cocaine depends on rapid, transient synaptic potentiation
    Cassandra D Gipson
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Neuron 77:867-72. 2013
    ..The marked cue-induced synaptic changes in the accumbens were correlated with the intensity of cocaine, but not sucrose seeking, and may explain the difficulty addicts experience in managing relapse to cocaine use...
  5. pmc Reversing cocaine-induced synaptic potentiation provides enduring protection from relapse
    Khaled Moussawi
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Proc Natl Acad Sci U S A 108:385-90. 2011
    ....
  6. doi request reprint Reduced LTP and LTD in prefrontal cortex synapses in the nucleus accumbens after heroin self-administration
    Haowei Shen
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Int J Neuropsychopharmacol 16:1165-7. 2013
    ..These data indicate that compromised synaptic plasticity in prefrontal to accumbens projections is a common feature of at least two distinct classes of addictive drug...
  7. doi request reprint Inhibition of actin polymerization prevents cocaine-induced changes in spine morphology in the nucleus accumbens
    Shigenobu Toda
    Department of Neurosciences, Medical University of South Carolina, 173 Ashley Ave, BSB410, Charleston, SC 29425, USA
    Neurotox Res 18:410-5. 2010
    ....
  8. ncbi request reprint NAC1 regulates the recruitment of the proteasome complex into dendritic spines
    Haowei Shen
    Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Neurosci 27:8903-13. 2007
    ..These experiments show that NAC1 modulates the translocation of the UPS from the nucleus into dendritic spines, thereby suggesting a potential missing link in the recruitment of necessary proteolysis machinery for synaptic remodeling...
  9. pmc Glutamate transmission in addiction
    Peter W Kalivas
    Department of Neurosciences, 173 Ashley Ave, BSB410, Medical University of South Carolina, Charleston, SC 29464, USA
    Neuropharmacology 56:169-73. 2009
    ..This information points to the value of exploring pharmacotherapeutic manipulation of glutamate plasticity in treating drug addiction...