Derek A Schreihofer

Summary

Affiliation: Medical College of Georgia
Country: USA

Publications

  1. doi Phytoestrogens as neuroprotectants
    Derek A Schreihofer
    Department of Physiology, Medical College of Georgia, Georgia 30912 3000, USA
    Drugs Today (Barc) 45:609-27. 2009
  2. pmc Effect of high soy diet on the cerebrovasculature and endothelial nitric oxide synthase in the ovariectomized rat
    Derek A Schreihofer
    Department of Physiology, Medical College of Georgia, Augusta, GA 30912 3000, USA
    Vascul Pharmacol 52:236-42. 2010
  3. pmc Protective effect of estrogen in endothelin-induced middle cerebral artery occlusion in female rats
    Michele L Glendenning
    Department of Physiology, CA3145, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912 3000, United States
    Neurosci Lett 445:188-92. 2008
  4. ncbi High-soy diet decreases infarct size after permanent middle cerebral artery occlusion in female rats
    Derek A Schreihofer
    Department of Physiology, 1120 15th St, CA 3145, Medical College of Georgia, Augusta, GA 30912 3000, USA
    Am J Physiol Regul Integr Comp Physiol 289:R103-8. 2005
  5. doi Dietary genistein and equol (4', 7 isoflavandiol) reduce oxidative stress and protect rats against focal cerebral ischemia
    Yulin Ma
    Department of Physiology, Medical College of Georgia, St, Augusta, GA 30912 3000, USA
    Am J Physiol Regul Integr Comp Physiol 299:R871-7. 2010
  6. doi Hypoxia-inducible factor and vascular endothelial growth factor are targets of dietary soy during acute stroke in female rats
    Yulin Ma
    Department of Physiology, Medical College of Georgia, Augusta, Georgia 30912, USA
    Endocrinology 154:1589-97. 2013
  7. pmc A high soy diet enhances neurotropin receptor and Bcl-XL gene expression in the brains of ovariectomized female rats
    Tara Lovekamp-Swan
    Department of Physiology, CA3145, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912 3000, USA
    Brain Res 1159:54-66. 2007
  8. doi Delayed puberty and estrogen resistance in a woman with estrogen receptor α variant
    Samuel D Quaynor
    Section of Reproductive Endocrinology, Infertility, and Genetics, Department of Obstetrics and Gynecology, Institute of Molecular Medicine and Genetics, and the Neuroscience Program, Medical College of Georgia, Georgia Regents University, Augusta, GA 30912, USA
    N Engl J Med 369:164-71. 2013
  9. pmc The role of aldosterone in mediating the dependence of angiotensin hypertension on IL-6
    Lashon C Sturgis
    Department of Physiology, Medical College of Georgia, Augusta, Georgia 30912 3000, USA
    Am J Physiol Regul Integr Comp Physiol 297:R1742-8. 2009
  10. ncbi Transcriptional regulation by phytoestrogens in neuronal cell lines
    Derek A Schreihofer
    Department of Physiology, Medical College of Georgia, 1120 15th Street, CL2130, Augusta, GA 30912 3000, USA
    Mol Cell Endocrinol 231:13-22. 2005

Collaborators

Detail Information

Publications10

  1. doi Phytoestrogens as neuroprotectants
    Derek A Schreihofer
    Department of Physiology, Medical College of Georgia, Georgia 30912 3000, USA
    Drugs Today (Barc) 45:609-27. 2009
    ....
  2. pmc Effect of high soy diet on the cerebrovasculature and endothelial nitric oxide synthase in the ovariectomized rat
    Derek A Schreihofer
    Department of Physiology, Medical College of Georgia, Augusta, GA 30912 3000, USA
    Vascul Pharmacol 52:236-42. 2010
    ..However, the effects of E2 and HS on the cerebrovasculature are small and may not underlie their protective actions in pathological states...
  3. pmc Protective effect of estrogen in endothelin-induced middle cerebral artery occlusion in female rats
    Michele L Glendenning
    Department of Physiology, CA3145, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912 3000, United States
    Neurosci Lett 445:188-92. 2008
    ..Stroke size was significantly correlated with LDF in both groups, suggesting that cranial perfusion measures can enhance success in this model...
  4. ncbi High-soy diet decreases infarct size after permanent middle cerebral artery occlusion in female rats
    Derek A Schreihofer
    Department of Physiology, 1120 15th St, CA 3145, Medical College of Georgia, Augusta, GA 30912 3000, USA
    Am J Physiol Regul Integr Comp Physiol 289:R103-8. 2005
    ..These data show that 2 wk of a high-soy diet is an effective prophylactic strategy for reducing stroke size in a rat model of focal cerebral ischemia...
  5. doi Dietary genistein and equol (4', 7 isoflavandiol) reduce oxidative stress and protect rats against focal cerebral ischemia
    Yulin Ma
    Department of Physiology, Medical College of Georgia, St, Augusta, GA 30912 3000, USA
    Am J Physiol Regul Integr Comp Physiol 299:R871-7. 2010
    ..These isoflavones may protect the brain via increases in endogenous antioxidant mechanisms and reduced oxidative stress...
  6. doi Hypoxia-inducible factor and vascular endothelial growth factor are targets of dietary soy during acute stroke in female rats
    Yulin Ma
    Department of Physiology, Medical College of Georgia, Augusta, Georgia 30912, USA
    Endocrinology 154:1589-97. 2013
    ..These data suggest that soy isoflavones target events early in the ischemic cascade as part of their neuroprotective actions and counterbalance some of the detrimental effects of the endogenous response to cerebral injury...
  7. pmc A high soy diet enhances neurotropin receptor and Bcl-XL gene expression in the brains of ovariectomized female rats
    Tara Lovekamp-Swan
    Department of Physiology, CA3145, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912 3000, USA
    Brain Res 1159:54-66. 2007
    ..These results suggest that a high soy diet may provide beneficial effects to the brain similar to low dose chronic estrogen treatment such as that used for postmenopausal hormone replacement...
  8. doi Delayed puberty and estrogen resistance in a woman with estrogen receptor α variant
    Samuel D Quaynor
    Section of Reproductive Endocrinology, Infertility, and Genetics, Department of Obstetrics and Gynecology, Institute of Molecular Medicine and Genetics, and the Neuroscience Program, Medical College of Georgia, Georgia Regents University, Augusta, GA 30912, USA
    N Engl J Med 369:164-71. 2013
    ..Her clinical presentation was similar to that in the mouse orthologue knockout. This case shows that disruption of ESR1 causes profound estrogen resistance in women. (Funded by the National Institutes of Health.). ..
  9. pmc The role of aldosterone in mediating the dependence of angiotensin hypertension on IL-6
    Lashon C Sturgis
    Department of Physiology, Medical College of Georgia, Augusta, Georgia 30912 3000, USA
    Am J Physiol Regul Integr Comp Physiol 297:R1742-8. 2009
    ..This suggests that aldosterone contributes to the increase in plasma IL-6 in the early stage of ANG II hypertension but that the blood pressure actions of IL-6 in that model are linked most likely to ANG II rather than aldosterone...
  10. ncbi Transcriptional regulation by phytoestrogens in neuronal cell lines
    Derek A Schreihofer
    Department of Physiology, Medical College of Georgia, 1120 15th Street, CL2130, Augusta, GA 30912 3000, USA
    Mol Cell Endocrinol 231:13-22. 2005
    ....